Antagonism of the mGlu5 agonist 2-chloro-5-hydroxyphenylglycine by the novel selective mGlu5 antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) in the thalamus

British Journal of Pharmacology

Volumn 127, Issue 5, 1999, Pages 1057-1059

  Salt, T E ^a   Binns, K E ^a   Turner, J P ^a   Gasparini, F ^b   Kuhn, R ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

(R,S) 2 Chloro 5 hydroxyphenylglycine; 6 methyl 2 (phenylethynyl) pyridine; CHPG; Iontophoresis; Metabotropic glutamate receptor; mGlu5; MPEP; Sensory system; Thalamus

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 4 CARBOXYPHENYLGLYCINE; 6 METHYL 2 (PHENYLETHYNYL) PYRIDINE; METABOTROPIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; NEUROPHARMACOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; THALAMUS;

ANIMALS; CYCLOLEUCINE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; PHENYLACETATES; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; THALAMUS;

EID: 0032787781     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702677     Document Type: Article

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