The evaluation of the immunomodulating properties of ERA-63 a pharmaceutical with estrogenic activity

Toxicology Letters

Volumn 180, Issue 3, 2008, Pages 196-201

  Janssen, G B ^a   Penninks, A H ^b   Knippels, L M J ^c   van Zijverden, M ^d   Spanhaak, S ^e  

^a NV ORGANON   (Netherlands)

^b TNO   (Netherlands)

^c NUMICO RESEARCH   (Netherlands)

^d NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^e JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Ethinyl estradiol; Host resistance; Immunotoxicity; Listeria monocytogenes; PFC; Plaque forming cell assay; T cell dependent antibody response

Indexed keywords

BILIRUBIN; ERA 63; ETHINYLESTRADIOL; GAMMA GLUTAMYLTRANSFERASE; IMMUNOMODULATING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BILIRUBIN BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG MEGADOSE; DRUG SCREENING; ESTROGEN ACTIVITY; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; IMMUNOMODULATION; LISTERIA MONOCYTOGENES; LOW DRUG DOSE; MALE; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RAT; TESTIS WEIGHT; THYMUS;

ANIMALS; ANTIBODY FORMATION; BODY WEIGHT; ESTROGENS; ETHINYL ESTRADIOL; FEMALE; HEMOLYTIC PLAQUE TECHNIQUE; IMMUNOLOGIC FACTORS; LISTERIA INFECTIONS; MALE; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RISK ASSESSMENT; T-LYMPHOCYTES;

LISTERIA MONOCYTOGENES; RATTUS;

EID: 49549094708     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.06.857     Document Type: Article

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