Frequency of bcl-2 expression in non-Hodgkin's lymphoma: A study of 778 cases with comparison of marginal zone lymphoma and monocytoid B-cell hyperplasia

Modern Pathology

Volumn 11, Issue 9, 1998, Pages 864-869

  Lai, R ^a   Arber, D A ^a   Chang, K L ^a   Wilson, C S ^a   Weiss, Lawrence M ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Bcl 2; Burkitt's lymphoma; Immunohistochemistry; Monocytoid B cell hyperplasia; Non Hodgkin's lymphoma

Indexed keywords

PROTEIN BCL 2;

ARTICLE; B LYMPHOCYTE ACTIVATION; BURKITT LYMPHOMA; DIFFERENTIAL DIAGNOSIS; GENE FREQUENCY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NONHODGKIN LYMPHOMA; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

B-LYMPHOCYTES; DIAGNOSIS, DIFFERENTIAL; EVALUATION STUDIES; HUMANS; HYPERPLASIA; IMMUNOENZYME TECHNIQUES; LYMPH NODES; LYMPHOMA; LYMPHOMA, NON-HODGKIN; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0031658927     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Tsujimoto Y, Finger LR, Yunis J, Nowell PC, Croce CM. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 1984; 226:1097-9.
2. Cleary ML, Sklar J. Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci U S A 1985;82:7439-43.
3. Korsmeyer SJ. bcl-2 initiates a new category of oncogenes: regulators of cell death. Blood 1992;80:879-86.
4. Kockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ. bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990;348:334-6.
5. Tsujimoto Y, Crossman J, Jaffe E, Croce CM. Involvement of the bcl-2 gene in human follicular lymphoma. Science 1985; 228:1440-3.
6. Ngan BY, Chen-Levy Z, Weiss LM, Warnke RA, Cleary M. Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. N Engl J Med 1988;318:1638-44.
7. Banks PM. When is a new diagnostic method established? [editorial]. Hum Pathol 1993;24:1153-4.
8. Utz GL, Swerdlow SH. Distinction of follicular hyperplasia from follicular lymphoma in B5-fixed tissues: comparison of MT2 and bcl-2 antibodies. Hum Pathol 1993;24:1155-8.
9. Gelb AB, Rouse R, Dorfman RF, Warnke RA. Detection of immunophenotypic abnormalities in paraffin-embedded B-lineage non-Hodgkin's lymphomas. Am J Clin Pathol 1994; 102:825-34.
10. Said J, Pinkus GS, Lones MA, Preston M, Shintaku IP. Expression of bcl-2 oncogene protein in malignant lymphomas, including Hodgkin's disease and non-Hodgkin's lymphomas of T-cell phenotype. Appl Immunohistochem 1993; 1:108-14.
11. Gaulard P, d'Agay M-F, Peuchmaur M, Brousse N, Gisselbrecht C, Solal-Celigny P, et al. Expression of the bcl-2 gene product in follicular lymphoma. Am J Pathol 1992;140:1089-95.
12. Wang T, Lasota J, Hanau CA, Miettinen M. bcl-2 oncoprotein is widespread in lymphoid tissue and lymphomas but its differential expression in benign versus malignant follicles and monocytoid B-cell proliferations is of diagnostic value. APMIS 1995;103:655-62.
13. Sheibani K, Fritz R, Winberg C, Burke JS, Rappaport H. Monocytoid cells in reactive follicular hyperplasia with and without histiocytic reaction: an immunohistochemical study of 21 cases including suspected cases of toxoplasmic lymphadenitis. Am J Clin Pathol 1984;81:453-8.
14. Sohn CC, Sheibani K, Winberg CD, Rappaport H. Monocytoid B lymphocytes: their relation to the patterns of the acquired immunodeficiency syndrome (AIDS) and AIDS-related lymphadenopathy. Hum Pathol 1985;16:979-85.
15. Chan JKC, Tsang WYW. Reactive lymphadenopathies. In: Weiss LM, editor. Pathology of lymph nodes. New York: Churchill Livingstone; 1996. p. 81-167.
16. Hernandez AM, Nathwani BN, Nguyen D, Shibata D, Chuan W, Nichols P, et al. Nodal benign and malignant monocytoid B cells with and without follicular lymphomas: a comparative study of follicular colonization, light chain restriction, bcl-2, and t(14;18) in 39 cases. Hum Pathol 1995;26:625-32.
17. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JK, Cleary ML, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 1994;84:1361-92.
18. Brynes RK, Almaguer PD, Leathery KE, McCourty A, Arber DA, Medeiros LJ, et al. Numerical cytogenetic abnormalities of chromosomes 3, 7, and 12 in marginal zone B-cell lymphomas. Mod Pathol 1996;9:995-1000.
19. Sole F, Woessner S, Florensa L, Espinet B, Mollejo M, Martin P, et al. Frequent involvement of chromosomes 1, 3, 7, and 8 in splenic marginal zone B-cell lymphoma. Br J Haematol 1997;98:446-9.
20. Lima M, Teixeira MA, Queiros ML, Santos AHR, Justica B. bcl-2 (p26) oncoprotein in splenic lymphoma with villous lymphocytes: a comparative study with other chronic B-cell disorder. Am J Hematol 1997;56:122-5.
21. Yano T, van Krieken J, Magrath I, Longo DL, Jaffe E, Raffeld M. Histogenetic correlations between subcategories of small noncleaved cell lymphomas. Blood 1992;79:1282-90.
22. Weiss LM, Warnke RA, Sklar J, Cleary ML. Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas. N Engl J Med 1987;317:1185-9.
23. Offit K, Koduru PR, Hollis R, Filippa D, Jhanwar SC, Clarkson BC, et al. 18q21 rearrangement in diffuse large cell lymphoma: incidence and clinical significance. Br J Haematol 1989;72:178-83.