Mitochondrial SNPs associated with Japanese centenarians, Alzheimer's patients, and Parkinson's patients

Computational Biology and Chemistry

Volumn 32, Issue 5, 2008, Pages 332-337

  Takasaki, Shigeru ^a  

^a RIKEN YOKOHAMA INSTITUTE   (Japan)

Author keywords

Alzheimer's disease; Association; Centenarian; Haplogroup; Mitochondrial SNP; Parkinson's disease; Radial basis function (RBF)

Indexed keywords

AMINES; AMINO ACIDS; DNA; FEEDFORWARD NEURAL NETWORKS; HEALTH; NUCLEIC ACIDS; NUCLEOTIDES; ORGANIC ACIDS;

ALZHEIMER; ALZHEIMER'S DISEASE; ASSOCIATION; CENTENARIAN; HAPLOGROUP; MITOCHONDRIAL DNA; MITOCHONDRIAL FUNCTIONS; MITOCHONDRIAL SNP; NONSYNONYMOUS NUCLEOTIDE SUBSTITUTIONS; PARKINSON; PARKINSON'S DISEASE; RADIAL BASIS FUNCTION (RBF); RADIAL-BASIS FUNCTION; SINGLE-NUCLEOTIDE POLYMORPHISM; SYNONYMOUS NUCLEOTIDE SUBSTITUTIONS;

RADIAL BASIS FUNCTION NETWORKS;

MITOCHONDRIAL DNA;

AGED; ALZHEIMER DISEASE; ARTICLE; ARTIFICIAL NEURAL NETWORK; ASIAN; ETHNOLOGY; FEMALE; GENE FREQUENCY; GENETICS; HAPLOTYPE; HUMAN; JAPAN; LONGEVITY; MALE; MITOCHONDRION; PARKINSON DISEASE; PHYSIOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL;

AGED, 80 AND OVER; ALZHEIMER DISEASE; ASIAN CONTINENTAL ANCESTRY GROUP; DNA, MITOCHONDRIAL; FEMALE; GENE FREQUENCY; HAPLOTYPES; HUMANS; JAPAN; LONGEVITY; MALE; MITOCHONDRIA; MODELS, STATISTICAL; NEURAL NETWORKS (COMPUTER); PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 49949097316     PISSN: 14769271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compbiolchem.2008.03.014     Document Type: Article

References (24)

1. Alexe G., Fuku N., Bilal E., et al. Enrichment of longevity phenotype in mtDNA haplogroups D4b2b, D4a, and D4 in the Japanese population. Hum. Genet. 121 (2007) 347-356
2. Chagnon P., Gee M., Filion M., et al. Phylogenetic analysis of the mitochondrial genome indicates significant differences between patients with Alzheimer disease and controls in aFrench-Canadian founder population. Am. J. Med. Genet. 85 (1999) 20-30
3. Dawson T.M., and Dawson V.L. Molecular pathway of neurodegeneration in Parkinson's disease. Science 302 (2003) 819-822
4. Herrnstad C., Elson J.L., Fahy E., et al. Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for major African, Asian and European haplogroups. Am. J. Hum. Genet. 70 (2002) 1152-1171
5. Ivanova R., Lepage V., Charron D., and Schachter F. Mitochondrial genotype associated with French Caucasian centenarians. Gerontology 44 (1998) 349
6. Kong Q.-P., Yao Y.-G., Sun C., Bandelt H.-J., Zhu C.-L., and Zhang Y.-P. Phylogeny of East Asian mitochondrial DNA lineages inferred from complete sequences. Am. J. Hum. Genet. 73 (2003) 671-676
7. Kosel S., Egensperger R., Mehraein P., and Graeber M.B. No association of mutations at nucleotide 5460 of mitochondrial NADH dehydrogenase with Alzheimer's disease. Biochem. Biophys. Res. Commun. 203 (1994) 745-749
8. Lin F., Lin R., Wisniewski H.M., Hwang Y., Grundke-Iqbal I., Healy-Louie G., and Iqbal K. Detection of point mutations in codon 331 of mitochondrial NADH dehydrogenase subunit 2 in Alzheimer's brains. Biochem. Biophys. Res. Commun. 182 (1992) 238-246
9. Lustbader J.W., Cirilli M., Lin C., Xu H.W., Takuma K., et al. ABAB directly links Aβ to mitochondrial toxicity in Alzheimer's disease. Science 16 (2004) 448-452
10. Mayr-Wohlfart U., Paulus C., and Rodel G. Mitochondrial DNA mutations in multiple sclerosis patients with severe optic involvement. Acta Neurol. Scand. 94 (1996) 167-171
11. Niemi A.K., Moilanen J.S., Tanaka M., Hervonen A., et al. A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects. Eur. J. Hum. Genet. 13 (2005) 166-170
12. Poggio T., and Girosi F. Networks for approximation and learning. Proc. IEEE 78 (1990) 1481-1497
13. Ross O.A., MaCormack R., Maxwell L.D., Duguid R.A., Quinn D.J., et al. mt4216C variant in linkage with the mtDNA TJ cluster may confer a susceptibility to mitochondrial dysfunction resulting in an increased risk of Parkinson's disease in Irish. Exp. Gerontol. 38 (2003) 397-405
14. Schnopp N.M., Kosel S., Egensperger R., and Graeber M.B. Regional heterogeneity of mtDNA hetroplasmy in parkinsonian brain. Clin. Neuropathol. 15 (1996) 348-352
15. Schoffner J.M., Brown M.D., Torroni A., et al. Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients. Genomics 17 (1993) 171-184
16. Simon D.K., Mayeux R., Marder K., Kowall N.W., Beal M.F., and Jons D.R. Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurogy 54 (2000) 703-709
17. Takasaki T., Kawamura Y., Konagaya A., 2006. Selecting effective siRNA sequences by using radial basis function network and decision tree learning, BMC Bioinformatics 7 s5-s22, doi:10.1186/147-2105-7-s5-s22.
18. Tanaka M., Gong J.S., Zhang J., Yoneda M., and Yagi K. Mitochondrial genotype associated with longevity. Lancet 351 (1998) 185-186
19. Tanaka M., Fuku N., Takeyasu T., Guo L., Hirose R., Kurata M., et al. Golden mean to longevity: rareness of mitochondrial cytochrome b varianats in centenarians but not in patients with Parkinson's disease. J. Neuro. Res. 70 (2002) 347-355
20. Tanaka M., Cabrera V.M., Gonzalez A.M., et al. Mitochondrial genome variation in Eastern Asia and the peopling of Japan. Genome Res. 14 (2004) 1832-1850
21. Taylor R.W., and Turnbull D.M. Mitochondrial DNA mutations in human disease. Nat. Rev. Genet. 6 (2005) 389-402
22. Vila M., and Przedborski S. Targeting programmed cell death neurodegenerative diseases. Nat. Rev. Neurol. 4 (2003) 1-11
23. Wallace D.C. Mitochondrial diseases in man and mouse. Science 283 (1999) 1482-1488
24. Wu C.H., and McLarty J.W. Neural Networks and Genome Informatics (2000), Elsevier Science Ltd.