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Volumn 4, Issue 9, 2008, Pages 503-509

How should women with pre-eclampsia be followed up? New insights from mechanistic studies

Author keywords

Gestational hypertension; Glomerular endotheliosis; Pre eclampsia; Pregnancy; sFlt 1

Indexed keywords

ANGIOGENIC FACTOR; AUTOANTIBODY; FIBROBLAST GROWTH FACTOR RECEPTOR 1; VASCULOTROPIN;

EID: 50249147366     PISSN: 17458323     EISSN: 17458331     Source Type: Journal    
DOI: 10.1038/ncpneph0880     Document Type: Review
Times cited : (18)

References (59)
  • 1
    • 14644412849 scopus 로고    scopus 로고
    • Pre-eclampsia
    • Sibai B et al. (2005) Pre-eclampsia. Lancet 365: 785-799
    • (2005) Lancet , vol.365 , pp. 785-799
    • Sibai, B.1
  • 2
    • 0037373006 scopus 로고    scopus 로고
    • Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
    • Maynard SE et al. (2003) Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 111: 649-658
    • (2003) J Clin Invest , vol.111 , pp. 649-658
    • Maynard, S.E.1
  • 3
    • 31844448145 scopus 로고    scopus 로고
    • Mapping the theories of preeclampsia: The need for systematic reviews of mechanisms of the disease
    • Mignini LE (2006) Mapping the theories of preeclampsia: the need for systematic reviews of mechanisms of the disease. Am J Obstet Gynecol 194: 317-321
    • (2006) Am J Obstet Gynecol , vol.194 , pp. 317-321
    • Mignini, L.E.1
  • 4
    • 0037370337 scopus 로고    scopus 로고
    • Soluble VEGF receptor Flt1: The elusive preeclampsia factor discovered?
    • Luttun A and Carmeliet P (2003) Soluble VEGF receptor Flt1: the elusive preeclampsia factor discovered? J Clin Invest 111: 600-602
    • (2003) J Clin Invest , vol.111 , pp. 600-602
    • Luttun, A.1    Carmeliet, P.2
  • 5
    • 27744474462 scopus 로고
    • Uric acid clearance in normal pregnancy and pre-eclampsia
    • Schaffer NK et al. (1943) Uric acid clearance in normal pregnancy and pre-eclampsia. J Clin Invest 22: 201-206
    • (1943) J Clin Invest , vol.22 , pp. 201-206
    • Schaffer, N.K.1
  • 6
    • 50249144252 scopus 로고    scopus 로고
    • Groopman J (online 24 June 2006) The preeclampsia puzzle: making sense of a mysterious pregnancy disorder. The New Yorker [http://www.newyorker. com/archive/2006/07/24/060724fa_fact] (accessed 6 June 2008)
    • Groopman J (online 24 June 2006) The preeclampsia puzzle: making sense of a mysterious pregnancy disorder. The New Yorker [http://www.newyorker. com/archive/2006/07/24/060724fa_fact] (accessed 6 June 2008)
  • 7
    • 3442884269 scopus 로고    scopus 로고
    • Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia. Young Investigator Award
    • Chaiworapongsa T et al. (2004) Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia. Young Investigator Award. Am J Obstet Gynecol 190: 1541-1547
    • (2004) Am J Obstet Gynecol , vol.190 , pp. 1541-1547
    • Chaiworapongsa, T.1
  • 8
    • 4344564076 scopus 로고    scopus 로고
    • Maternal serum sFlt1 concentration is an early and reliable predictive marker of preeclampsia
    • Hertig A et al. (2004) Maternal serum sFlt1 concentration is an early and reliable predictive marker of preeclampsia. Clin Chem 50: 1702-1703
    • (2004) Clin Chem , vol.50 , pp. 1702-1703
    • Hertig, A.1
  • 9
    • 7044239727 scopus 로고    scopus 로고
    • Soluble vascular endothelial growth factor receptor-1 (sFlt-1) is increased throughout gestation in patients who have preeclampsia develop
    • McKeeman GC et al. (2004) Soluble vascular endothelial growth factor receptor-1 (sFlt-1) is increased throughout gestation in patients who have preeclampsia develop. Am J Obstet Gynecol 191: 1240-1246
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 1240-1246
    • McKeeman, G.C.1
  • 10
    • 23844510485 scopus 로고    scopus 로고
    • Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: Relationship to circulating placental growth factor
    • Shibata E et al. (2005) Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor. J Clin Endocrinol Metab 90: 4895-4903
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4895-4903
    • Shibata, E.1
  • 11
    • 10744232684 scopus 로고    scopus 로고
    • Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: Pathophysiological consequences
    • Tsatsaris V et al. (2003) Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: pathophysiological consequences. J Clin Endocrinol Metab 88: 5555-5563
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5555-5563
    • Tsatsaris, V.1
  • 12
    • 30344453927 scopus 로고    scopus 로고
    • Maternal serum-soluble vascular endothelial growth factor receptor-1 in early pregnancy ending in preeclampsia or intrauterine growth retardation
    • Wathen KA et al. (2006) Maternal serum-soluble vascular endothelial growth factor receptor-1 in early pregnancy ending in preeclampsia or intrauterine growth retardation. J Clin Endocrinol Metab 91: 180-184
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 180-184
    • Wathen, K.A.1
  • 13
    • 10744227199 scopus 로고    scopus 로고
    • Circulating angiogenic factors and the risk of preeclampsia
    • Levine RJ et al. (2004) Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 350: 672-683
    • (2004) N Engl J Med , vol.350 , pp. 672-683
    • Levine, R.J.1
  • 14
    • 41849108460 scopus 로고    scopus 로고
    • Hypertensive disorders of pregnancy: Future perspectives. A French point of view
    • Berkane N et al. (2008) Hypertensive disorders of pregnancy: future perspectives. A French point of view. Curr Opin Obstet Gynecol 20: 107-109
    • (2008) Curr Opin Obstet Gynecol , vol.20 , pp. 107-109
    • Berkane, N.1
  • 15
    • 0037631361 scopus 로고    scopus 로고
    • Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria
    • Sugimoto H et al. (2003) Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J Biol Chem 278: 12605-12608
    • (2003) J Biol Chem , vol.278 , pp. 12605-12608
    • Sugimoto, H.1
  • 16
    • 0037370325 scopus 로고    scopus 로고
    • Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
    • Eremina V et al. (2003) Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 111: 707-716
    • (2003) J Clin Invest , vol.111 , pp. 707-716
    • Eremina, V.1
  • 17
    • 0032589378 scopus 로고    scopus 로고
    • VEGF(165) mediates glomerular endothelial repair
    • Ostendorf T et al. (1999) VEGF(165) mediates glomerular endothelial repair. J Clin Invest 104: 913-923
    • (1999) J Clin Invest , vol.104 , pp. 913-923
    • Ostendorf, T.1
  • 18
    • 36048948982 scopus 로고    scopus 로고
    • Angiogenic factors in preeclampsia: So complex, so simple?
    • Berkane N et al. (2007) Angiogenic factors in preeclampsia: so complex, so simple? Nephrol Dial Transplant 22: 2753-2756
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 2753-2756
    • Berkane, N.1
  • 19
    • 16644387211 scopus 로고    scopus 로고
    • Vascular endothelial growth factor165 resolves glomerular inflammation and accelerates glomerular capillary repair in rat anti-glomerular basement membrane glomerulonephritis
    • Shimizu A et al. (2004) Vascular endothelial growth factor165 resolves glomerular inflammation and accelerates glomerular capillary repair in rat anti-glomerular basement membrane glomerulonephritis. J Am Soc Nephrol 15: 2655-2665
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2655-2665
    • Shimizu, A.1
  • 20
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar F et al. (2003) Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 21: 60-65
    • (2003) J Clin Oncol , vol.21 , pp. 60-65
    • Kabbinavar, F.1
  • 21
    • 40849130173 scopus 로고    scopus 로고
    • VEGF inhibition and renal thrombotic microangiopathy
    • Eremina V et al. (2008) VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 358: 1129-1136
    • (2008) N Engl J Med , vol.358 , pp. 1129-1136
    • Eremina, V.1
  • 22
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara N and Kerbel RS (2005) Angiogenesis as a therapeutic target. Nature 438: 967-974
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 23
    • 33748158307 scopus 로고    scopus 로고
    • Relationship between urinary albumin and serum soluble fms-like tyrosine kinase 1 (sFlt-1) in normal pregnancy
    • Yoshimatsu J et al. (2006) Relationship between urinary albumin and serum soluble fms-like tyrosine kinase 1 (sFlt-1) in normal pregnancy. Eur J Obstet Gynecol Reprod Biol 128: 204-208
    • (2006) Eur J Obstet Gynecol Reprod Biol , vol.128 , pp. 204-208
    • Yoshimatsu, J.1
  • 24
    • 0141652006 scopus 로고    scopus 로고
    • Glomerular endotheliosis in normal pregnancy and pre-eclampsia
    • Strevens H et al. (2003) Glomerular endotheliosis in normal pregnancy and pre-eclampsia. BJOG 110: 831-836
    • (2003) BJOG , vol.110 , pp. 831-836
    • Strevens, H.1
  • 25
    • 0033749607 scopus 로고    scopus 로고
    • Renal disease in women with severe preeclampsia or gestational proteinuria
    • Murakami S et al. (2000) Renal disease in women with severe preeclampsia or gestational proteinuria. Obstet Gynecol 96: 945-949
    • (2000) Obstet Gynecol , vol.96 , pp. 945-949
    • Murakami, S.1
  • 26
    • 33748421660 scopus 로고    scopus 로고
    • Soluble endoglin and other circulating antiangiogenic factors in preeclampsia
    • Levine RJ et al. (2006) Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med 355: 992-1005
    • (2006) N Engl J Med , vol.355 , pp. 992-1005
    • Levine, R.J.1
  • 27
    • 0022600773 scopus 로고
    • Urinary albumin excretion in pregnancy
    • Lopez-Espinoza I et al. (1986) Urinary albumin excretion in pregnancy. BJOG 93: 176-181
    • (1986) BJOG , vol.93 , pp. 176-181
    • Lopez-Espinoza, I.1
  • 28
    • 0026002071 scopus 로고
    • Urinary albumin excretion in normal pregnancy and pregnancy-induced hypertension
    • Misiani R et al. (1991) Urinary albumin excretion in normal pregnancy and pregnancy-induced hypertension. Nephron 59: 416-422
    • (1991) Nephron , vol.59 , pp. 416-422
    • Misiani, R.1
  • 29
    • 41149121011 scopus 로고    scopus 로고
    • Course of preeclamptic glomerular injury after delivery
    • Hladunewich MA et al. (2008) Course of preeclamptic glomerular injury after delivery. Am J Physiol Renal Physiol 294: F614-F620
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Hladunewich, M.A.1
  • 30
    • 0032918547 scopus 로고    scopus 로고
    • Microalbuminuria after pregnancy complicated by pre-eclampsia
    • Bar J et al. (1999) Microalbuminuria after pregnancy complicated by pre-eclampsia. Nephrol Dial Transplant 14: 1129-1132
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 1129-1132
    • Bar, J.1
  • 31
    • 0028790469 scopus 로고
    • Blood pressure and renal function seven years after pregnancy complicated by hypertension
    • Nisell H et al. (1995) Blood pressure and renal function seven years after pregnancy complicated by hypertension. BJOG 102: 876-881
    • (1995) BJOG , vol.102 , pp. 876-881
    • Nisell, H.1
  • 32
    • 33645450815 scopus 로고    scopus 로고
    • Adverse perinatal outcome and later kidney biopsy in the mother
    • Vikse BE et al. (2006) Adverse perinatal outcome and later kidney biopsy in the mother. J Am Soc Nephrol 17: 837-845
    • (2006) J Am Soc Nephrol , vol.17 , pp. 837-845
    • Vikse, B.E.1
  • 33
    • 0022977598 scopus 로고
    • Severe preeclampsia-eclampsia in young primigravid women: Subsequent pregnancy outcome and remote prognosis
    • Sibai BM et al. (1986) Severe preeclampsia-eclampsia in young primigravid women: subsequent pregnancy outcome and remote prognosis. Am J Obstet Gynecol 155: 1011-1016
    • (1986) Am J Obstet Gynecol , vol.155 , pp. 1011-1016
    • Sibai, B.M.1
  • 34
    • 1642419591 scopus 로고    scopus 로고
    • Manifestations of metabolic syndrome after hypertensive pregnancy
    • Pouta A et al. (2004) Manifestations of metabolic syndrome after hypertensive pregnancy. Hypertension 43: 825-831
    • (2004) Hypertension , vol.43 , pp. 825-831
    • Pouta, A.1
  • 35
    • 0035944725 scopus 로고    scopus 로고
    • Long term mortality of mothers and fathers after pre-eclampsia: Population based cohort study
    • Irgens HU et al. (2001) Long term mortality of mothers and fathers after pre-eclampsia: population based cohort study. BMJ 323: 1213-1217
    • (2001) BMJ , vol.323 , pp. 1213-1217
    • Irgens, H.U.1
  • 36
    • 27844535729 scopus 로고    scopus 로고
    • Cardiovascular health after maternal placental syndromes (CHAMPS): Population-based retrospective cohort study
    • Ray JG et al. (2005) Cardiovascular health after maternal placental syndromes (CHAMPS): population-based retrospective cohort study. Lancet 366: 1797-1803
    • (2005) Lancet , vol.366 , pp. 1797-1803
    • Ray, J.G.1
  • 37
    • 0037454357 scopus 로고    scopus 로고
    • Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: Results from cohort study
    • Wilson BJ et al. (2003) Hypertensive diseases of pregnancy and risk of hypertension and stroke in later life: results from cohort study. BMJ 326: 845
    • (2003) BMJ , vol.326 , pp. 845
    • Wilson, B.J.1
  • 38
    • 0035938977 scopus 로고    scopus 로고
    • Pregnancy complications and maternal risk of ischaemic heart disease: A retrospective cohort study of 129,290 births
    • Smith GC et al. (2001) Pregnancy complications and maternal risk of ischaemic heart disease: a retrospective cohort study of 129,290 births. Lancet 357: 2002-2006
    • (2001) Lancet , vol.357 , pp. 2002-2006
    • Smith, G.C.1
  • 39
    • 24744440146 scopus 로고    scopus 로고
    • Birth weight is inversely associated with incident coronary heart disease and stroke among individuals born in the 1950s: Findings from the Aberdeen Children of the 1950s prospective cohort study
    • Lawlor DA et al. (2005) Birth weight is inversely associated with incident coronary heart disease and stroke among individuals born in the 1950s: findings from the Aberdeen Children of the 1950s prospective cohort study. Circulation 112: 1414-1418
    • (2005) Circulation , vol.112 , pp. 1414-1418
    • Lawlor, D.A.1
  • 40
    • 0029893242 scopus 로고    scopus 로고
    • Treatment of hypertension in pregnant women
    • Sibai BM (1996) Treatment of hypertension in pregnant women. N Engl J Med 335: 257-265
    • (1996) N Engl J Med , vol.335 , pp. 257-265
    • Sibai, B.M.1
  • 41
    • 0035852492 scopus 로고    scopus 로고
    • Blood-pressure measurement and classification in pregnancy
    • Higgins JR and de Swiet M (2001) Blood-pressure measurement and classification in pregnancy. Lancet 357: 131-135
    • (2001) Lancet , vol.357 , pp. 131-135
    • Higgins, J.R.1    de Swiet, M.2
  • 42
    • 34347249118 scopus 로고    scopus 로고
    • Salahuddin S et al. (2007) Diagnostic utility of soluble fms-like tyrosine kinase 1 and soluble endoglin in hypertensive diseases of pregnancy. Am J Obstet Gynecol 197: 28.e1-28.e6
    • Salahuddin S et al. (2007) Diagnostic utility of soluble fms-like tyrosine kinase 1 and soluble endoglin in hypertensive diseases of pregnancy. Am J Obstet Gynecol 197: 28.e1-28.e6
  • 43
    • 0033609922 scopus 로고    scopus 로고
    • Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src
    • He H et al. (1999) Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src. J Biol Chem 274: 25130-25135
    • (1999) J Biol Chem , vol.274 , pp. 25130-25135
    • He, H.1
  • 44
    • 33744985816 scopus 로고    scopus 로고
    • Soluble endoglin contributes to the pathogenesis of preeclampsia
    • Venkatesha S et al. (2006) Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med 12: 642-649
    • (2006) Nat Med , vol.12 , pp. 642-649
    • Venkatesha, S.1
  • 45
    • 49849097449 scopus 로고    scopus 로고
    • Soluble endoglin levels during normotensive and hypertensive pregnancies
    • doi:10.1016/j.ejogrb.2007.09.007
    • Hertig A et al. (2007) Soluble endoglin levels during normotensive and hypertensive pregnancies. Eur J Obstet Gynecol Reprod Biol [doi:10.1016/j.ejogrb.2007.09.007]
    • (2007) Eur J Obstet Gynecol Reprod Biol
    • Hertig, A.1
  • 46
    • 33645884129 scopus 로고    scopus 로고
    • Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions?
    • Villar J et al. (2006) Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions? Am J Obstet Gynecol 194: 921-931
    • (2006) Am J Obstet Gynecol , vol.194 , pp. 921-931
    • Villar, J.1
  • 47
    • 0019404441 scopus 로고
    • Hypertension in pregnancy: Clinical-pathological correlations and remote prognosis
    • Fisher KA et al. (1981) Hypertension in pregnancy: clinical-pathological correlations and remote prognosis. Medicine (Baltimore) 60: 267-276
    • (1981) Medicine (Baltimore) , vol.60 , pp. 267-276
    • Fisher, K.A.1
  • 48
    • 0037050786 scopus 로고    scopus 로고
    • How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic review
    • Alfirevic Z et al. (2002) How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic review. Eur J Obstet Gynecol Reprod Biol 101: 6-14
    • (2002) Eur J Obstet Gynecol Reprod Biol , vol.101 , pp. 6-14
    • Alfirevic, Z.1
  • 50
    • 0032797872 scopus 로고    scopus 로고
    • Trophoblast deportation in human pregnancy - its relevance for pre-eclampsia
    • Johansen M et al. (1999) Trophoblast deportation in human pregnancy - its relevance for pre-eclampsia. Placenta 20: 531-539
    • (1999) Placenta , vol.20 , pp. 531-539
    • Johansen, M.1
  • 51
    • 34247574200 scopus 로고    scopus 로고
    • Systemic inflammatory priming in normal pregnancy and preeclampsia: The role of circulating syncytiotrophoblast microparticles
    • Germain SJ et al. (2007) Systemic inflammatory priming in normal pregnancy and preeclampsia: the role of circulating syncytiotrophoblast microparticles. J Immunol 178: 5949-5956
    • (2007) J Immunol , vol.178 , pp. 5949-5956
    • Germain, S.J.1
  • 52
    • 13244271259 scopus 로고    scopus 로고
    • Genetic thrombophilias and preeclampsia: A meta-analysis
    • Lin J and August P (2005) Genetic thrombophilias and preeclampsia: a meta-analysis. Obstet Gynecol 105: 182-192
    • (2005) Obstet Gynecol , vol.105 , pp. 182-192
    • Lin, J.1    August, P.2
  • 53
    • 40849105128 scopus 로고    scopus 로고
    • Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling
    • Zhou CC et al. (2008) Autoantibody from women with preeclampsia induces soluble Fms-like tyrosine kinase-1 production via angiotensin type 1 receptor and calcineurin/nuclear factor of activated T-cells signaling. Hypertension 51: 1010-1019
    • (2008) Hypertension , vol.51 , pp. 1010-1019
    • Zhou, C.C.1
  • 54
    • 0032924922 scopus 로고    scopus 로고
    • Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor
    • Wallukat G et al. (1999) Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor. J Clin Invest 103: 945-952
    • (1999) J Clin Invest , vol.103 , pp. 945-952
    • Wallukat, G.1
  • 55
    • 40849100423 scopus 로고    scopus 로고
    • Preeclampsia pathogenesis: "triple a rating"-autoantibodies and antiangiogenic factors
    • Karumanchi SA and Lindheimer MD (2008) Preeclampsia pathogenesis: "triple a rating"-autoantibodies and antiangiogenic factors. Hypertension 51: 991-992
    • (2008) Hypertension , vol.51 , pp. 991-992
    • Karumanchi, S.A.1    Lindheimer, M.D.2
  • 56
    • 20444375117 scopus 로고    scopus 로고
    • Steroid-responsive idiopathic glomerular capillary endotheliosis: Case report and literature review
    • Subramanya A et al. (2005) Steroid-responsive idiopathic glomerular capillary endotheliosis: case report and literature review. Am J Kidney Dis 45: 1090-1095
    • (2005) Am J Kidney Dis , vol.45 , pp. 1090-1095
    • Subramanya, A.1
  • 57
    • 0033057174 scopus 로고    scopus 로고
    • A prospective study on the occurrence of autoantibodies in low-risk pregnancies
    • Matthiesen LS et al. (1999) A prospective study on the occurrence of autoantibodies in low-risk pregnancies. Eur J Obstet Gynecol Reprod Biol 83: 21-26
    • (1999) Eur J Obstet Gynecol Reprod Biol , vol.83 , pp. 21-26
    • Matthiesen, L.S.1
  • 58
    • 45749098246 scopus 로고    scopus 로고
    • Deficiency in catechol-O- methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia
    • doi:10. 1038/nature06951
    • Kanasaki K et al. (2008) Deficiency in catechol-O- methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature [doi:10. 1038/nature06951]
    • (2008) Nature
    • Kanasaki, K.1
  • 59
    • 41849092309 scopus 로고    scopus 로고
    • Soluble fms-like tyrosine kinase associated with preeclampsia in pregnancy in systemic lupus erythematosus
    • Qazi U et al. (2008) Soluble fms-like tyrosine kinase associated with preeclampsia in pregnancy in systemic lupus erythematosus. J Rheumatol 35: 631-634
    • (2008) J Rheumatol , vol.35 , pp. 631-634
    • Qazi, U.1


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