Acute otitis media in children with tympanostomy tubes

Canadian Family Physician

Volumn 54, Issue 8, 2008, Pages 1123-1127

  Schmelzle, Jason ^a   Birtwhistle, Richard V ^a,b   Tan, Andre K W ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b Centre for Studies in Primary Care

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; CIPROFLOXACIN; CLAVULANIC ACID; CORTICOSTEROID; DEXAMETHASONE; OFLOXACIN; PLACEBO; PREDNISOLONE; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ACUTE OTITIS MEDIA; ANTIBIOTIC RESISTANCE; BACTERIAL GROWTH; COMMUNITY ACQUIRED INFECTION; COUGHING; DIARRHEA; EAR CLEANING; FEVER; HUMAN; HYGIENE; INFECTION; OTORRHEA; OTOTOXICITY; OUTCOME ASSESSMENT; PSEUDOMONAS; REVIEW; RHINITIS; SUCTION; SYSTEMIC THERAPY; TYMPANOSTOMY TUBE; UPPER RESPIRATORY TRACT INFECTION;

ACUTE DISEASE; ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ANTI-BACTERIAL AGENTS; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE, BACTERIAL; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; MALE; MIDDLE EAR VENTILATION; OTITIS MEDIA; OTITIS MEDIA, SUPPURATIVE; PREDNISOLONE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 49649109361     PISSN: 0008350X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (36)

1. McIsaac WJ, Coyte PC, Croxford R, Asche CV, Friedberg J, Feldman W. Otolaryngologists' perceptions of the indications for tympanostomy tube insertion in children. CMAJ 2000;162(9):1285-8.
2. Dohar J. Microbiology of otorrhea in children with tympanostomy tubes: implications for therapy. Int J Pediatr Otorhinolaryngol 2003;67(12):1317-23.
3. Siddiq MA, Narula AA. Persistent otorrhoea after ventilation tube insertion: a treatment protocol. Int J Clin Pract 2003;57(9):775-7.
4. Kay DJ, Nelson M, Rosenfeld RM. Meta-analysis of tympanostomy tube sequelae. Otolaryngol Head Neck Surg 2001;124(4):374-80.
5. Myer CM 3rd. Post-tympanostomy tube otorrhea. Ear Nose Throat J 2001;80(Suppl 6):4-7.
6. Daniel SJ, Kozak FK, Fabian MC, Hekkenberg R, Hruby LE, Harjee KS, et al. Guidelines for the treatment of tympanostomy tube otorrhea. J Otolaryngol 2005;34(Suppl 2):S60-3.
7. Manolidis S, Friedman R, Hannley M, Roland PS, Matz G, Rybak L, et al. Comparative efficacy of aminoglycoside versus fluoroquinolone topical antibiotic drops. Otolaryngol Head Neck Surg 2004;130(Suppl 3):S83-8.
8. Roland PS, Anon JB, Moe RD, Conroy PJ, Wall GM, Dupre SJ, et al. Topical ciprofloxacin/dexamethasone is superior to ciprofloxacin alone in pediatric patients with acute otitis media and otorrhea through tympanostomy tubes. Laryngoscope 2003;113(12):2116-22.
9. Ehmer DR, Roland PS. Management of the draining tympanostomy tube. Otorinolaringologia 2005;55(1):35-42.
10. Schroeder A, Darrow DH. Management of the draining ear in children. Pediatr Ann 2004;33(12):843-53.
11. Rosenfeld RM. Antibiotic use for otitis media: oral, topical or none? Pediatr Ann 2004;33(12):833-42.
12. Ruohola A, Heikkinen T, Meurman O, Puhakka T, Lindblad N, Ruuskanen O. Antibiotic treatment of acute otorrhea through tympanostomy tube: randomized double-blind placebo-controlled study with daily follow-up. Pediatrics 2003;111(5 Pt 1):1061-7.
13. Ruohola A, Heikkinen T, Jero J, Puhakka T, Juvén T, Närkiö-Mäkelä M, et al. Oral prednisolone is an effective adjuvant therapy for acute otitis media with discharge through tympanostomy tubes. J Pediatr 1999;134(4):459-63.
14. Goldblatt EL, Dohar J, Nozza RJ, Nielsen RW, Goldberg T, Sidman JD, et al. Topical ofloxacin versus systemic amoxicillin/clavulanate in purulent otorrhea in children with tympanostomy tubes. Int J Pediatr Otorhinolaryngol 1998;46(1-2):91-101.
15. Vaile L, Williamson T, Waddell A, Taylor G. Interventions for ear discharge associated with grommets (ventilation tubes). Cochrane Database Syst Rev 2006;(2):CD001933.
16. Dohar J, Giles W, Roland P, Bikhazi N, Carroll S, Moe R, et al. Topical ciprofloxacin/dexamethasone superior to oral amoxicillin/clavulanic acid in otitis media with otorrhea through tympanostomy tubes. Pediatrics 2006;118(3):e561-9. Epub 2006 Jul 31.
17. Roland PS, Kreisler LS, Reese B, Anon JB, Lanier B, Conroy PJ, et al. Topical ciprofloxacin/dexamethasone otic suspension is superior to ofloxacin otic solution in the treatment of children with acute otitis media with otorrhea through tympanostomy tubes. Pediatrics 2004;113(1 Pt 1):e40-6.
18. Dagan R, Leibovitz E, Cheletz G, Leiberman A, Porat N. Antibiotic treatment in acute otitis media promotes superinfection with resistant Streptococcus pneumoniae carried before initiation of treatment. J Infect Dis 2001;183(6):880-6. Epub 2001 Feb 9.
19. Weber PC, Roland PS, Hannley M, Friedman R, Manolidis S, Matz G, et al. The development of antibiotic resistant organisms with the use of ototopical medications. Otolaryngol Head Neck Surg 2004;130(Suppl 3):S89-94.
20. Klein JO. Strategies for decreasing multidrug antibiotic resistance: role of ototopical agents for treatment of middle ear infections. Am J Manag Care 2002;8(Suppl 14):S345-52.
21. Gates GA. Safety of ofloxacin otic and other ototopical treatments in animal models and in humans. Pediatr Infect Dis J 2001;20(1):104-7.
22. Denneny JC 3rd. Ototopical agents in the treatment of the draining ear. Am J Manag Care 2002;8(Suppl 14):S353-60.
23. Matz G, Rybak L, Roland PS, Hannley M, Friedman R, Manolidis S, et al. Ototoxicity of ototopical antibiotic drops in humans. Otolaryngol Head Neck Surg 2004;130(Suppl 3):S79-82.
24. Rotstein C, Mandell L. Clinical aminoglycoside ototoxicity. In: Roland PS, Rutka JA, editors. Ototoxicity. Hamilton, ON: BC Decker Inc; 2004. p. 82-92.
25. Wright CG, Roland PS. Middle ear effects of ototopical agents. In: Roland PS, Rutka JA, editors. Ototoxicity. Hamilton, ON: BC Decker Inc; 2004. p. 107-13.
26. Bance M, Rutka JA. Topical treatment for otorrhea: issues and controversies. J Otolaryngol 2005;34(Suppl 2):S52-5.
27. Rosser WW, Pennie RA, Pilla NJ; The Anti-infective Review Panel. Anti-infective guidelines for community-acquired infections. Toronto, ON: MUMS Guideline Clearinghouse; 2005.
28. Health Canada. Important safety reminder for patients using gentamicin sulfate-containing ear drops. Ottawa, ON: Health Canada; 2002. Available from: www.hc-sc.gc.ca/ahc-asc/media/advisories-avis/_2002/2002_43_e.html. Accessed 2008 May 27.
29. Ontario Medical Association, Section of Otolaryngology. Ototoxicity alert. Toronto, ON: Ontario Medical Association; 2004.
30. Gerber ME. The evolving role of ototopical therapy. Curr Opin Otolaryngol Head Neck Surg 2000;8(6):454-7.
31. Ramsey AM. Diagnosis and treatment of the child with a draining ear. J Pediatr Health Care 2002;16(4):161-9.
32. Haynes DS. Topical antibiotics: strategies for avoiding ototoxicity. Ear Nose Throat J 2004;83(Suppl 1):12-4.
33. Dohar JE, Kenna MA, Wadowsky RM. In vitro susceptibility of aural isolates of Pseudomonas aeruginosa to commonly used ototopical antibiotics. Am J Otol 1996;17(2):207-9.
34. Wai TK, Tong MC. A benefit-risk assessment of ofloxacin otic solution in ear infection. Drug Saf 2003;26(6):405-20.
35. Lexchin J, Bero LA, Djulbegovic B, Clark O. Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ 2003;326(7400):1167-70.
36. Easterbrook PJ, Berlin JA, Gopalan R, Matthews DR. Publication bias in clinical research. Lancet 1991;337(8746):867-72.