Validated comprehensive analytical method for quantification of coenzyme A activated compounds in biological tissues by online solid-phase extraction LC/MS/MS

Analytical Chemistry

Volumn 80, Issue 15, 2008, Pages 5736-5742

  Magnes, Christoph ^a   Suppan, Maria ^a   Pieber, Thomas R ^a,b   Moustafa, Tarek ^b   Trauner, Michael ^b   Haemmerle, Guenter ^c   Sinner, Frank M ^a  

^a JOANNEUM RESEARCH   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; ARSENIC COMPOUNDS; CENTRIFUGATION; CHLORINE COMPOUNDS; EXTRACTION; FATTY ACIDS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HISTOLOGY; HOMOGENIZATION METHOD; INJECTION (OIL WELLS); LIVER; ORGANIC COMPOUNDS; ORGANIC SOLVENTS; SOLAR RADIATION; STANDARDS;

ACTIVATED COMPOUNDS; ANALYTICAL METHODS; BIOLOGICAL TISSUES; COENZYME A; INTERNAL STANDARDS; LC/MS/MS; LONG-CHAIN ACYL-COA; LOWER LIMIT OF QUANTIFICATION; MASS DETERMINATION; MATRIX EFFECTS; METHOD VALIDATIONS; MOUSE LIVER; MOUSE TISSUES; PHYSIOLOGICAL LEVELS; RAT LIVERS; SAMPLE PREPARATIONS; SKELETAL MUSCLES; SOLID-PHASE EXTRACTION; WHITE ADIPOSE TISSUE;

TISSUE;

COENZYME A; FATTY ACID; LONG CHAIN ACYL COENZYME A DEHYDROGENASE; ORGANIC SOLVENT;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; DIAGNOSTIC ACCURACY; ENZYME ACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIVER; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; ONLINE ANALYSIS; QUANTITATIVE ANALYSIS; RAT; SKELETAL MUSCLE; SOLID PHASE EXTRACTION; VALIDATION STUDY; WHITE ADIPOSE TISSUE;

CHEMISTRY, ANALYTICAL; CHROMATOGRAPHY, LIQUID; COENZYME A; CROWN ETHERS; ELECTROCHEMISTRY; OLIGOPEPTIDES; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 49449085322     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac800031u     Document Type: Article

References (19)

1. Luo, Z.; Saha, A. K.; Xiang, X.; Ruderman, N. B. Trends Pharmacol. Sci. 2005, 26, 69-76.
2. Ruderman, N. B.; Saha, A. K. Obesity (Silver Spring) 2006, 14, 25S-33S.
3. Folmes, C. D.; Lopaschuk, G. D. Cardiovasc. Res. 2007, 73, 278-87.
4. Shulman, G. I. J. Clin. Invest 2000, 106, 171-76.
5. An, J.; Muoio, D. M.; Shiota, M.; Fujimoto, Y.; Cline, G. W.; Shulman, G. I.; Koves, T. R.; Stevens, R.; Millington, D.; Newgard, C. B. Nat. Med. 2004, 10, 268-74.
6. Ellis, B. A.; Poynten, A.; Lowy, A. J.; Furler, S. M.; Chisholm, D. J.; Kraegen, E. W.; Cooney, G. J. Am. J. Physiol. Endocrinol. Metab. 2000, 279, E554-E560.
7. Gregersen, N.; Bross, P.; Andresen, B. S. Eur. J. Biochem. 2004, 271, 470-82.
8. Roe, C. R.; Millington, D. S.; Maltby, D. A.; Kinnebrew, P. J. Pediatr. 1986, 108, 13-18.
9. Knights, K. M.; Drogemuller, C. J. Curr. Drug Metab. 2000, 1, 49-66.
10. Boelsterli, U. A. Curr. Drug Metab. 2002, 3, 439-50.
11. Magnes, C.; Sinner, F. M.; Regittnig, W.; Pieber, T. R. Anal. Chem. 2005, 77, 2889-94.
12. Hankin, J. A.; Murphy, R. C. Int. J. Mass Spectrom. Ion Processes 1997, 165/166, 467-74.
13. Gao, L.; Chiou, W.; Tang, H.; Cheng, X.; Camp, H. S.; Burns, D. J. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. In press.
14. Hughes, N.; Winnik, W.; Dunyach, J. J.; Amad, M.; Splendore, M.; Paul, G. J. Mass Spectrom. 2003, 38, 743-51.
15. Paul, G.; Winnik, W.; Hughes, N.; Schweingruber, H.; Heller, R.; Schoen, A. Rapid Commun. Mass Spectrom. 2003, 17, 561-68.
16. de Rijke, E.; Ruisch, B. J.; Bouter, N.; Konig, T. Mol. Nutr. Food Res. 2006, 50, 351-55.
17. Marull, M.; Rochat, B. J. Mass Spectrom. 2006, 41, 390-404.
18. Bristow, A. W.; Webb, K. S. J. Am. Soc. Mass Spectrom. 2003, 14, 1086-98.
19. Marull, M.; Rochat, B. J. Mass Spectrom. 2006, 41, 390-404.