The mGlu5 metabotropic glutamate receptor is expressed in zones of active neurogenesis of the embryonic and postnatal brain

Developmental Brain Research

Volumn 150, Issue 1, 2004, Pages 17-22

  Di Giorgi Gerevini, V D ^a   Caruso, A ^a   Cappuccio, I ^a   Ricci Vitiani, L ^b   Romeo, S ^a   Della Rocca, C ^a   Gradini, R ^a,c   Melchiorri, D ^a   Nicoletti, F ^a,c  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c IRCCS NEUROMED   (Italy)

Author keywords

Cell proliferation; Development; External granular layer; Prenatal expression; Subventricular zone

Indexed keywords

BROXURIDINE; ISOPROTEIN; MESSENGER RNA; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 4; METABOTROPIC RECEPTOR 5;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN NERVE CELL; BRAIN REGION; BRAIN VENTRICLE; CELL PROLIFERATION; CEREBELLUM CORTEX; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; IMMUNOHISTOCHEMISTRY; MALE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STAINING; STEM CELL;

ANIMALS; ANIMALS, NEWBORN; BRAIN; BROMODEOXYURIDINE; CELL DIFFERENTIATION; CELL DIVISION; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUTAMIC ACID; MALE; NEURONAL PLASTICITY; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; RNA, MESSENGER; STEM CELLS;

EID: 4143089114     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devbrainres.2004.02.003     Document Type: Article

References (38)

1. Bear M.F, Dudek S.M. Stimulation of phosphoinositide turnover by excitatory amino acids. Ann. N. Y. Acad. Sci. 627:1991;42-56
2. Bear M.F, Rittenhouse C.D. Molecular basis for induction of ocular dominance plasticity. J. Neurobiol. 41:(1):1999 (Oct.);83-91
3. Bruno V, Battaglia G, Copani A, D'Onofrio M, Di Iorio P, De Blasi A, Melchiorri D, Flor P.J, Nicoletti F. Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs. J. Cereb. Blood Flow Metab. 21:(9):2001 (Sep.);1013-1033
4. Casabona G, Genazzani A.A, Di Stefano M, Sortino M.A, Nicoletti F. Developmental changes in the modulation of cyclic AMP formation by the metabotropic glutamate receptor agonist 1S,3R-aminocyclopentane-1,3-dicarboxylic acid in brain slices. J. Neurochem. 59:(3):1992 (Sep.);1161-1163
5. Casabona G, Knöpfel T, Kuhn R, Gasparini F, Baumann P, Sortino M.A, Copani A, Nicoletti F. Expression and coupling to polyphosphoinositide hydrolysis of group-I metabotropic glutamate receptors in early postnatal and adult rat brain. Eur. J. Neurosci. 9:1997;12-17
6. Catania M.V, Landwehrmeyer G.B, Testa C.M, Standaert D.M, Penney H.B Jr., Young A.B. Metabotropic glutamate receptors are differentially regulated during development. Neuroscience. 61:1994;481-495
7. Catania M.V, Bellomo M, Di Giorgi-Gerevini V, Seminara G, Giuffrida R, Romeo R, De Blasi A, Nicoletti F. Endogenous activation of group-I metabotropic glutamate receptors is required for differentiation and survival of cerebellar Purkinje cells. J. Neurosci. 21:(19):2001 (Oct. 1);7664-7673
8. Ciccarelli R, Sureda F.X, Casabona G, Di Iorio P, Caruso A, Spinella F, Condorelli D.F, Nicoletti F, Caciagli F. Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture. Glia. 21:(4):1997 (Dec.);390-398
9. De Blasi A, Conn P.J, Pin J, Nicoletti F. Molecular determinants of metabotropic glutamate receptor signaling. Trends Pharmacol. Sci. 22:(3):2001 (Mar.);114-120
10. Defagot M.C, Villar M.J, Antonelli M.C. Differential localization of metabotropic glutamate receptors during postnatal development. Dev. Neurosci. 24:(4):2002;272-282
11. Dudek S.M, Bear M.F. A biochemical correlate of the critical period for synaptic modification in the visual cortex. Science. 246:(4930):1989 (Nov. 3);673-675
12. Frati C, Marchese C, Fisichella G, Copani A, Nasca M.R, Storto M, Nicoletti F. Expression of functional mGlu5 metabotropic glutamate receptors in human melanocytes. J. Cell. Physiol. 183:(3):2000 (Jun);364-372
13. Furuta A, Martin L.J. Laminar segregation of the cortical plate during corticogenesis is accompanied by changes in glutamate receptor expression. J. Neurobiol. 39:(1):1999 (Apr.);67-80
14. Goldowitz D, Hamre K. The cells and molecules that make a cerebellum. Trends Neurosci. 21:1998;375-382
15. Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K, Mishina M, Hashikawa T, Konnert A, Watanabe M, Kano M. Roles of glutamate receptor delta 2 subunit (GluRdelta2) and metanotropic glutamate receptor subtype 1 (mGluR1) in climbing fiber synapse elimination during postnatal cerebellar development. J. Neurosci. 21:(24):2001 (Dec. 15);9701-9712
16. Hashimoto K, Miyata M, Watanabe M, Kano M. Roles of phospholipase Cbeta4 in synapse elimination and plasticity in developing and mature cerebellum. Mol. Neurobiol. 23:(1):2001 (Feb.);69-82
17. Jokel E.S, Garduno E.R, Ariano M.A, Levine M.S. Metabotropic glutamate receptors mGluR1alpha and mGluR2/3 display dynamic expression patterns in developing rat striatum. Dev. Neurosci. 23:(1):2001;1-6
18. Kawabata S, Kohara A, Tsutsumi R, Itahana H, Hayashibe S, Yamaguchi T, Okada M. Diversity of calcium signaling by metabotropic glutamate receptors. J. Biol. Chem. 273:(28):1998 (Jul. 10);17381-17385
19. Konnerth A, Watanabe M, Kano M. Roles of glutamate receptor delta 2 subunit (GluR delta 2) and metabotropic glutamate receptor subtype 1 (mGluR1) in climbing fiber synapse elimination during postnatal cerebellar development. J. Neurosci. 21:(24):2001 (Dec. 15);9701-9712
20. Lopez-Bendito G, Shigemoto R, Lujan R, Juiz J.M. Developmental changes in the localisation of the mGluR1alpha subtype of metabotropic glutamate receptors in Purkinje cells. Neuroscience. 105:(2):2001;413-416
21. Lopez-Bendito G, Shigemoto R, Fairen A, Lujan R. Differential distribution of group I metabotropic glutamate receptors during rat cortical development. Cereb. Cortex. 12:(6):2002 (Jun);625-638
22. Lu Y.-M, Jia Z, Janus C, Henderson J.H, Gerali R, Wojtowicz J.M, Roder J.C. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J. Neurosci. 17:1997;5196-5205
23. Munoz A, Liu X.B, Jones E.G. Development of metabotropic glutamate receptors from trigeminal nuclei to barrel cortex in postnatal mouse. J. Comp. Neurol. 409:(4):1999 (Jul 12);549-566
24. Meguro R, Ohishi H, Hoshino K, Hicks T.P, Norita M. Metabotropic glutamate receptor 2/3 immunoreactivity in the developing rat cerebellar cortex. J. Comp. Neurol. 410:(2):1999 (Jul 26);243-255
25. Neugebauer V. Peripheral metabotropic glutamate receptors: fight the pain where it hurts. Trends Neurosci. 24:(10):2001 (Oct.);550-552
26. Nicoletti F, Wroblewski J.T, Novelli A, Alho H, Guidotti A, Costa E. The activation of inositol phospholipid hydrolysis as a signal transducing system for excitatory amino acids in primary cultures of cerebellar granule cells. J. Neurosci. 6:1986;1905-1911
27. O'Malley K.L, Jong Y.J, Gonchar Y, Burkhalter A, Romano C. Activation of metabotropic glutamate receptor mGlu5 on nuclear membranes mediates intranuclear Ca2+ changes in heterologous cell types and neurons. J. Biol. Chem. 278:(30):2003 (Jul 25);28210-28219
28. Palucha A, Branski P, Kroczka B, Wieronska J, Pilc A. Developmental changes in the modulation of cyclic AMP accumulation by activation of metabotropic glutamate receptors. Pol. J. Pharmacol. 53:(5):2001 (Sep-Oct.);481-486
29. Pin J.-P, Duvoisin R. The metabotropic glutamate receptors: structure and functions. Neuropharmacology. 34:1995;1-26
30. Prather R.S. Basic mechanisms of fertilization and parthenogenesis in pigs. Reprod. Suppl. 58:2001;105-112
31. Reynolds B.A, Weiss S. Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev. Biol. 175:1996;1-13
32. Romano C, Van den Pol A, O'Malley K.L. Enhanced early developmental expression of the metabotropic glutamate receptor mGluR5 in rat brain: protein, mRNA splice variants, and regional distribution. J. Comp. Neurol. 367:1996;403-412
33. Storto M, de Grazia U, Knopfel T, Canonico P.L, Copani A, Richelmi P, Nicoletti F, Vairetti M. Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage. Hepatology. 31:(3):2000 (Mar.);649-655
34. Valerio A, Rizzonelli P, Paterlini M, Moretto G, Knopfel T, Kuhn R, Memo M, Spano P. mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. Neurosci. Res. 28:(1):1997 (May);49-57
35. van den Pol A.N, Kogelman L, Ghosh P, Liljelund P, Blackstone C. Developmental regulation of the hypothalamic metabotropic glutamate receptor mGluR1. J. Neurosci. 14:(6):1994 (Jun);3816-3834
36. van den Pol A.N, Obrietan K, Cao V, Trombley P.Q. Embryonic hypothalamic expression of functional glutamate receptors. Neuroscience. 67:(2):1995 (Jul);419-439
37. Roelen B.A, Lin H.Y, Knezevic V, Freund E, Mummery C.L. Expression of TGF-beta s and their receptors during implantation and organogenesis of the mouse embryo. Dev. Biol. 166:1994;716-728
38. Poli A, Lucchi R, Storto M, De Paolis P, Notari S, Nicoletti F, Casabona G. Predominant expression of group-II metabotropic glutamate receptors in the goldfish brain. Brain Res. 10:1999;142-145