The effect of complexation of Cu(II) with P6A peptide and its analogs on their thrombolytic activities

International Journal of Pharmaceutics

Volumn 362, Issue 1-2, 2008, Pages 81-87

  Yang, Mei ^a   Cui, Guohui ^b   Zhao, Ming ^b   Wang, Chao ^a   Wang, Lili ^b,c   Liu, Hu ^b,c   Peng, Shiqi ^a,b  

^a PEKING UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Cu(II) peptide complex; Self assembly; Thrombolytic activity

Indexed keywords

ALANYLARGINYLPROLYLALANYLLYSINE; ARGINYLPROLYLALANYLLYSINE; COPPER COMPLEX; GLYCYLARGINYLPROLYLALANYLLYSINE; PEPTIDE DERIVATIVE; PROLYLALANYLLYSINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOT LYSIS; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; DRUG EFFECT; ELECTROSPRAY MASS SPECTROMETRY; EUGLOBULIN LYSIS TEST; MALE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY; VASODILATATION; ZETA POTENTIAL;

ANIMALS; CIRCULAR DICHROISM; COPPER; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; FIBRINOLYTIC AGENTS; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; OLIGOPEPTIDES; PARTICLE SIZE; RATS; RATS, WISTAR; SERUM GLOBULINS; SPECTROPHOTOMETRY, ULTRAVIOLET; SURFACE PROPERTIES; SWINE; VASODILATION;

EID: 50249092102     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.06.014     Document Type: Article

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