Vitamin K supplementation does not significantly impact bone mineral density and biochemical markers of bone in pre- and perimenopausal women

Nutrition Research

Volumn 28, Issue 9, 2008, Pages 577-582

  Volpe, Stella L ^a   Leung, May May ^b   Giordano, Heather ^c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b IL   (United States)

^c Department of Exercise Physiology ^*  (United States)

Author keywords

Bone mineral density; Osteocalcin; Phylloquinone; Urinary N telopeptide; Vitamin K; Women

Indexed keywords

AMINO TERMINAL TELOPEPTIDE; BIOCHEMICAL MARKER; OSTEOCALCIN; PHYTOMENADIONE; PLACEBO;

ADULT; ARTICLE; BODY FAT; BODY WEIGHT; BONE DENSITY; BONE METABOLISM; CLIMACTERIUM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIETARY INTAKE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; PREMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VITAMIN SUPPLEMENTATION;

ABSORPTIOMETRY, PHOTON; ADULT; BIOLOGICAL MARKERS; BODY FAT DISTRIBUTION; BONE AND BONES; BONE DENSITY; COLLAGEN TYPE I; DIET; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MIDDLE AGED; OSTEOCALCIN; PEPTIDES; PERIMENOPAUSE; PLACEBOS; VITAMIN K; VITAMIN K 1;

EID: 49349103319     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nutres.2008.06.006     Document Type: Article

References (26)

1. Shearer M. Vitamin K. Lancet North Am Ed 345 (1995) 229-235
2. Booth S., Tucker K., Chen H., Hannan M., Gagnon D., Cupples L., et al. Dietary vitamin K intakes are associated with hip fractures but not with bone mineral density in elderly men and women. Am J Clin Nutr 71 (2000) 1201-1208
3. Booth S., Broe K., Gagnon D., Tucker K., Hannan M., McLean R., et al. Vitamin K intake and bone mineral density in women and men. Am J Clin Nutr 77 (2003) 512-516
4. Feskanich D., Weber P., Willet W., Rockett H., Booth S., and Colditz G. Vitamin K intake and hip fractures in women: a prospective study. Am J Clin Nutr 69 (1999) 74-79
5. 1 supplementation retards bone loss in postmenopausal women between 50 and 60 years of age. Calcif Tissue Int 73 (2003) 21-26
6. Binkley N., Krueger D., Engelke J., Foley A., and Suttie J. Vitamin K supplementation reduces serum concentrations of undercarboxylated osteocalcin in healthy young and elderly adults. Am J Clin Nutr 72 (2000) 1523-1528
7. Garber A., Binkley N., Krueger D., and Suttie J. Comparison of phylloquinone availability from food sources or as a supplement in human subjects. J Nutr 129 (1999) 1201-1203
8. Lunar D.P.X. Version Prodigy 10149 (1999), Lunar Corporation, Madison (Wis) [Computer Software]
9. Boonen S., Cheng X., Nicholson P.H., Verbeke G., Broos P., and Dequeker J. The accuracy of peripheral skeletal assessment at the radius in estimating femoral bone density as measured by dual-energy X-ray absorptiometry: a comparative study of single-photon absorptiometry and computed tomography. J Intern Med. 242 4 (1997) 323-328
10. Mole P.A., McMurdo M.E., and Paterson C.R. Evaluation of peripheral dual energy X-ray absorptiometry: comparison with single photon absorptiometry of the forearm and dual energy X-ray absorptiometry of the spine or femur. Br J Radiol. 71 844 (1998) 427-432
11. White J., Harris S.S., Dallal G.E., and Dawson-Huges B. Precision of single versus bilateral hip bone mineral density scans. J Bone Mineral Res. 18 Suppl. 2 (2003) S314
12. Kaptoge S., Jakes R., Dalzell N., Wareham N., Khaw K., Loveridge N., et al. Effects of physical activity on evolution of proximal femur structure in a younger elderly population. Bone. 40 2 (2007) 506-515
13. Block G. Health habits and history questionnaire (1987), National Cancer Institute, Bethesda (Md)
14. Dietsys, Full'87 (1987), National Cancer Institute, Bethesda (Md) [Computer Software]
15. SPSS, 12.0 (2003), SPSS, Chicago (Ill) [Computer Software]
16. 2enhances osteocalcin accumulation in the extracellular matrix of human osteoblasts in vitro. J Bone Miner Res 12 (1997) 431-438
17. Koshihara Y., Hoshi K., Okawara R., Ishibashi H., and Yamamoto S. Vitamin K stimulates osteoblastogenesis and inhibits osteoclastogenesis in human bone marrow cell culture. J Endocrinol 176 (2003) 339-348
18. Tucker K. Dietary intake and bone status with aging. Curr Pharm Des 9 (2003) 2687-2704
19. Dawson-Hughes B., and Harris S. Regional changes in body composition by time of year in healthy postmenopausal women. Am J Clin Nutr 56 (1992) 307-313
20. Plasqui G., and Westerterp K. Seasonal variation in total energy expenditure and physical activity in Dutch young adults. Obes Res 12 (2003) 688-694
21. Bergstralh E., Sinaki M., Offord K., Wahner H., and Melton J. Effect of season on physical activity score, back extensor muscle strength, and lumbar bone mineral density. J Bone Miner Res 5 (1990) 371-377
22. Institute of Medicine. Dietary reference intakes for calcium, phosphorous, magnesium, vitamin D, and fluoride (1999), National Academy Press, Washington (DC)
23. Institute of Medicine. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc (2001), National Academy Press, Washington (DC)
24. Chapman K., Chan M., and Clark C. Factors influencing dairy calcium intake in women. J Am Coll Nutr 14 (1995) 336-340
25. US Department of Health and Human Services. National health and nutrition examination survey: 1999-2000 (2000) [Hyattsville, MD]
26. Bolton-Smith C., McMurdo M.E., Paterson C.R., Mole P.A., Harvey J.M., Fenton S.T., Prynne C.J., Mishra G.D., and Shearer M.J. Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women. J Bone Miner Res. 22 4 (2007) 509-519