Role of the malate-aspartate shuttle on the metabolic response to myocardial ischemia

Journal of Theoretical Biology

Volumn 254, Issue 2, 2008, Pages 466-475

  Lu, Ming ^a,c   Zhou, Lufang ^a,c   Stanley, William C ^b,c,d   Cabrera, Marco E ^a,b,c   Saidel, Gerald M ^a,c   Yu, Xin ^a,c  

^a Case Western Reserve University   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Malate aspartate shuttle; Mathematical modeling; Metabolic compartmentation; Myocardial ischemia

Indexed keywords

ASPARTIC ACID; GLYCOGEN; LACTIC ACID; MALIC ACID;

BIOCHEMISTRY; CARDIOVASCULAR DISEASE; CYTOLOGY; MEMBRANE; METABOLISM; MITOCHONDRION; MODELING; NUMERICAL MODEL; PREDICTION;

ARTICLE; BLOOD FLOW; COMPARTMENT MODEL; CYTOSOL; GLYCOLYSIS; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; HEART MUSCLE METABOLISM; IN VIVO STUDY; METABOLIC ACTIVATION; METABOLIC REGULATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEADY STATE;

ANIMALS; ASPARTIC ACID; COMPUTER SIMULATION; CORONARY CIRCULATION; CYTOSOL; ENERGY METABOLISM; GLYCOLYSIS; HUMANS; INTRACELLULAR MEMBRANES; LACTATES; MALATES; MITOCHONDRIA, HEART; MODELS, BIOLOGICAL; MYOCARDIAL ISCHEMIA; MYOCARDIUM;

EID: 50149111942     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2008.05.033     Document Type: Article

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