Superiority of a new gradient system utilizing a critical threshold for the adsorption capacity of polypeptides to column packing when compared with a standard gradient system for the simultaneous and quantitative analysis of polypeptides

Biomedical Chromatography

Volumn 22, Issue 8, 2008, Pages 857-866

  Goda, Ryoya ^a   Masumoto, Hiroshi ^a   Okazaki, Osamu ^a   Sudo, Kenichi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Loading volume; New gradient system; Precision; Reversed phase HPLC; Sensitivity; Simultaneous and quantitative analysis

Indexed keywords

ACETONITRILE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; POLYPEPTIDES;

ADSORPTION CAPACITIES; COLUMN PACKINGS; CRITICAL THRESHOLD; GRADIENT SYSTEMS; LOADING VOLUMES; NEW GRADIENT SYSTEM; PRECISION; REVERSED PHASE HPLC; SENSITIVITY; SIMULTANEOUS AND QUANTITATIVE ANALYSE;

ADSORPTION;

ACETONITRILE; AMYLOID BETA PROTEIN; BRADYKININ; CARRIER PROTEINS AND BINDING PROTEINS; CORTICOTROPIN; INSULIN; MIDKINE; NEUROMEDIN C; NUCLEAR FACTOR Y; OXYTOCIN; POLYPEPTIDE; PROTEIN BNP32; PROTEIN CNP53; PROTEIN GRF; UROCORTIN;

ADSORPTION KINETICS; ARTICLE; CONTROLLED STUDY; HUMAN; INTERMETHOD COMPARISON; NONHUMAN; PEPTIDE ANALYSIS; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS;

EID: 50049090104     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1003     Document Type: Article

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