The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is not significantly correlated to Transient Global Amnesia: Preliminary results of an on-going study in Brescia Province, Italy

Neuroscience Letters

Volumn 443, Issue 3, 2008, Pages 228-231

  Agosti, C ^a   Borroni, B ^a   Archetti, S ^a   Akkawi, N M ^b   Padovani, A ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b Department of Neurology ^*  (Lebanon)

Author keywords

Brain derived neurotrophic factor (BDNF); Genetics; Polymorphism; Transient Global Amnesia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; METHIONINE; VALINE;

ADULT; AGED; AMINO ACID SUBSTITUTION; AMNESIA; ARTICLE; CLINICAL EXAMINATION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE DURATION; DISEASE PREDISPOSITION; FEMALE; GENE FREQUENCY; GENETIC CORRELATION; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; NEUROLOGIC EXAMINATION; ONSET AGE; PRIORITY JOURNAL; RECURRENT DISEASE; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSIENT GLOBAL AMNESIA;

AGED; AMNESIA, TRANSIENT GLOBAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; ITALY; MALE; METHIONINE; MIDDLE AGED; POLYMORPHISM, GENETIC; VALINE;

EID: 50249165318     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.07.082     Document Type: Article

References (33)

1. Agosti C., Borroni B., Akkawi N., and Padovani A. Three sisters covering the transient global amnesia spectrum. Int. Psychogeriatr. 19 (2007) 987-989
2. Akkawi N.M., Agosti C., Rozzini L., Anzola G.P., and Padovani A. Transient global amnesia and venous flow patterns. Lancet 357 (2001) 357: 639
3. Baquet Z.C., Gorski J.A., and Jones K.R. Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor. J. Neurosci. 24 (2004) 4250-4258
4. Bartsch T., Alfke K., Stingele R., Rohr A., Freitag-Wolf S., Jansen O., and Deuschl G. Selective affection of hippocampal CA-1 neurons in patients with transient global amnesia without long-term sequelae. Brain 129 (2006) 2874-2884
5. Chen Z.Y., Jing D., Bath K.G., Ieraci A., Khan T., Siao C.J., Herrera D.G., Toth M., Yang C., McEwen B.S., Hempstead B.L., and Lee F.S. Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science 314 (2006) 140-143
6. Chen Z.Y., Patel P.D., Sant G., Meng C.X., Teng K.K., Hempstead B.L., and Lee F.S. Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J. Neurosci. 24 (2004) 4401-4411
7. Di Filippo M., and Calabresi P. Ischemic bilateral hippocampal dysfunction during transient global amnesia. Neurology 69 (2007) 493
8. Dupuis M.J., Pierre P., and Gonsette R.E. Transient global amnesia and migraine in twin sisters. J. Neurol. Neurosurg. Psychiatry 50 (1987) 816-817
9. Egan M.F., Kojima M., Callicott J.H., Goldberg T.E., Kolachana B.S., Bertolino A., Zaitsev E., Gold B., Goldman D., Dean M., Lu B., and Weinberger D.R. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112 (2003) 257-269
10. Figurov A., Pozzo-Miller L.D., Olafsson P., Wang T., and Lu B. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature 381 (1996) 706-709
11. Fisher C.M., and Adams R.D. Transient global amnesia. Acta Neurol. Scand. 40 (1964) 1-83
12. Gorski J.A., Zeiler S.R., Tamowski S., and Jones K.R. Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites. J. Neurosci. 23 (2003) 6856-6865
13. Guillery-Girard B., Quinette P., Desgranges B., Piolino P., Viader F., de la Sayette V., and Eustache F. Long-term memory following transient global amnesia: an investigation of episodic and semantic memory. Acta Neurol. Scand. 114 (2006) 329-333
14. Guyotat M.M., and Courjon J. Les ictus amnésiques. J. Med. Lyon 37 (1956) 697-701
15. Hanson I.M., Seawright A., and van Heyningen V. The human BDNF gene maps between FSHB and HVBS1at the boundary of 11p13-p14. Genomics 13 (1992) 1331-1333
16. Hariri A.R., Goldberg T.E., Mattay V.S., Kolachana B.S., Callicott J.H., Egan M.F., and Weinberger D.R. Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J. Neurosci. 23 (2003) 6690-6694
17. Hodges J.R., and Warlow C.P. Syndromes of transient amnesia: towards a classification. A study of 153 cases. J. Neurol. Neurosurg. Psychiatry 53 (1990) 834-843
18. Hodges J.R., and Warlow C.P. The aetiology of transient global amnesia. A casecontrol study of 114 cases with prospective follow-up. Brain 113 (1990) 639-657
19. Hua J.Y., and Smith S.J. Neural activity and the dynamics of central nervous system development. Nat. Neurosci. 7 (2004) 327-332
20. Lee H.Y., Kim J.H., Weon Y.C., Lee J.S., Kim S.Y., Youn S.W., and Kim S.H. Diffusion-weighted imaging in transient global amnesia exposes the CA1 region of the hippocampus. Neuroradiology (2007) 481-487
21. Lewis S.L. Aetiology of transient global amnesia. Lancet 352 (1998) 397-399
22. Lu B., and Gottschalk W. Modulation of hippocampal synaptic transmission and plasticity by neurotrophins. Prog. Brain Res. 128 (2000) 231-241
23. Melo T.P., Ferro J.M., and Ferro H. Transient global amnesia A case control study. Brain 115 (1992) 261-270
24. Milner B., Squire L.R., and Kandel E.R. Cognitive neuroscience and the study of memory. Neuron 20 (1998) 445-468
25. Pantoni L., Bertini E., Lamassa M., Pracucci G., and Inzitari D. Clinical features, risk factors and prognosis in transient global amnesia: a follow-up study. Eur. J. Neurol. 12 (2005) 350-356
26. Quinette P., Guillery-Girard B., Dayan J., de la Sayette V., Marquis S., Viader F., Desgranges B., and Eustache F. What does transient global amnesia really mean? Review of the literature andthorough study of 142 cases. Brain 129 (2006) 1640-1658
27. Quinette P., Guillery-Girard B., Noël A., de la Sayette V., Viader F., Desgranges B., and Eustache F. The relationship between working memory and episodic memory disorders in transient global amnesia. Neuropsychologia 44 (2006) 2508-2519
28. Roesler A., Mras G.J., Frese A., Albert I., and Schnorpfeil F. Precipitating factors of transient global amnesia. J. Neurol. 246 (1999) 53-54
29. Sander K., and Sander D. New insights into transient global amnesia: recent imaging and clinical findings. Lancet Neurol. 4 (2005) 437-444
30. Smith M.A., Makino S., Kvetnansky R., and Post R.M. Stress alters the expression of brain-derived neurotrophic factor and neurotrophin-3mRNAs in the hippocampus. J. Neurosci. 15 (1995) 1768-1777
31. Szeszko P.R., Lipsky R., Mentschel C., Robinson D., Gunduz-Bruce H., Sevy S., Ashtari M., Napolitano B., Bilder R.M., Kane J.M., Goldman D., and Malhotra A.K. Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Mol. Psychiatry 10 (2005) 631-636
32. Winbeck K., Etgen T., von Einsiedel H.G., Röttinger M., and Sander D. DWI in transient global amnesia and TIA: proposal for an ischaemic origin of TGA. J. Neurol. Neurosurg. Psychiatry 76 (2005) 438-441
33. Zorzon M., Antonutti L., Mase G., Biasutti E., Vitrani B., and Cazzato G. Transient global amnesia and transient ischemic attack. Natural history, vascular risk factors, and associated conditions. Stroke 26 (1995) 1536-1542