Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 32, 2008, Pages 11128-11133

  Freeman, Michael F ^a   Moshos, Kristos A ^a   Bodner, Micah J ^a   Li, Rongfeng ^a   Townsend, Craig A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

lactam antibiotics; Acylase; Carbapenem; Phosphatase; Pyrophosphatase

Indexed keywords

ACETYL COENZYME A; CARBAPENEM DERIVATIVE; COENZYME A; CYSTEINE; ENZYME; MERCAPTAMINE; PANTETHEINE PHOSPHATE; THIENAMYCIN; THNF ENZYME; THNH ENZYME; THNR ENZYME; THNT ENZYME;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; ENZYME ACTIVITY; GENE CLUSTER; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STREPTOMYCES;

BACTERIAL PROTEINS; COENZYME A; CYSTEAMINE; CYSTEINE; GENES, BACTERIAL; MULTIGENE FAMILY; PANTETHEINE; STREPTOMYCES; THIENAMYCINS;

STREPTOMYCES CATTLEYA;

EID: 49649113455     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804500105     Document Type: Article

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