Angiogenesis in liver cirrhosis and hepatocellular carcinoma

Indian Journal of Pathology and Microbiology

Volumn 51, Issue 3, 2008, Pages 323-328

  Amarapurkar, Anjali ^a,c   Vibhav, ^a   Kim, V ^b  

^a BYL NAIR CHARITABLE HOSPITAL   (India)

^b POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^c Ameya Society   (India)

Author keywords

Angiogenesis; CD 34; Cirrhosis; Hepatocellular carcinoma; Liver

Indexed keywords

CD34 ANTIBODY;

ANGIOGENESIS; ARTICLE; AUTOPSY; CANCER CLASSIFICATION; CANCER GRADING; ENDOTHELIUM CELL; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER METASTASIS; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD34; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; SEVERITY OF ILLNESS INDEX;

EID: 50149116224     PISSN: 03774929     EISSN: None     Source Type: Journal    
DOI: 10.4103/0377-4929.42504     Document Type: Article

References (27)

1. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-57.
2. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995;1:27-31.
3. Arnold F, West DC. Angiogenesis in wound healing. Pharmacol Therap 1991;52:407-22.
4. Carmeliet P. Angiogenesis in health and disease. Nat Med 2003;9:653-60.
5. Wu MC. Clinical research advances in primary liver cancer. World J Gastroenterol 1998;4:471-4.
6. Messerini L, Novelli L, Comin CE. Microvessel density and clinicopathological characteristics in hepatitis C virus and hepatitis B virus related hepatocellular carcinoma. J Clin Pathol 2004;57:867-71.
7. Medina J, Arroyo AG, Madrid FS, Otero RM. Angiogenesis in chronic inflammatory liver disease. Hepatology 2004;39:1185-95.
8. Couvelard A, Scoazec JY, Feldmann G. Expression of cell-cell and cell-matrix adhesion proteins by sinusoidal endothelial cells in the normal and cirrhotic human liver. Am J Pathol 1993;143:738-52.
9. Park YN, Yang CP, Fernandez GJ, Cubukcu O, Thung SN, Theise ND. Neoangiogenesis and sinusoidal "capillarization" in dysplastic nodules of the liver. Am J Surg Pathol 1998;22:656-62.
10. Takeda A, Stoeltzing O, Ahmad SA, Reinmuth N, Liu W, Parikh A, et al. Role of angiogenesis in the development and growth of liver metastasis. Ann Surg Oncol 2002;9:610-6.
11. Ramani P, Bradley NJ, Fletcher CD. QBEND/10, a new monoclonal antibody to endothelium: Assessment of its diagnostic utility in paraffin sections. Histopathology 1990;17:237-42.
12. Pusztaszeri M, Chaubert P, Bosman FT, Seelentag W. Immunohistochemical expression expression of endothelial markers CD31, CD34, von-Willebrand factor and Fli-1 in normal human tissues. J Histochem Cytochem 2006;54:385-95.
13. Scoazec LY, Delautier D, Feldman G. Expression of cell-cell and cell-matrix adhesion proteins by sinusoidal endothelial cells in the normal and cirrhotic liver. Hepatology 1991;14:189A.
14. Xu GF, Wang XY, Ge GL, Li PT, Jia X, Tian DL, et al. Dynamic changes of capillarization and peri-sinusoid fibrosis in alcoholic liver diseases. World J Gastroenterol 2004;10:238-43.
15. Ohmori S, Shiraki K, Sugimoto K, Sakai T, Fujikawa K, Wagayama H, et al. High expression of CD34 positive sinusoidal endothelial cells is a risk factor for hepatocellular carcinoma in patients with HCV-associated chronic liver diseases. Hum Pathol 2001;32:1363-70.
16. Bosch FX, Ribes J, Borras J. Epidemiology of primary liver cancer. Semin Liver Dis 1999;19:271-85.
17. Vertemati M, Minola E, Goffredi M, Sabatella G, Gambacorta M, Vizzotto L. Computerized morphometry of the cirrhotic liver: Comparative analysis in primary biliary cirrhosis, alcoholic cirrhosis and posthepatitic cirrhosis. Microsc Res Tech 2004;65:113-21.
18. Semela D, Dufour JF. Angiogenesis and hepatocellular carcinoma. J Hepatol 2004;41:864-80.
19. De Boer WB, Segal A, Frost FA, Sterrett GF. Can CD34 discriminate between benign and malignant hepatocytic lesions in fine-needle aspirates and thin core biopsies? Cancer 2000;90:273-8.
20. Cui S, Hano H, Sakata A, Harada T, Liu T, Takai S, et al. Enhanced CD34 expression of sinusoid-like vascular endothelial cells in hepatocellular carcinoma. Pathol Int 1996;46:751-6.
21. Maeda T, Adachi E, Kajiyama K, Takenaka K, Honda H, Sugimachi K, et al. CD34 expression in endothelial cells of small hepatocellular carcinoma: Its correlation with tumour progression and angiographic findings. J Gastroenterol Hepatol 1995;10:650-4.
22. Kimura H, Nakajima T, Kagawa K, Deguchi T, Kakusui M, Katagishi T, et al. Angiogenesis in hepatocellular carcinoma as evaluated by CD34 immunohistochemistry. Liver 1998;18:14-9.
23. Terayama N, Terada T, Nakanuma Y. An immunohistochemical study of tumour vessels in metastatic liver cancers and the surrounding liver tissue. Histopathology 1996;29:37-43.
24. Vermeulen PB, Colpaert C, Salgado R, Royers R, Hellemans H, Heuvel EV, et al. Liver metastases from colorectal adenocarcinomas grow in three patterns with different angiogenesis and desmoplasia. J Pathol 2001;195: 336-42.
25. Hillen HR, Hak LE, Achjanie SR, Arends JW. Microvessel density in unknown primary tumors. Int J Cancer 1997;74:81-5.
26. Peeters CF, Westphal JR, De Waal RM, Ruiter DJ, Wobbes T, Ruers TJ. Vascular density in colorectal liver metastases increases after removal of the primary tumor in human cancer patients. Int J Cancer 2004;112:554-9.
27. Deli G, Jin CH, Mu R, Yang S, Liang Y, Chen D, et al. Immunohistochemical assessment of angiogenesis in hepatocellular carcinoma and surrounding cirrhotic liver tissues. World J Gastroenterol 2005;11:960-3.