Role of polyunsaturated fatty acids in the management of Egyptian children with autism

Clinical Biochemistry

Volumn 41, Issue 13, 2008, Pages 1044-1048

  Meguid, Nagwa A ^a   Atta, Hazem M ^b   Gouda, Amr S ^a   Khalil, Rehab O ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Autism; Efalex ; Fish oil; Polyunsaturated fatty acids; Tandem mass spectrometry

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; EFALEX; FISH OIL; LINOLEIC ACID; LINOLENIC ACID; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG;

ARTICLE; AUTISM; BLOOD SAMPLING; CHEMICAL ANALYSIS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; EGYPT; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ALPHA-LINOLENIC ACID; ARACHIDONIC ACID; AUTISTIC DISORDER; CHILD; CHILD BEHAVIOR; CHILD, PRESCHOOL; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS, UNSATURATED; FEMALE; FISH OILS; HUMANS; LINOLEIC ACID; MALE; PLANT OILS; TANDEM MASS SPECTROMETRY;

EID: 49549112474     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2008.05.013     Document Type: Article

References (23)

1. Wolanczyk T., Ostrowska-Galemba K., and Mikulska J. Features of autism, autistic traits, autism: retrospective analysis of clinical symptoms in children treated in the pediatric clinic. Psychiatria Polska 35 1 (2001) 59-69
2. Talat A. National study of autism in Saudi Arabia 2008, King Abdulaziz City for Science and Technology (2008)
3. Michael D., Gabriela H., and Emanuel T. Autism in the Haifa area - an epidemiological perspective. Isr Med Assoc J 3 3 (2001) 188-189
4. Fombonne E. Epidemiological surveys of autism and other pervasive developmental disorders: an update. J Autism Dev Disord 33 (2003) 365-383
5. Agostoni C., Riva E., Trojan S., Bellu R., and Giovannini M. Docosahexaenoic acid status and developmental quotient of healthy term infants. Lancet 345 8963 (Jun 1995) 1463-1468 10
6. Vancassel S., Durand G., Barthelemy, Lejeune B., Martineau J., Guilloteau D., Andres C., and Chalon S. Plasma fatty acids in autistic children. Prostaglandins Leuko Essen Fatty Acids 65 1 (2001) 1
7. Murphy M.G. Dietary fatty acids and membrane protein function. J Nutr Biochem 1 (1990) 68-78
8. Lauritzen L., Hansen H.S., and Jorgensen M.H. The essentiality of long-chain n-3 fatty acids in relation to development and function of the brain and retina. Prog Lipid Res 40 (2001) 1-94
9. Khan M.M., Evans D.R., Gunna V., Scheffer R.E., Parikh V.V., and Mahadik S.P. Reduced erythrocyte membrane essential fatty acids and increased lipid peroxides in schizophrenia at the never-medicated first-episode of psychosis and after years of treatment with antipsychotics. Schizophr Res. 58 1 (2002) 1-10
10. Burgess R.J., Stevens L., and Zhang W. Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder. Am J Clin Nutr 71 1 (2000) 327-330
11. Horrobin D.F. The membrane phospholipids hypothesis as a biochemical basis for the neurodevelopmental concept of schizophrenia. Schizophr Res 30 (1998) 193-208
12. Schopler E., Reichler R.J., and Renner B.R. The Childhood Autism Rating Scale (CARS) for diagnostic screening and classification of autism (1993), Irvington, New York
13. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edn (DSM-IV) (1994), APA, Washington, DC
14. Cavedon C.T., Bourdoux P., Mertens K., Van Thi H.V., Herremans N., De Laet C., and Goyens P. Age-related variations in acylcarnitine and free carnitine concentrations measured by tandem mass spectrometry. Clin Chem 51 4 (2005) 745-752
15. Zytkovicz T.H., Fitzgerald E.F., and Marsden D. Tandem mass spectrometric analysis for amino, organic, and fatty acid disorders in newborn dried blood spots. Clin Chem 47 (2001) 1945-1955
16. Bailey A., Phillips W., and Rutter M. Autism toward an integration of clinical, genetic, neuropsychological, and neurobiological perspectives. J Child Psychol Psychiatry 37 (1996) 89-126
17. Bell J., MacKinlay E., Dick J., MacDonald D., Boyle R., and Glen A. Essential fatty acids and phospholipase A2 in autistic spectrum disorders. Prostaglandins Leuko Essen Fatty Acids 71 (2004) 201-204
18. Mostafa G.A., EL-Gamal H.A., EL-Wakkad A.S., EL-Shyorbagy O.E., and Hamza M.A. Polyunsaturated fatty acids, carnitine and lactate as biological markers of brain energy in autistic children. Egyp J Child Neuropsych 2 2 (2005) 179-188
19. Bu B., Ashwood P., Harvey D., King I.B., Water J.V., and Jin L.W. Fatty acid compositions of red blood cell phospholipids in children with autism. Prostaglandins Leuko Essen Fatty acids 74 4 (2006) 215-221
20. Horrobin D.F., and Bennett C.N. New gene targets related to schizophrenia and other psychiatric disorders: enzymes, binding proteins and transport proteins involved in phospholipids and fatty acid metabolism. Prostaglandins Leuko Essen Fatty acids 60 (1999) 141-167
21. Bolton P., Powell J., Rutter M., Buckle V., Yates J.R., and Ishikawa B.Y. Autism, mental retardation, multiple exostoses and short stature in a female with 46,x,t(X;8)(p 22.13;q 22.1). Psychiat Genet 5 (1995) 51-55
22. Patrick L., and Salik R. The effect of essential fatty acid supplementation on language development and learning skills in autism and Asperger's syndrome. Autism - Asperger's Digest (Jan/Feb 2005) 36-37
23. Amminger G.P., Berger G.E., and Schafer M.R. Omega 3 fatty acids supplementation in children with autism: a double-blind randomized, placebo-controlled pilot study. Biol Psychiatry 61 4 (2007) 551-553