Calorie restriction minimizes activation of insulin signaling in response to glucose: Potential involvement of the growth hormone-insulin-like growth factor 1 axis

Experimental Gerontology

Volumn 43, Issue 9, 2008, Pages 827-832

  Hayashi, Hiroko ^a   Yamaza, Haruyoshi ^a   Komatsu, Toshimitsu ^a   Park, Seongjoon ^a   Chiba, Takuya ^a   Higami, Yoshikazu ^b   Nagayasu, Takeshi ^a   Shimokawa, Isao ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Akt; Calorie restriction; FoxO1; Glucose metabolism; Growth hormone insulin like growth factor 1 axis; Insulin signaling

Indexed keywords

GLUCOSE; GROWTH HORMONE; INSULIN; INSULIN RECEPTOR; PROTEIN KINASE B; SODIUM CHLORIDE; SOMATOMEDIN C; TRANSCRIPTION FACTOR FKHR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CALORIC RESTRICTION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; INSULIN BLOOD LEVEL; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; RAT; TRANSGENIC RAT; WILD TYPE;

ANIMALS; BLOOD GLUCOSE; CALORIC RESTRICTION; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE; GROWTH HORMONE; INSULIN; INSULIN-LIKE GROWTH FACTOR I; LIVER; MALE; MUSCLE, SKELETAL; NERVE TISSUE PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, TRANSGENIC; RATS, WISTAR; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

RATTUS; RATTUS NORVEGICUS;

EID: 49649116327     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2008.05.011     Document Type: Article

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