Involvement of neuromedin S in the oxytocin release response to suckling stimulus

Biochemical and Biophysical Research Communications

Volumn 375, Issue 1, 2008, Pages 49-53

  Sakamoto, Takumi ^a   Mori, Kenji ^b   Miyazato, Mikiya ^b   Kangawa, Kenji ^b   Sameshima, Hiroshi ^a   Nakahara, Keiko ^a   Murakami, Noboru ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Milk ejection; Neuromedin S; Oxytocin; Suckling

Indexed keywords

NEUROMEDIN S; NEUROPEPTIDE; OXYTOCIN; OXYTOCIN RECEPTOR; PROTEIN C FOS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; LACTATION; NONHUMAN; OXYTOCIN RELEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SUCKLING; SUPRAOPTIC NUCLEUS; THALAMUS MIDLINE NUCLEUS;

ANIMALS; ANIMALS, SUCKLING; FEMALE; MILK EJECTION; NEUROPEPTIDES; OXYTOCIN; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; SUPRAOPTIC NUCLEUS;

RATTUS;

EID: 50149090232     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.07.124     Document Type: Article

References (28)

1. Fujii R., Hosoya M., Fukusumi S., Kawamata Y., Habata Y., Hinuma S., Onda H., Nishimura O., and Fujino M. Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3. J. Biol. Chem. 275 (2000) 21068-21074
2. Hedrick J.A., Morse K., Shan L., Qiao X., Pang L., Wang S., Laz T., Gustafson E.L., Bayne M., and Monsma Jr. F.J. Identification of a human gastrointestinal tract and immune system receptor for the peptide neuromedin U. Mol. Pharmacol. 58 (2000) 870-875
3. Hosoya M., Moriya T., Kawamata Y., Ohkubo S., Fujii R., Matsui H., Shintani Y., Fukusumi S., Habata Y., Hinuma S., Onda H., Nishimura O., and Fujino M. Identification and functional characterization of a novel subtype of neuromedin U receptor. J. Biol. Chem. 275 (2000) 29528-29532
4. Kojima M., Haruno R., Nakazato M., Date Y., Murakami N., Hanada R., Matsuo H., and Kangawa K. Purification and identification of neuromedin U as an endogenous ligand for an orphan receptor GPR66 (FM3). Biochem. Biophys. Res. Commun. 276 (2000) 435-438
5. Howard A.D., Wang R., Pong S.S., Mellin T.N., Strack A., Guan X.M., Zeng Z., Williams Jr. D.L., Feighner S.D., Nunes C.N., Murphy B., Stair J.N., Yu H., Jiang Q., Clements M.K., Tan C.P., McKee K.K., Hreniuk D.L., McDonald T.P., Lynch K.R., Evans J.F., Austin C.P., Caskey C.T., Van der Ploeg L.H., and Liu Q. Identification of receptors for neuromedin U and its role in feeding. Nature 406 (2000) 70-74
6. Raddatz R., Wilson A.E., Artymyshyn R., Bonini J.A., Borowsky B., Boteju L.W., Zhou S., Kouranova E.V., Nagorny R., Guevarra M.S., Dai M., Lerman G.S., Vaysse P.J., Branchek T.A., Gerald C., Forray C., and Adham N. Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system. J. Biol. Chem. 275 (2000) 32452-32459
7. Mori K., Miyazato M., Ida T., Murakami N., Serino R., Ueta Y., Kojima M., and Kangawa K. Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J. 24 (2005) 325-335
8. Miyazato M., Mori K., Ida T., Kojima M., Murakami N., and Kangawa K. Identification and functional analysis of a novel ligand for G protein-coupled receptor, neuromedin S. Regul. Pept. 145 (2008) 37-41
9. Mori K., Miyazato M., and Kangawa K. Neuromedin S: discovery and functions. Results Probl. Cell Differ. (2008) 24
10. Ida T., Mori K., Miyazato M., Egi Y., Abe S., Nakahara K., Nishihara M., Kangawa K., and Murakami N. Neuromedin S is a novel anorexigenic hormone. Endocrinology 146 (2005) 4217-4223
11. Sakamoto T., Mori K., Nakahara K., Miyazato M., Kangawa K., Sameshima H., and Murakami N. Neuromedin S exerts an antidiuretic action in rats. Biochem. Biophys. Res. Commun. 361 (2007) 457-461
12. Graham E.S., Turnbull Y., Fotheringham P., Nilaweera K., Mercer J.G., Morgan P.J., and Barrett P. Neuromedin U and neuromedin U receptor-2 expression in the mouse and rat hypothalamus: effects of nutritional status. J. Neurochem. 87 (2003) 1165-1173
13. Guan X.M., Yu H., Jiang Q., Van Der Ploeg L.H., and Liu Q. Distribution of neuromedin U receptor subtype 2 mRNA in the rat brain. Brain Res. Gene Expr. Patterns 1 (2001) 1-4
14. Qiu D.L., Chu C.P., Tsukino H., Shirasaka T., Nakao H., Kato K., Kunitake T., Katoh T., and Kannan H. Neuromedin U receptor-2 mRNA and HCN channels mRNA expression in NMU-sensitive neurons in rat hypothalamic paraventricular nucleus. Neurosci. Lett. 374 (2005) 69-72
15. Nishimori K., Young L.J., Guo Q., Wang Z., Insel T.R., and Matzuk M.M. Oxytocin is required for nursing but is not essential for parturition or reproductive behavior. Proc. Natl. Acad. Sci. USA 93 (1996) 11699-11704
16. Ida T., Nakahara K., Katayama T., Murakami N., and Nakazato M. Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats. Brain Res. 821 (1999) 526-529
17. Hosoda H., Kojima M., Matsuo H., and Kangawa K. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem. Biophys. Res. Commun. 279 (2000) 909-913
18. Ozaki Y., Onaka T., Nakazato M., Saito J., Kanemoto K., Matsumoto T., and Ueta Y. Centrally administered neuromedin U activates neurosecretion and induction of cFos messenger ribonucleic acid in the paraventricular and supraoptic nuclei of rat. Endocrinology 143 (2002) 4320-4329
19. Hanada R., Nakazato M., Murakami N., Sakihara S., Yoshimatsu H., Toshinai K., Hanada T., Suda T., Kangawa K., Matsukura S., and Sakata T. A role for neuromedin U in stress response. Biochem. Biophys. Res. Commun. 289 (2001) 225-228
20. Lincoln D.W., and Wakerley J.B. Electrophysiological evidence for the activation of supraoptic neurones during the release of oxytocin. J. Physiol. 242 (1974) 533-554
21. Meyer C., Freund-Mercier M.J., Guerne Y., and Richard P. Relationship between oxytocin release and amplitude of oxytocin cell neurosecretory bursts during suckling in the rat. J. Endocrinol. 114 (1987) 263-270
22. Bealer S.L., and Crowley W.R. Noradrenergic control of central oxytocin release during lactation in rats. Am. J. Physiol. 274 (1998) E453-E458
23. Israel J.M., Le Masson G., Theodosis D.T., and Poulain D.A. Glutamatergic input governs periodicity and synchronization of bursting activity in oxytocin neurons in hypothalamic organotypic cultures. Eur. J. Neurosci. 17 (2003) 2619-2629
24. Neumann I., Koehler E., Landgraf R., and Summy-Long J. An oxytocin receptor antagonist infused into the supraoptic nucleus attenuates intranuclear and peripheral release of oxytocin during suckling in conscious rats. Endocrinology 134 (1994) 141-148
25. de Kock C.P., Wierda K.D., Bosman L.W., Min R., Koksma J.J., Mansvelder H.D., Verhage M., and Brussaard A.B. Somatodendritic secretion in oxytocin neurons is upregulated during the female reproductive cycle. J. Neurosci. 23 (2003) 2726-2734
26. Wang Y.F., and Hatton G.I. Dominant role of betagamma subunits of G-proteins in oxytocin-evoked burst firing. J. Neurosci. 27 (2007) 1902-1912
27. Brighton P.J., Szekeres P.G., Wise A., and Willars G.B. Signaling and ligand binding by recombinant neuromedin U receptors: evidence for dual coupling to Galphaq/11 and Galphai and an irreversible ligand-receptor interaction. Mol. Pharmacol. 66 (2004) 1544-1556
28. Nakahara K., Kojima M., Hanada R., Egi Y., Ida T., Miyazato M., Kangawa K., and Murakami N. Neuromedin U is involved in nociceptive reflexes and adaptation to environmental stimuli in mice. Biochem. Biophys. Res. Commun. 323 (2004) 615-620