Golden mean to longevity: Rareness of mitochondrial cytochrome b variants in centenarians but not in patients with Parkinson's disease

Journal of Neuroscience Research

Volumn 70, Issue 3, 2002, Pages 347-355

  Tanaka, Masashi ^a,b   Fuku, Noriyuki ^a,b,c,d   Takeyasu, Takeshi ^a,b,d   Guo, Li Jun ^a,b,d   Hirose, Raita ^a,b,c   Kurata, Miyuki ^a   Borgeld, Harm Jan W ^a,b,c   Yamada, Yoshiji ^a,b   Maruyama, Wakako ^e   Arai, Yasumichi ^f   Hirose, Nobuyoshi ^f   Oshida, Yoshiharu ^d   Sato, Yuzo ^d   Hattori, Nobutaka ^g   Mizuno, Yoshikuni ^g   Iwata, So ^h   Yagi, Kunio ^a,b  

^a GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY   (Japan)

^b Institute of Applied Biochemistry   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d NAGOYA UNIVERSITY   (Japan)

^e NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^f KEIO UNIVERSITY   (Japan)

^g JUNTENDO UNIVERSITY   (Japan)

^h UPPSALA UNIVERSITY   (Sweden)

Author keywords

Amino acid variation; Mitochondrial DNA; Single nucleotide polymorphism

Indexed keywords

CYTOCHROME B; ENZYME VARIANT; MITOCHONDRIAL DNA;

ADULT; AGED; AGING; AMINO ACID SUBSTITUTION; ARTICLE; CONSENSUS SEQUENCE; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; LONGEVITY; MAJOR CLINICAL STUDY; MITOCHONDRION; NORMAL HUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; BASE SEQUENCE; CYTOCHROME B GROUP; DIABETES MELLITUS; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; GENETIC SCREENING; HUMANS; LONGEVITY; MUTATION; OBESITY; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PARKINSON DISEASE; POINT MUTATION; POLYMORPHISM, GENETIC; PROTEIN STRUCTURE, TERTIARY; VARIATION (GENETICS);

EID: 0037010311     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10444     Document Type: Article

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