Accelerated diabetic neuropathy in axons without neurofilaments

Brain

Volumn 127, Issue 10, 2004, Pages 2193-2200

  Zochodne, Douglas W ^a   Sun, Hong Shuo ^a   Cheng, Chu ^a   Eyer, Joel ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITÉ D'ANGERS   (France)

Author keywords

Axonal atrophy; Conduction velocity; Diabetes mellitus

Indexed keywords

HYBRID PROTEIN; INSULIN; STREPTOZOCIN; NEUROFILAMENT PROTEIN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CAUDATE NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETIC NEUROPATHY; DISEASE COURSE; EXPERIMENTAL DIABETES MELLITUS; HYPERGLYCEMIA; MOTOR NERVE; MOUSE; NERVE CONDUCTION; NERVE FIBER; NEUROFILAMENT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE; TRANSGENIC MOUSE; TREATMENT OUTCOME; ANIMAL; ATROPHY; MYELINATED NERVE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SURAL NERVE; TIBIAL NERVE;

ACTION POTENTIALS; ANIMALS; ATROPHY; AXONS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; MICE; MICE, TRANSGENIC; NERVE FIBERS, MYELINATED; NEURAL CONDUCTION; NEUROFILAMENT PROTEINS; SURAL NERVE; TIBIAL NERVE;

EID: 4944263780     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awh251     Document Type: Article

References (41)

1. Auer RN. Automated nerve fibre size and myelin sheath measurement using microcomputer-based digital image analysis: theory, method and results. J Neurosci Methods 1994; 51: 229-38.
2. Brooker GJ, Kalloniatis M, Russo VC, Murphy M, Werther GA, Bartlett PF. Endogenous IGF-1 regulates the neuronal differentiation of adult stem cells. J Neurosci Res 2000; 59: 332-41.
3. Brussee V, Buchan AM, Zochodne DW. Do insulin and IGF-1 target neurons in experimental diabetes? [abstract]. Soc Neurosci Abstr 2001; 31: 55.
4. Elder GA, Friedrich VL Jr, Margita A, Lazzarini RA. Age-related atrophy of motor axons in mice deficient in the mid-sized neurofilament subunit. J Cell Biol 1999; 146: 181-92.
5. Eyer J, Peterson A. Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-beta- galactosidase fusion protein. Neuron 1994; 12: 389-405.
6. Fernyhough P, Gallagher A, Averill SA, Priestley JV, Hounsom L, Patel J, et al. Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy. Diabetes 1999; 48: 881-9.
7. Garcia ML, Lobsiger CS, Shah SB, Deerinck TJ, Crum J, Young D, et al. NF-M is an essential target for the myelin-directed 'outside-in' signaling cascade that mediates radial axonal growth. J Cell Biol 2003; 163: 1011-20.
8. Huang TJ, Price SA, Chilton L, Calcutt NA, Tomlinson DR, Verkhratsky A, et al. Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia. Diabetes 2003; 52: 2129-36.
9. Ishii DN. Insulin and related neurotrophic factors in diabetic neuropathy. Diabet Med 1993; 10 Suppl 2: 14S-5S.
10. Ishii DN. Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy. Brain Res Brain Res Rev 1995; 20: 47-67.
11. Kurihara S, Hakuno F, Takahashi S. Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway. Endocr J 2000; 47: 739-51.
12. Lackey BR, Gray SL, Henricks DM. Actions and interactions of the IGF system in Alzheimer's disease: review and hypotheses. Growth Horm IGF Res 2000; 10: 1-13.
13. Lariviere RC, Julien JP. Functions of intermediate filaments in neuronal development and disease. J Neurobiol 2004; 58: 131-48.
14. McLean WG. The role of the axonal cytoskeleton in diabetic neuropathy. Neurochem Res 1997; 22: 951-6.
15. Medori R, Autilio-Gambetti L, Monaco S, Gambetti P. Experimental diabetic neuropathy: impairment of slow transport with changes in axon cross-sectional area. Proc Natl Acad Sci USA 1985; 82: 7716-20.
16. Medori R, Autilio-Gambetti L, Jenich H, Gambetti P. Changes in axon size and slow axonal transport are related in experimental diabetic neuropathy. Neurology 1988a; 38: 597-601.
17. Medori R, Jenich H, Autilio-Gambetti L, Gambetti P. Experimental diabetic neuropathy: similar changes of slow axonal transport and axonal size in different animal models. J Neurosci 1988b; 8: 1814-21.
18. Ng TF, Lee FK, Song ZT, Calcutt NA, Lee AY, Chung SS, et al. Effects of sorbitol dehydrogenase deficiency on nerve conduction in experimental diabetic mice. Diabetes 1998; 47: 961-6.
19. O'Kusky JR, Ye P, D'Ercole AJ. Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development. J Neurosci 2000; 20: 8435-42.
20. Patti ME, Sun XJ, Bruening JC, Araki E, Lipes MA, White MF, et al. 4PS/insulin receptor substrate (IRS)-2 is the alternative substrate of the insulin receptor in IRS-1-deficient mice. J Biol Chem 1995; 270: 24670-3.
21. Rao MV, Garcia ML, Miyazaki Y, Gotow T, Yuan A, Mattina S, et al. Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport. J Cell Biol 2002; 158: 681-93.
22. Recio-Pinto E, Ishii DN. Effects of insulin, insulin-like growth factor-II and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells. Brain Res 1984; 302: 323-34.
23. Recio-Pinto E, Rechler MM, Ishii DN. Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons. J Neurosci 1986; 6: 1211-9.
24. Russell JW, Sullivan KA, Windebank AJ, Herrmann DN, Feldman EL. Neurons undergo apoptosis in animal and cell culture models of diabetes. Neurobiol Dis 1999; 6: 347-63.
25. Sayers NM, Beswick LJ, Middlemas A, Calcutt NA, Mizisin AP, Tomlinson DR, et al. Neurotrophin3 prevents the proximal accumulation of neurofilament proteins in sensory neurons of Streptozocin-induced diabetic rats, Diabetes 2003; 52: 2372-2380.
26. Schmelzer JD, Low PA. Electrophysiological studies on the effect of age on caudal nerve of the rat. Exp Neurol 1987; 96: 612-20.
27. Schmidt RE, Dorsey D, Parvin CA, Beaudet LN, Plurad SB, Roth KA. Dystrophic axonal swellings develop as a function of age and diabetes in human dorsal root ganglia. J Neuropathol Exp Neurol 1997; 56: 1028-43.
28. Scott JN, Clark AW, Zochodne DW. Neurofilament and tubulin gene expression in progressive experimental diabetes: failure of synthesis and export by sensory neurons. Brain 1999; 122: 2109-18.
29. Sima AAF. Metabolic alterations of peripheral nerve in diabetes. Semin Neurol 1996; 16: 129-37.
30. Singhal A, Cheng C, Sun H, Zochodne DW. Near nerve local insulin prevents conduction slowing in experimental diabetes. Brain Res 1997; 763: 209-14.
31. Sternberger LA, Sternberger NH. Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc Natl Acad Sci USA 1983; 80: 6126-30.
32. Sugimoto K, Murakawa Y, Zhang W, Xu G, Sima AA. Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms. Diabetes Metab Res Rev 2000; 16: 354-63.
33. Sugimoto K, Murakawa Y, Sima AA. Expression and localization of insulin receptor in rat dorsal root ganglion and spinal cord. J Peripher Nerv Syst 2002; 7: 44-53.
34. Tu PH, Robinson KA, de Snoo F, Eyer J, Peterson A, Lee VM, et al. Selective degeneration of Purkinje cells with Lewy body-like inclusions in aged NFHLACZ transgenic mice. J Neurosci 1997; 17: 1064-74.
35. White MF. Insulin signaling in health and disease. Science 2003; 302: 1710-1.
36. White MF, Yenush L. The IRS-signaling system: a network of docking proteins that mediate insulin and cytokine action. Curr Top Microbiol Immunol 1998; 228: 179-208.
37. Williamson TL, Bruijn LI, Zhu Q, Anderson KL, Anderson SD, Julien JP, et al. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proc Natl Acad Sci USA 1998; 95: 9631-6.
38. Yagihashi S. Axonal cytoskeleton and diabetic neuropathy. Diabet Med 1993; 10 Suppl 2: 107S-9S.
39. Zochodne DW, Ho LT. The influence of indomethacin and guanethidine on experimental streptozotocin diabetic neuropathy. Can J Neurol Sci 1992a; 19: 433-41.
40. Zochodne DW, Ho LT. Normal blood flow but lower oxygen tension in diabetes of young rats: microenvironment and the influence of sympathectomy. Can J Physiol Pharmacol 1992b; 70: 651-9.
41. Zochodne DW, Cheng C, Sun H. Diabetes increases sciatic nerve susceptibility to endothelin-induced ischemia. Diabetes 1996; 45: 627-32.