Serotonin 5-HT2B Receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice

Hypertension

Volumn 52, Issue 2, 2008, Pages 301-307

  Monassier, Laurent ^a   Laplante, Marc André ^b   Jaffré, Fabrice ^a   Bousquet, Pascal ^a   Maroteaux, Luc ^a   De Champlain, Jacques ^b  

^a INSERM   (France)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

5 HT2b; Adrenergic; Angiotensin; Cardiac; Hypertrophy; NAD(P)H oxidase; Superoxide anion

Indexed keywords

ANGIOTENSIN II; ISOPRENALINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SB 215505; SEROTONIN 2 ANTAGONIST; SEROTONIN 2B RECEPTOR; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; INDOLE DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; QUINOLINE DERIVATIVE; SEROTONIN ANTAGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; FIBROBLAST; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BLOCKING; TACHYCARDIA; ANIMAL; CARDIOMEGALY; COMPARATIVE STUDY; DISEASE MODEL; DOPPLER ECHOCARDIOGRAPHY; DRUG EFFECT; ECHOGRAPHY; METABOLISM; MOUSE STRAIN; PROBABILITY; RANDOMIZATION; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY;

ANGIOTENSIN II; ANIMALS; CARDIOMEGALY; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY, DOPPLER; INDOLES; ISOPROTERENOL; MICE; MICE, INBRED STRAINS; NADP; PROBABILITY; QUINOLINES; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; RECEPTOR, SEROTONIN, 5-HT2B; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SEROTONIN ANTAGONISTS; SUPEROXIDES;

EID: 49849101213     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.105551     Document Type: Article

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