Lensless high-resolution on-chip optofluidic microscopes for Caenorhabditis elegans and cell imaging

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 31, 2008, Pages 10670-10675

  Cui, Xiquan ^a   Lee, Lap Man ^b   Heng, Xin ^a   Zhong, Weiwei ^c   Sternberg, Paul W ^c   Psaltis, Demetri ^a,d   Yang, Changhuei ^a,b,e  

^a California Institute of Technology   (United States)

^b California Institute of Technology   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d EPFL   (Switzerland)

^e NONE   (United States)

Author keywords

Microfluidic; Optofluidic microscopy; Phenotype characterization

Indexed keywords

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; GENETIC ANALYSIS; MICROARRAY ANALYSIS; MICROFLUIDIC ANALYSIS; MICROSCOPY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; CAENORHABDITIS ELEGANS; CELLS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROSCOPY; PHENOTYPE;

CAENORHABDITIS ELEGANS;

EID: 49449099066     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804612105     Document Type: Article

References (29)

1. Whitesides GM (2006) The origins and the future of microfluidics. Nature 442:368-373.
2. El-Ali J, Sorger PK, Jensen KF (2006) Cells on chips. Nature 442:403-411.
3. Garcia-Sucerquia J, et al. (2006) Digital in-line holographic microscopy. Appl Opt 45:836-850.
4. Lange D, Storment CW, Conley CA, Kovacs GTA (2005) A microfluidic shadow imaging system for the study of the nematode Caenorhabditis elegans in space. Sensors Actuators B 107:904-914.
5. Ozcan A, Demirci U. Ultra wide-field lens-free monitoring of cells on-chip. Lab Chip- Miniaturisation for Chemistry and Biology (2007), 8(1), 98-106, DOI: 10.1039/b713695a
6. Heng X, et al. (2006) Optofluidic microscopy - A method for implementing a high resolution optical microscope on a chip. Lab Chip 6:1274-1276.
7. Courjon D (2003) Near-Field Microscopy and Near-Field Optics (Imperial College Press, London).
8. Bochner BR (2003) New technologies to assess genotype-phenotype relationships. Nat Rev Genet 4:309-314.
9. Zhong WW, Sternberg PW (2006) Genome-wide prediction of C-elegans genetic interactions. Science 311:1481-1484.
10. Savage C, et al. (1996) Caenorhabditis elegans genes sma2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components. Proc Natl Acad Sci USA 93:790-794.
11. Gilleard JS, Barry JD, Johnstone IL (1997) cis regulatory requirements for hypodermal cell-specific expression of the Caenorhabditis elegans cuticle collagen gene dpy-7. Mol Cell Biol 17:2301-2311.
12. Savage-Dunn C, et al. (2000) SMA-3 Smad has specific and critical functions in DBL-1/SMA-6 TGF β-related signaling. Dev Biol 223:70-76.
13. Beebe DJ, Mensing GA, Walker GM (2002) Physics and applications of microfluidics in biology. Annu Rev Biomed Eng 4:261-286.
14. Hughes MP (2003) Nanoelectromechanics in Engineering and Biology (CRC Press, Boca Raton, FL), 1st Ed.
15. Grossman PD, Colburn JC (1992) Capilliary Electrophoresis (Academic, London), 1st Ed.
16. Probstein RF (2003) Physicochemical Hydrodynamics (Wiley InterScience, New York), 2nd Ed.
17. Park JH, Hwang DK, Lee J, Im S, Kim E (2007) Studies on poly(methyl methacrylate) dielectric layer for field effect transistor: Influence of polymer tacticity. Thin Solid Films 515:4041-4044.
18. Jones AW, Bland-Hawthorn J (1995) Towards a general definition for spectroscopic resolution. Astronomical Data Analysis Software and Systems IV, Astronomical Society of the Pacific Conference Series (Astronomical Society of the Pacific, Provo, UT), Vol 77, pp 503-507.
19. Heng X, et al. (2006) Characterization of light collection through a subwavelength aperture from a point source. Opt Express 14:10410-10425.
20. Cui W, et al. (2003) Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome. Clin Infect Dis 37:857-859.
21. Marrazzo JM, et al. (1997) Community-based urine screening for Chlamydia trachomatis with a ligase chain reaction assay. Ann Intern Med 127:796-803.
22. Carroll KC, et al. (1994) Laboratory evaluation of urinary-tract infections in an ambulatory clinic. Am J Clinical Pathol 101:100-103.
23. McCowage GB, et al. (1998) Multiparameter-fluorescence activated cell sorting analysis of retroviral vector gene transfer into primitive umbilical cord blood cells. Exp Hematol 26:288-298.
24. Buchstaller J, et al. (2004) Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells. J Neurosci 24:2357-2365.
25. Fujiwara T, et al. (1994) Therapeutic effect of a retroviral wild-type P53 expression vector in an orthotopic lung-cancer model. J Natl Cancer Inst 86:1458-1462.
26. Fox SB, et al. (1993) Relationship of endothelial-cell proliferation to tumor vascularity in human breast-cancer. Cancer Res 53:4161-4163.
27. Perlman ZE, et al. (2004) Multidimensional drug profiling by automated microscopy. Science 306:1194-1198.
28. Sulston JE, Hodgkin JA (1988) The Nematode Caenorhabditis elegans (Cold Spring Harbor Lab Press, Cold spring Harbor, NY).
29. Hu S, et al. (2003) Cross-linked coatings for electrophoretic separations in poly(dimethylsiloxane) microchannels. Electrophoresis 24:3679-3688.