Aortic Stenosis: It Is a Hot Topic. The Link to Coronary Artery Disease**Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.

Journal of the American College of Cardiology

Volumn 52, Issue 9, 2008, Pages 764-766

  Carabello, Blase A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

aortic stenosis; inflammation; valvular heart disease

Indexed keywords

LOW DENSITY LIPOPROTEIN;

ANGIOCARDIOGRAPHY; AORTA STENOSIS; ATHEROSCLEROTIC PLAQUE; CALCIFICATION; CARDIOVASCULAR RISK; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY CIRCUMFLEX BRANCH; CORONARY ARTERY DISEASE; DISEASE COURSE; EDITORIAL; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE OUTFLOW TRACT OBSTRUCTION; HUMAN; INTERNAL MAMMARY ARTERY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RIGHT CORONARY ARTERY;

AORTIC VALVE STENOSIS; CORONARY ARTERY DISEASE; HUMANS;

EID: 49349094056     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2008.05.035     Document Type: Editorial

References (30)

1. Otto C.M., Kuusisto J., Reichenback D.D., Gown A.M., and O'Brien K.D. Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies. Circulation 90 (1994) 844-853
2. Otto C.M., Lind B.K., Kitzman D.W., et al. Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med 341 (1999) 142-147
3. Chandra H.R., Goldstein J.A., Choudhary N., et al. Adverse outcome in aortic sclerosis is associated with coronary artery disease and inflammation. J Am Coll Cardiol 43 (2004) 169-175
4. Stewart B.F., Siscovick D., Lind B.K., et al. Clinical factors associated with calcific aortic valve disease: Cardiovascular Health Study. J Am Coll Cardiol 29 (1997) 630-634
5. Chui M.C., Newby D.E., Panarelli M., Bloomfield P., and Boon N.A. Association between calcific aortic stenosis and hypercholesterolemia: is there a need for a randomized controlled trial of cholesterol-lowering therapy?. Clin Cardiol 24 (2001) 52-55
6. Aronow W.S., Ahn C., Kronzon I., and Goldman M.E. Association of coronary risk factors and use of statins with progression of mild vavlular aortic stenosis in older persons. Am J Cardiol 88 (2001) 693-695
7. Peltier M., Trojette F., Sarano M.E., Grigioni F., Slama M.A., and Tribouilloy C.M. Relation between cardiovascular risk factors and nonrheumatic severe calcific aortic stenosis among patients with a three-cuspid aortic valve. Am J Cardiol 91 (2003) 97-99
8. Pohle K., Maffert R., Ropers D., et al. Progression of aortic valve calcification: association with coronary atherosclerosis and cardiovascular risk factors. Circulation 104 (2001) 1927-1932
9. Drolet M.C., Arsenault M., and Couet J. Experimental aortic valve stenosis in rabbits. J Am Coll Cardiol 41 (2003) 1211-1217
10. Weiss R.M., Ohashi M., Miller J.D., Young S.G., and Heistad D.D. Calcific aortic valve stenosis in old hypercholesterolemic mice. Circulation 114 (2006) 2065-2069
11. Cowell S.J., Newby D.E., Prescott R.J., et al. A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis. N Engl J Med 352 (2005) 2389-2397
12. Novaro G.M., Tiong I.Y., Pearce G.L., Lauer M.S., Sprecher D.L., and Griffin B.P. Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis. Circulation 104 (2001) 2205-2209
13. Shavelle D.M., Takasu J., Budoff M.J., Mao S., Zhao X.Q., and O'Brien K.D. HMG CoA reductase inhibitor (statin) and aortic valve calcium. Lancet 359 (2002) 1125-1126
14. Bellamy M.F., Pellikka P.A., Klarich K.W., Tajik A.J., and Enriquez-Sarano M. Association of cholesterol levels, hydroxymethylglutaryl coenzyme-A reductase inhibitor treatment, and progression of aortic stenosis in the community. J Am Coll Cardiol 40 (2002) 1723-1730
15. Moura L.M., Ramos S.F., Zamorano J.L., et al. Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis. J Am Coll Cardiol 49 (2007) 554-561
16. Tolstrup K., Roldan C.A., Qualls C.R., and Crawford M.H. Aortic valve sclerosis, mitral annular calcium, and aortic root sclerosis as markers of atherosclerosis in men. Am J Cardiol 89 (2002) 1030-1034
17. Ridker P.M., Wilson P.W., and Grundy S.M. Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?. Circulation 109 (2004) 2818-2825
18. Stefanadis C., Diamantopoulos L., Vlachopoulos C., et al. Thermal heterogeneity within human atherosclerotic coronary arteries detected in vivo: a new method of detection by application of a special thermography catheter. Circulation 99 (1999) 1965-1971
19. Casscells W., Hathorn B., David M., et al. Thermal detection of cellular infiltrates in living atherosclerotic plaques: possible implications for plaque rupture and thrombosis. Lancet 347 (1996) 1447-1451
20. Toutouzas K., Drakopoulou M., Synetos A., et al. In vivo aortic valve thermal heterogeneity in patients with nonrheumatic aortic valve stenosis: the first in vivo experience in humans. J Am Coll Cardiol 52 (2008) 758-763
21. Goldbarg S.H., Elmariah S., Miller M.A., and Fuster V. Insights into degenerative aortic valve disease. J Am Coll Cardiol 50 (2007) 1205-1213
22. Garg V., Muth A.N., Ransom J.F., et al. Mutations in NOTCH1 cause aortic valve disease. Nature 437 (2005) 270-274
23. Grande K.J., Cochran R.P., Reinhall P.G., and Kunzelman K.S. Stress variations in the human aortic root and valve: the role of anatomic asymmetry. Ann Biomed Eng 26 (1998) 534-545
24. Choo S.J., McRae G., Olomon J.P., et al. Aortic root geometry: pattern of differences between leaflets and sinuses of Valsalva. J Heart Valve Dis 8 (1999) 407-415
25. Rajamannan N.M., Subramaniam M., Springett M., et al. Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve. Circulation 105 (2002) 2260-2265
26. Rajamannan N.M., Subramaniam M., Stock S.R., et al. Atorvastatin inhibits calcification and enhances nitric oxide synthase production in the hypercholesterolaemic aortic valve. Heart 91 (2005) 806-810
27. Charest A., Pepin A., Shetty R., et al. Distribution of SPARC during neovascularization of degenerative aortic stenosis. Heart 92 (2006) 1844-1849
28. Mohler III E.R., Gannon F., Reynolds C., Zimmerman R., Keane M.G., and Kaplan F.S. Bone formation and inflammation in cardiac valves. Circulation 103 (2002) 1522-1528
29. Shetty R., Pepin A., Charest A., et al. Expression of bone-regulatory proteins in human valve allografts. Heart 92 (2006) 1303-1308
30. Rajamannan N.M., Subramaniam M., Caira F., Stock S.R., and Spelsberg T.C. Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway. Circulation 112 Suppl I (2005) I229-I234