Nitric oxide donor, NOC7, reveals biphasic effect on contractile force of isolated rat heart after global ischemia

Journal of Anesthesia

Volumn 22, Issue 3, 2008, Pages 229-235

  Hui, Yue ^a   Mochizuki, Toshiaki ^a   Kondo, Kazunao ^a   Umemura, Kazuo ^a   Sato, Shigehito ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cyclic nucleotides; Ischemia Reperfusion; Myocardial contractility; Nitric oxide (NO) donor; Phosphodiesterase inhibition; Post resuscitation period

Indexed keywords

3 (2 HYDROXY 1 METHYL 2 NITROSO HYDRAZINO) N METHYL 1 PROPANAMINE; BUFFER; CYCLIC AMP; CYCLIC GMP; NITRIC OXIDE DONOR; NOC 7;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRUG EFFECT; DRUG MECHANISM; ENZYME IMMUNOASSAY; HEART FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE ISCHEMIA; ISOLATED HEART; MALE; NONHUMAN; RAT; REPERFUSION; TISSUE HOMOGENATE;

5'-GUANYLIC ACID; ADENOSINE MONOPHOSPHATE; ANIMALS; GLUCOSE; HYDRAZINES; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; NITRIC OXIDE DONORS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RESEARCH DESIGN; TROMETHAMINE;

EID: 49649088873     PISSN: 09138668     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00540-008-0625-3     Document Type: Article

References (21)

1. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74:1124-1136.
2. American Heart Association. American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Part 7.5. Postresuscitation support. Circulation. 2005;112:IV84-IV88.
3. Sarkar D, Vallance P, Amirmansour C, Harding SE. Positive inotropic effects of NO donors in isolated guinea-pig and human cardiomyocytes independent of NO species and cyclic nucleotides. Cardiovasc Res. 2000;48:430-439.
4. Kojda G, Kottenberg K, Nix P, Schluter KD, Piper HM, Noack E. Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes. Circ Res. 1996;78:91-101.
5. Kelly RA, Balligand JL, Smith TW. Nitric oxide and cardiac function. Circ Res. 1996;79:363-380.
6. Okada H, Kurita T, Mochizuki T, Morita K, Sato S. The cardio-protective effect of dexmedetomidine on global ischaemia in isolated rat hearts. Resuscitation. 2007;74:538-545.
7. Vila-Petroff MG, Younes A, Egan J, Lakatta EG, Sollott SJ. Activation of distinct camp-dependent and cGMP-dependent pathways by nitric oxide in cardiac myocytes. Circ Res. 1999;84:1020-1031.
8. Moalem J, Weiss HR, Davidov T, Rodriguez R, Molino B, Lazar MJ, Scholz PM. Heart failure reduces both the effects and interaction between cyclic GMP and cyclic AMP. J Surg Res. 2006;134:300-306.
9. Kojda G, Kottenberg K. Regulation of basal myocardial function by NO. Cardiovasc Res. 1999;41:514-523.
10. Paulus WJ, Frantz S, Kelly RA. Nitric oxide and cardiac contractility in human heart failure: Time for reappraisal. Circulation. 2001;104:2260-2262.
11. Layland J, Solaro RJ, Shah AM. Regulation of cardiac contractile function by troponin I phosphorylation. Cardiovasc Res. 2005;66:12-21.
12. Rastaldo R, Pagliaro P, Cappello S, Penna C, Mancardi D, Westerhof N, Losano G. Nitric oxide and cardiac function. Life Sci. 2007;81:779-793.
13. Brown GC, Borutaite V. Nitric oxide and mitochondrial respiration in the heart. Cardiovasc Res. 2007;75:283-290.
14. Bryan NS, Rassaf T, Maloney RE, Rodriguez CM, Saijo F, Rodriguez JR, Feelisch M. Cellular targets and mechanisms of nitros(yl)ation: An insight into their nature and kinetics in vivo. Proc Natl Acad Sci U S A. 2004;101:4308-4313.
15. Hearse DJ, Bolli R. Reperfusion induced injury: Manifestations, mechanisms, and clinical relevance. Cardiovasc Res. 1992;26:101-108.
16. Piper HM, Garcia-Dorado D, Ovize M. A fresh look at reperfusion injury. Cardiovasc Res. 1998;38:291-300.
17. Maxwell SR, Lip GY. Reperfusion injury: A review of the pathophysiology, clinical manifestations and therapeutic options. Int J Cardiol. 1997;58:95-117.
18. Ferdinandy P, Danial H, Ambrus I, Rothery RA, Schulz R. Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure. Circ Res. 2000;87:241-247.
19. Amrani M, Chester AH, Jayakumar J, Schyns CJ, Yacoub MH. L-Arginine reverses low coronary reflow and enhances postischaemic recovery of cardiac mechanical function. Cardiovasc Res. 1995;30:200-204.
20. Hiramatsu T, Forbess JM, Miura T, Mayer JE Jr. Effects of L-arginine and L-nitro-arginine methyl ester on recovery of neonatal lamb hearts after cold ischemia. Evidence for an important role of endothelial production of nitric oxide. J Thorac Cardiovasc Surg. 1995;109:81-86; discussion 87.
21. Pabla R, Buda AJ, Flynn DM, Salzberg DB, Lefer DJ. Intracoronary nitric oxide improves postischemic coronary blood flow and myocardial contractile function. Am J Physiol. 1995;269:H1113-H1121.