Risk factors for the development of early-onset delirium and the subsequent clinical outcome in mechanically ventilated patients

Journal of Critical Care

Volumn 23, Issue 3, 2008, Pages 372-379

  Lin, Shu Min ^a   Huang, Chien Da ^a   Liu, Chien Ying ^a   Lin, Horng Chyuan ^a   Wang, Chun Hua ^a   Huang, Pei Yao ^a   Fang, Yueh Fu ^a   Shieh, Meng Heng ^a   Kuo, Han Pin ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Albumin; Delirium; Mortality; Risk factors; Sepsis; Ventilator

Indexed keywords

ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; CONFIDENCE INTERVAL; CONTROLLED STUDY; DELIRIUM; DISEASE COURSE; FEMALE; HOSPITAL INFECTION; HOSPITALIZATION; HUMAN; HYPOALBUMINEMIA; INCIDENCE; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE ANALYSIS; OUTCOME ASSESSMENT; PNEUMONIA; RISK FACTOR; SEPSIS; STATISTICAL SIGNIFICANCE; VENTILATED PATIENT;

AGED; AGED, 80 AND OVER; APACHE; COMORBIDITY; DELIRIUM; FEMALE; HOSPITAL COSTS; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; LENGTH OF STAY; MALE; MIDDLE AGED; RESPIRATION, ARTIFICIAL; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME;

EID: 49749093059     PISSN: 08839441     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcrc.2006.09.001     Document Type: Article

References (27)

1. Inouye S.K., Bogardus Jr. S.T., Charpentier P.A., et al. A multicomponent intervention to prevent delirium in hospitalized older patients. N Engl J Med 340 (1999) 669-676
2. Dubois M.J., Bergeron N., Dumont M., et al. Delirium in an intensive care unit: a study of risk factors. Intensive Care Med 27 (2001) 1297-1304
3. Ely E.W., Gautam S., Margolin R., et al. The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med 27 (2001) 1892-1900
4. Practice guideline for the treatment of patients with delirium. American Psychiatric Association. Am J Psychiatry 156 (1999) 1-20
5. Lukan J.K., Reed Jr. D.N., Looney S.W., et al. Risk factors for delirium tremens in trauma patients. J Trauma 53 (2002) 901-906
6. Milbrandt E.B., Deppen S., Harrison P.L., et al. Costs associated with delirium in mechanically ventilated patients. Crit Care Med 32 (2004) 955-962
7. Kakuma R., du Fort G.G., Arsenault L., et al. Delirium in older emergency department patients discharged home: effect on survival. J Am Geriatr Soc 51 (2003) 443-450
8. Lawlor P.G., Gagnon B., Mancini I.L., et al. Delirium as a predictor of survival in older patients with advanced cancer. Arch Intern Med 160 (2000) 2866-2868
9. Ely E.W., Shintani A., Truman B., et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 291 (2004) 1753-1762
10. Ely E.W., Inouye S.K., Bernard G.R., et al. Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). Jama 286 (2001) 2703-2710
11. Lin S.M., Liu C.Y., C.H. W., et al. The impact of delirium on the survival of mechanically ventilated patients. Crit Care Med 32 (2004) 2254-2259
12. Blessed G., Tomlinson B.E., and Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 114 (1968) 797-811
13. Ely E.W., Truman B., Shintani A., et al. Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS). JAMA 289 (2003) 2983-2991
14. O'Connor P.G., and Schottenfeld R.S. Patients with alcohol problems. N Engl J Med 338 (1998) 592-602
15. Bone R.C., Sibbald W.J., and Sprung C.L. The ACCP-SCCM consensus conference on sepsis and organ failure. Chest 101 (1992) 1481-1483
16. Teasdale G., and Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet 2 (1974) 81-84
17. Aldemir M., Ozen S., Kara I.H., et al. Predisposing factors for delirium in the surgical intensive care unit. Crit Care 5 (2001) 265-270
18. Eidelman L.A., Putterman D., Putterman C., et al. The spectrum of septic encephalopathy. Definitions, etiologies, and mortalities. JAMA 275 (1996) 470-473
19. Wyler F., Rutishauser M., and Weisser K. Endotoxin induced regional circulatory reactions in the rabbit with and without halothane anesthesia. J Surg Res 13 (1972) 13-19
20. Coelho A., Fioramonti J., and Bueno L. Brain interleukin-1beta and tumor necrosis factor-alpha are involved in lipopolysaccharide-induced delayed rectal allodynia in awake rats. Brain Res Bull 52 (2000) 223-228
21. Wong M.L., Bongiorno P.B., Rettori V., et al. Interleukin (IL) 1beta, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: pathophysiological implications. Proc Natl Acad Sci U S A 94 (1997) 227-232
22. Yokota H., Ogawa S., Kurokawa A., et al. Regional cerebral blood flow in delirium patients. Psychiatry Clin Neurosci 57 (2003) 337-339
23. Trzepacz P.T., and Francis J. Low serum albumin levels and risk of delirium. Am J Psychiatry 147 (1990) 675
24. Ljubisavljevic V., and Kelly B. Risk factors for development of delirium among oncology patients. Gen Hosp Psychiatry 25 (2003) 345-352
25. McNicoll L., Pisani M.A., Zhang Y., et al. Delirium in the intensive care unit: occurrence and clinical course in older patients. J Am Geriatr Soc 51 (2003) 591-598
26. O'Keeffe S., and Lavan J. The prognostic significance of delirium in older hospital patients. J Am Geriatr Soc 45 (1997) 174-178
27. Hoffken G., and Niederman M.S. Nosocomial pneumonia: the importance of a de-escalating strategy for antibiotic treatment of pneumonia in the ICU. Chest 122 (2002) 2183-2196