Chemical stability and bioadhesive properties of an ester prodrug of Δ9-tetrahydrocannabinol in poly(ethylene oxide) matrices: Effect of formulation additives

International Journal of Pharmaceutics

Volumn 362, Issue 1-2, 2008, Pages 126-132

  Thumma, Sridhar ^a   Majumdar, Soumyajit ^a,b   ElSohly, Mahmoud A ^a,b,c   Gul, Waseem ^b,c   Repka, Michael A ^a,b  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c ElSohly Laboratories Incorporated   (United States)

Author keywords

Antioxidants; Bioadhesion; Poly(ethylene oxide); Prodrug; Stability; THC

Indexed keywords

ADHESIVE AGENT; ANTIOXIDANT; ASCORBIC ACID; BUTYLCRESOL; CARBOMER; CARBOPOL 971P; CITRIC ACID; DELTA9 TETRAHYDROCANNABINOL HEMIGLUTARATE; DRONABINOL; DRUG ADDITIVE; ESTER; GLUTARIC ACID DERIVATIVE; MACROGOL; PRODRUG; STABILIZING AGENT; UNCLASSIFIED DRUG;

ADHESION; ARTICLE; BIOADHESIVE PROPERTY; CONCENTRATION RESPONSE; DRUG DEGRADATION; DRUG MANUFACTURE; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; HOT MET FABRICATION; PRIORITY JOURNAL; ROOM TEMPERATURE;

ADHESIVENESS; ANIMALS; ANTIOXIDANTS; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; MOUTH MUCOSA; POLYETHYLENE GLYCOLS; PRODRUGS; SURFACE PROPERTIES; SWINE; TETRAHYDROCANNABINOL;

EID: 50249120699     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.06.025     Document Type: Article

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