Cadmium exposure induces expression of the HOXB8 gene in COS-7 cells

Toxicology in Vitro

Volumn 22, Issue 6, 2008, Pages 1447-1451

  Nakagawa, Kanako ^a   Lee, Myeong Jin ^a   Sasaki, Naoko ^a   Hayashi, Chiyo ^a   Nishio, Hisahide ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cadmium; Homeobox gene; HOXB8; Induction

Indexed keywords

CADMIUM; MESSENGER RNA; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN COS7; GENE EXPRESSION; GENE SILENCING; HOMEOBOX; NONHUMAN; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; CADMIUM; CARCINOGENS; CERCOPITHECUS AETHIOPS; COS CELLS; GENE EXPRESSION REGULATION; GENE SILENCING; GENES, HOMEOBOX; HUMANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 49149125134     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2008.04.010     Document Type: Article

References (26)

1. Abate C., Patel L., Rauscher III F.J., and Curran T. Redox regulation of fos and jun DNA-binding activity in vitro. Science 249 (1990) 1157-1161
2. Adams T.K., Saydam N., Steiner F., Schaffner W., and Freedman J.H. Activation of gene expression by metal-responsive signal transduction pathways. Environ. Health Persp. 110 Suppl. 5 (2002) 813-817
3. Blatt C., Aberdam D., Schwartz R., and Sachs L. DNA rearrangement of a homeobox gene in myeloid leukaemic cells. Embo J. 7 (1988) 4283-4290
4. Cantile M., Pettinato G., Procino A., Feliciello I., Cindolo L., and Cillo C. In vivo expression of the whole HOX gene network in human breast cancer. Eur. J. Cancer. 39 (2003) 257-264
5. Daftary G.S., and Taylor H.S. Endocrine regulation of HOX genes. Endocrine Rev. 27 (2006) 331-355
6. Elez D., Dundjerski J., and Matić G. Cadmium affects the redox state of rat liver glucocorticoid receptor. Cell Biol. Toxicol. 17 (2001) 169-177
7. Faiella A., Wernig M., Consalez G.G., Hostick U., Hofmann C., Hustert E., Boncinelli E., Balling R., and Nadeau J.H. A mouse model for valproate teratogenicity: parental effects, homeotic transformations, and altered HOX expression. Human Mol. Genet. 9 (2000) 227-236
8. Ferrando A.A., Armstrong S.A., Neuberg D.S., Sallan S.E., Silverman L.B., Korsmeyer S.J., and Look A.T. Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation. Blood 102 (2003) 262-268
9. Gehring W.J., and Hiromi Y. Homeotic genes and the homeobox. Annu. Rev. Genet. 20 (1986) 147-173
10. Hamer D.H. Metallothionein. Annu. Rev. Biochem. 55 (1986) 913-951
11. Hartwig A. Zinc finger proteins as potential targets for toxic metal ions: differential effects on structure and function. Antioxidant. Redox Signal. 3 (2001) 625-634
12. Kostic M.M., Ognjanovic B., Dimitrijevic S., Zikic R.V., Stajn A., Rosic G.L., and Zivkovic R.V. Cadmium-induced changes of antioxidant and metabolic status in red blood cells of rats: in vivo effects. Eur. J. Haematol. 51 (1993) 86-92
13. Krumlauf R. Hox genes in vertebrate development. Cell 78 (1994) 191-201
14. Lee G.S., Liao X., Cantor R.M., and Collins M.D. Interactive effects of cadmium and all-trans-retinoic acid on the induction of forelimb ectrodactyly in C57BL/6 mice. Birth Defects Res. A Clin. Mol. Teratol. 76 (2006) 19-28
15. Lee M.J., Nishio H., Ayaki H., Yamamoto M., and Sumino K. Upregulation of stress response mRNAs in COS-7 cells exposed to cadmium. Toxicology 174 (2002) 109-117
16. Leroy P., and De Robertis E.M. Effects of lithium chloride and retinoic acid on the expression of genes from the Xenopus laevis Hox 2 complex. Dev Dynam. 194 (1992) 21-32
17. Lopez R., Garrido E., Vazquez G., Pina P., Perez C., Alvarado I., and Salcedo M. A subgroup of HOX Abd-B gene is differentially expressed in cervical cancer. Int. J. Gynecol. Cancer. 16 (2006) 1289-1296
18. Lu H.C., Revelli J.P., Goering L., Thaller C., and Eichele G. Retinoid signaling is required for the establishment of a ZPA and for the expression of Hoxb-8, a mediator of ZPA formation. Development 124 (1997) 1643-1651
19. McGinnis W., and Krumlauf R. Homeobox genes and axial patterning. Cell 68 (1992) 283-302
20. Miller G.J., Miller H.L., van Bokhoven A., Lambert J.R., Werahera P.N., Schirripa O., Lucia M.S., and Nordeen S.K. Aberrant HOXC expression accompanies the malignant phenotype in human prostate. Cancer Res. 63 (2003) 5879-5888
21. Salovsky P., Shopova V., Dancheva V., and Marev R. Changes in antioxidant lung protection after single intra-tracheal cadmium acetate instillation in rats. Hum. Exp. Toxicol. 11 (1992) 217-222
22. St Andre J., Albanos K., and Reilly S. C-fos expression in the rat brain following lithium chloride-induced illness. Brain Res. 1135 (2007) 122-128
23. Vider B.Z., Zimber A., Hirsch D., Estlein D., Chastre E., Prevot S., Gespach C., Yaniv A., and Gazit A. Human colorectal carcinogenesis is associated with deregulation of homeobox gene expression. Biochem. Biophys. Res. Commun. 232 (1997) 742-748
24. Waisberg M., Joseph P., Hale B., and Beyersmann D. Molecular and cellular mechanisms of cadmium carcinogenesis. Toxicology 192 (2003) 95-117
25. Wang Z., and Templeton D.M. Induction of c-fos proto-oncogene in mesangial cells by cadmium. J. Biol. Chem. 273 (1998) 73-79
26. Webster W. The teratology and developmental toxicity of cadmium (1990), Plenum Press, New York pp. 255-282