CRH mRNA expression in the hypothalamic paraventricular nucleus is inhibited despite the activation of the hypothalamo-pituitary-adrenal axis during starvation

Brain Research

Volumn 1228, Issue , 2008, Pages 107-112

  Nishiyama, Mitsuru ^a   Makino, Shinya ^a   Iwasaki, Yasumasa ^a   Tanaka, Yasushi ^a   Nazarloo, Hossein Pournajafi ^a   Kaneda, Tadafumi ^a   Asaba, Koichi ^a   Hashimoto, Kozo ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Corticosterone; Corticosterone releasing hormone; In situ hybridization; Paraventricular nucleus; Starvation

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; GLUCOCORTICOID; MESSENGER RNA;

ADRENAL CORTEX FUNCTION; ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATERING SERVICE; CONTROLLED STUDY; HYPERADRENOCORTICISM; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHAM PROCEDURE; STARVATION; THALAMUS MIDLINE NUCLEUS;

ADRENALECTOMY; ADRENOCORTICOTROPIC HORMONE; ANIMALS; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; GENE EXPRESSION; GLUCOSE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; HYPOTHALAMUS; IMMUNORADIOMETRIC ASSAY; IN SITU HYBRIDIZATION; INJECTIONS, SUBCUTANEOUS; INSULIN; MALE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PITUITARY-ADRENAL SYSTEM; RATS; RATS, WISTAR; RNA, MESSENGER; STARVATION;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 49349100933     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.06.065     Document Type: Article

References (33)

1. Ahima R.S., Prabarakan D., Mantzoros C., Qu D., Lowell B., Maratos-Flier E., and Flier J.S. Role of leptin in the neuroendocrine response to fasting. Nature 382 (1996) 250-252
2. Arase K., York D.A., Shimizu H., Shargil N.S., and Bray G.A. Effect of corticotropin-releasing factor on food intake and brown adipose tissue thermogenesis in rats. Am. J. Physiol. 255 (1988) E255-E259
3. Bale T.L., and Vale W.W. CRF and CRF receptors: role in stress responsivity and other behaviors. Annu. Rev. Pharmacol. Toxicol. 44 (2004) 525-557
4. Beyer H.S., Matta S.G., and Sharp B.M. Regulation of the messenger ribonucleic acid for corticotropin-releasing factor in the paraventricular nucleus and other brain sites of the rat. Endocrinology 123 (1988) 2117-2123
5. Brady L.S., Smith M.A., Gold P.W., and Herkenham M. Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats. Neuroendocrinology 52 (1990) 441-447
6. Cascio C.S., Shinsako J., and Dallman M.F. The suprachiasmatic nuclei stimulate evening ACTH secretion in the rat. Brain Res. 423 (1987) 173-178
7. Charmandari E., Tsigos C., and Chrousos G. Endocrinology of the stress response. Annu. Rev. Physiol. 67 (2005) 259-284
8. Dallman M.F., Akana S.F., Bhatnagar S., Bell M.E., Choi S., Chu A., Horsley C., Levin N., Meijer O., Soriano L.R., Strack A.M., and Viau V. Starvation: early signals, sensors, and sequelae. Endocrinology 140 (1999) 4015-4023
9. Dallman M.F., Strack A.M., Akana S.F., Bradbury M.J., Hanson E.F., Scribner K.A., and Smith M. Feast and famine: critical role of glucocorticoids with insulin in daily energy flow. Front Neuroendocrinol. 14 (1993) 303-347
10. Edwards A.V., and Jones C.T. The effect of splanchnic nerve stimulation on adrenocortical activity in conscious calves. J. Physiol. 382 (1987) 385-396
11. Flier J.S. Obesity wars: molecular progress confronts an expanding epidemic. Cell 116 (2004) 337-350
12. Glowa J., and Gold P.W. Corticotropin-releasing hormone produces profound anorexigenic effects in the rhesus monkey. Neuropeptides 18 (1991) 55-61
13. Han E.S., Evans T.R., and Nelson J.F. Adrenocortical responsiveness to adrenocorticotropic hormone is enhanced in chronically food-restricted rats. J. Nutr. 128 (1998) 1415-1420
14. Heinriches S.C., and Richard D. The role of corticotropin-releasing factor and urocortin in the modulation of ingestive behavior. Neuropeptides 33 (1999) 350-359
15. Herman J.P. In situ hybridization analysis of vasopressin gene transcription in the paraventricular and supraoptic nuclei of the rat: regulation by stress and glucocorticoid. J. Comp. Neurol. 363 (1995) 15-27
16. Huang Q., Rivest R., and Richard D. Effects of leptin on corticotropin-releasing factor (CRF) synthesis and CRF neuron activation in the paraventricular hypothalamic nucleus of obese (ob/ob) mice. Endocrinology 139 (1998) 1524-1532
17. Hwang B.H., and Guntz J.M. Downregulation of corticotropin-releasing factor mRNA, but not vasopressin mRNA, in the paraventricular hypothalamic nucleus of rats following nutritional stress. Brain Res. Bull. 43 (1997) 509-514
18. Jingami H., Matsukura S., Numa S., and Imura H. Effect of adrenalectomy and dexamethasone administration on the level of prepro-corticotropin-releasing factor messenger ribonucleic acid (mRNA) in the hypothalamus and adrenocorticotropin/beta-lipotropin precursor mRNA in the pituitary in rats. Endocrinology 117 (1985) 1314-1320
19. Jingami H., Mizuno N., Takahashi H., Shibahara S., Furutani Y., Imura H., and Numa S. Cloning and sequence analysis of cDNA for rat corticotropin-releasing factor precursor. FEBS Lett. 191 (1985) 63-66
20. Krahn D.D., and Gosnell B.A. Behavioral effects of corticotropin-releasing factor: localization and characterization of central effects. Brain Res. 443 (1988) 63-69
21. Lebrethon M.C., Naville D., Begeot M., and Saez J.M. Regulation of corticotropin receptor number and messenger RNA in cultured human adrenocortical cells by corticotropin and angiotensin II. J. Clin. Invest. 93 (1994) 1828-1833
22. Liu J., Clarke I., Funder J., and Engler D. Studies of the secretion of corticotropin-releasing factor and arginine vasopressin into the hypophysial-portal circulation of the conscious sheep. J. Clin. Invest. 93 (1994) 1439-1450
23. Makino S., Gold P.W., and Schulkin J. Corticosterone effects on corticotropin-releasing hormone mRNA in the central nucleus of the amygdala and the parvocellular region of the paraventricular nucleus of the hypothalamus. Brain Res. 640 (1994) 105-112
24. Makino S., Hashimoto K., and Gold P.W. Multiple feedback mechanisms activating corticotropin-releasing hormone system in the brain during stress. Pharmacol. Biochem. Behav. 73 (2002) 147-158
25. Mizuno T.M., and Mobbs C.V. Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting. Endocrinology 140 (1999) 814-817
26. Muglia L., Jacobson L., Dikkes P., and Majzoub J.A. Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature 373 (1995) 427-432
27. Nishiyama M., Makino S., Asaba K., and Hashimoto K. Leptin effects on the expression of type-2 CRH receptor mRNA in the ventromedial hypothalamus in the rat. J. Neuroendocrinol. 11 (1999) 307-314
28. Qu D., Ludwig D.S., Gammeltoft S., Piper M., Pelleymounter M.A., Cullen M.J., Mathes W.F., Pizypek R., Kanarek R., and Maratos-Flier E. A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature 380 (1996) 243-247
29. Richard D. Involvement of corticotropin-releasing factor in the control of food intake and energy expenditure. Ann. NY Acad. Sci. 697 (1993) 155-172
30. Schwartz M.W., Dallman M.F., and Woods S.C. Hypothalamic response to starvation: implications for the study of wasting disorders. Am. J. Physiol. 269 (1995) R949-R957
31. Suemaru S., Hashimoto K., Hattori T., Inoue H., Kageyama J., and Ota Z. Starvation-induced changes in rat brain corticotropin-releasing factor (CRF) and pituitary-adrenocortical response. Life Sci. 39 (1986) 1161-1166
32. Venihaki M., and Majzoub J.A. Lessons from CRH knockout mice. Neuropeptides 36 (2002) 96-102
33. Watts A.G., Tanimura S., and Sanchez-watts G. Corticotropin-releasing hormone and arginine vasopressin gene transcription in the hypothalamic paraventricular nucleus of unstressed rats: daily rhythms and their interactions with corticosterone. Endocrinology 145 (2004) 529-540