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Volumn 84, Issue 10, 2004, Pages 1339-1351

Chromosome 12, frequently deleted in human pancreatic cancer, may encode a tumor-suppressor gene that suppresses angiogenesis

Author keywords

Angiogenesis; Chromosome 12; Pancreatic cancer

Indexed keywords

DNA; MESSENGER RNA;

EID: 4944220115     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700160     Document Type: Article
Times cited : (15)

References (45)
  • 1
    • 0033559933 scopus 로고    scopus 로고
    • Estimates of the worldwide incidence of 25 major cancers in 1990
    • Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer 1999;80:827-841.
    • (1999) Int J Cancer , vol.80 , pp. 827-841
    • Parkin, D.M.1    Pisani, P.2    Ferlay, J.3
  • 2
    • 0025652618 scopus 로고
    • The detection and prognosis of small pancreatic carcinoma
    • Ariyama J, Suyama M, Ogawa K, et al. The detection and prognosis of small pancreatic carcinoma. Int J Pancreatol 1990;7:37-47.
    • (1990) Int J Pancreatol , vol.7 , pp. 37-47
    • Ariyama, J.1    Suyama, M.2    Ogawa, K.3
  • 3
    • 0028239486 scopus 로고
    • Suppression of tumorigenicity of human prostate cancer cells by introduction of human chromosome del(12)(q13)
    • Beruhe NG, Speevak MD, Chevrette M. Suppression of tumorigenicity of human prostate cancer cells by introduction of human chromosome del(12)(q13). Cancer Res 1994;54:3077-3081.
    • (1994) Cancer Res , vol.54 , pp. 3077-3081
    • Beruhe, N.G.1    Speevak, M.D.2    Chevrette, M.3
  • 4
    • 0032529268 scopus 로고    scopus 로고
    • Identification of a novel metastasis-suppressor region on human chromosome 12
    • Luu HH, Zagaja GP, Dubauskas Z, et al. Identification of a novel metastasis-suppressor region on human chromosome 12. Cancer Res 1998;58:3561-3565.
    • (1998) Cancer Res , vol.58 , pp. 3561-3565
    • Luu, H.H.1    Zagaja, G.P.2    Dubauskas, Z.3
  • 5
    • 0024390277 scopus 로고
    • Clonal allele loss in gastrointestinal cancers
    • Fey MF, Hesketh C, Wainscoat JS, et al. Clonal allele loss in gastrointestinal cancers. Br J Cancer 1989;59:750-754.
    • (1989) Br J Cancer , vol.59 , pp. 750-754
    • Fey, M.F.1    Hesketh, C.2    Wainscoat, J.S.3
  • 6
    • 0025807514 scopus 로고
    • Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas
    • Sano T, Tsujino T, Yoshida K, et al. Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas. Cancer Res 1991;51:2926-2931.
    • (1991) Cancer Res , vol.51 , pp. 2926-2931
    • Sano, T.1    Tsujino, T.2    Yoshida, K.3
  • 7
    • 0029088784 scopus 로고
    • Allelic imbalance in gastric cancer: An affected site on chromosome arm 3p
    • Schneider BG, Pulitzer DR, Brown RD, et al. Allelic imbalance in gastric cancer: an affected site on chromosome arm 3p. Genes Chromosomes Cancer 1995;13:263-271.
    • (1995) Genes Chromosomes Cancer , vol.13 , pp. 263-271
    • Schneider, B.G.1    Pulitzer, D.R.2    Brown, R.D.3
  • 8
    • 0026454815 scopus 로고
    • Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors
    • Murty VV, Houldsworth J, Baldwin S, et al. Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors. Proc Natl Acad Sci USA 1992;89:11006-11010.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11006-11010
    • Murty, V.V.1    Houldsworth, J.2    Baldwin, S.3
  • 9
    • 0029854322 scopus 로고    scopus 로고
    • Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: Identification of a 1-cM region of common allelic loss
    • Kimura M, Abe T, Sunamura M, et al. Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: identification of a 1-cM region of common allelic loss. Genes Chromosomes Cancer 1996;17:88-93.
    • (1996) Genes Chromosomes Cancer , vol.17 , pp. 88-93
    • Kimura, M.1    Abe, T.2    Sunamura, M.3
  • 10
    • 0030919992 scopus 로고    scopus 로고
    • Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma
    • Fukushige S, Waldman FM, Kimura M, et al. Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma. Genes Chromosomes Cancer 1997;19:161-169.
    • (1997) Genes Chromosomes Cancer , vol.19 , pp. 161-169
    • Fukushige, S.1    Waldman, F.M.2    Kimura, M.3
  • 11
    • 0036262452 scopus 로고    scopus 로고
    • Detailed genomic mapping and expression analyses of 12p amplifications in pancreatic carcinomas reveal a 3.5-Mb target region for amplification
    • Heidenblad M, Jonson T, Mahlamaki EH, et al. Detailed genomic mapping and expression analyses of 12p amplifications in pancreatic carcinomas reveal a 3.5-Mb target region for amplification. Genes Chromosomes Cancer 2002;34:211-223.
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 211-223
    • Heidenblad, M.1    Jonson, T.2    Mahlamaki, E.H.3
  • 12
    • 0033869735 scopus 로고    scopus 로고
    • Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma
    • Yatsuoka T, Sunamura M, Furukawa T, et al. Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma. Am J Gastroenterol 2000;95:2080-2085.
    • (2000) Am J Gastroenterol , vol.95 , pp. 2080-2085
    • Yatsuoka, T.1    Sunamura, M.2    Furukawa, T.3
  • 13
    • 0032427885 scopus 로고    scopus 로고
    • Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer
    • Furukawa T, Yatsuoka T, Youssef EM, et al. Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer. Cytogenet Cell Genet 1998;82:156-159.
    • (1998) Cytogenet Cell Genet , vol.82 , pp. 156-159
    • Furukawa, T.1    Yatsuoka, T.2    Youssef, E.M.3
  • 14
    • 0038243934 scopus 로고    scopus 로고
    • Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer
    • Furukawa T, Sunamura M, Motoi F, et al. Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer. Am J Pathol 2003;162:1807-1815.
    • (2003) Am J Pathol , vol.162 , pp. 1807-1815
    • Furukawa, T.1    Sunamura, M.2    Motoi, F.3
  • 15
    • 0035234009 scopus 로고    scopus 로고
    • Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines
    • Sun C, Yamato T, Furukawa T, et al. Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines. Oncol Rep 2001;8:89-92.
    • (2001) Oncol Rep , vol.8 , pp. 89-92
    • Sun, C.1    Yamato, T.2    Furukawa, T.3
  • 16
    • 0024312156 scopus 로고
    • Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa
    • Koi M, Morita H, Yamada H, et al. Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa. Mol Carcinog 1989;2:12-21.
    • (1989) Mol Carcinog , vol.2 , pp. 12-21
    • Koi, M.1    Morita, H.2    Yamada, H.3
  • 17
    • 0017693945 scopus 로고
    • Stable association of the human transgenome and host murine chromosomes demonstrated with trispecific microcell hybrids
    • Fournier RE, Ruddle FH. Stable association of the human transgenome and host murine chromosomes demonstrated with trispecific microcell hybrids. Proc Natl Acad Sci USA 1977;74:3937-3941.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 3937-3941
    • Fournier, R.E.1    Ruddle, F.H.2
  • 18
    • 15144342086 scopus 로고    scopus 로고
    • Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer
    • Kimura M, Furukawa T, Abe T, et al. Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer. Cancer Res 1998;58:2456-2460.
    • (1998) Cancer Res , vol.58 , pp. 2456-2460
    • Kimura, M.1    Furukawa, T.2    Abe, T.3
  • 19
    • 0034886170 scopus 로고    scopus 로고
    • Human BAC contig covering the deleted region in pancreatic cancer at 12q21
    • Youssef EM, Kaneko K, Yatsuoka T, et al. Human BAC contig covering the deleted region in pancreatic cancer at 12q21. DNA Seq 2001;11:541-546.
    • (2001) DNA Seq , vol.11 , pp. 541-546
    • Youssef, E.M.1    Kaneko, K.2    Yatsuoka, T.3
  • 20
    • 0034667370 scopus 로고    scopus 로고
    • RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype
    • van Golen KL, Wu ZF, Qiao XT, et al. RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype. Cancer Res 2000;60:5832-5838.
    • (2000) Cancer Res , vol.60 , pp. 5832-5838
    • Van Golen, K.L.1    Wu, Z.F.2    Qiao, X.T.3
  • 21
    • 0036259301 scopus 로고    scopus 로고
    • Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines
    • Lefter LP, Furukawa T, Sunamura M, et al. Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines. Genes Chromosomes Cancer 2002;34:234-242.
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 234-242
    • Lefter, L.P.1    Furukawa, T.2    Sunamura, M.3
  • 22
    • 0034652459 scopus 로고    scopus 로고
    • Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12
    • Duda DG, Sunamura M, Lozonschi L, et al. Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12. Cancer Res 2000;60:1111-1116.
    • (2000) Cancer Res , vol.60 , pp. 1111-1116
    • Duda, D.G.1    Sunamura, M.2    Lozonschi, L.3
  • 24
    • 0030892133 scopus 로고    scopus 로고
    • Alternative splicing of hMSH2 in normal human tissues
    • Mori Y, Shiwaku H, Fukushige S, et al. Alternative splicing of hMSH2 in normal human tissues. Hum Genet 1997;99:590-595.
    • (1997) Hum Genet , vol.99 , pp. 590-595
    • Mori, Y.1    Shiwaku, H.2    Fukushige, S.3
  • 25
    • 0017331005 scopus 로고
    • Human pancreatic carcinoma (MIA PaCa-2) in continuous culture: Sensitivity to asparaginase
    • Yunis AA, Arimura GK, Russin DJ. Human pancreatic carcinoma (MIA PaCa-2) in continuous culture: sensitivity to asparaginase. Int J Cancer 1977;19:218-235.
    • (1977) Int J Cancer , vol.19 , pp. 218-235
    • Yunis, A.A.1    Arimura, G.K.2    Russin, D.J.3
  • 26
    • 0025980976 scopus 로고
    • Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18
    • Tanaka K, Oshimura M, Kikuchi R, et al. Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18. Nature 1991;349:340-342.
    • (1991) Nature , vol.349 , pp. 340-342
    • Tanaka, K.1    Oshimura, M.2    Kikuchi, R.3
  • 27
    • 0027171533 scopus 로고
    • Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 1p36 region
    • Tanaka K, Yanoshita R, Konishi M, et al. Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 1p36 region. Oncogene 1993;8:2253-2258.
    • (1993) Oncogene , vol.8 , pp. 2253-2258
    • Tanaka, K.1    Yanoshita, R.2    Konishi, M.3
  • 29
    • 0023234136 scopus 로고
    • Introduction of a normal human chromosome 11 into a Wilms' tumor cell line controls its tumorigenic expression
    • Weissman BE, Saxon PJ, Pasquale SR, et al. Introduction of a normal human chromosome 11 into a Wilms' tumor cell line controls its tumorigenic expression. Science 1987;236:175-180.
    • (1987) Science , vol.236 , pp. 175-180
    • Weissman, B.E.1    Saxon, P.J.2    Pasquale, S.R.3
  • 30
    • 0025176514 scopus 로고
    • Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6
    • Trent JM, Stanbridge EJ, McBride HL, et al. Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6. Science 1990;247:568-571.
    • (1990) Science , vol.247 , pp. 568-571
    • Trent, J.M.1    Stanbridge, E.J.2    McBride, H.L.3
  • 31
    • 17344372572 scopus 로고    scopus 로고
    • Positional cloning of the gene for Nijmegen breakage syndrome
    • Matsuura S, Tauchi H, Nakamura A, et al. Positional cloning of the gene for Nijmegen breakage syndrome. Nat Genet 1998;19:179-181.
    • (1998) Nat Genet , vol.19 , pp. 179-181
    • Matsuura, S.1    Tauchi, H.2    Nakamura, A.3
  • 32
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 33
    • 0034682892 scopus 로고    scopus 로고
    • Genes expressed in human tumor endothelium
    • St Croix B, Rago C, Velculescu V, et al. Genes expressed in human tumor endothelium. Science 2000;289:1197-1202.
    • (2000) Science , vol.289 , pp. 1197-1202
    • St. Croix, B.1    Rago, C.2    Velculescu, V.3
  • 34
    • 0033617532 scopus 로고    scopus 로고
    • Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
    • Bergers G, Javaherian K, Lo KM, et al. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science 1999;284:808-812.
    • (1999) Science , vol.284 , pp. 808-812
    • Bergers, G.1    Javaherian, K.2    Lo, K.M.3
  • 35
    • 1542678174 scopus 로고    scopus 로고
    • A clinically relevant model of human pancreatic adenocarcinoma identifies patterns of metastasis associated with alterations of the TGF-beta/Smad4 signaling pathway
    • Holloway S, Davis M, Jaber R, et al. A clinically relevant model of human pancreatic adenocarcinoma identifies patterns of metastasis associated with alterations of the TGF-beta/Smad4 signaling pathway. Int J Gastrointest Cancer 2003;33:61-69.
    • (2003) Int J Gastrointest Cancer , vol.33 , pp. 61-69
    • Holloway, S.1    Davis, M.2    Jaber, R.3
  • 36
    • 15944388899 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 inhibitor rofecoxib (Vioxx) induces expression of cell cycle arrest genes and slows tumor growth in human pancreatic cancer
    • Tseng WW, Deganutti A, Chen MN, et al. Selective cyclooxygenase-2 inhibitor rofecoxib (Vioxx) induces expression of cell cycle arrest genes and slows tumor growth in human pancreatic cancer. J Gastrointest Surg 2002;6:838-843.
    • (2002) J Gastrointest Surg , vol.6 , pp. 838-843
    • Tseng, W.W.1    Deganutti, A.2    Chen, M.N.3
  • 37
    • 0042284883 scopus 로고    scopus 로고
    • SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions
    • Sato N, Fukushima N, Maehara N, et al. SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions. Oncogene 2003;22:5021-5030.
    • (2003) Oncogene , vol.22 , pp. 5021-5030
    • Sato, N.1    Fukushima, N.2    Maehara, N.3
  • 38
    • 18444403112 scopus 로고    scopus 로고
    • Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: Sea urchin fascin homolog and heat shock protein 47
    • Maitra A, Iacobuzio-Donahue C, Rahman A, et al. Immunohistochemical validation of a novel epithelial and a novel stromal marker of pancreatic ductal adenocarcinoma identified by global expression microarrays: sea urchin fascin homolog and heat shock protein 47. Am J Clin Pathol 2002;118:52-59.
    • (2002) Am J Clin Pathol , vol.118 , pp. 52-59
    • Maitra, A.1    Iacobuzio-Donahue, C.2    Rahman, A.3
  • 39
    • 0037019181 scopus 로고    scopus 로고
    • Expression profiling of microdissected pancreatic adenocarcinomas
    • Crnogorac-Jurcevic T, Efthimiou E, Nielsen T, et al. Expression profiling of microdissected pancreatic adenocarcinomas. Oncogene 2002;21:4587-4594.
    • (2002) Oncogene , vol.21 , pp. 4587-4594
    • Crnogorac-Jurcevic, T.1    Efthimiou, E.2    Nielsen, T.3
  • 40
    • 0037093087 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray
    • Han H, Bearss DJ, Browne LW, et al. Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray. Cancer Res 2002;62:2890-2896.
    • (2002) Cancer Res , vol.62 , pp. 2890-2896
    • Han, H.1    Bearss, D.J.2    Browne, L.W.3
  • 41
    • 0034668176 scopus 로고    scopus 로고
    • Type 2A protein phosphatase, the complex regulator of numerous signaling pathways
    • Zolnierowicz S. Type 2A protein phosphatase, the complex regulator of numerous signaling pathways. Biochem Pharmacol 2000;60:1225-1235.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1225-1235
    • Zolnierowicz, S.1
  • 42
    • 0036318974 scopus 로고    scopus 로고
    • Identification of a chromosome-targeting domain in the human condensation subunit CNAP1/hCAP-D2/Eg7
    • Ball AR, Schmiesing JA, Zhou C, et al. Identification of a chromosome-targeting domain in the human condensation subunit CNAP1/hCAP-D2/Eg7. Mol Cell Biol 2002;22:5769-5781.
    • (2002) Mol Cell Biol , vol.22 , pp. 5769-5781
    • Ball, A.R.1    Schmiesing, J.A.2    Zhou, C.3
  • 43
    • 0036911117 scopus 로고    scopus 로고
    • A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein
    • Tang Q, Staub CM, Gao G, et al. A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein. Mol Biol Cell 2002;13:4484-4496.
    • (2002) Mol Biol Cell , vol.13 , pp. 4484-4496
    • Tang, Q.1    Staub, C.M.2    Gao, G.3
  • 44
    • 0037112439 scopus 로고    scopus 로고
    • Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas
    • Oka T, Ouchida M, Koyama M, et al. Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas. Cancer Res 2002;62:6390-6394.
    • (2002) Cancer Res , vol.62 , pp. 6390-6394
    • Oka, T.1    Ouchida, M.2    Koyama, M.3
  • 45
    • 0034129271 scopus 로고    scopus 로고
    • Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells
    • Opdam FJ, Kamps G, Croes H, et al. Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells. Eur J Cell Biol 2000;79:308-316.
    • (2000) Eur J Cell Biol , vol.79 , pp. 308-316
    • Opdam, F.J.1    Kamps, G.2    Croes, H.3


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