Identification of a novel metastasis-suppressor region on human chromosome 12

Cancer Research

Volumn 58, Issue 16, 1998, Pages 3561-3565

  Luu, Hue H ^a   Zagaja, Gregory P ^a   Dubauskas, Zita ^a   Chen, Stephen L ^a   Smith, Robert C ^a   Watabe, Kounosuke ^b   Ichikawa, Yayoi ^c   Ichikawa, Tomohiko ^c   Davis, Elizabeth M ^a   Le Beau, Michelle M ^a   Rinker Schaeffer, Carrie W ^a,d  

^a UNIVERSITY OF CHICAGO   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Section of Urology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CHROMOSOME 12; CONTROLLED STUDY; HUMAN; LUNG METASTASIS; MALE; METASTASIS POTENTIAL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE CARCINOMA; RAT; SEQUENCE TAGGED SITE; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CHROMOSOMES, HUMAN, PAIR 12; DRUG RESISTANCE, NEOPLASM; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LUNG NEOPLASMS; MALE; MICE; MICE, SCID; NEOMYCIN; NEOPLASM METASTASIS; PROSTATIC NEOPLASMS; RATS; TUMOR CELLS, CULTURED;

EID: 0032529268     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Carter, H. B., and Coffey, D. S. The prostate: an increasing medical problem. Prostate, 16: 39-48, 1990.
2. Isaacs, J. T. Molecular markers for prostate cancer metastasis. Developing diagnostic methods for predicting the aggressiveness of prostate cancer. Am. J. Pathol., 150: 1511-1521, 1997.
3. Scardino, P. T., Weaver, R., and Hudson, M. A. Early detection of prostate cancer. Hum. Pathol., 23: 211-222, 1992.
4. Rinker-Schaeffer, C. W., Partin, A. W., Isaacs, W. B., Coffey, D. S., and Isaacs, J. T. Molecular and cellular changes associated with the acquisition of metastatic ability by prostatic cancer cells. Prostate, 25: 249-265, 1994.
5. Nihei, N., Ichikawa, T., Kawana, Y., Kuramochi, H., Kugo, H., Oshimura, M., Hayata, I., Shimazaki, J., and Ito, H. Mapping of metastasis suppressor gene(s) for rat prostate cancer on the short arm of human chromosome 8 by irradiated microcell-mediated chromosome transfer. Genes Chromosomes Cancer, 17: 260-268, 1996.
6. Nihei, N., Ichikawa, T., Kawana, Y., Kuramochi, H., Kugo, H., Oshimura, M., Killary, A. M., Rinker-Schaeffer, C. W., Barrett, J. C., Isaacs, J. T., and Shimazaki, J. Localization of metastasis suppressor gene(s) for rat prostatic cancer to the long arm of human chromosome 10. Genes Chromosomes Cancer, 14: 112-119, 1995.
7. Dong, J. T., Lamb, P. W., Rinker-Schaeffer, C. W., Vukanovic, J., Ichikawa, T., Isaacs, J. T., and Barrett, J. C. KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science (Washington DC), 268: 884-886, 1995.
8. Chekmareva, M. A., Hollowell, C. M., Smith, R. C., Davis, E. M., LeBeau, M. M., and Rinker-Schaeffer, C. W. Localization of prostate cancer metastasis-suppressor activity on human chromosome 17. Prostate, 33: 271-280, 1997.
9. Gao, A. C., Lou, W., Dong, J. T., and Isaacs, J. T. CD44 is a metastasis suppressor gene for prostate cancer located on human chromosome 11p13. Cancer Res., 57: 846-849, 1997.
10. Dong, J. T., Suzuki, H., Pin, S. S., Bova, G. S., Schalken, J. A., Isaacs, W. B., Barrett, J. C., and Isaacs, J. T. Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss. Cancer Res., 56: 4387-4390, 1996.
11. Adachi, M., Taki, T., Ieki, Y., Huang, C. L., Higashiyama, M., and Miayke, M. Correlation of KAI1/CD/82 gene expression with good prognosis in patients with non-small cell lung cancer. Cancer Res., 56: 1751-1755, 1996.
12. Guo, X., Friess, H., Graber, H. U., Kashiwagi, M., Zimmermann, A., Korc, M., and Buchler, M. W. KAI1 expression is up-regulated in early pancreatic cancer and decreased in the presence of metastases. Cancer Res., 56: 4876-4880, 1996.
13. Van de Van, W., Hagemeijer, A., Kucherlapati, R., and Maynen P. Report of the international meeting on chromosome 12 genes in cancer. Cytogenet. Cell Genet., 73: 25-32, 1996.
14. Brothman, A. R., Watson, M. J., Zhu, X. L., Williams, B. J., and Rohr, L. R. Evaluation of 20 archival prostate tumor specimens by fluorescence in situ hybridization (FISH). Cancer Genet. Cytogenet., 75: 40-44, 1994.
15. Murty, V. V., Renault, B., Bosl, G. J., Kucherlapati, R., and Chaganti, R. S. Physical mapping of a commonly deleted region, the site of a candidate tumor suppressor gene, at 12q22 in human male germ cell tumor. Genomics, 35: 562-570, 1996.
16. Hatta, Y., Takeuchi, S., Yokota, J., and Koeffler, H. P. Ovarian cancer has frequent loss of heterozygosity at chromosome 12p12.3-13.1 (region of TEL and Kip1 loci) and chromosome 12q23-ter: evidence for two new tumour-suppressor genes. Br. J. Cancer, 75: 1256-1262, 1997.
17. Schmutte, C., Baffa, R., Veronese, L. M., Murakumo, Y., and Fishel, R. Human thymine-DNA glycosylase maps at chromosome 12q22-q24.1: a region of high loss of heterozygosity in gastric cancer. Cancer Res., 57: 3010-3015, 1997.
18. Berube, N. G., Speevak, M. D., and Chevrette, M. Suppression of tumorigenicity of human prostate cancer cells by introduction of human chromosome (de112)(q13). Cancer Res., 54: 3077-3081, 1994.
19. Ichikawa, T., Ichikawa, Y., Dong, J., Hawkins, A. L., Griffin, C. A., Isaacs, W. B., Oshimura, M., Barrett, J. C., and Isaacs, J. T. Localization of metastasis suppressor gene(s) for prostatic cancer to the short arm of human chromosome 11. Cancer Res., 52: 3486-3490, 1992.
20. Ichikawa, T., Kyprianou, N., and Isaacs, J. T. Genetic instability and the acquisition of metastatic ability by rat mammary cancer cells following v-H-ras oncogene transfection. Cancer Res., 50: 6349-6357, 1990.