Morphine-6-glucuronide: Potency and safety compared with morphine

Expert Opinion on Pharmacotherapy

Volumn 9, Issue 11, 2008, Pages 1955-1961

  van Dorp, Eveline L A ^a   Morariu, Aurora ^a   Dahan, Albert ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

opioid receptor; Analgesia; BBB; Blood brain barrier; M6G; Metabolites; Opioids; Pain; Pain relief

Indexed keywords

ANTIEMETIC AGENT; FENTANYL; MORPHINE; MORPHINE 6 GLUCURONIDE; NALOXONE; NARCOTIC ANALGESIC AGENT; PLACEBO;

ANALGESIC ACTIVITY; BIOEQUIVALENCE; CLINICAL TRIAL; COST BENEFIT ANALYSIS; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG DOSE TITRATION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; HUMAN; LIPOPHILICITY; LOADING DRUG DOSE; LOW DRUG DOSE; NONHUMAN; POSTMARKETING SURVEILLANCE; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; RESPIRATION DEPRESSION; REVIEW; SEDATION; SIDE EFFECT;

ANALGESICS, OPIOID; CLINICAL TRIALS, PHASE II AS TOPIC; CLINICAL TRIALS, PHASE III AS TOPIC; HUMANS; MORPHINE; MORPHINE DERIVATIVES; PAIN, POSTOPERATIVE; PATIENT COMPLIANCE; POSTOPERATIVE NAUSEA AND VOMITING;

EID: 49649085555     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.9.11.1955     Document Type: Review

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