Identification of peptides that inhibit regulator of G protein signaling 4 function

Pharmacology

Volumn 82, Issue 2, 2008, Pages 97-104

  Wang, Yuren ^a   Lee, Yan ^a   Zhang, Jie ^a   Young, Kathleen H ^a  

^a PFIZER INC   (United States)

Author keywords

G proteins; GTPase activating protein; Regulator of G protein signaling 4; Yeast two hybrid system

Indexed keywords

ARGININE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MUSCARINIC M2 RECEPTOR; PEPTIDE; PEPTIDE LIBRARY; RGS4 PROTEIN; UNCLASSIFIED DRUG; VALYLARGINYLHISTIDYLVALYLALANYLVALYLGLUTAMYLVALYLGLYCYLGLYCYLVALYLVALYLVALYLVALY LVALYLGLYCINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ELECTROPHYSIOLOGY; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TWO HYBRID SYSTEM; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ELECTROPHYSIOLOGY; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; OOCYTES; PEPTIDE LIBRARY; PEPTIDES; RECEPTOR, MUSCARINIC M2; RGS PROTEINS; SIGNAL TRANSDUCTION; TWO-HYBRID SYSTEM TECHNIQUES; XENOPUS LAEVIS;

EID: 49749136529     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000138387     Document Type: Article

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