Tonic activation of GLUK5 kainate receptors decreases neuroblast migration in whole-mounts of the subventricular zone

Journal of Physiology

Volumn 586, Issue 16, 2008, Pages 3783-3793

  Platel, Jean Claude ^a   Heintz, Tristan ^a   Young, Stephanie ^a   Gordon, Valerie ^a   Bordey, Angélique ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; BICUCULLINE; CALCIUM ION; GREEN FLUORESCENT PROTEIN; KAINIC ACID RECEPTOR; KAINIC ACID RECEPTOR ANTAGONIST; MESSENGER RNA; METABOTROPIC RECEPTOR 5; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; GLUR5 KAINATE RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; DOUBLECORTIN; NS 3763; UB 302; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL MIGRATION; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; LATERAL BRAIN VENTRICLE; MOUSE; NEUROBLAST; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ADULT; ADULT STEM CELL; ANIMAL; BRAIN VENTRICLE; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; HUMAN; METABOLISM; NERVE CELL; PHYSIOLOGY; CALCIUM TRANSPORT; PATCH CLAMP TECHNIQUE; PERINATAL PERIOD; SUBVENTRICULAR ZONE; TRANSGENIC MOUSE;

ADULT; ADULT STEM CELLS; ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CEREBRAL VENTRICLES; HUMANS; MICE; MICE, INBRED C57BL; NEURONS; NEUROTRANSMITTER AGENTS; RECEPTORS, KAINIC ACID;

EID: 50049101053     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2008.155879     Document Type: Article

References (35)

1. Alt A, Weiss B, Ogden AM, Knauss JL, Oler J, Ho K, Large TH & Bleakman D (2004). Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro. Neuropharmacology 46, 793-806.
2. Bernard A & Khrestchatisky M (1994). Assessing the extent of RNA editing in the TMII regions of GluR5 and GluR6 kainate receptors during rat brain development. J Neurochem 62, 2057-2060.
3. Bolteus AJ & Bordey A (2004). GABA release and uptake regulate neuronal precursor migration in the postnatal subventricular zone. J Neurosci 24, 7623-7631.
4. Bordey A (2006). Adult neurogenesis: Basic concepts of signaling. Cell Cycle 5, 722-728.
5. Bordey A (2007). Enigmatic GABAergic networks in adult neurogenic zones. Brain Res Brain Res Rev 53, 124-134.
6. Christensen JK, Paternain AV, Selak S, Ahring PK & Lerma J (2004a). A mosaic of functional kainate receptors in hippocampal interneurons. J Neurosci 24, 8986-8993.
7. Christensen JK, Varming T, Ahring PK, Jorgensen TD & Nielsen EO (2004b). In vitro characterization of 5-carboxyl-2,4-di-benzamidobenzoic acid (NS3763), a noncompetitive antagonist of GLUK5 receptors. J Pharmacol Exp Ther 309, 1003-1010.
8. Conn PJ & Pin JP (1997). Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol 37, 205-237.
9. Davila NG, Houpt TA & Trombley PQ (2007). Expression and function of kainate receptors in the rat olfactory bulb. Synapse 61, 320-334.
10. Di Giorgi Gerevini V, Caruso A, Cappuccio I, Ricci Vitiani L, Romeo S, Della Rocca C, Gradini R, Melchiorri D & Nicoletti F (2004). The mGlu5 metabotropic glutamate receptor is expressed in zones of active neurogenesis of the embryonic and postnatal brain. Brain Res Dev Brain Res 150, 17-22.
11. Di Giorgi-Gerevini V, Melchiorri D, Battaglia G, Ricci-Vitiani L, Ciceroni C, Busceti CL, Biagioni F, Iacovelli L, Canudas AM, Parati E, De Maria R & Nicoletti F (2005). Endogenous activation of metabotropic glutamate receptors supports the proliferation and survival of neural progenitor cells. Cell Death Differ 12, 1124-1133.
12. Dolman NP, Troop HM, More JC, Alt A, Knauss JL, Nistico R, Jack S, Morley RM, Bortolotto ZA, Roberts PJ, Bleakman D, Collingridge GL & Jane DE (2005). Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors. J Med Chem 48, 7867-7881.
13. 3H]ATPA: A high affinity ligand for GluR5 kainate receptors. Neuropharmacology 38, 1811-1817.
14. Howe JR (1996). Homomeric and heteromeric ion channels formed from the kainate-type subunits GluR6 and KA2 have very small, but different, unitary conductances. J Neurophysiol 76, 510-519.
15. 2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: Diversity by RNA editing. Neuron 10, 491-500.
16. Lauri SE, Vesikansa A, Segerstrale M, Collingridge GL, Isaac JT & Taira T (2006). Functional maturation of CA1 synapses involves activity-dependent loss of tonic kainate receptor-mediated inhibition of glutamate release. Neuron 50, 415-429.
17. Lerma J, Paternain AV, Rodriguez-Moreno A & López-Garcia JC (2001). Molecular physiology of kainate receptors. Physiol Rev 81, 971-998.
18. Liu X, Bolteus AJ, Balkin DM, Henschel O & Bordey A (2006). GFAP-expressing cells in the postnatal subventricular zone display a unique glial phenotype intermediate between radial glia and astrocytes. Glia 54, 394-410.
19. Liu X, Wang Q, Haydar TF & Bordey A (2005). Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors. Nat Neurosci 8, 1179-1187.
20. Lledo PM, Alonso M & Grubb MS (2006). Adult neurogenesis and functional plasticity in neuronal circuits. Nat Rev Neurosci 7, 179-193.
21. Merkle FT, Mirzadeh Z & Alvarez-Buylla A (2007). Mosaic organization of neural stem cells in the adult brain. Science 317, 381-384.
22. More JC, Nistico R, Dolman NP, Clarke VR, Alt AJ, Ogden AM, Buelens FP, Troop HM, Kelland EE, Pilato F, Bleakman D, Bortolotto ZA, Collingridge GL & Jane DE (2004). Characterisation of UBP296: A novel, potent and selective kainate receptor antagonist. Neuropharmacology 47, 46-64.
23. Nacher J, Crespo C & McEwen BS (2001). Doublecortin expression in the adult rat telencephalon. Eur J Neurosci 14, 629-644.
24. Nam SC, Kim Y, Dryanovski D, Walker A, Goings G, Woolfrey K, Kang SS, Chu C, Chenn A, Erdelyi F, Szabo G, Hockberger P & Szele FG (2007). Dynamic features of postnatal subventricular zone cell motility: A two-photon time-lapse study. J Comp Neurol 505, 190-208.
25. Paternain AV, Herrera MT, Nieto MA & Lerma J (2000). GluR5 and GluR6 kainate receptor subunits coexist in hippocampal neurons and coassemble to form functional receptors. J Neurosci 20, 196-205.
26. Pinheiro P & Mulle C (2006). Kainate receptors. Cell Tissue Res 326, 457-482.
27. Platel JC, Dave KA & Bordey A (2008). Control of neuroblast production and migration by converging GABA and glutamate signals in the postnatal forebrain. J Physiol 586, 3739-3743.
28. Platel JC, Dupuis A, Boisseau S, Villaz M, Albrieux M & Brocard J (2007a). Synchrony of spontaneous calcium activity in mouse neocortex before synaptogenesis. Eur J Neurosci 25, 920-928.
29. Platel JC, Lacar B & Bordey A (2007b). GABA and glutamate signaling: homeostatic control of adult forebrain neurogenesis. J Mol Histol 38, 602-610.
30. Salt TE, Binns KE, Turner JP, Gasparini F & Kuhn R (1999). Antagonism of the mGlu5 agonist 2-chloro-5-hydroxyphenylglycine by the novel selective mGlu5 antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) in the thalamus. Br J Pharmacol 127, 1057-1059.
31. Siegel SJ, Janssen WG, Tullai JW, Rogers SW, Moran T, Heinemann SF & Morrison JH (1995). Distribution of the excitatory amino acid receptor subunits GluR2(4) in monkey hippocampus and colocalization with subunits GluR5-7 and NMDAR1. J Neurosci 15, 2707-2719.
32. Swanson GT, Feldmeyer D, Kaneda M & Cull-Candy SG (1996). Effect of RNA editing and subunit co-assembly single-channel properties of recombinant kainate receptors. J Physiol 492, 129-142.
33. Vesikansa A, Sallert M, Taira T & Lauri SE (2007). Activation of kainate receptors controls the number of functional glutamatergic synapses in the area CA1 of rat hippocampus. J Physiol 583, 145-157.
34. Wang DD, Krueger DD & Bordey A (2003 a). Biophysical properties and ionic signature of neuronal progenitors of the postnatal subventricular zone in situ. J Neurophysiol 90, 2291-2302.
35. Wang DD, Krueger DD & Bordey A (2003b). GABA depolarizes neuronal progenitors of the postnatal subventricular zone via GABA A receptor activation. J Physiol 550, 785-800.