Regulatory effects of antihistamines on the responses to staphylococcal enterotoxin B of human monocyte-derived dendritic cells and CD4+ T cells

Journal of Dermatological Science

Volumn 52, Issue 1, 2008, Pages 31-38

  Iida, Hideyuki ^a   Asada, Hideo ^a   Yokoi, Shoko ^a   Niizeki, Hironori ^a   Yasuda, Yasuki ^a   Miyagawa, Sachiko ^a   Kita, Eiji ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Antihistamine; CD54; Chemokine; Cytokine; Dendritic cell; ELISA; Epinastine; Flow cytometry; ICAM 1; IFN gamma; IL 4; IP 10; Ketotifen; Loratadine; MDC; Mig; Proliferation; SEB; Staphylococcal enterotoxin B; T cell; TARC; TNF alpha

Indexed keywords

ANTIHISTAMINIC AGENT; CD3 ANTIBODY; CHEMOKINE; CXCL9 CHEMOKINE; CYTOKINE; EPINASTINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 4; KETOTIFEN; LORATADINE; MACROPHAGE DERIVED CHEMOKINE; MONOCLONAL ANTIBODY CD28; STAPHYLOCOCCUS ENTEROTOXIN B; TACROLIMUS; THYMUS AND ACTIVATION REGULATED CHEMOKINE;

ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADAM PROTEINS; ADULT; ANTIBODIES, MONOCLONAL; ANTIGENS, CD28; ANTIGENS, CD3; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CHEMOKINE CCL17; CHEMOKINE CXCL10; CHEMOKINE CXCL9; COCULTURE TECHNIQUES; DENDRITIC CELLS; ENTEROTOXINS; HISTAMINE H1 ANTAGONISTS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; INTERLEUKIN-4; MIDDLE AGED; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS;

EID: 49849087158     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2008.04.004     Document Type: Article

References (39)

1. Tasaka K. Epinastine: an update of its pharmacology, metabolism, clinical efficacy and tolerability in the treatment of allergic diseases. Drugs Today 36 (2000) 735-757
2. Langeland T., Fagertun H.E., and Larsen S. Therapeutic effect of loratadine on pruritus in patients with atopic dermatitis. A multi-crossover-designed study. Allergy 49 (1994) 22-26
3. Grant S.M., Goa K.L., Fitton A., Sorkin E.M., and Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders. Drugs 40 (1990) 412-448
4. Massey W.A., and Lichtenstein L.M. The effects of antihistamines beyond H1 antagonism in allergic inflammation. J Allergy Clin Immunol 86 (1990) 1019-1024
5. Crampette L., Mainprice B., Bloom M., Bousquet J., and Campbell A.M. Inhibition of mediator and cytokine release from dispersed nasal polyp cells by terfenadine. Allergy 51 (1996) 346-349
6. Maeda A., Matsushita K., Yamazaki F., Kawada A., Tezuka T., and Aragane Y. Terfenadine antagonism against interleukin-4-modulated gene expression of T cell cytokines. J Invest Dermatol 121 (2003) 490-495
7. Nori M., Iwata S., Munakata Y., et al. Ebastine inhibits T cell migration, production of Th2-type cytokines and proinflammatory cytokines. Clin Exp Allergy 33 (2003) 1476-1478
8. Munakata Y., Umezawa Y., Iwata S., Dong R.P., Yoshida S., Ishii T., and Morimoto C. Specific inhibition of TH2-type cytokine production from human peripheral T cells by terfenadine in vitro. Clin Exp Allergy 29 (1999) 1281-1286
9. Kanai K., Asano K., Hisamitsu T., and Suzaki H. Suppressive activity of epinastine hydrochloride on TARC production from human peripheral blood CD4+ T cells in vitro. J Pharm Pharmacol 57 (2005) 1027-1036
10. Kanai K., Asano K., Watanabe S., Kyo Y., and Suzaki H. Epinastine hydrochloride antagonism against interleukin-4-mediated T cell cytokine imbalance in vitro. Int Arch Allergy Immunol 140 (2006) 43-52
11. Imai T., Nagira M., Takagi S., Kakizaki M., Nishimura M., Wang J., Gray P.W., Matsushima K., and Yoshie O. Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int Immunol 11 (1999) 81-88
12. Sauty A., Dziejman M., Taha R.A., Iarossi A.S., Neote K., Garcia-Zepeda E.A., Hamid Q., and Luster A.D. The T cell-specific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells. J Immunol 162 (1999) 3549-3558
13. Hashimoto S., Nakamura K., Oyama N., Kaneko F., Tsunemi Y., Saeki H., and Tamaki K. Macrophage-derived chemokine (MDC)/CCL22 produced by monocyte derived dendritic cells reflects the disease activity in patients with atopic dermatitis. J Dermatol Sci 44 (2006) 93-99
14. Shimada Y., Takehara K., Sato S., and Both Th2. Th1 chemokines (TARC/CCL17, MDC/CCL22, and Mig/CXCL9) are elevated in sera from patients with atopic dermatitis. J Dermatol Sci 34 (2004) 201-208
15. Villagomez M.T., Bae S.J., Ogawa I., Takenaka M., and Katayama I. Tumour necrosis factor-alpha but not interferon-gamma is the main inducer of inducible protein-10 in skin fibroblasts from patients with atopic dermatitis. Br J Dermatol 150 (2004) 910-916
16. Kapsenberg M.L. Dendritic-cell control of pathogen-driven T-cell polarization. Nat Rev Immunol 3 (2003) 984-993
17. Aiba S., Manome H., Yoshino Y., and Tagami H. Alteration in the production of IL-10 and IL-12 and aberrant expression of CD23, CD83 and CD86 by monocytes or monocyte-derived dendritic cells from atopic dermatitis patients. Exp Dermatol 12 (2003) 86-95
18. Gloor M., Peters G., and Stoika D. On the resident aerobic bacterial skin flora in unaffected skin of patients with atopic dermatitis and in healthy controls. Dermatologica 164 (1982) 258-265
19. Hoeger P.H., Lenz W., Boutonnier A., and Fournier J.M. Staphylococcal skin colonization in children with atopic dermatitis: prevalence, persistence, and transmission of toxigenic and nontoxigenic strains. J Infect Dis 165 (1992) 1064-1068
20. Leung D.Y., Harbeck R., Bina P., Reiser R.F., Yang E., Norris D.A., Hanifin J.M., and Sampson H.A. Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J Clin Invest 92 (1993) 1374-1380
21. Strange P., Skov L., Lisby S., Nielsen P.L., and Baadsgaard O. Staphylococcal enterotoxin B applied on intact normal and intact atopic skin induces dermatitis. Arch Dermatol 132 (1996) 27-33
22. Li L., Crowley M., Nguyen A., and Lo D. Ability of a nondepleting anti-CD4 antibody to inhibit Th2 responses and allergic lung inflammation is independent of coreceptor function. J Immunol 163 (1999) 6557-6566
23. Amon U., Gibbs B.F., Buss G., and Nitschke M. In vitro investigations with the histamine H1 receptor antagonist, epinastine (WAL 801 CL), on isolated human allergic effector cells. Inflamm Res 49 (2000) 112-116
24. Kaminuma O., Ogawa K., Kikkawa H., Kikuchi M., Naito K., and Ikezawa K. A novel anti-allergic drug, betotastine besilate, suppresses interleukin-5 production by human peripheral blood mononuclear cells. Biol Pharm Bull 21 (1998) 411-413
25. Mullol J., Roca-Ferrer J., Alobid I., Pujols L., Valero A., Xaubet A., Bernal-Sprekelsen M., and Picado C. Effect of desloratadine on epithelial cell granulocyte-macrophage colony-stimulating factor secretion and eosinophil survival. Clin Exp Allergy 36 (2006) 52-58
26. Saeki S., Matsuse H., Kondo Y., Machida I., Kawano T., Tomari S., Obase Y., Fukushima C., and Kohno S. Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients. J Allergy Clin Immunol 114 (2004) 538-544
27. 2 up-regulate the production of Th2-attracting chemokines (CCL17 and CCL22) and down-regulate IFN-gamma-induced CXCL10 production by immature human dendritic cells. Immunology 117 (2006) 507-516
28. Vulcano M., Albanesi C., Stoppacciaro A., et al. Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo. Eur J Immunol 31 (2001) 812-822
29. Penna G., Vulcano M., Roncari A., Facchetti F., Sozzani S., and Adorini L. Cutting edge: differential chemokine production by myeloid and plasmacytoid dendritic cells. J Immunol 169 (2002) 6673-6676
30. Fujita H., Asahina A., Sugaya M., Nakamura K., Gao P., Fujiwara H., and Tamaki K. Differential production of Th1- and Th2-type chemokines by mouse Langerhans cells and splenic dendritic cells. J Invest Dermatol 124 (2005) 343-350
31. Lebre M.C., Burwell T., Vieira P.L., Lora J., Coyle A.J., Kapsenberg M.L., Clausen B.E., and De Jong E.C. Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation. Immunol Cell Biol 83 (2005) 525-535
32. Smits H.H., de Jong E.C., Schuitemaker J.H., Geijtenbeek T.B., van Kooyk Y., Kapsenberg M.L., and Wierenga E.A. Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development. J Immunol 168 (2002) 1710-1716
33. Lin Y.T., Wang C.T., Hsu C.T., Wang L.F., Shau W.Y., Yang Y.H., and Chiang B.L. Differential susceptibility to staphylococcal superantigen (SsAg)-induced apoptosis of CD4+ T cells from atopic dermatitis patients and healthy subjects: the inhibitory effect of IL-4 on SsAg-induced apoptosis. J Immunol 171 (2003) 1102-1108
34. Van Seventer G.A., Shimizu Y., Horgan K.J., and Shaw S. The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells. J Immunol 144 (1990) 4579-4586
35. Grewe M., Gyufko K., Schopf E., and Krutmann J. Lesional expression of interferon-gamma in atopic eczema. Lancet 343 (1994) 25-26
36. Werfel T., Morita A., Grewe M., Renz H., Wahn U., Krutmann J., and Kapp A. Allergen specificity of skin-infiltrating T cells is not restricted to a type-2 cytokine pattern in chronic skin lesions of atopic dermatitis. J Invest Dermatol 107 (1996) 871-876
37. Hamid Q., Boguniewicz M., and Leung D.Y. Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis. J Clin Invest 94 (1994) 870-876
38. Leung D.Y. Pathogenesis of atopic dermatitis. J Allergy Clin Immunol 104 (1999) S99-108
39. Takahashi T., Sasaki Y., Hama K., Furue M., and Ishibashi Y. Production of IL-4, IL-2, IFN-gamma, and TNF-alpha by peripheral blood mononuclear cells of patients with atopic dermatitis. J Dermatol Sci 3 (1992) 172-180