Newly weaned nonobese diabetic mice show heightened early diabetes sensitivity to multiple low doses of streptozotocin than nondiabetes-prone CD-1 mice: Initial beta-cell damage a key trigger for type 1 diabetes?

Pancreas

Volumn 37, Issue 1, 2008, Pages

  Reddy, Shiva ^a   Elliott, Robert B ^b   Chang, Mike ^a   Hsu, Tim ^a   Rodrigues, Jessica A ^a   Qiao, Linzi ^a   Robinson, Elizabeth ^c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c THE UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Early beta cell sensitivity; NOD mice; Streptozotocin; Type 1 diabetes

Indexed keywords

GLUCAGON; GLUCOSE TRANSPORTER 2; INSULIN; STREPTOZOCIN; SLC2A2 PROTEIN, MOUSE; SOMATOSTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD 1 MOUSE; CELL DAMAGE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; DOSE RESPONSE; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; MOUSE; MOUSE STRAIN; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATOSTATIN CELL; WEANING; AGE; ANIMAL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; EXPERIMENTAL DIABETES MELLITUS; HOSPITALIZATION; IMMUNOLOGY; MACROPHAGE; METABOLISM; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PATHOLOGY; SPECIES DIFFERENCE;

AGE FACTORS; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCOSE TRANSPORTER TYPE 2; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MACROPHAGES; MICE; MICE, INBRED NOD; SEVERITY OF ILLNESS INDEX; SOMATOSTATIN; SOMATOSTATIN-SECRETING CELLS; SPECIES SPECIFICITY; STREPTOZOCIN; WEANING;

EID: 49649093342     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3181661b1b     Document Type: Article

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