Effects of physical activity on evolution of proximal femur structure in a younger elderly population

Bone

Volumn 40, Issue 2, 2007, Pages 506-515

  Kaptoge, S ^a,b   Jakes, R W ^b   Dalzell, N ^a,b   Wareham, N ^b   Khaw, K T ^b   Loveridge, N ^b   Beck, T J ^c   Reeve, J ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Centre of mass; Fracture resistance; Hip geometry; Hip structural analysis; Osteoporosis; Physical activity

Indexed keywords

ADULT; AGE; AGED; AGING; ANALYTIC METHOD; ARTICLE; BODY HEIGHT; BODY WEIGHT; BONE STRUCTURE; BONE TISSUE; CORTICAL BONE; CYCLING; DAILY LIFE ACTIVITY; DATA ANALYSIS SOFTWARE; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR NECK; FOLLOW UP; FORCED EXPIRATION; HIP FRACTURE; HIP STRUCTURAL ANALYSIS; HUMAN; LIFESPAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; QUESTIONNAIRE; STATISTICAL MODEL; TIME; UNITED KINGDOM; WEIGHT BEARING; YOUNG MODULUS;

AGED; AGING; BODY WEIGHT; EXERCISE; FEMALE; FEMUR; FEMUR NECK; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES;

EID: 33845998528     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.09.021     Document Type: Article

References (40)

1. In: Murray J.F. (Ed). Primer on the metabolic bone diseases and disorders of mineral metabolism. 5th ed. (2003), American Society for Bone and Mineral Research, 2025 M Street, NW Suite 800, Washington, DC 20036-3309, USA
2. Coupland C.A.C., Cliffe S.J., Bassey E.J., Grainge M.J., Hosking D.J., and Chilvers C.E.D. Habitual physical activity and bone mineral density in postmenopausal women in England. Int. J. Epidemiol. 28 (1999) 241-246
3. Farahmand B.Y., Persson P.G., Michaelsson K., Baron J.A., Alberts A., Moradi T., et al. Physical activity and hip fracture: a population-based case-control study. Int. J. Epidemiol. 29 (2000) 308-314
4. Kaptoge S.K., Dalzell N., Jakes R.W., Wareham N., Day N.E., Khaw K.T., et al. Hip section modulus, a measure of bending resistance, is more strongly related to reported physical activity than BMD. Osteoporos. Int. 14 (2003) 941-949
5. Beck T.J., Oreskovic T.L., Stone K.L., Ruff C.B., Ensrud K., Nevitt M.C., et al. Structural adaptation to changing skeletal load in the progression toward hip fragility: the study of osteoporotic fractures. J. Bone Miner. Res. 16 (2001) 1108-1119
6. McCreadie B.R., and Goldstein S.A. Biomechanics of fracture: is bone mineral density sufficient to assess risk?. J. Bone Miner. Res. 15 (2000) 2305-2308
7. Seeman E. From density to structure: growing up and growing old on the surfaces of bone. J. Bone Miner. Res. 12 (1997) 509-521
8. Duan Y.B., Beck T.J., Wang X.F., and Seeman E. Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J. Bone Miner. Res. 18 (2003) 1766-1774
9. Karlsson K.M., Sernbo I., Obrant K.J., RedlundJohnell I., and Johnell O. Femoral neck geometry and radiographic signs of osteoporosis as predictors of hip fracture. Bone 18 (1996) 327-330
10. Bell K.L., Loveridge N., Power J., Garrahan N., Stanton M., Lunt M., et al. Structure of the femoral neck in hip fracture: cortical bone loss in the inferoanterior to superoposterior axis. J. Bone Miner. Res. 14 (1999) 111-119
11. Bell K., Loveridge N., Power J., Garrahan N., Meggitt B., and Reeve J. Regional differences in cortical porosity in the fractured femoral neck. Bone 24 (1999) 57-64
12. Crabtree N., Loveridge N., Parker M., Rushton N., Power J., Bell K.L., et al. Intracapsular hip fracture and the region-specific loss of cortical bone: analysis by peripheral quantitative computed tomography. J. Bone Miner. Res. 16 (2001) 1318-1328
13. Mayhew P.M., Thomas C.D., Clement J.G., Loveridge N., Beck T.J., Bonfield W., et al. Relation between age, femoral neck cortical stability, and hip fracture risk. Lancet 366 (2005) 129-135
14. Yoshikawa T., Turner C.H., Peacock M., Slemenda C.W., Weaver C.M., Teegarden D., et al. Geometric structure of the femoral neck measured using dual-energy X-ray absorptiometry. J. Bone Miner. Res. 9 (1994) 1053-1064
15. Beck T.J., Looker A.C., Ruff C.B., Sievanen H., and Wahner H.W. Structural trends in the ageing femoral neck and proximal shaft: analysis of the third national health and nutrition examination survey dual-energy X-ray absorptiometry data. J. Bone Miner. Res. 15 (2000) 2297-2304
16. Lanyon L., and Skerry T. Postmenopausal osteoporosis as a failure of bone's adaptation to functional loading: a hypothesis. J. Bone Miner. Res. 16 (2001) 1937-1947
17. Lovejoy C.O. Evolution of human walking. Sci. Am. 259 (1988) 118-125
18. Lovejoy C.O., Meindl R.S., Ohman J.C., Heiple K.G., and White T.D. The maka femur and its bearing on the antiquity of human walking: applying contemporary concepts of morphogenesis to the human fossil record. Am. J. Phys. Anthropol. 119 (2002) 97-133
19. Ohman J.C., Krochta T.J., Lovejoy C.O., Mensforth R.P., and Latimer B. Cortical bone distribution in the femoral neck of hominoids: implications for the locomotion of Australopithecus afarensis. Am. J. Phys. Anthropol. 104 (1997) 117-131
20. Singh M., Nagrath A.R., and Maini P.S. Changes in trabecular pattern of the upper end of the femur as an index of osteoporosis. J. Bone Joint Surg. Am. 52 (1970) 457-467
21. Crabtree N., Lunt M., Holt G., Kröger H., Burger H., Grazio S., et al. Hip geometry, bone mineral distribution and bone strength in European men and women: the EPOS study. Bone 27 (2000) 151-160
22. Day N., Oakes S., Luben R., Khaw K.-.T., Bingham S., Welch A., et al. EPIC in Norfolk: study design and characteristics of the cohort. Br. J. Cancer 80 (1999) 95-103
23. Beck T.J., Ruff C.B., Warren K.E., Scott W.W., and Gopala U. Predicting femoral neck strength from bone mineral data: a structural approach. Invest. Radiol. 25 (1990) 6-18
24. Mourtada F., Beck T., Hauser D., Ruff C., and Bao G. Curved beam model of the proximal femur for estimating stress using dual x-ray absorptiometry derived structural geometry. J. Orthop. Res. 14 (1996) 483-492
25. Jakes R., Khaw K.-.T., Day N., Bingham S., Welch A., Oakes S., et al. Patterns of physical activity and ultrasound attenuation by heel bone among Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): population based study. BMJ 322 (2001) 140-143
26. Wareham N.J., Jakes R.W., Rennie K.L., Mitchell J., Hennings S., and Day N.E. Validity and repeatability of the EPIC-Norfolk physical activity questionnaire. Int. J. Epidemiol. 31 (2002) 168-174
27. Matthis C., Weber U., O'Neill T.W., and Raspe H. The European Vertebral Osteoporosis Study Group. Health impact associated with vertebral deformities: results from the European Vertebral Osteoporosis Study. Osteoporos. Int. 8 (1998) 364-372
28. Pelkonen M., Notkola I.L., Lakka T., Tukiainen H.O., Kivinen P., and Nissinen A. Delaying decline in pulmonary function with physical activity-A 25-year follow-up. Am. J. Respir. Crit. Care Med. 168 (2003) 494-499
29. Lunt M., Masaryk P., Scheidt-Nave C., Nijs J., Poor G., Pols H., et al. The effects of lifestyle, dietary dairy intake and diabetes on bone density and vertebral deformity prevalence: the EVOS study. Osteoporos. Int. 12 (2001) 688-698
30. O'Neill T.W., Cooper C., Cannata J.B., Diaz Lopez J.B., Hoszowski K., Johnell O., et al. Reproducibility of a questionnaire on risk factors for osteoporosis in a multicentre prevalence survey: the European Vertebral Osteoporosis study. Int. J. Epidemiol. 23 (1994) 559-565
31. Kaptoge S.K., Dalzell N., Loveridge N., Beck T.J., Khaw K.-.T., and Reeve J. Effects of gender, anthropometric variables and aging on the evolution of hip strength in men and women aged over 65. Bone 32 (2003) 561-570
32. Power J., Loveridge N., Lyon A., Rushton N., Parker M., and Reeve J. Osteoclastic cortical erosion as a determinant of subperiosteal osteoblastic bone formation in the femoral neck s response to BMU imbalance. Effects of stance-related loading and hip fracture. Osteoporos. Int. 16 (2005) 1049-1056
33. George W.T., and Vashishth D. Susceptibility of aging human bone to mixed-mode fracture increases bone fragility. Bone 38 (2006) 105-111
34. Bell G.H., Dunbar O., Beck J.S., and Gibb A. Variations in strength of vertebrae with age and their relation to osteoporosis. Calcif. Tissue Res. 1 (1967) 75-86
35. Heaney R.P., Barger-Lux M.J., Davies K.M., Johnson R.R., and Gong M.L. Bone dimensional change with age: interactions of genetic, hormonal, and body size variables. Osteoporos. Int. 7 (1997) 426-431
36. Smith R.W., and Walker R.R. Femoral expansion in ageing women: implications for osteoporosis and fractures. Science 145 (1964) 156-157
37. Parfitt A.M. Richmond Smith as a clinical investigator: his work on periosteal bone expansion and nutritional and endocrine aspects of osteoporosis in light of current concepts. Henry Ford Hosp. Med. J. 28 (1980) 95-107
38. Mosley J.R., and Lanyon L.E. Strain rate as a controlling influence on adaptive modeling in response to dynamic loading of the ulna in growing male rats. Bone 23 (1998) 313-318
39. Noble B.S., Peet N., Stevens H.Y., Brabbs A., Mosley J.R., Reilly G.C., et al. Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone. Am. J. Physiol., Cell Physiol. 284 (2003) C934-C943
40. Raisz L.G., and Seeman E. Causes of age-related bone loss and bone fragility: an alternative view. J. Bone Miner. Res. 11 (2001) 1948-1952