Quantitative structure carcinogenicity relationship for detecting structural alerts in nitroso-compounds. Species: Rat; Sex: Male; Route of administration: Water

Toxicology and Applied Pharmacology

Volumn 231, Issue 2, 2008, Pages 197-207

  Helguera, Aliuska Morales ^a,b   Cordeiro, M Natália D S ^a   Pérez, Miguel Ángel Cabrera ^b   Combes, Robert D ^c   González, Maykel Pérez ^b,d  

^a UNIVERSITY OF PORTO   (Portugal)

^b CENTRAL UNIVERSITY OF LAS VILLAS   (Cuba)

^c RUSSELL AND BURCH HOUSE   (United Kingdom)

^d UNIVERSITY OF VIGO   (Spain)

Author keywords

Carcinogenicity; Nitroso compounds; Structural alerts; TOPS MODE

Indexed keywords

ALKYL GROUP; HYDROXYL GROUP; NITROSAMINE; NITROSO DERIVATIVE; NITROSOUREA;

ARTICLE; BIOASSAY; BIOTRANSFORMATION; CARCINOGENICITY; CHEMICAL STRUCTURE; CHEMOMETRICS; HYDROGEN BOND; QUANTITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; DATABASES, FACTUAL; DRUG ADMINISTRATION ROUTES; HYDROPHOBICITY; MALE; MODELS, MOLECULAR; NITROSO COMPOUNDS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; WATER;

RATTUS;

EID: 49749085528     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.04.008     Document Type: Article

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