Key differences in molecular complexes of the cholecystokinin receptor with structurally related peptide agonist, partial agonist, and antagonist

Molecular Pharmacology

Volumn 66, Issue 3, 2004, Pages 545-552

  Arlander, Sonnet J H ^a   Dong, Maoqing ^a   Ding, Xi Qin ^a,b   Pinon, Delia I ^a   Miller, Laurence J ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ DERIVATIVE; CHOLECYSTOKININ OCTAPEPTIDE; CHOLECYSTOKININ RECEPTOR BLOCKING AGENT; CHOLECYSTOKININ RECEPTOR STIMULATING AGENT; DEXTRO TYROSYLGLYCYLCHOLECYSTOKININ OCTAPEPTIDE[28,31 NORLEUCINE]; DEXTRO TYROSYLGLYCYLCHOLECYSTOKININ PHENYLETHYL ESTER[28,31 NORLEUCINE, 30 DEXTRO TRYPTOPHAN]; DEXTRO TYROSYLGLYCYLCHOLECYSTOKININ PHENYLETHYL ESTER[28,31 NORLEUCINE]; PARTIAL AGONIST; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG POTENCY; DRUG RECEPTOR BINDING; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SULFATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHO CELLS; CHOLECYSTOKININ; CRICETINAE; LIGANDS; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOTOAFFINITY LABELS; PROTEIN CONFORMATION; RECEPTORS, CHOLECYSTOKININ; TYROSINE;

EID: 4944226721     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.001396     Document Type: Article

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