메뉴 건너뛰기




Volumn 111, Issue 1, 1998, Pages 9-19

Loss of glucose transporter-2 precedes insulin loss in the nonobese diabetic and the low-dose streptozotocin mouse models: A comparative immunohistochemical study by light and confocal microscopy

Author keywords

Cytotoxicity; Diabetes; Glucose transporter; Insulin; cell

Indexed keywords

GLUCOSE TRANSPORTER; INSULIN; STREPTOZOCIN;

EID: 0032127578     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1006/gcen.1998.7079     Document Type: Article
Times cited : (10)

References (37)
  • 1
    • 0025169983 scopus 로고
    • An overview on possible mechanisms of destruction of the insulin-producing beta cell
    • Cooke A. An overview on possible mechanisms of destruction of the insulin-producing beta cell. Curr. Top. Microbiol. 164:1990;125-142.
    • (1990) Curr. Top. Microbiol. , vol.164 , pp. 125-142
    • Cooke, A.1
  • 2
    • 0022617990 scopus 로고
    • Type 1 diabetes mellitus: A chronic autoimmune disease
    • Eisenbarth G. S. Type 1 diabetes mellitus: A chronic autoimmune disease. N. Engl. J. Med. 314:1986;1360-1368.
    • (1986) N. Engl. J. Med. , vol.314 , pp. 1360-1368
    • Eisenbarth, G.S.1
  • 4
    • 0027953701 scopus 로고
    • Autoimmune diabetes induced by the β-cell toxin STZ: Immunity to the 60-kDa heat shock protein and to insulin
    • Elias D., Prigozin H., Polak N., Rapoport M., Lohse A. W., Cohen I. R. Autoimmune diabetes induced by the β-cell toxin STZ: Immunity to the 60-kDa heat shock protein and to insulin. Diabetes. 43:1994;992-998.
    • (1994) Diabetes , vol.43 , pp. 992-998
    • Elias, D.1    Prigozin, H.2    Polak, N.3    Rapoport, M.4    Lohse, A.W.5    Cohen, I.R.6
  • 5
    • 0028784467 scopus 로고
    • Pancreatic islet glutz glucose transporter mRNA and protein expression in humans with and without NIDDM
    • Ferrer J., Gomis R., Alvarez J. F., Casamitjana R., Vilardell E. Pancreatic islet glutz glucose transporter mRNA and protein expression in humans with and without NIDDM. Diabetes. 44:1995;1369-1374.
    • (1995) Diabetes , vol.44 , pp. 1369-1374
    • Ferrer, J.1    Gomis, R.2    Alvarez, J.F.3    Casamitjana, R.4    Vilardell, E.5
  • 7
    • 0028055003 scopus 로고
    • Multiple low-dose streptozotocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes
    • Gerling I. C., Friedman H., Greiner D. L., Shultz L. D., Leiter E. H. Multiple low-dose streptozotocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes. Diabetes. 43:1994;433-440.
    • (1994) Diabetes , vol.43 , pp. 433-440
    • Gerling, I.C.1    Friedman, H.2    Greiner, D.L.3    Shultz, L.D.4    Leiter, E.H.5
  • 9
    • 0025242034 scopus 로고
    • Underexpression of β-cell high Km glucose transporters in non-insulin-dependent diabetes
    • Johnson J. H., Ogawa A., Chen L., Orci L., Newgard C. B., Alam T., Unger R. H. Underexpression of β-cell high Km glucose transporters in non-insulin-dependent diabetes. Science. 250:1990;546-549.
    • (1990) Science , vol.250 , pp. 546-549
    • Johnson, J.H.1    Ogawa, A.2    Chen, L.3    Orci, L.4    Newgard, C.B.5    Alam, T.6    Unger, R.H.7
  • 10
    • 0029934367 scopus 로고    scopus 로고
    • Loss of GLUT2 glucose transporter expression in pancreatic beta cells from diabetic Chinese hamsters
    • Jorns A., Teidge M., Sickel E., Lenzen S. Loss of GLUT2 glucose transporter expression in pancreatic beta cells from diabetic Chinese hamsters. Virchows Arch. 428:1996;177-185.
    • (1996) Virchows Arch. , vol.428 , pp. 177-185
    • Jorns, A.1    Teidge, M.2    Sickel, E.3    Lenzen, S.4
  • 11
  • 12
    • 0025142898 scopus 로고
    • Natural history of β-cell dysfunction in NIDDM
    • Leahy J. L. Natural history of β-cell dysfunction in NIDDM. Diabetes Care. 13:1990;992-1010.
    • (1990) Diabetes Care , vol.13 , pp. 992-1010
    • Leahy, J.L.1
  • 13
    • 0026511753 scopus 로고
    • Beta-cell dysfunction induced by chronic hyperglycaemia: Current ideas on the mechanism of the impaired glucose-induced insulin secretion
    • Leahy J. L., Bonner-Weir S., Weir G. C. Beta-cell dysfunction induced by chronic hyperglycaemia: Current ideas on the mechanism of the impaired glucose-induced insulin secretion. Diabetes Care. 15:1992;442-455.
    • (1992) Diabetes Care , vol.15 , pp. 442-455
    • Leahy, J.L.1    Bonner-Weir, S.2    Weir, G.C.3
  • 14
    • 0017179001 scopus 로고
    • Streptozotocin-induced pancreatic insulitis: New model of diabetes mellitus
    • Like A. A., Rossini A. A. Streptozotocin-induced pancreatic insulitis: new model of diabetes mellitus. Science. 193:1976;415-417.
    • (1976) Science , vol.193 , pp. 415-417
    • Like, A.A.1    Rossini, A.A.2
  • 15
    • 0019292063 scopus 로고
    • Androgen sensitization of streptozotocin-induced diabetes in mice
    • Maclaren N. K., Neufield M., McLaughlin J. V., Taylor G. Androgen sensitization of streptozotocin-induced diabetes in mice. Diabetes. 29:1980;710-716.
    • (1980) Diabetes , vol.29 , pp. 710-716
    • MacLaren, N.K.1    Neufield, M.2    McLaughlin, J.V.3    Taylor, G.4
  • 17
    • 0027193976 scopus 로고
    • GLUT2 expression and function in β-cells of GK rats with NIDDM. Dissociation between reductions in glucose transport and glucose-stimulated insulin secretion
    • Ohneda M., Johnson J. H., Inman L. R., Chen L., Suzuki K-I., Goto Y., Alam T., Ravazzola M., Orci L., Unger R. H. GLUT2 expression and function in β-cells of GK rats with NIDDM. Dissociation between reductions in glucose transport and glucose-stimulated insulin secretion. Diabetes. 42:1993;1065-1072.
    • (1993) Diabetes , vol.42 , pp. 1065-1072
    • Ohneda, M.1    Johnson, J.H.2    Inman, L.R.3    Chen, L.4    Suzuki, K-I.5    Goto, Y.6    Alam, T.7    Ravazzola, M.8    Orci, L.9    Unger, R.H.10
  • 19
    • 0000836601 scopus 로고
    • Roles of cytokines in IDDM pathogenesis and islet β-cell destruction
    • Rabinovitch A. Roles of cytokines in IDDM pathogenesis and islet β-cell destruction. Diabetes Rev. 1:1993;215-240.
    • (1993) Diabetes Rev. , vol.1 , pp. 215-240
    • Rabinovitch, A.1
  • 20
    • 0022896303 scopus 로고
    • Longitudinal study of first phase insulin release in the BB rat
    • Reddy S., Bibby N. J., Fisher S. L., Elliott R. B. Longitudinal study of first phase insulin release in the BB rat. Diabetologia. 29:1986;802-807.
    • (1986) Diabetologia , vol.29 , pp. 802-807
    • Reddy, S.1    Bibby, N.J.2    Fisher, S.L.3    Elliott, R.B.4
  • 21
    • 0023684290 scopus 로고
    • Ontogeny of islet cell antibodies, insulin autoantibodies and insulitis in the non-obese diabetic mouse
    • Reddy S., Bibby N. J., Elliott R. B. Ontogeny of islet cell antibodies, insulin autoantibodies and insulitis in the non-obese diabetic mouse. Diabetologia. 31:1988;322-328.
    • (1988) Diabetologia , vol.31 , pp. 322-328
    • Reddy, S.1    Bibby, N.J.2    Elliott, R.B.3
  • 22
    • 0031172694 scopus 로고    scopus 로고
    • Double-label immunofluorescence study of glutamic acid decarboxylase in the fetal and adult ovine pancreas by light and confocal microscopy: Evidence for predominant beta-cell coexpression
    • Reddy S., Elliott R. B., Poole C. A., Ross J. M. Double-label immunofluorescence study of glutamic acid decarboxylase in the fetal and adult ovine pancreas by light and confocal microscopy: evidence for predominant beta-cell coexpression. Gen. Comp. Endocrinol. 106:1997a;301-309.
    • (1997) Gen. Comp. Endocrinol. , vol.106 , pp. 301-309
    • Reddy, S.1    Elliott, R.B.2    Poole, C.A.3    Ross, J.M.4
  • 23
    • 0030905393 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase in pancreatic islets of the non-obese diabetic mouse: A light and confocal microscopic study of its ontogeny, co-localization and up-regulation following cytokine administration
    • Reddy S., Kaill S., Poole C. A., Ross J. Inducible nitric oxide synthase in pancreatic islets of the non-obese diabetic mouse: A light and confocal microscopic study of its ontogeny, co-localization and up-regulation following cytokine administration. Histochemical. J. 29:1997b;53-64.
    • (1997) Histochemical. J. , vol.29 , pp. 53-64
    • Reddy, S.1    Kaill, S.2    Poole, C.A.3    Ross, J.4
  • 24
    • 0029052170 scopus 로고
    • Low-dose streptozotocin causes diabetes in severe combined immunodeficient (SCID) mice without immune cell infiltration of the pancreatic islets
    • Reddy S., Wu D., Elliott R. B. Low-dose streptozotocin causes diabetes in severe combined immunodeficient (SCID) mice without immune cell infiltration of the pancreatic islets. Autoimmunity. 20:1995a;83-92.
    • (1995) Autoimmunity , vol.20 , pp. 83-92
    • Reddy, S.1    Wu, D.2    Elliott, R.B.3
  • 25
    • 0029063844 scopus 로고
    • Immunohistochemical analyses of pancreatic macrophages and CD4 and CD8 T cell subsets prior to and following diabetes in the NOD mouse
    • Reddy S., Wu D., Swinney C., Elliott R. B. Immunohistochemical analyses of pancreatic macrophages and CD4 and CD8 T cell subsets prior to and following diabetes in the NOD mouse. Pancreas. 11:1995b;16-25.
    • (1995) Pancreas , vol.11 , pp. 16-25
    • Reddy, S.1    Wu, D.2    Swinney, C.3    Elliott, R.B.4
  • 26
    • 0028604486 scopus 로고
    • STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells
    • Schnedl W. J., Ferber S., Johnson J. H., Newgard C. B. STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells. Diabetes. 43:1994;1326-1333.
    • (1994) Diabetes , vol.43 , pp. 1326-1333
    • Schnedl, W.J.1    Ferber, S.2    Johnson, J.H.3    Newgard, C.B.4
  • 27
    • 0021763962 scopus 로고
    • Free radical mechanisms in tissue injury
    • Slater T. F. Free radical mechanisms in tissue injury. Biochem. J. 222:1984;1-15.
    • (1984) Biochem. J. , vol.222 , pp. 1-15
    • Slater, T.F.1
  • 28
    • 0030444560 scopus 로고    scopus 로고
    • Destruction of rat pancreatic islet β-cells by cytokines involved aldehydes
    • Suarez-Pinson W. L., Strydnadka K., Rabinovitch A. Destruction of rat pancreatic islet β-cells by cytokines involved aldehydes. Endocrinology. 137:1996;5290-5296.
    • (1996) Endocrinology , vol.137 , pp. 5290-5296
    • Suarez-Pinson, W.L.1    Strydnadka, K.2    Rabinovitch, A.3
  • 30
    • 0027973020 scopus 로고
    • Preservation of GLUT2 expression in islet beta cells of Kilham Rat Virus (KRV)-infected diabetes-resistant BB/Wor rats
    • Stubbs M., Guberski D. L., Like A. A. Preservation of GLUT2 expression in islet beta cells of Kilham Rat Virus (KRV)-infected diabetes-resistant BB/Wor rats. Diabetologia. 37:1994;1186-1194.
    • (1994) Diabetologia , vol.37 , pp. 1186-1194
    • Stubbs, M.1    Guberski, D.L.2    Like, A.A.3
  • 31
    • 0026437459 scopus 로고
    • Molecular and cellular physiology of GLUT2 a high-Km facilitated diffusion glucose transporter
    • Thorens B. Molecular and cellular physiology of GLUT2 a high-Km facilitated diffusion glucose transporter. Int. Rev. Cytol. 137A:1992;209-238.
    • (1992) Int. Rev. Cytol. , vol.137 , pp. 209-238
    • Thorens, B.1
  • 32
    • 0025133270 scopus 로고
    • Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats
    • Thorens B., Weir G. C., Leahey J. L., Lodish H. F., Bonner-Weir S. Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats. Proc. Natl. Acad. Sci. USA. 87:1990;6492-6496.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6492-6496
    • Thorens, B.1    Weir, G.C.2    Leahey, J.L.3    Lodish, H.F.4    Bonner-Weir, S.5
  • 33
    • 0026656503 scopus 로고
    • The loss of GLUT2 expression by glucose-unresponsive β cells of db/db mice is reversible and is induced by the diabetic environment
    • Thorens B., Wu Y-J, Leahy J. L., Weir G. C. The loss of GLUT2 expression by glucose-unresponsive β cells of db/db mice is reversible and is induced by the diabetic environment. J. Clin. Invest. 90:1992;77-85.
    • (1992) J. Clin. Invest. , vol.90 , pp. 77-85
    • Thorens, B.1    Wu Y-J2    Leahy, J.L.3    Weir, G.C.4
  • 35
    • 0029609698 scopus 로고
    • Glucose transporter 2 expression: Prevention of streptozotocin-induced reduction in beta cells with 5-thio-D-glucose
    • Wang Z., Gleichmann H. Glucose transporter 2 expression: prevention of streptozotocin-induced reduction in beta cells with 5-thio-D-glucose. Exp. Clin. Endocrinol. 103:1995;83-87.
    • (1995) Exp. Clin. Endocrinol. , vol.103 , pp. 83-87
    • Wang, Z.1    Gleichmann, H.2
  • 36
    • 0025318609 scopus 로고
    • Streptozotocin interactions with pancreatic β cells and the induction of insulin-dependent diabetes
    • Wilson G. L., Leiter E. H. Streptozotocin interactions with pancreatic β cells and the induction of insulin-dependent diabetes. Curr. Top. Microbiol. Immunol. 156:1990;27-54.
    • (1990) Curr. Top. Microbiol. Immunol. , vol.156 , pp. 27-54
    • Wilson, G.L.1    Leiter, E.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.