Cyclodextrin polysulphates repress IL-1 and promote the accumulation of chondrocyte extracellular matrix

Osteoarthritis and Cartilage

Volumn 13, Issue 10, 2005, Pages 887-895

  Verdonk, P ^a   Wang, J ^a   Groeneboer, S ^a   Broddelez, C ^a   Elewaut, D ^a   Veys, E M ^a   Verbruggen, Gust ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Aggrecan; Chondrocytes; Cyclodextrin polysulphate; IL 1

Indexed keywords

AGGRECAN; BETA CYCLODEXTRIN; COLLAGEN TYPE 2; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2 RECEPTOR; SOMATOMEDIN C RECEPTOR;

ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CATABOLITE REPRESSION; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL LABELING; CELL MEMBRANE; CELL METABOLISM; CELL PERMEABILIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; EXTRACELLULAR MATRIX; FEMUR CONDYLE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KNEE OSTEOARTHRITIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN SYNTHESIS REGULATION; STATISTICAL SIGNIFICANCE;

AGGRECANS; AUTOCRINE COMMUNICATION; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; CYCLODEXTRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; LECTINS, C-TYPE; PROTEOGLYCANS; RECEPTOR, IGF TYPE 1;

EID: 26444516519     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2005.02.014     Document Type: Article

References (54)

1. Z. Nevo A.L. Horwitz A. Dorfman Synthesis of chondromucoprotein by chondrocytes in suspension culture Dev Biol 28 1972 219-28
2. Z. Nevo A. Dorfman Stimulation of chondromucoprotein synthesis in chondrocytes by extracellular chondromucoprotein Proc Natl Acad Sci U S A 69 1972 2069-72
3. R.A. Kosher J.W. Lash R.R. Minor Environmental enhancement of in vitro chondrogenesis Dev Biol 35 1973 210-20
4. O.W. Wiebkin H. Muir Factors affecting the biosynthesis of sulphated glycosaminoglycans by chondrocytes in short-time maintenance culture isolated from adult tissue. In: E. Kulonen J. Pikkaraininen, Eds. Biology of Fibroblast 1973 Acad Press London 231-52
5. P. Ghosh M. Smith C. Wells Second-line agents in osteoarthritis. In: J.S. Dixon D.E. Furst, Eds. Second Line Agents in the Treatment of Rheumatic Diseases 1992 Marcel Dekker New York 363-427
6. P. Ghosh The pathobiology of osteoarthritis and the rationale for the use of pentosan polysulfate for its treatment Semin Arthritis Rheum 28 1999 211-67
7. N.B. Schwartz A. Dorfman Stimulation of chondroitin sulfate proteoglycan production by chondrocytes in monolayer Connect Tissue Res 3 1975 115-22
8. G. Verbruggen E.M. Veys Influence of sulphated glycosaminoglycans upon proteoglycan metabolism of the synovial lining cells Acta Rheumatol 1 1977 75-92
9. G. Verbruggen E.M. Veys Influence of an oversulphated heparinoid upon hyaluronate metabolism of the human synovial cell in vivo J Rheumatol 6 1979 554-61
10. D.J. Francis N. Hutadilok P. Kongtawelert P. Ghosh Pentosanpolysulphate and glycosaminoglycan polysulphate stimulate the synthesis of hyaluronan in vivo Rheumatol Int 13 1993 61-64
11. G. Verbruggen E.M. Veys Intraarticular injection of pentosanpolysulphate results in increased hyaluronan molecular weight in joint fluid Clin Exp Rheumatol 10 1992 249-54
12. G. Verbruggen E.M. Veys Proteoglycan metabolism of connective tissue cells. An in vitro technique and its relevance to in vivo conditions. In: G. Verbruggen E.M. Veys, Eds. Degenerative Joints 1982 Excerpta Medica Amsterdam 113-29
13. G. Verbruggen M. Cornelissen D. Elewaut C. Broddelez L. De Ridder E.M. Veys Influence of polysulfated polysaccharides on aggrecans synthesised by differentiated human articular chondrocytes J Rheumatol 26 1999 1663-71
14. A.R. Poole Cartilage in health and disease. In: W.J. Koopmam, Ed. Arthritis and Allied Conditions: A Textbook of Rheumatology 1997 Williams and Wilkins Baltimore 255-308
15. R.D. Altman M.C. Hochberg R.W. Moskowitz T.J. Schnitzer Recommendations for the medical management of osteoarthritis of the hip and knee. 2000 update. ACR subcommittee on osteoarthritis guidelines Arthritis Rheum 43 2000 1905-15
16. T. Astrup I.B. Galsmar M. Volkert Polysaccharide sulfuric acids as anticoagulants Acta Physiol Scand 8 1944 215-26
17. M. Cornelissen G. Verbruggen A.M. Malfait E.M. Veys C. Broddelez L. De Ridder The study of representative populations of native aggrecan aggregates synthesized by human chondrocytes in vitro J Tissue Culture Methods 15 1993 139-46
18. J. Guo G.W. Jourdian D.K. MacCallum Culture and growth characteristics of chondrocytes encapsulated in alginate beads Connect Tissue Res 9 1989 277-97
19. J. Wang D. Elewaut E.M. Veys G. Verbruggen IGF-1-induced IL-1RII overrules IL-1 activity and controls the homeostasis of the extracellular matrix of cartilage Arthritis Rheum 48 2003 1281-91
20. G. Verbruggen M. Cornelissen K.F. Almqvist L. Wang D. Elewaut C. Broddelez et al. Influence of aging on the synthesis and morphology of the aggrecans synthesized by differentiated human articular chondrocytes Osteoarthritis Cartilage 8 2000 170-9
21. H.J. Häuselmann M.B. Aydelotte B.L. Schumacher K.E. Kuettner S.H. Gitelis E.J.-M.A. Thonar Synthesis and turnover of proteoglycans by human and bovine adult articular chondrocytes cultured in alginate beads Matrix 12 1992 116-29
22. L. Wang G. Verbruggen K.F. Almqvist D. Elewaut C. Broddelez E.M. Veys Flow cytometric analysis of the human articular chondrocyte phenotype Osteoarthritis Cartilage 9 2001 73-84
23. M.N. Kronick P.D. Grossman Immunoassay techniques with fluorescent phycobiliprotein conjugates Clin Chem 29 1983 1582-6
24. L. Wang K.F. Almqvist C. Broddelez E.M. Veys G. Verbruggen Evaluation of chondrocyte cell-associated matrix metabolism by flow cytometry Osteoarthritis Cartilage 9 2001 454-62
25. M.G. Chambers M.T. Bayliss R.M. Mason Chondrocyte cytokine and growth factor expression in murine osteoarthritis Osteoarthritis Cartilage 5 1997 301-8
26. V. Moos S. Fickert B. Muller U. Weber J. Sieper Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage J Rheumatol 26 1999 870-9
27. C. Colombo M. Butler L. Hickman M. Selwyn J. Chart B. Steinetz A new model of osteoarthritis in rabbits. II. Evaluation of anti-osteoarthritic effects of selected antirheumatic drugs administered systemically Arthritis Rheum 26 1983 1132-1139
28. M. Butler C. Colombo L. Hickman E. O'Byrne R. Steele B. Steinetz et al. A new model of osteoarthritis in rabbits. III. Evaluation of anti-osteoarthritic effects of selected drugs administered intraarticularly Arthritis Rheum 26 1983 1380-6
29. B.V. Shlopov M.L. Gumanovskaya K.A. Hasty Autocrine regulation of collagenase 3 (matrix metalloproteinase 13) during osteoarthritis Arthritis Rheum 43 2000 195-205
30. M.A. Pratta T.M. Di Meo D.M. Ruhl E.C. Arner Effect of interleukin-1-beta and tumor necrosis factor-alpha on cartilage proteoglycan metabolism in vitro Agents Actions 27 1989 250-3
31. S.N. Redman G.P. Dowthwaite B.M. Thomson C.W. Archer The cellular responses of articular cartilage to sharp and blunt trauma Osteoarthritis Cartilage 12 2004 106-16
32. N. Islam T.M. Haqqi K.J. Jepsen M. Kraay J.F. Welter V.M. Goldberg et al. Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-alpha, inducible nitric oxide synthase, p53, c-myc, and bax-alpha, and suppression of bcl-2 J Cell Biochem 87 2002 266-78
33. H.J. Häuselmann R.J. Fernandes S.S. Mok T.M. Schmid J.A. Block M.B. Aydelotte et al. Phenotypic stability of bovine articular chondrocytes after long-term culture in alginate beads J Cell Sci 107 1994 17-27
34. F. Lemare N. Steimberg C. Le Griel S. Demignot M. Adolphe Dedifferentiated chondrocytes cultured in alginate beads: Restoration of the differentiated phenotype and of the metabolic responses J Cell Physiol 176 1998 303-13
35. C.B. Little P. Ghosh Variation in proteoglycan metabolism by articular chondrocytes in different joint regions is determined by post-natal mechanical loading Osteoarthritis Cartilage 5 1997 49-62
36. R.F. Loeser G. Shanker C.S. Carlson J.F. Gardin B.J. Shelton W.E. Sonntag Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: Studies in a non-human primate model of naturally occurring disease Arthritis Rheum 43 2000 2110-20
37. J. Wang P. Verdonk D. Elewaut E.M. Veys G. Verbruggen Homeostasis of the extracellular matrix of normal and osteoarthritic human articular cartilage chondrocytes in vitro Osteoarthritis Cartilage 11 2003 801-9
38. A. Rossi I. Kaitila W.R. Wilcox D.L. Rimoin B. Steinmann G. Cetta et al. Proteoglycan sulfation in cartilage and cell cultures from patients with sulfate transporter chondrodysplasias: Relationship to clinical severity and indications on the role of intracellular sulfate production Matrix Biol 17 1998 361-9
39. R 1982 Eular Publisher Basle 50-67
40. H. Nishikawa I. Mori J. Umemoto Influences of sulphated glycosaminoglycans on biosynthesis of hyaluronic acid in rabbit knee synovium Arch Biochem Biophys 240 1985 146-53
41. A.A. Farooqui Purification of enzymes by heparin-sepharose affinity chromatography J Chromatogr 184 1980 335-45
42. A.A. Pineda Methods for selective removal of plasma constituents Prog Clin Biol Res 106 1982 361-73
43. J.A. Tyler Articular cartilage cultured with catabolin (pig interleukin 1) synthesizes a decreased number of normal proteoglycan molecules Biochem J 227 1985 869-78
44. D. Taskiran M. Stefanovic-Racic H. Georgescu C. Evans Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1 Biochem Biophys Res Commun 200 1994 142-8
45. H. Greiling M. Kaneko Inhibition of lysosomal enzymes by glycosaminoglycanpolysulfate. Therapy of chronic joint diseases using compounds with antidegenerative properties; biochemistry Arzneimittelforschung 23 1973 593-7
46. K. Kruze K. Fehr A. Boni Effect of antirheumatic drugs on cathepsin B1 from bovine spleen Z Rheumatol 35 1976 95-102
47. A. Baici P. Salgam K. Fehr A. Boni Inhibition of human elastase from polymorphonuclear leucocytes by a glycosaminoglycan polysulfate (Arteparon) Biochem Pharmacol 29 1980 1723-7
48. R.W. Stephens E.A. Walton P. Ghosh T.K. Taylor M. Gramse K. Havemann A radioassay for proteolytic cleavage of isolated cartilage proteoglycan. 2. Inhibition of human leukocyte elastase and cathepsin G by anti-inflammatory drugs Arzneimittelforschung 30 1980 2108-12
49. J.L. Andrews P. Ghosh A. Lentini B. Ternai The interaction of pentosan polysulphate (SP54) with human neutrophil elastase and connective tissue matrix components Chem Biol Interact 47 1983 157-73
50. P.D. Clegg M.D. Jones S.D. Carter The effect of drugs commonly used in the treatment of equine articular disorders on the activity of equine matrix metalloproteinase-2 and 9 J Vet Pharmacol Ther 21 1998 406-13
51. P.B. Halverson H.S. Cheung J. Struve D.J. McCarty Suppression of active collagenase from calcified lapine synovium by Arteparon J Rheumatol 14 1987 1013-7
52. T. Sadowski J. Steinmeyer Effects of polysulfated glycosaminoglycan and triamcinolone acetonid on the production of proteinases and their inhibitors by IL-1alpha treated articular chondrocytes Biochem Pharmacol 64 2002 217-27
53. A.M. Malfait G. Verbruggen E.M. Veys J. Lambert L. De Ridder M. Cornelissen Comparative and combined effects of interleukin 6, interleukin 1β, and tumor necrosis factor α on proteoglycan metabolism of human articular chondrocytes cultured in agarose J Rheumatol 21 1994 314-20
54. Y.E. Henrotin D.D. De Groote A.H. Labasse S.E. Gaspar S.X. Zheng V.G. Geenen et al. Effects of exogenous IL-1 beta, TNF alpha, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes Osteoarthritis Cartilage 4 1996 163-73