The effect of lubrication on density distributions of roller compacted ribbons

International Journal of Pharmaceutics

Volumn 362, Issue 1-2, 2008, Pages 52-59

  Miguelez Moran A M ^a,b   Wu, C Y ^a   Seville, J P K ^c  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Agglomeration; Granulation; Lubrication; Ribbon; Roller compaction

Indexed keywords

ARTICLE; BULK DENSITY; DRUG GRANULATION; FLOW MEASUREMENT; FRICTION; LUBRICATION; POWDER; PRIORITY JOURNAL; TABLET COMPRESSION;

CELLULOSE; DRUG COMPOUNDING; EXCIPIENTS; LUBRICANTS; LUBRICATION; PHARMACEUTICAL PREPARATIONS; POWDERS; PRESSURE; STEARIC ACIDS; SURFACE PROPERTIES;

EID: 50249124761     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.06.009     Document Type: Article

References (24)

1. Bindhumadhavan G., Seville J.P.K., Adams M.J., Greenwood R.W., and Fitzpatrick S. Roll compaction of a pharmaceutical excipient: experimental validation of rolling theory for granular solids. Chem. Eng. Sci. 60 (2005) 3891-3897
2. Busies, H., 2006. PhD Dissertation, Dichteverteilung in Shülpen, Verlag Dr. Hut, München, Germany.
3. Guigon P., Simon O., Saleh K., Bindhumadhavan G., Adams M.J., and Seville J.P.K. Handbook of Powder Technology, vol. 11, Granulation (2007), Elsevier, Amsterdam
4. Guigon P., and Simon O. Interaction between feeding and compaction during lactose compaction in a laboratory roll press. KONA (2000) 131-138
5. Guigon P., and Simon O. Correlation between powder-packing properties and roll press compact heterogeneity. Powder Technol. 130 (2003) 41-48
6. Inghelbrecht S., and Remon J.P. Reducing dust and improving granule and tablet quality in the roller compaction process. Int. J. Pharm. 171 (1998) 195-206
7. Johanson, J.R., 1965. A rolling theory for granular solids, J. Appl. Mech., 32, Trans. ASME, 81, 842-848.
8. Kleinebudde P. Roll compaction/dry granulation: pharmaceutical applications. Eur. J. Pharm. Biopharm. 58 (2004) 317-326
9. Mansa, R.F., 2004. PhD Dissertation, Roller compaction of pharmaceutical excipients and prediction using intelligent software, University of Birmingham, UK.
10. Mansa R.F., Bridson R.H., Greenwood R.W., Barker H., and Seville J.P.K. Using intelligent software to predict the effects of formulation and processing parameters on roller compaction. Powder Technol. 181 (2008) 217-225
11. Michel, 1994. PhD Dissertation, Contribution a l'etude de l'agglomeration des pourdres en presse a rouleaux lises, Universite de Compiegne, France.
12. Miller. Handbook of Pharmaceutical Granulation Technology (1997), Marcel Dekker Inc., New York-Basel pp. 100-148, Chapter 6
13. Nystrom C., and Alderborn G. Bonding surface area and bonding mechanism: two important factors for understanding of powder compactability. The compaction behaviour of pharmaceutical materials. Drug Dev. Ind. Pharm. 19 (1993) 2143-2196
14. Perera, J., 2005. PhD Dissertation, Roll compaction of pharmaceutical excipients, University of Birmingham, UK.
15. Sheskey P.J., and Hendren J. The effects of roll compaction equipment variables, granulation technique, and HPMC polymer level on a controlled-release matrix model drug formulation. Pharm. Technol. 23 (1999) 90-106
16. Shlieout, G., Lammens, R.F., Kleinebudde, P., Bultmann, M., 2002, Dry granulation with a Gerteis 3-W-Polygran Roll compactor evaluation of different operation modes, Proc. 4th World Meeting ADRITELF/APGI/APV, Florence 8/11 April 2002.
17. Simon O., and Guigon P. Roll press design-influence of force feed systems on compaction. Powder Technol. 130 (2003) 257-264(8)
18. Tye C.K., Sun Ch.C., and Amidon G.E. Evaluation of the effects of tabletting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction. J. Pharm. Sci. 94 (2005) 465-472
19. Von Eggelkraut-Gottanka. Roller compaction and tabletting of St. John's wort plant dry extract using a gap width and force controlled roller compactor. I. Granulation and tabletting of eight different extract batches. Pharm. Dev. Technol. 7 (2002) 433-445
20. Weyenberg W., Vermeire A., Vandervoort J., Remon J.P., and Ludwig A. Effects of roller compaction settings on the preparation of bioadhesive granules on ocular minitablets. Eur. J. Pharm. Biopharm. 59 (2005) 527-536
21. Wikberg M., and Alderborn G. Compaction characteristics of granulated materials. IV. The effect of granule porosity on the fragmentation propensity and the compactibility of some granules. Int. J. Pharm. 69 (1991) 239-253
22. Wu C.Y., Best S.M., Bentham A.C., Hancock B.C., and Bonfield W. A simple predictive model for the tensile strength of binary tablets. Eur. J. Pharm. Sci. 25 (2005) 331-336
23. Wu C.Y., Best S.M., Bentham A.C., Hancock B.C., and Bonfield W. Predicting the tensile strength of multi-component pharmaceutical tablets. Pharm. Res. 23 (2006) 1898-1905
24. Zinchuk A.V., Mullarney M.P., and Hancock B.C. Simulation of roller compaction using a laboratory scale compaction simulator. Int. J. Pharm. 269 (2004) 403-415