Novel anti-HIV peptides containing multiple copies of artificially designed heptad repeat motifs

Biochemical and Biophysical Research Communications

Volumn 374, Issue 4, 2008, Pages 767-772

  Shi, Weiguo ^a   Qi, Zhi ^b   Pan, Chungen ^b,c   Xue, Na ^b   Debnath, Asim K ^b   Qie, Jiankun ^a   Jiang, Shibo ^b   Liu, Keliang ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^b NEW YORK BLOOD CENTER   (United States)

^c PEKING UNIVERSITY   (China)

Author keywords

CHR; gp41; Heptad repeat; HIV fusion inhibitor; HIV 1; NHR; Peptide; Six helix bundle

Indexed keywords

ANTIVIRUS AGENT; ENFUVIRTIDE; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HYBRID PROTEIN;

ALPHA HELIX; AMINO ACID SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CELL FUSION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CELL FUSION; DRUG DESIGN; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; REPETITIVE SEQUENCES, AMINO ACID; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 49549112472     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.07.134     Document Type: Article

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