Gender and body size affect the response of erythrocyte folate to folic acid treatment

Journal of Nutrition

Volumn 138, Issue 8, 2008, Pages 1456-1461

  Winkels, Renate M ^c   Brouwer, Ingeborg A ^a   Verhoef, Petra ^c   Van Oort, Floor V A ^b   Durga, Jane ^c   Katan, Martijn B ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID;

ADULT; AGED; ARTICLE; BODY SIZE; CLINICAL TRIAL; DIET SUPPLEMENTATION; DIETARY INTAKE; DRUG ERYTHROCYTE LEVEL; FEMALE; HUMAN; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MALE; SEX DIFFERENCE;

EID: 49449083792     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/138.8.1456     Document Type: Article

References (36)

1. Dietrich M, Brown CJP, Block G. The effect of folate fortification of cereal-grain products on blood folate status, dietary folate intake, and dietary folate sources among adult non-supplement users in the United States. J Am Coll Nutr. 2005;24:266-74.
2. de Bree A, van Dusseldorp M, Brouwer IA, van het Hof KH, Steegers-Theunissen RP. Folate intake in Europe: recommended, actual and desired intake. Eur J Clin Nutr. 1997;51:643-60.
3. Ganji V, Kafai MR. Trends in serum folate, RBC folate, and circulating total homocysteine concentrations in the United States: analysis of data from National Health and Nutrition Examination Surveys, 1988-1994, 1999-2000, and 2001-2002. J Nutr. 2006;136:153-8.
4. Verhoef P, Meleady R, Daly LE, Graham IM, Robinson K, Boers GH. Homocysteine, vitamin status and risk of vascular disease; effects of gender and menopausal status. European COMAC Group. Eur Heart J. 1999;20:1234-44.
5. Pfeiffer CM, Johnson CL, Jain RB, Yetley EA, Picciano MF, Rader JI, Fisher KD, Mulinare J, Osterloh JD. Trends in blood folate and vitamin B-12 concentrations in the United States, 1988 2004. Am J Clin Nutr. 2007;86:718-27.
6. Institute of Medicine. Folate. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Washington: National Academy Press; 2000. p. 196-305.
7. O'Keefe CA, Bailey LB, Thomas EA, Hofler SA, Davis BA, Cerda JJ, Gregory JF III. Controlled dietary folate affects folate status in nonpregnant women. J Nutr. 1995;125:2717-25.
8. Sauberlich HE, Kretsch MJ, Skala JH, Johnson HL, Taylor PC. Folate requirement and metabolism in nonpregnant women. Am J Clin Nutr. 1987;46:1016-28.
9. Committee on Medical Aspects of Food and Nutrition Policy (COMA). Dietary reference values for food energy and nutrients for the United Kingdom. London (UK): Department of Health; 1991.
10. Health Council of the Netherlands. Dietary reference intakes: Vitamin B6, folic acid and vitamin B12. The Hague: Health Council of the Netherlands; 2003. Report No.: publication no. 2003/04.
11. Herbert V. Recommended dietary intakes (RDI) of folate in humans. Am J Clin Nutr. 1987;45:661-70.
12. Olson JA. Recommended dietary intakes (RDI) of vitamin A in humans. Am J Clin Nutr. 1987;45:704-16.
13. Institute of Medicine. Vitamin C. Dietary reference intakes for vitamin C, vitamin E, selenium and carotenoids. Washington: National Academy Press; 2000. p. 35-58.
14. Blanchard J. Effects of gender on vitamin C pharmacokinetics in man. J Am Coll Nutr. 1991;10:453-9.
15. Blanchard J. Depletion and repletion kinetics of vitamin C in humans. J Nutr. 1991;121:170-6.
16. Health Council of the Netherlands. Risks of folic acid fortification. The Hague: Health Council of the Netherlands; 2000. Report No.: publication no. 2000/21.
17. Institute of Medicine. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Washington: National Academy Press; 2000.
18. Institute of Medicine. Dietary reference intakes for vitamin a, vitamin k, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington: National Academy Press; 2000.
19. Morgan DJ, Bray KM. Lean body mass as a predictor of drug dosage. Implications for drug therapy. Clin Pharmacokinet. 1994;26:292-307.
20. Durga J, van Boxtel MPJ, Schouten EG, Kok FJ, Jolles J, Katan MB, Verhoef P. Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial. Lancet. 2007;369:208-16.
21. Durga J, Verhoef P, Anteunis LJ, Schouten E, Kok FJ. Effects of folic acid supplementation on hearing in older adults: a randomized, controlled trial. Ann Intern Med. 2007;146:1-9.
22. van Oort FV, Melse-Boonstra A, Brouwer IA, Clarke R, West CE, Katan MB, Verhoef P. Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study. Am J Clin Nutr. 2003;77:1318-23.
23. Green B, Duffull S. Caution when lean body weight is used as a size descriptor for obese subjects. Clin Pharmacol Ther. 2002;72:743-4.
24. Green B, Duffull SB. What is the best size descriptor to use for pharmacokinetic studies in the obese? Br J Clin Pharmacol. 2004;58:119-33.
25. Sawyer M, Ratain MJ. Body surface area as a determinant of pharmacokinetics and drug dosing. Invest New Drugs. 2001;19:171-7.
26. Ditlevsen S, Christensen U, Lynch J, Damsgaard MT, Keiding N. The mediation proportion: a structural equation approach for estimating the proportion of exposure effect on outcome explained by an intermediate variable. Epidemiology. 2005;16:114-20.
27. Wald NJ, Law MR, Morris JK, Wald DS. Quantifying the effect of folic acid. Lancet. 2001;358:2069-73.
28. Coppen A, Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial. J Affect Disord. 2000;60:121-30.
29. van der Griend R, Haas FJ, Biesma DH, Duran M, Meuwissen OJ, Banga JD. Combination of low-dose folic acid and pyridoxine for treatment of hyperhomocysteinaemia in patients with premature arterial disease and their relatives. Atherosclerosis. 1999;143:177-83.
30. Bailey LB, Cerda JJ, Bloch BS, Busby MJ, Vargas L, Chandler CJ, Halsted CH. Effect of age on poly- and monoglutamyl folacin absorption in human subjects. J Nutr. 1984;114:1770-6.
31. Wald DS, Bishop L, Wald NJ, Law M, Hennessy E, Weir D, McPartlin J, Scott J. Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med. 2001;161:695-700.
32. Harvey LJ, Armah CN, Dainty JR, Foxall RJ, Lewis DJ, Langford NJ, Fairweather-Tait SJ. Impact of menstrual blood loss and diet on iron deficiency among women in the UK. Br J Nutr. 2005;94:557-64.
33. Brouwer IA, Dusseldorp MV, West CE, Steegers-Theunissen RPM. Bioavailability and bioefficacy of folate and folic acid in man. Nutr Res Rev. 2001;14:267-94.
34. Winkels RM, Brouwer IA, Siebelink E, Katan MB, Verhoef P. Bioavailability of food folates is 80% of that of folic acid. Am J Clin Nutr. 2007;85:465-73.
35. Bentley TG, Willett WC, Weinstein MC, Kuntz KM. Population-level changes in folate intake by age, gender, and race/ethnicity after folic acid fortification. Am J Public Health. 2006;96:2040-7.
36. van de Rest O, Durga J, Verhoef P, Melse-Boonstra A, Brants HAM. Validation of a food frequency questionnaire to assess folate intake of dutch elderly people. Br J Nutr. 2007;98:1014-20.