Diffuse large B-cell lymphoma after transformation from low-grade follicular lymphoma: Morphological, immunohistochemical, and FISH analyses

Cancer Science

Volumn 99, Issue 9, 2008, Pages 1760-1768

  Maeshima, Akiko Miyagi ^a   Omatsu, Mutsuko ^a   Nomoto, Junko ^a   Maruyama, Dai ^a   Kim, Sung Won ^a   Watanabe, Takashi ^a   Kobayashi, Yukio ^a   Tobinai, Kensei ^a   Matsuno, Yoshihiro ^b  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD20 ANTIGEN; CD30 ANTIGEN; CD5 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; INTERFERON REGULATORY FACTOR 4; PROTEIN BCL 2; PROTEIN BCL 6; SYNDECAN 1;

ADULT; ANAPLASTIC CARCINOMA; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CANCER CLASSIFICATION; CANCER GRADING; CANCER MORPHOLOGY; CELL TYPE; CENTROBLASTIC CARCINOMA; CLINICAL ARTICLE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLICULAR LYMPHOMA; GENE FUSION; GENE TRANSLOCATION; GENETIC HETEROGENEITY; GERMINAL CENTER; HUMAN; HUMAN TISSUE; IMMUNOPATHOLOGY; IMMUNOPHENOTYPING; LARGE CELL LYMPHOMA; MALE; MALIGNANT TRANSFORMATION; PHENOTYPIC VARIATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

CELL TRANSFORMATION, NEOPLASTIC; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOMA, FOLLICULAR; LYMPHOMA, LARGE B-CELL, DIFFUSE; MALE; MIDDLE AGED;

EID: 50249083898     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00873.x     Document Type: Article

References (37)

1. A clinical evaluation of the International Lymphoma Study Group Classification of Non-Hodgkin's Lymphoma. The non-Hodgkin's Lymphoma Classification Project. Blood 1997; 89: 3909-18.
2. Horning SJ, Rosenberg SA. The natural history of initially untreated low-grade non-Hodgkin's lymphoma. N Eng J Med 1984; 311: 1471-5.
3. Gallagher CJ, Gregory WM, Jones AE et al. Follicular lymphoma: prognostic factors for response and survival. J Clin Oncol 1986; 4: 1470-80.
4. Harris NL, Ferry JA. Follicular lymphoma. In: Knowles DM, ed. Neoplastic Hematopathology, 2nd edn. Philadelphia, PA: Lippincott Williams & Wilkins, 2001; 823-53.
5. Alsabeh R, Medeiros LJ, Glackin C et al. Transformation of follicular lymphoma into CD30-large cell lymphoma with anaplastic cytologic features. Am J Surg Pathol 1997; 21: 528-36.
6. Yano T, Jaffe ES, Longo DJ et al. MYC rearrangements in histologically progressed follicular lymphomas. Blood 1992; 80: 758-67.
7. de Jong D, Voetdujk B, Bavestock G et al. Activation of the c-myc oncogene in a precursor B-cell blast crisis of follicular lymphoma, presenting as composite lymphoma. N Eng J Med 1998; 318: 1373.
8. Brauninger A, Hansmann ML, Strickler JG et al. Identification of common germinal-center B-cell precursors in two patients with both Hodgkin's disease and non-Hodgkin's lymphoma. N Eng J Med 1999; 340: 1239-47.
9. Marafioti T, Hummel M, Anagnostopoulos I et al. Classical Hodgkin's disease and follicular lymphoma originating from the same germinal center B cell. J Clin Oncol 1999; 17: 3804-9.
10. Sander CA, Yano T, Clark HM et al. p53 mutation is associated with progression in follicular lymphomas. Blood 1993; 82: 1994-2004.
11. Lo Coco F, Gaidano G, Louie DC et al. p53 mutations are associated with histologic transformation of follicular lymphoma. Blood 1993; 82: 2289-95.
12. Pinyol M, Cobo F, Bea S et al. p16 (INF4a) gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas. Blood 1998; 91: 2977-84.
13. Elenitoba-Johnson KS, Gascoyne RD, Lim MS et al. Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma. Blood 1998; 91: 4677-85.
14. Tilly H, Rossi A, Stamatoullas A et al. Prognostic value of chromosomal abnormalities in follicular lymphoma. Blood 1994; 84: 1043-9.
15. Alizadeh AA, Eisen MB, Davis RE et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000; 403: 503-11.
16. Rosenwald A, Wright G, Chan WC et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large B-cell lymphoma. N Eng J Med 2002; 346: 1937-47.
17. Hans SP, Weisenburger DD, Greiner TC et al. Conformation of molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. Blood 2004; 103: 275-82.
18. Davies AJ, Rosenwald A, Wright G et al. Transformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms. Br J Haematol 2007; 136: 286-93.
19. Godon A, Moreau A, Talmant P et al. Is t(14;18) (q32;q21) a constant finding in follicular lymphoma? An interphase FISH study on 63 patients. Leukemia 2003; 17: 255-9.
20. Biagi JJ, Suymour JF. Insights into the molecular pathogenesis of follicular lymphoma arising from analysis of geographic variation. Blood 2002; 99: 4265-75.
21. Sekiguchi N, Kobayashi Y, Yokota Y et al. Follicular lymphoma subgrouping by fluorescence in situ hybridization analysis. Cancer Sci 2005; 96: 77-82.
22. Leoncini L, Delsol G, Gascoyne RD et al. Aggressive B-cell lymphomas: A review based on the workshop of the XI meeting of the European association for haematopathology. Histopathology 2005; 46: 241-55.
23. Jaffe ES, Harris NL, Stein H et al. World Health Organization Classification of Tumors, Pathology and Genetics, Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press, 2001; 162-167: 171-4.
24. Dogan AMQ, Aiello A et al. Follicular lymphomas contain a clonally linked but phenotypically distinct neoplastic B-cell population in the interfollicular zone. Blood 1998; 91: 4708-14.
25. Nunez G, London L, Hockenbery D et al. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemoopietic cell lines. J Immunol 1990; 144: 3602-10.
26. Lai R, Arber DA, Chang KL et al. Frequency of bcl-2 expression in non-Hodtkin lymphoma: A study of 778 cases with comparison of marginal zone lymphoma and monocytoid B-cell hyperplasia. Mod Pathol 1998; 11: 864-9.
27. Falini B, Fizzotti M, Pileri S et al. Bcl-6 protein expression in normal and neoplastic lymphoid tissues. Ann Oncol 1997; 8: 101-4.
28. Peh SC, Shaminie J, Tai YC et al. The pattern and frequency of t(14;18) translocation and immunophenotype in Asian follicular lymphoma. Histopathology 2004; 45: 501-10.
29. Anagnostopoulos I, Dallenbach F, Stein H. Diffuse large cell lymphomas. In: Knowles DM, ed. Neoplastic Hematopathology, 2nd edn. Philadelphia, PA: Lippincott Williams & Wilkins, 2001; 860.
30. Mamane Y, Heylbroeck C, Genin P et al. Interferon regulatory factors: the next generation. Gene 1999; 237: 1-14.
31. Natkunam Y, Warnke RA, Montgomery K et al. Analysis of MUM1/IRF4 protein expression using tissue microarrays and immunohistochemistry. Mod Pathol 2001; 14: 686-94.
32. Falini B, Fizzotti M, Pucciarini A et al. A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. Blood 2000; 95: 2084-92.
33. Tsuboi K, Iida S, Inagaki H et al. MUM1/IRF4 expression as a frequent event in mature lymphoid malignancies. Leukemia 2000; 14: 449-56.
34. Piris M, Gatter KC, Mason DY. CD30 expression in follicular lymphoma. Histopathology 1991; 18: 25-9.
35. + diffuse large B-cell lymphoma: A clinicopathologic study of 109 patients. Blood 2002; 99: 815-21.
36. Manazza AD, Bonello L, Pagano M et al. Follicular origin of a subset of CD5 + diffuse large B-cell lymphomas. Am J Clin Pathol 2005; 124: 182-90.
37. Colomo L, Lopez-Guillermo A, Perales M et al. Clinical impact of the differentiation profile assessed by immunophenotyping in patients with diffuse large B-cell lymphoma. Blood 2003; 101: 78-84.