BAFF is elevated in serum of patients with psoriasis: Association with disease activity

British Journal of Dermatology

Volumn 159, Issue 3, 2008, Pages 765-768

  Samoud El Kissi, S ^a,b   Galai, Y ^a   Sghiri, R ^b   Kenani, N ^b   Ben Alaya Bouafif, N ^a   Boukadida, J ^b   Denguezli, M ^b   Nouira, R ^b   Louzir, H ^a  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b FARHAT HACHED HOSPITAL   (Tunisia)

Author keywords

Autoantibodies; B cell activating factor; Psoriasis; Psoriatic arthropathy

Indexed keywords

B CELL ACTIVATING FACTOR; CENTROMERE ANTIBODY; DOUBLE STRANDED DNA ANTIBODY; NUCLEOSOME ANTIBODY; RO ANTIBODY; SCL 70 ANTIBODY;

ADOLESCENT; ADULT; AGED; ANTIBODY SPECIFICITY; ANTIBODY TITER; BLOOD SAMPLING; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; LETTER; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PSORIASIS; SCHOOL CHILD; SCORING SYSTEM;

ADOLESCENT; ADULT; AGED; ANTIBODIES, ANTINUCLEAR; B-CELL ACTIVATING FACTOR; CASE-CONTROL STUDIES; CHILD; FEMALE; HUMANS; MALE; MIDDLE AGED; PSORIASIS;

EID: 49749134765     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2008.08737.x     Document Type: Letter

References (10)

1. Kalled SL. Impact of the BAFF/BR3 axis on B cell survival, germinal centre maintenance and antibody production. Semin Immunol 2006 18 : 290 6.
2. Becker-Merok A, Nikolaisen C, Nossent HC. B-lymphocyte activating factor in systemic lupus erythematosus and rheumatoid arthritis in relation to autoantibody levels, disease measures and time. Lupus 2006 15 : 570 6.
3. Matsushita T, Hasegawa M, Matsushita Y et al. Elevated serum BAFF levels in patients with localized scleroderma in contrast to other organ-specific autoimmune diseases. Exp Dermatol 2007 16 : 87 93.
4. Asashima N, Fujimoto M, Watanabe R et al. Serum levels of BAFF are increased in bullous pemphigoid but not in pemphigus vulgaris. Br J Dermatol 2006 155 : 330 6.
5. Jullien D. Psoriasis physiopathology. J Eur Acad Dermatol Venereol 2006 20 (Suppl. 2 10 23.
6. Johnson SR, Schentag CT, Gladman DD. Autoantibodies in biological agent naive patients with psoriatic arthritis. Ann Rheum Dis 2005 64 : 770 2.
7. Nardelli B, Belvedere O, Roschke V et al. Synthesis and release of B lymphocyte stimulator from myeloid cells. Blood 2001 97 : 198 204.
8. Groom J, Kalled SL, Cutler AH et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. J Clin Invest 2002 109 : 59 68.
9. Ng LG, Sutherland AP, Newton R et al. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol 2004 173 : 807 17.
10. Sutherland AP, Ng LG, Fletcher CA et al. BAFF augments certain Th1-associated inflammatory responses. J Immunol 2005 174 : 5537 44.