Cyclodextrin polysulphate protects articular cartilage in experimental lapine knee osteoarthritis

Osteoarthritis and Cartilage

Volumn 16, Issue 9, 2008, Pages 986-993

  Groeneboer, S ^a   Pastoureau, P ^b   Vignon, E ^c   Vander Cruyssen, B ^a   Elewaut, D ^a   Verbruggen, G ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b INSTITUT DE RECHERCHES SERVIER   (France)

^c UNIVERSITÉ LYON 1   (France)

Author keywords

ACLT model; Cartilage; Cyclodextrin polysulphate; DMOAD

Indexed keywords

CYCLODEXTRIN; CYCLODEXTRIN POLYSULFATE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE DEGENERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; HISTOCHEMISTRY; HISTOPATHOLOGY; IN VIVO STUDY; KNEE OSTEOARTHRITIS; MALE; NONHUMAN; OSTEOPHYTE; PRIORITY JOURNAL; RABBIT; RANDOMIZATION; WEIGHT GAIN;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; CARTILAGE, ARTICULAR; CHONDROCYTES; CYCLODEXTRINS; INJECTIONS, INTRAMUSCULAR; KNEE JOINT; MALE; OSTEOARTHRITIS, KNEE; RABBITS; TREATMENT OUTCOME;

EID: 49149124748     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2008.01.005     Document Type: Article

References (47)

1. Momburg M., Stuhlsatz H.W., Vogeli H., Vojtisek O., Eylau O., and Greiling H. Clinical chemical changes in the synovial fluid following intra-articular injection of a glycosaminoglycan polysulfate (proceedings). Z Rheumatol 35 Suppl 4 (1976) s389-s390
2. Nevo Z., and Dorfman A. Stimulation of chondromucoprotein synthesis in chondrocytes by extracellular chondromucoprotein. Proc Natl Acad Sci U S A 69 (1972) 2069-2072
3. Kosher R.A., Lash J.W., and Minor R.R. Environmental enhancement of in vitro chondrogenesis. IV. Stimulation of somite chondrogenesis by exogenous chondromucoprotein. Dev Biol 35 (1973) 210-220
4. Schwartz N.B., and Dorfman A. Stimulation of chondroitin sulfate proteoglycan production by chondrocytes in monolayer. Connect Tissue Res 3 (1975) 115-122
5. Verbruggen G., and Veys E.M. Influence of sulphated glycosaminoglycans upon proteoglycan metabolism of the synovial lining cells. Acta Rhumatol Belg 1 (1977) 75-92
6. Verbruggen G., and Veys E.M. Influence of an oversulphated heparinoid upon hyaluronate metabolism of the human synovial cell in vivo. J Rheumatol 6 (1979) 554-561
7. Verbruggen G, Veys EM. Proteoglycan metabolism of connective tissue cells. An in vitro technique and its relevance to in vivo conditions. Amsterdam; 1982.
8. Clegg D.O., Reda D.J., Harris C.L., Klein M.A., O'Dell J.R., Hooper M.M., et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 354 (2006) 795-808
9. Leeb B.F., Schweitzer H., Montag K., and Smolen J.S. A metaanalysis of chondroitin sulfate in the treatment of osteoarthritis. J Rheumatol 27 (2000) 205-211
10. Uebelhart D., Malaise M., Marcolongo R., DeVathaire F., Piperno M., Mailleux E., et al. Intermittent treatment of knee osteoarthritis with oral chondroitin sulfate: a one-year, randomized, double-blind, multicenter study versus placebo. Osteoarthritis Cartilage 12 (2004) 269-276
11. Uebelhart D., Thonar E.J., Delmas P.D., Chantraine A., and Vignon E. Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot study. Osteoarthritis Cartilage 6 Suppl A (1998) 39-46
12. Verbruggen G., Goemaere S., and Veys E.M. Chondroitin sulfate: S/DMOAD (structure/disease modifying anti-osteoarthritis drug) in the treatment of finger joint OA. Osteoarthritis Cartilage 6 Suppl A (1998) 37-38
13. Verbruggen G., Goemaere S., and Veys E.M. Systems to assess the progression of finger joint osteoarthritis and the effects of disease modifying osteoarthritis drugs. Clin Rheumatol 21 (2002) 231-243
14. Verbruggen G., Cornelissen M., Elewaut D., Broddelez C., De Ridder L., and Veys E.M. Influence of polysulfated polysaccharides on aggrecans synthesized by differentiated human articular chondrocytes. J Rheumatol 26 (1999) 1663-1671
15. Francis D.J., Hutadilok N., Kongtawelert P., and Ghosh P. Pentosan polysulphate and glycosaminoglycan polysulphate stimulate the synthesis of hyaluronan in vivo. Rheumatol Int 13 (1993) 61-64
16. Verbruggen G., and Veys E.M. Intra-articular injection pentosanpolysulphate results in increased hyaluronan molecular weight in joint fluid. Clin Exp Rheumatol 10 (1992) 249-254
17. Rogachefsky R.A., Dean D.D., Howell D.S., and Altman R.D. Treatment of canine osteoarthritis with insulin-like growth factor-1 (IGF-1) and sodium pentosan polysulfate. Osteoarthritis Cartilage 1 (1993) 105-114
18. Ghosh P. The pathobiology of osteoarthritis and the rationale for the use of pentosan polysulfate for its treatment. Semin Arthritis Rheum 28 (1999) 211-267
19. Malemud C.J., Goldberg V.M., and Moskowitz R.W. Pathological, biochemical and experimental therapeutic studies in meniscectomy models of osteoarthritis in the rabbit - its relationship to human joint pathology. Br J Clin Pract Suppl 43 (1986) 21-31
20. Verdonk P., Wang J., Groeneboer S., Broddelez C., Elewaut D., Veys E.M., et al. Cyclodextrin polysulphates repress IL-1 and promote the accumulation of chondrocyte extracellular matrix. Osteoarthritis Cartilage 13 (2005) 887-895
21. Pitha J., Mallis L.M., Lamb D.J., Irie T., and Uekama K. Cyclodextrin sulfates: characterization as polydisperse and amorphous mixtures. Pharm Res 8 (1991) 1151-1154
22. Chen F.T., Shen G., and Evangelista R.A. Characterization of highly sulfated cyclodextrins. J Chromatogr A 924 1-2 (2001) 523-532
23. Yoshioka M., Coutts R.D., Amiel D., and Hacker S.A. Characterization of a model of osteoarthritis in the rabbit knee. Osteoarthritis Cartilage 4 (1996) 87-98
24. Ayral X., Dougados M., Listrat V., Bonvarlet J.P., Simonnet J., Poiraudeau S., et al. Chondroscopy: a new method for scoring chondropathy. Semin Arthritis Rheum 22 (1993) 289-297
25. Colombo C., Butler M., O'Byrne E., Hickman L., Swartzendruber D., Selwyn M., et al. A new model of osteoarthritis in rabbits. I. Development of knee joint pathology following lateral meniscectomy and section of the fibular collateral and sesamoid ligaments. Arthritis Rheum 26 (1983) 875-886
26. Kikuchi T., Yamada H., and Shimmei M. Effect of high molecular weight hyaluronan on cartilage degeneration in a rabbit model of osteoarthritis. Osteoarthritis Cartilage 4 (1996) 99-110
27. Fitz M., Laird N., and Ware J. Applied Longitudinal Analysis (2004), Wiley and Sons, New Jersey, USA
28. Smith R.L., Allison A.C., and Schurman D.J. Induction of articular cartilage degradation by recombinant interleukin 1 alpha and 1 beta. Connect Tissue Res 18 (1989) 307-316
29. Smith R.J., Rohloff N.A., Sam L.M., Justen J.M., Deibel M.R., and Cornette J.C. Recombinant human interleukin-1 alpha and recombinant human interleukin-1 beta stimulate cartilage matrix degradation and inhibit glycosaminoglycan synthesis. Inflammation 13 (1989) 367-382
30. Page Thomas D.P., King B., Stephens T., and Dingle J.T. In vivo studies of cartilage regeneration after damage induced by catabolin/interleukin-1. Ann Rheum Dis 50 (1991) 75-80
31. Tetlow L.C., Adlam D.J., and Woolley D.E. Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: associations with degenerative changes. Arthritis Rheum 44 (2001) 585-594
32. Nietfeld J.J., Wilbrink B., Helle M., van Roy J.L., den Otter W., Swaak A.J., et al. Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage. Arthritis Rheum 33 (1990) 1695-1701
33. Guerne P.A., Carson D.A., and Lotz M. IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro. J Immunol 144 (1990) 499-505
34. Malfait A.M., Verbruggen G., Veys E.M., Lambert J., De Ridder L., and Cornelissen M. Comparative and combined effects of interleukin 6, interleukin 1 beta, and tumor necrosis factor alpha on proteoglycan metabolism of human articular chondrocytes cultured in agarose. J Rheumatol 21 (1994) 314-320
35. Yuen S.N., Folkman J., Weisz P.B., Joullie M.M., and Ewing W.R. Affinity of fibroblast growth factors for beta-cyclodextrin tetradecasulfate. Anal Biochem 185 (1990) 108-111
36. Weiner D.B., Williams W.V., Weisz P.B., and Greene M.I. Synthetic cyclodextrin derivatives inhibit HIV infection in vitro. Pathobiology 60 (1992) 206-212
37. Sakairi N., Kuzuhara H., Okamoto T., and Yajima M. Synthesis and biological evaluation of 2-amino-2-deoxy- and 6-amino-6-deoxy-cyclomaltoheptaose polysulfates as synergists for angiogenesis inhibition. Bioorg Med Chem 4 (1996) 2187-2192
38. Moriya T., Kurita H., Matsumoto K., Otake T., Mori H., Morimoto M., et al. Potent inhibitory effect of a series of modified cyclodextrin sulfates (mCDS) on the replication of HIV-1 in vitro. J Med Chem 34 (1991) 2301-2304
39. Setton L.A., Elliott D.M., and Mow V.C. Altered mechanics of cartilage with osteoarthritis: human osteoarthritis and an experimental model of joint degeneration. Osteoarthritis Cartilage 7 (1999) 2-14
40. Sabatini M., Lesur C., Thomas M., Chomel A., Anract P., de Nanteuil G., et al. Effect of inhibition of matrix metalloproteinases on cartilage loss in vitro and in a guinea pig model of osteoarthritis. Arthritis Rheum 52 (2005) 171-180
41. Malemud C.J. Changes in proteoglycans in osteoarthritis: biochemistry, ultrastructure and biosynthetic processing. J Rheumatol Suppl 27 (1991) 60-62
42. Leroux M.A., Cheung H.S., Bau J.L., Wang J.Y., Howell D.S., and Setton L.A. Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization. Osteoarthritis Cartilage 9 (2001) 633-640
43. Van Looy S., Cruyssen B.V., Meeus J., Wyns B., Westhovens R., Durez P., et al. Prediction of dose escalation for rheumatoid arthritis patients under infliximab treatment. Eng Appl Artif Intell 19 (2006) 819-828
44. Agarwal S., Deschner J., Long P., Verma A., Hofman C., Evans C.H., et al. Role of NF-kappaB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals. Arthritis Rheum 50 (2004) 3541-3548
45. Islam N., Haqqi T.M., Jepsen K.J., Kraay M., Welter J.F., Goldberg V.M., et al. Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-alpha, inducible nitric oxide synthase, p53, c-myc, and bax-alpha, and suppression of bcl-2. J Cell Biochem 87 (2002) 266-278
46. Redman S.N., Dowthwaite G.P., Thomson B.M., and Archer C.W. The cellular responses of articular cartilage to sharp and blunt trauma. Osteoarthritis Cartilage 12 (2004) 106-116
47. Müller W., Panse P., Brand S., and Staubli A. In vivo study of the distribution, affinity for cartilage and metabolism of glycosaminoglycan polysulphate (GAGPS, Arteparon). Z Rheumatol 42 (1983) 355-361