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Volumn 28, Issue 4, 1999, Pages 211-267

The pathobiology of osteoarthritis and the rationale for the use of pentosan polysulfate for its treatment

Author keywords

Osteoarthritis; Pentosan polysulfate; Structural modifying osteoarthritis drugs (SMOADs); Treatment

Indexed keywords

PENTOSAN POLYSULFATE;

EID: 0032964167     PISSN: 00490172     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-0172(99)80021-3     Document Type: Article
Times cited : (134)

References (390)
  • 1
    • 0002491064 scopus 로고
    • Arthritic and other musculoskeletal disease
    • Scott J.C. Hochberg M.C. Arthritic and other musculoskeletal disease Brownson R.C. Remington P.L. Davis J.L. Chronic disease epidemiology 1993 American Public Health Association Washington, DC
    • (1993)
    • Scott, J.C.1    Hochberg, M.C.2
  • 2
    • 0029793844 scopus 로고    scopus 로고
    • The occurrence of osteoarthritis outside Europe
    • Croft P. The occurrence of osteoarthritis outside Europe Ann Rheum Dis 55 1996 661 664
    • (1996) Ann Rheum Dis , vol.55 , pp. 661-664
    • Croft, P.1
  • 3
    • 0023708367 scopus 로고
    • Epidemiology of hip and knee osteoarthritis
    • Felson D.T. Epidemiology of hip and knee osteoarthritis Epidermal Rev 10 1988 1 28
    • (1988) Epidermal Rev , vol.10 , pp. 1-28
    • Felson, D.T.1
  • 4
    • 0029792745 scopus 로고    scopus 로고
    • Occurrence of osteoarthritis of the peripheral joints in European populations
    • Petersson I.F. Occurrence of osteoarthritis of the peripheral joints in European populations Ann Rheum Dis 55 1996 659 661
    • (1996) Ann Rheum Dis , vol.55 , pp. 659-661
    • Petersson, I.F.1
  • 6
    • 84988220928 scopus 로고    scopus 로고
    • Assessing costeffectiveness analyses in rheumatoid arthritis and osteoarthritis
    • Ruchlin H.S. Elkin E.B. Paget S.A. Assessing costeffectiveness analyses in rheumatoid arthritis and osteoarthritis Arthritis Care Research 10 1997 413 421
    • (1997) Arthritis Care Research , vol.10 , pp. 413-421
    • Ruchlin, H.S.1    Elkin, E.B.2    Paget, S.A.3
  • 7
    • 0022465236 scopus 로고
    • Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee
    • Altman R. Asch E. Bloch D. Bole G. Borestein D. Brandt K. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee Arthritis Rheum 29 1986 1039 1049
    • (1986) Arthritis Rheum , vol.29 , pp. 1039-1049
    • Altman, R.1    Asch, E.2    Bloch, D.3    Bole, G.4    Borestein, D.5    Brandt, K.6
  • 8
    • 0025667288 scopus 로고
    • The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand
    • Altman R. Alarcon G. Appelrouth D. Bloch D. Borenstein D. Brandt K. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand Arthritis Rheum 33 1990 1601 1610
    • (1990) Arthritis Rheum , vol.33 , pp. 1601-1610
    • Altman, R.1    Alarcon, G.2    Appelrouth, D.3    Bloch, D.4    Borenstein, D.5    Brandt, K.6
  • 9
    • 0027461277 scopus 로고
    • Does osteoarthrosis depend on growth of the mineralized layer of cartilage
    • Hulth A. Does osteoarthrosis depend on growth of the mineralized layer of cartilage Clin Orthop 287 1993 19 24
    • (1993) Clin Orthop , vol.287 , pp. 19-24
    • Hulth, A.1
  • 10
    • 0030926357 scopus 로고    scopus 로고
    • The involvement of subchondral mineralized tissues in osteoarthrosis: quantitative microscopic evidence
    • Burr D.B. Schaffler M.B. The involvement of subchondral mineralized tissues in osteoarthrosis: quantitative microscopic evidence Microsc Res 37 1997 343 357
    • (1997) Microsc Res , vol.37 , pp. 343-357
    • Burr, D.B.1    Schaffler, M.B.2
  • 11
    • 0030954566 scopus 로고    scopus 로고
    • Cartilage and subchondral bone interaction in osteoarthrosis of human knee joint: a histological and histomorphometric study
    • Matsui H. Shimizu M. Tsuji H. Cartilage and subchondral bone interaction in osteoarthrosis of human knee joint: a histological and histomorphometric study Macrosc Res 37 1997 333 342
    • (1997) Macrosc Res , vol.37 , pp. 333-342
    • Matsui, H.1    Shimizu, M.2    Tsuji, H.3
  • 12
    • 0002231568 scopus 로고
    • Pathology and pathogenesis of osteoarthritis
    • Sokoloff L. Pathology and pathogenesis of osteoarthritis McCarty D. Arthritis and Allied Conditions 1979 Lea & Febiger Philadelphia 1135 1153
    • (1979) , pp. 1135-1153
    • Sokoloff, L.1
  • 13
    • 0022261467 scopus 로고
    • Histomorphometric changes in the trabecular structure of a selected stress region in the femur in patients with osteoarthritis and fracture of the femoral neck
    • Fazzalari N.L. Darracott J. Vernon-Roberts B. Histomorphometric changes in the trabecular structure of a selected stress region in the femur in patients with osteoarthritis and fracture of the femoral neck Bone 6 1985 125 133
    • (1985) Bone , vol.6 , pp. 125-133
    • Fazzalari, N.L.1    Darracott, J.2    Vernon-Roberts, B.3
  • 14
    • 0001009537 scopus 로고
    • Intraosseous thrombosis in ischemic necrosis of bone and osteoarthritis
    • Cheras P.A. Freemont A.J. Sikorski J.M. Intraosseous thrombosis in ischemic necrosis of bone and osteoarthritis Osteoarthritis Cart 1 1993 219 232
    • (1993) Osteoarthritis Cart , vol.1 , pp. 219-232
    • Cheras, P.A.1    Freemont, A.J.2    Sikorski, J.M.3
  • 15
    • 0025194451 scopus 로고
    • Subchondral avascular necrosis: a common cause of arthritis
    • Bullough P.G. DiCarlo E.F. Subchondral avascular necrosis: a common cause of arthritis Ann Rheum Dis 49 1990 412 420
    • (1990) Ann Rheum Dis , vol.49 , pp. 412-420
    • Bullough, P.G.1    DiCarlo, E.F.2
  • 16
    • 0023263982 scopus 로고
    • The intraosseous circulation and pathogenesis of osteoarthritis
    • Kiaer T. The intraosseous circulation and pathogenesis of osteoarthritis Med Sci Res 15 1987 759 763
    • (1987) Med Sci Res , vol.15 , pp. 759-763
    • Kiaer, T.1
  • 17
    • 0023111835 scopus 로고
    • The pathogenesis of osteoarthritis of the hip: evidence for primary osteocyte death
    • Wong S.Y.P. Evans R.A. Needs C. Dunstan C.R. Hills E. Garvan J. The pathogenesis of osteoarthritis of the hip: evidence for primary osteocyte death Clin Orthop 214 1987 305 312
    • (1987) Clin Orthop , vol.214 , pp. 305-312
    • Wong, S.Y.P.1    Evans, R.A.2    Needs, C.3    Dunstan, C.R.4    Hills, E.5    Garvan, J.6
  • 18
    • 0023990691 scopus 로고
    • Subchondral P02, pCO2, pressure, pH, and lactate in human osteoarthritis of the hip
    • 2, pressure, pH, and lactate in human osteoarthritis of the hip Clin Orthop 229 1988 149 155
    • (1988) Clin Orthop , vol.229 , pp. 149-155
    • Kiaer, T.1    Gronlund, J.2    Sorensen, K.H.3
  • 19
    • 0022490441 scopus 로고
    • Intraosseous concentrations of lactate in late stage of osteoarthritis of the hip
    • Kiaer T. Intraosseous concentrations of lactate in late stage of osteoarthritis of the hip IRCS Med Sci 14 1986 591 592
    • (1986) IRCS Med Sci , vol.14 , pp. 591-592
    • Kiaer, T.1
  • 20
    • 0028915328 scopus 로고
    • Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis
    • Glant T.T. Fülöp C. Cs-Szabó G. Buzas E. Ragasa D. Mikecz K. Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis Scand J Rheumatol 24 1995 43 49
    • (1995) Scand J Rheumatol , vol.24 , pp. 43-49
    • Glant, T.T.1    Fülöp, C.2    Cs-Szabó, G.3    Buzas, E.4    Ragasa, D.5    Mikecz, K.6
  • 21
    • 0022921770 scopus 로고
    • Collagen antibodies in rheumatoid arthritis: significance of antibodies to denatured collagen and their association with HLA-DR4
    • Rowley M. Tait B. Mackay I.R. Cunningham T. Phillips B. Collagen antibodies in rheumatoid arthritis: significance of antibodies to denatured collagen and their association with HLA-DR4 Arthritis Rheum 29 1986 174 184
    • (1986) Arthritis Rheum , vol.29 , pp. 174-184
    • Rowley, M.1    Tait, B.2    Mackay, I.R.3    Cunningham, T.4    Phillips, B.5
  • 22
    • 0025169007 scopus 로고
    • Variability in the immunochemical quantification of keratan sulfate in human and bovine cartilage proteoglycans
    • Seibel M.J. Jelsma R. Saed-Nejad F. Ratcliffe A. Variability in the immunochemical quantification of keratan sulfate in human and bovine cartilage proteoglycans Biochem Soc Trans 18 1990 969 970
    • (1990) Biochem Soc Trans , vol.18 , pp. 969-970
    • Seibel, M.J.1    Jelsma, R.2    Saed-Nejad, F.3    Ratcliffe, A.4
  • 23
    • 0023576229 scopus 로고
    • Arthroscopic and immunohisto-logic characterization of knee-joint synovitis in osteoarthritis
    • Lindblad S. Hedfors E. Arthroscopic and immunohisto-logic characterization of knee-joint synovitis in osteoarthritis Arthritis Rheum 30 1987 1081 1088
    • (1987) Arthritis Rheum , vol.30 , pp. 1081-1088
    • Lindblad, S.1    Hedfors, E.2
  • 24
    • 0020014094 scopus 로고
    • Osteoarthritis: an arthritis?
    • Soren A. Osteoarthritis: an arthritis? Z Rheumatol 41 1982 1 6
    • (1982) Z Rheumatol , vol.41 , pp. 1-6
    • Soren, A.1
  • 25
    • 0023881194 scopus 로고
    • The synovial membrane in osteoarthritis: a histological study including the characterization of the cellular infiltrate present in inflammatoryosteoarthritis using monoclonal antibodies
    • Revell P.A. Mayston V. Lalor P. Mapp P. The synovial membrane in osteoarthritis: a histological study including the characterization of the cellular infiltrate present in inflammatoryosteoarthritis using monoclonal antibodies Ann Rheum Dis 47 1988 300 307
    • (1988) Ann Rheum Dis , vol.47 , pp. 300-307
    • Revell, P.A.1    Mayston, V.2    Lalor, P.3    Mapp, P.4
  • 26
    • 0031047265 scopus 로고    scopus 로고
    • Synovial membrane inflammation and cytokine production in patients with early osteoarthritis
    • Smith M.D. Triantafillou S. Parker A. Youssef P.P. Coleman M. Synovial membrane inflammation and cytokine production in patients with early osteoarthritis J Rheumatol 24 1997 365 371
    • (1997) J Rheumatol , vol.24 , pp. 365-371
    • Smith, M.D.1    Triantafillou, S.2    Parker, A.3    Youssef, P.P.4    Coleman, M.5
  • 27
    • 0000438442 scopus 로고    scopus 로고
    • Structure and function of synoviocytes
    • Müller-Ladner U. Gay R.E. Gay S. Structure and function of synoviocytes Koopman W.J. Arthritis and allied conditions 1997 Williams & Wilkins Baltimore 243
    • (1997) , pp. 243
    • Müller-Ladner, U.1    Gay, R.E.2    Gay, S.3
  • 28
    • 0028339814 scopus 로고
    • The nature and origins of synovium: experimental approaches to the study of synoviocyte differentiation
    • Edwards J.C.W. The nature and origins of synovium: experimental approaches to the study of synoviocyte differentiation J Anat 184 1994 493 501
    • (1994) J Anat , vol.184 , pp. 493-501
    • Edwards, J.C.W.1
  • 29
    • 0001793942 scopus 로고
    • The physical properties of synovial fluid and the special role of hyaluronic acid
    • Balazs E.A. The physical properties of synovial fluid and the special role of hyaluronic acid Helfet A.J. Disorders of the knee 1982 Lippincott Philadelphia 61 74
    • (1982) , pp. 61-74
    • Balazs, E.A.1
  • 31
    • 0025897125 scopus 로고
    • Proteinase-mediated cartilage degradation in osteoarthritis
    • Dean D.D. Proteinase-mediated cartilage degradation in osteoarthritis Semin Arthritis Rheum 20 1991 2 11
    • (1991) Semin Arthritis Rheum , vol.20 , pp. 2-11
    • Dean, D.D.1
  • 32
    • 0023190673 scopus 로고
    • Free radicals in biological systems: a review orientated to inflammatory processes
    • Blake D.R. Allen R.E. Lunec J. Free radicals in biological systems: a review orientated to inflammatory processes Br Med Bull 43 1987 371 385
    • (1987) Br Med Bull , vol.43 , pp. 371-385
    • Blake, D.R.1    Allen, R.E.2    Lunec, J.3
  • 35
    • 0023928493 scopus 로고
    • Binding of haptoglobin, inter-alpha-trypsin inhibitor, and alpha-l-proteinase inhibitor to synovial fluid hyaluronate and the influence of these proteins on its degradation by oxygen derived free radicals
    • Hutadilok N. Ghosh P. Brooks P.M. Binding of haptoglobin, inter-alpha-trypsin inhibitor, and alpha-l-proteinase inhibitor to synovial fluid hyaluronate and the influence of these proteins on its degradation by oxygen derived free radicals Ann Rheum Dis 47 1988 377 385
    • (1988) Ann Rheum Dis , vol.47 , pp. 377-385
    • Hutadilok, N.1    Ghosh, P.2    Brooks, P.M.3
  • 36
    • 0024405599 scopus 로고
    • Plasma proteins in synovial fluids of normal human joints
    • Weinberger A. Simkin P.A. Plasma proteins in synovial fluids of normal human joints Semin Arthritis Rheum 19 1989 66 76
    • (1989) Semin Arthritis Rheum , vol.19 , pp. 66-76
    • Weinberger, A.1    Simkin, P.A.2
  • 38
    • 0027371286 scopus 로고
    • NSAIDs in the treatment of osteoarthritis: friends or foes
    • Brandt K.D. NSAIDs in the treatment of osteoarthritis: friends or foes Bull Rheum Dis 42 1993 1 4
    • (1993) Bull Rheum Dis , vol.42 , pp. 1-4
    • Brandt, K.D.1
  • 39
    • 0027526417 scopus 로고
    • Should nonsteroidal antiinflammatory drugs be used to treat osteoarthritis
    • Brandt K.D. Should nonsteroidal antiinflammatory drugs be used to treat osteoarthritis Rheum Dis Clin North Am 19 1993 29 44
    • (1993) Rheum Dis Clin North Am , vol.19 , pp. 29-44
    • Brandt, K.D.1
  • 40
    • 0022999275 scopus 로고
    • Nonsteroidal antiinflammatory drugs in treatment of osteoarthritis
    • Brandt K.D. Slowman-Kovacs S. Nonsteroidal antiinflammatory drugs in treatment of osteoarthritis Clin Orthop 213 1986 84 91
    • (1986) Clin Orthop , vol.213 , pp. 84-91
    • Brandt, K.D.1    Slowman-Kovacs, S.2
  • 41
    • 0026732067 scopus 로고
    • Trends in the utilization of non-steroidal anti-inflammatory drugs in the United States, 1986–1990
    • Gabriel S.E. Fehring R.A. Trends in the utilization of non-steroidal anti-inflammatory drugs in the United States, 1986–1990 J Clin Epidemiol 45 1992 1041 1044
    • (1992) J Clin Epidemiol , vol.45 , pp. 1041-1044
    • Gabriel, S.E.1    Fehring, R.A.2
  • 42
    • 84988223659 scopus 로고    scopus 로고
    • Costs and effectiveness of nonsteroidal anti-inflammatory drugs: the importance of reducing side effects
    • Gabriel S.E. Wagner J.L. Costs and effectiveness of nonsteroidal anti-inflammatory drugs: the importance of reducing side effects Arthritis Care Res 10 1997 56 63
    • (1997) Arthritis Care Res , vol.10 , pp. 56-63
    • Gabriel, S.E.1    Wagner, J.L.2
  • 43
    • 0027181491 scopus 로고
    • A two year, placebo-controlled trial of non-steroidal anti-inflammatory therapy in osteoarthritis of the knee joint
    • Dieppe P. Cushnaghan J. Jasani M.K. McCrae F. Watt I. A two year, placebo-controlled trial of non-steroidal anti-inflammatory therapy in osteoarthritis of the knee joint Br J Rheumatol 32 1993 595 600
    • (1993) Br J Rheumatol , vol.32 , pp. 595-600
    • Dieppe, P.1    Cushnaghan, J.2    Jasani, M.K.3    McCrae, F.4    Watt, I.5
  • 44
    • 0025998097 scopus 로고
    • Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs: a meta-analysis
    • Gabriel S.E. Jaakkimainen L. Bombardier C. Risk for serious gastrointestinal complications related to use of nonsteroidal anti-inflammatory drugs: a meta-analysis Ann Intern Med 115 1991 787 796
    • (1991) Ann Intern Med , vol.115 , pp. 787-796
    • Gabriel, S.E.1    Jaakkimainen, L.2    Bombardier, C.3
  • 45
    • 0028795025 scopus 로고
    • Nonsteroidal antiinflammatory drugs and the gastrointestinal tract: the doubleedged sword
    • Lichtenstein D.R. Syngal S. Wolfe M.M. Nonsteroidal antiinflammatory drugs and the gastrointestinal tract: the doubleedged sword Arthritis Rheum 38 1995 5 18
    • (1995) Arthritis Rheum , vol.38 , pp. 5-18
    • Lichtenstein, D.R.1    Syngal, S.2    Wolfe, M.M.3
  • 46
    • 0031053145 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug-induced gastrointestinal toxicity: new insights into an old problem
    • Davies M.N. Wallace J.L. Nonsteroidal anti-inflammatory drug-induced gastrointestinal toxicity: new insights into an old problem J Gastroenterol 32 1997 127 133
    • (1997) J Gastroenterol , vol.32 , pp. 127-133
    • Davies, M.N.1    Wallace, J.L.2
  • 48
    • 0029990706 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug-induced hepatic disorders: incidence and prevention
    • Manoukian A.V. Carson J.L. Nonsteroidal anti-inflammatory drug-induced hepatic disorders: incidence and prevention Drug Safety 15 1996 64 71
    • (1996) Drug Safety , vol.15 , pp. 64-71
    • Manoukian, A.V.1    Carson, J.L.2
  • 49
    • 0028838390 scopus 로고
    • Effects of anti-inflammatory drugs on the progression of osteoarthritis of the knee
    • Huskisson E.C. Berry H. Gishen P. Jubb R.W. Whitehead J. Effects of anti-inflammatory drugs on the progression of osteoarthritis of the knee J Rheumatol 22 1995 1941 1946
    • (1995) J Rheumatol , vol.22 , pp. 1941-1946
    • Huskisson, E.C.1    Berry, H.2    Gishen, P.3    Jubb, R.W.4    Whitehead, J.5
  • 50
    • 0025005862 scopus 로고
    • The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
    • Fu J.Y. Musferrer J.L. Seibert K. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes J Biol Chem 265 1990 16737 16740
    • (1990) J Biol Chem , vol.265 , pp. 16737-16740
    • Fu, J.Y.1    Musferrer, J.L.2    Seibert, K.3
  • 51
    • 0003049413 scopus 로고
    • Relative potency of non-steroid antiinflammatory drugs as inhibitors of cycloxygenase-1 and cycloxygenase-2
    • Akarasereenont P. Mitchell J.A. Thiemermann C. Vane J.R. Relative potency of non-steroid antiinflammatory drugs as inhibitors of cycloxygenase-1 and cycloxygenase-2 Br J Pharmacol 112 1994 183
    • (1994) Br J Pharmacol , vol.112 , pp. 183
    • Akarasereenont, P.1    Mitchell, J.A.2    Thiemermann, C.3    Vane, J.R.4
  • 52
    • 0026744831 scopus 로고
    • Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide sythase induced by human chorionic gonadotropin ingranulosa cells of rat preovulatory follicles
    • Sirios J. Richards J.S. Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide sythase induced by human chorionic gonadotropin ingranulosa cells of rat preovulatory follicles J Biol Chem 267 1992 6382 6388
    • (1992) J Biol Chem , vol.267 , pp. 6382-6388
    • Sirios, J.1    Richards, J.S.2
  • 53
    • 0029928405 scopus 로고    scopus 로고
    • Mechanism of action of anti-inflammatory drugs
    • Vane J.R. Botting R.M. Mechanism of action of anti-inflammatory drugs Scand J Rheumatol 25 1996 9 21
    • (1996) Scand J Rheumatol , vol.25 , pp. 9-21
    • Vane, J.R.1    Botting, R.M.2
  • 54
    • 0027480087 scopus 로고
    • Differential inhibition of prostaglandin endoperoxidase synthase (cyclooxygenase) isoenzymes by aspirin and other non-steroidal antiinflammatory drugs
    • Meade E.A. Smith W.L. DeWitt D.L. Differential inhibition of prostaglandin endoperoxidase synthase (cyclooxygenase) isoenzymes by aspirin and other non-steroidal antiinflammatory drugs J Biol Chem 268 1993 6610 6614
    • (1993) J Biol Chem , vol.268 , pp. 6610-6614
    • Meade, E.A.1    Smith, W.L.2    DeWitt, D.L.3
  • 55
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchell J.A. Akarasereenont P. Thiemermann C. Flower R.J. Vane J.R. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase Proc Natl Acad Sci USA 90 1993 1693 1697
    • (1993) , pp. 1693-1697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemermann, C.3    Flower, R.J.4    Vane, J.R.5
  • 56
    • 0029867761 scopus 로고    scopus 로고
    • Pharmacology of meloxicam, a new non-steroidal anti-inflammatory drug with an improved safety profile through preferential inhibition of COX-2
    • Engelhardt G. Pharmacology of meloxicam, a new non-steroidal anti-inflammatory drug with an improved safety profile through preferential inhibition of COX-2 Br J Rheumatol 35 1996 4 12
    • (1996) Br J Rheumatol , vol.35 , pp. 4-12
    • Engelhardt, G.1
  • 58
    • 0028860983 scopus 로고
    • Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance
    • Engelhardt G. Homma D. Schlegel K. Utzmann R. Schnitzler C. Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance Inflamm Res 44 1995 423 433
    • (1995) Inflamm Res , vol.44 , pp. 423-433
    • Engelhardt, G.1    Homma, D.2    Schlegel, K.3    Utzmann, R.4    Schnitzler, C.5
  • 61
    • 0022973486 scopus 로고
    • Prostaglandins posthanscriptionally inhibit monocyte expression of interleukin-1 activity by increasing intracellular cyclic adenosine monophosphate
    • Knudsen P.J. Dinarello C.A. Strom T.B. Prostaglandins posthanscriptionally inhibit monocyte expression of interleukin-1 activity by increasing intracellular cyclic adenosine monophosphate J Immunol 137 1986 3189 3194
    • (1986) J Immunol , vol.137 , pp. 3189-3194
    • Knudsen, P.J.1    Dinarello, C.A.2    Strom, T.B.3
  • 63
    • 0030583393 scopus 로고    scopus 로고
    • Prostaglandin E2 stimulates incorporation of proline into collagenase digestible proteins in human articular chondrocytes: identification of aneffector autocrine loop involving insulin-like growth factor 1
    • 2 stimulates incorporation of proline into collagenase digestible proteins in human articular chondrocytes: identification of aneffector autocrine loop involving insulin-like growth factor 1 Mol Cell Endocrinol 123 1996 27 35
    • (1996) Mol Cell Endocrinol , vol.123 , pp. 27-35
    • Di Battista, J.A.1    Doré, S.2    Martel-Pelletier, J.3    Pelletier, J-P.4
  • 64
    • 0031051917 scopus 로고    scopus 로고
    • Effects of meloxicam compared to acetylsalicyclic acid in human articular chondrocytes
    • Bassleer C. Magotteaux J. Geenen V. Malaise M. Effects of meloxicam compared to acetylsalicyclic acid in human articular chondrocytes Pharmacology 54 1997 49 56
    • (1997) Pharmacology , vol.54 , pp. 49-56
    • Bassleer, C.1    Magotteaux, J.2    Geenen, V.3    Malaise, M.4
  • 65
    • 85119792724 scopus 로고    scopus 로고
    • Dingle JT. The effect of NSAID on human articularcartilage. Glycosaminoglycan synthesis. Osteoarthritis Cart (in press).
  • 66
    • 0030977129 scopus 로고    scopus 로고
    • Chondroneutrality of meloxicam in rats with spontaneous ostenarthosis of the ankle joint
    • Mohr W. Lehmann H. Engelhardt G. Chondroneutrality of meloxicam in rats with spontaneous ostenarthosis of the ankle joint Z Rheumatol 56 1997 21 30
    • (1997) Z Rheumatol , vol.56 , pp. 21-30
    • Mohr, W.1    Lehmann, H.2    Engelhardt, G.3
  • 67
    • 0027364715 scopus 로고
    • Nonsteroidal anti-inflammatory drugs and chondroprotection: a review of the evidence
    • Ghosh P. Nonsteroidal anti-inflammatory drugs and chondroprotection: a review of the evidence Drugs 46 1993 834 846
    • (1993) Drugs , vol.46 , pp. 834-846
    • Ghosh, P.1
  • 68
    • 0026588518 scopus 로고
    • Effects of tiaprofenic acid (Surgam) on cartilage proteoglycans in the rabbit joint immobilisation model
    • Meyer-Carrive I. Ghosh P. Effects of tiaprofenic acid (Surgam) on cartilage proteoglycans in the rabbit joint immobilisation model Ann Rheum Dis 51 1992 448 455
    • (1992) Ann Rheum Dis , vol.51 , pp. 448-455
    • Meyer-Carrive, I.1    Ghosh, P.2
  • 69
    • 0025851681 scopus 로고
    • Cartilage maintenance in osteoarthritis: interaction of cytokines, NSAID and prostaglandins in articular cartilage damage and repair
    • Dingle J.T. Cartilage maintenance in osteoarthritis: interaction of cytokines, NSAID and prostaglandins in articular cartilage damage and repair J Rheumatol 18 1991 30 37
    • (1991) J Rheumatol , vol.18 , pp. 30-37
    • Dingle, J.T.1
  • 70
    • 0022913407 scopus 로고
    • Laboratory evaluation of glycosaminoglycan polysulphate ester for chondroprotective activity
    • Burkhardt D. Ghosh P. Laboratory evaluation of glycosaminoglycan polysulphate ester for chondroprotective activity Curr Ther Res 40 1986 1034 1053
    • (1986) Curr Ther Res , vol.40 , pp. 1034-1053
    • Burkhardt, D.1    Ghosh, P.2
  • 71
    • 0024265476 scopus 로고
    • Anti-rheumatic drugs and cartilage
    • Ghosh P. Anti-rheumatic drugs and cartilage Brooks P.M. Bailliere's clinical rheumatology international practice and research 1988 Bailliere Tindall London 309 338
    • (1988) , pp. 309-338
    • Ghosh, P.1
  • 72
    • 0005069896 scopus 로고
    • Second line agents in osteoarthritis
    • Ghosh P. Smith M. Wells C. Second line agents in osteoarthritis Dixon J.S. Furst D.E. Second Line Agents in the Treatment of Rheumatic Diseases 1992 Dekker New York 363 427
    • (1992) , pp. 363-427
    • Ghosh, P.1    Smith, M.2    Wells, C.3
  • 74
    • 0000345891 scopus 로고
    • Disease-modifying antirheumatic drugs: current status of their application in animal models of osteoarthritis
    • Howell D.S. Altman R.D. Pelletier J-P. Martel-Pelletier J. Dean D.D. Disease-modifying antirheumatic drugs: current status of their application in animal models of osteoarthritis Kuettner K. Goldberg V. Osteoarthritis Disorders Am Acad Orthop Surg 1995 365 377
    • (1995) , pp. 365-377
    • Howell, D.S.1    Altman, R.D.2    Pelletier, J-P.3    Martel-Pelletier, J.4    Dean, D.D.5
  • 75
    • 0029857984 scopus 로고    scopus 로고
    • Design and conduct of clinical trials in patients with osteoarthritis: recommendations from a task force of the Osteoarthritis Research Society
    • Altman R. Brandt K. Hochberg M. Moskowitz R. Bellamy N. Bloch D.A. Design and conduct of clinical trials in patients with osteoarthritis: recommendations from a task force of the Osteoarthritis Research Society Osteoarthritis Cart 4 1996 217 243
    • (1996) Osteoarthritis Cart , vol.4 , pp. 217-243
    • Altman, R.1    Brandt, K.2    Hochberg, M.3    Moskowitz, R.4    Bellamy, N.5    Bloch, D.A.6
  • 76
    • 0023522786 scopus 로고
    • Preferential localization of 3H-pentosanpolysulphate to the urinary tract in rats
    • Odlind B. Dencker L. Tengblad A. Preferential localization of 3H-pentosanpolysulphate to the urinary tract in rats Pharmacol Toxicol 61 1987 162 166
    • (1987) Pharmacol Toxicol , vol.61 , pp. 162-166
    • Odlind, B.1    Dencker, L.2    Tengblad, A.3
  • 77
    • 0343246844 scopus 로고
    • Pentosan polysulphate (Elmiron): pharmacokinetics and effects of the urinary inhibition of crystal growth
    • Fellström B. Björklund U. Danielson B.G. Eriksson H. Odlind B. Tengblad A. Pentosan polysulphate (Elmiron): pharmacokinetics and effects of the urinary inhibition of crystal growth Proceedings of the Harnstein-Symposum March 2022 Bonn 1986 340 344
    • (1986) , pp. 340-344
    • Fellström, B.1    Björklund, U.2    Danielson, B.G.3    Eriksson, H.4    Odlind, B.5    Tengblad, A.6
  • 78
    • 0025833457 scopus 로고
    • Profibrinolytic and anticoagulant properties of the pentosan polysulphate derivative bego 0391
    • Klöcking H-P. Hauptmann J. Richter M. Profibrinolytic and anticoagulant properties of the pentosan polysulphate derivative bego 0391 Pharmazie 46 1991 543 544
    • (1991) Pharmazie , vol.46 , pp. 543-544
    • Klöcking, H-P.1    Hauptmann, J.2    Richter, M.3
  • 79
    • 0026770001 scopus 로고
    • Ageing and t-PA relase by calcium and sodium pentosan polysulphate after oral application in rats
    • Klöcking H-P. Ageing and t-PA relase by calcium and sodium pentosan polysulphate after oral application in rats Fibrinolysis 6 1992 42 43
    • (1992) Fibrinolysis , vol.6 , pp. 42-43
    • Klöcking, H-P.1
  • 80
    • 85119804878 scopus 로고
    • A comparative study of the anti-thrombotic effects of calcium and sodium xylopyranose polysulphate in a rat injury model using subcutaneous andoral routes of administration
    • (personal communication from Dr M Scholz; Benechemie, Munich) Breddin H.K. Geidrojc J. A comparative study of the anti-thrombotic effects of calcium and sodium xylopyranose polysulphate in a rat injury model using subcutaneous andoral routes of administration 1994
    • (1994)
    • Breddin, H.K.1    Geidrojc, J.2
  • 81
    • 85119814974 scopus 로고
    • Calcium pentosan polysulphate (CaPPS) stimulates release of superoxide dismutase (SOD) from endothelium in vitro and in vivo
    • Bowman L. Jackson C. Smith M.M. Ghosh P. Calcium pentosan polysulphate (CaPPS) stimulates release of superoxide dismutase (SOD) from endothelium in vitro and in vivo 7th Biennial Scientific Meeting of the International Society for Free Radical Research November 6–10, 1994 NWS Sydney
    • (1994)
    • Bowman, L.1    Jackson, C.2    Smith, M.M.3    Ghosh, P.4
  • 82
    • 85119817155 scopus 로고    scopus 로고
    • Laboratory and clinical studies on calcium pentosan polysulphate
    • Verbruggen G. Veys E.M. Laboratory and clinical studies on calcium pentosan polysulphate Osteoarthritis Cart 4 1996 iii iv
    • (1996) Osteoarthritis Cart , vol.4 , pp. iii-iv
    • Verbruggen, G.1    Veys, E.M.2
  • 83
    • 0022716017 scopus 로고
    • Characterization of xylansulfate by size exclusion chromatography
    • Jacobsson O. Kiiver T. Granath K. Characterization of xylansulfate by size exclusion chromatography J Liquid Chromatogr 9 1986 1549 1561
    • (1986) J Liquid Chromatogr , vol.9 , pp. 1549-1561
    • Jacobsson, O.1    Kiiver, T.2    Granath, K.3
  • 84
    • 0027312236 scopus 로고
    • Determination of the average molecular size of glycosaminoglycans by fast protein liquid chromatography
    • Melrose J. Ghosh P. Determination of the average molecular size of glycosaminoglycans by fast protein liquid chromatography J Chromatogr 637 1993 91 95
    • (1993) J Chromatogr , vol.637 , pp. 91-95
    • Melrose, J.1    Ghosh, P.2
  • 85
    • 0026536919 scopus 로고
    • Cartilage and diarthrodial joints as paradigms for hierarchical materials and structures
    • Mow V.C. Ratcliffe A. Poole A.R. Cartilage and diarthrodial joints as paradigms for hierarchical materials and structures Biomaterials 13 1992 67 97
    • (1992) Biomaterials , vol.13 , pp. 67-97
    • Mow, V.C.1    Ratcliffe, A.2    Poole, A.R.3
  • 86
    • 0006286783 scopus 로고
    • Biological functions of dermatan sulphate proteoglycans
    • Rosenberg L. Tang L.H. Choi H.U. Johnson T. Biological functions of dermatan sulphate proteoglycans Scott J.E. Dermatan sulphate proteoglycans: chemistry, biology, chemical pathology 1993 Portland Press London 225 239
    • (1993) , pp. 225-239
    • Rosenberg, L.1    Tang, L.H.2    Choi, H.U.3    Johnson, T.4
  • 87
    • 0021362952 scopus 로고
    • The periphery of the developing collagen fibril: quantitative relationship with dermatan sulphate and other surface-associated species
    • Scott J.E. The periphery of the developing collagen fibril: quantitative relationship with dermatan sulphate and other surface-associated species Biochem J 218 1984 229 233
    • (1984) Biochem J , vol.218 , pp. 229-233
    • Scott, J.E.1
  • 88
    • 0023581851 scopus 로고
    • Fibronectin-mediated adhesion of fibroblasts: inhibition by dermatan sulfate proteoglycan and evidence for a cryptic glycosaminoglycan-binding domain
    • Lewandowska K. Choi H.U. Rosenberg L.C. Zardi L. Culp L.A. Fibronectin-mediated adhesion of fibroblasts: inhibition by dermatan sulfate proteoglycan and evidence for a cryptic glycosaminoglycan-binding domain J Cell Biol 105 1987 1443 1454
    • (1987) J Cell Biol , vol.105 , pp. 1443-1454
    • Lewandowska, K.1    Choi, H.U.2    Rosenberg, L.C.3    Zardi, L.4    Culp, L.A.5
  • 90
    • 0021715115 scopus 로고
    • Specific inhibition of type 1 and type 2 collagen fibrillogenesis by the proteoglycan of tendon
    • Vogel K.G. Paulsson M. Heinegåxd D. Specific inhibition of type 1 and type 2 collagen fibrillogenesis by the proteoglycan of tendon Biochem J 223 1984 587 597
    • (1984) Biochem J , vol.223 , pp. 587-597
    • Vogel, K.G.1    Paulsson, M.2    Heinegåxd, D.3
  • 91
    • 0023645618 scopus 로고
    • Proteoglycans of fetal bovine tendon
    • Vogel K.G. Evanko S.P. Proteoglycans of fetal bovine tendon J Biol Chem 262 1987 13607 13613
    • (1987) J Biol Chem , vol.262 , pp. 13607-13613
    • Vogel, K.G.1    Evanko, S.P.2
  • 92
    • 0027948072 scopus 로고
    • The effects of loading on the synthesis of biglycan and decorin in intact mature articular cartilage in vitro
    • Visser N.A. Vankampen G.P. Dekoning M.H. Vanderkorst J.K. The effects of loading on the synthesis of biglycan and decorin in intact mature articular cartilage in vitro Connect Tissue Res 30 1994 241 250
    • (1994) Connect Tissue Res , vol.30 , pp. 241-250
    • Visser, N.A.1    Vankampen, G.P.2    Dekoning, M.H.3    Vanderkorst, J.K.4
  • 93
    • 0030152832 scopus 로고    scopus 로고
    • Topographic variation in biglycan and decorin synthesis by articular cartilage in the early stages of osteoarthritis: an experimental study in sheep
    • Little C.B. Ghosh P. Bellenger C.R. Topographic variation in biglycan and decorin synthesis by articular cartilage in the early stages of osteoarthritis: an experimental study in sheep J Orthop Res 14 1996 433 444
    • (1996) J Orthop Res , vol.14 , pp. 433-444
    • Little, C.B.1    Ghosh, P.2    Bellenger, C.R.3
  • 94
    • 0026091412 scopus 로고
    • Joint destruction in arthritis: metalloproteinases in the spotlight
    • Brinckerhoff C.E. Joint destruction in arthritis: metalloproteinases in the spotlight Arthritis Rheum 34 1991 1073 1075
    • (1991) Arthritis Rheum , vol.34 , pp. 1073-1075
    • Brinckerhoff, C.E.1
  • 95
    • 0015597248 scopus 로고
    • Degradation of proteoglycans in human osteoarthritic cartilage
    • Altman R.D. Pita J.C. Howell D.S. Degradation of proteoglycans in human osteoarthritic cartilage Arthritis Rheum 16 1973 179 185
    • (1973) Arthritis Rheum , vol.16 , pp. 179-185
    • Altman, R.D.1    Pita, J.C.2    Howell, D.S.3
  • 96
    • 0028247201 scopus 로고
    • Excess of metalloproteases over fissue inhibitor of metalloprotease may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis
    • Martel-Pelletier J. McCollum R. Fujimoto N. Obata K. Cloutier J-M. Pelletier J-P. Excess of metalloproteases over fissue inhibitor of metalloprotease may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis Lab Invest 70 1994 807 815
    • (1994) Lab Invest , vol.70 , pp. 807-815
    • Martel-Pelletier, J.1    McCollum, R.2    Fujimoto, N.3    Obata, K.4    Cloutier, J-M.5    Pelletier, J-P.6
  • 97
    • 0026736030 scopus 로고
    • Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium
    • Okada Y. Shinmei M. Tanaka O. Naka K. Kimura A. Nakanishi I. Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium Lab Invest 66 1992 680 690
    • (1992) Lab Invest , vol.66 , pp. 680-690
    • Okada, Y.1    Shinmei, M.2    Tanaka, O.3    Naka, K.4    Kimura, A.5    Nakanishi, I.6
  • 98
    • 0031978254 scopus 로고    scopus 로고
    • Matrix metalloproteinases and TIMPs: properties and implications for the rheumatic diseases
    • March Cawston T. Matrix metalloproteinases and TIMPs: properties and implications for the rheumatic diseases Mol Med Today 1998 130 137
    • (1998) Mol Med Today , pp. 130-137
    • Cawston, T.1
  • 99
    • 0026052818 scopus 로고
    • Metalloproteinase digestion of cartilage proteoglycan: pattern of cleavage by stromelysin and susceptibility to collagenase
    • Hughes C. Murphy G. Hardingham T.E. Metalloproteinase digestion of cartilage proteoglycan: pattern of cleavage by stromelysin and susceptibility to collagenase Biochem J 279 1991 733 739
    • (1991) Biochem J , vol.279 , pp. 733-739
    • Hughes, C.1    Murphy, G.2    Hardingham, T.E.3
  • 101
    • 0026504563 scopus 로고
    • Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan: evidence for proteolysis at this site in vivo inhuman articular cartilage
    • Flannery C.R. Lark M.W. Sandy J.D. Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan: evidence for proteolysis at this site in vivo inhuman articular cartilage J Biol Chem 267 1992 1008 1014
    • (1992) J Biol Chem , vol.267 , pp. 1008-1014
    • Flannery, C.R.1    Lark, M.W.2    Sandy, J.D.3
  • 102
    • 0029852094 scopus 로고    scopus 로고
    • Aggrecan is degraded by matrix metalloproteinases in human arthritis: evidence that matrix metalloproteinase and aggrecanase activities can be independent
    • Fosang A.J. Last K. Maciewicz R.A. Aggrecan is degraded by matrix metalloproteinases in human arthritis: evidence that matrix metalloproteinase and aggrecanase activities can be independent J Clin Invest 98 1996 2292 2299
    • (1996) J Clin Invest , vol.98 , pp. 2292-2299
    • Fosang, A.J.1    Last, K.2    Maciewicz, R.A.3
  • 103
    • 0028919163 scopus 로고
    • Monoclonal antibodies that specifically recognize neoepitope sequences generated by aggrecanase and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro
    • Hughes C.E. Caterson B. Fosang A.J. Roughley P.J. Mort J.S. Monoclonal antibodies that specifically recognize neoepitope sequences generated by aggrecanase and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro Biochem J 305 1995 799 804
    • (1995) Biochem J , vol.305 , pp. 799-804
    • Hughes, C.E.1    Caterson, B.2    Fosang, A.J.3    Roughley, P.J.4    Mort, J.S.5
  • 104
    • 0028871942 scopus 로고
    • Use of an antibody against the matrix metalloproteinase-generated aggrecan nenepitope FVDIPEN-COOH to assess the effects of stromelysin in a rabbitmodel of cartilage degradation
    • Bayne E.K. MacNaul K.L. Donatelli S.A. Christen A. Griffin P.R. Hoermer L.A. Use of an antibody against the matrix metalloproteinase-generated aggrecan nenepitope FVDIPEN-COOH to assess the effects of stromelysin in a rabbitmodel of cartilage degradation Arthritis Rheum 38 1995 1400 1409
    • (1995) Arthritis Rheum , vol.38 , pp. 1400-1409
    • Bayne, E.K.1    MacNaul, K.L.2    Donatelli, S.A.3    Christen, A.4    Griffin, P.R.5    Hoermer, L.A.6
  • 105
    • 0026682509 scopus 로고
    • The structure of aggrecan fragments in human synovial fluid: evidence for the involvement in osteoarthrits of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain
    • Sandy J.D. Flannery C.R. Neame P.J. Lohmander L.S. The structure of aggrecan fragments in human synovial fluid: evidence for the involvement in osteoarthrits of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain J Clin Invest 89 1992 1512 1516
    • (1992) J Clin Invest , vol.89 , pp. 1512-1516
    • Sandy, J.D.1    Flannery, C.R.2    Neame, P.J.3    Lohmander, L.S.4
  • 106
    • 0027445981 scopus 로고
    • The structure of aggrecan fragments in human synovial fluid: evidence that aggrecanase mediates cartilage degradation in inflammatory jointdisease, joint injury, and osteoarthritis
    • Lohmander L.S. Neame P.J. Sandy J.D. The structure of aggrecan fragments in human synovial fluid: evidence that aggrecanase mediates cartilage degradation in inflammatory jointdisease, joint injury, and osteoarthritis Arthritis Rheum 36 1993 1214 1222
    • (1993) Arthritis Rheum , vol.36 , pp. 1214-1222
    • Lohmander, L.S.1    Neame, P.J.2    Sandy, J.D.3
  • 107
    • 0027438713 scopus 로고
    • Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin-B and an inhibitor of matrix metalloproteinases: evidence fortwo converging pathways of chondrocyte-mediated proteoglycan degradation
    • Buttle D.J. Handley C.J. Ilic M.Z. Saklatvatvala J. Murata M. Barrett A.J. Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin-B and an inhibitor of matrix metalloproteinases: evidence fortwo converging pathways of chondrocyte-mediated proteoglycan degradation Arthritis Rheum 36 1993 1709 1717
    • (1993) Arthritis Rheum , vol.36 , pp. 1709-1717
    • Buttle, D.J.1    Handley, C.J.2    Ilic, M.Z.3    Saklatvatvala, J.4    Murata, M.5    Barrett, A.J.6
  • 109
    • 85119818284 scopus 로고    scopus 로고
    • The interglobular domain of cartilage aggrecan is cleaved by hemorrhagic metalloproteinase HT-D (atrolysin C) at the matrix metalloproteinase andaggrecanase sites
    • Tortorella M.D. Pratta M.A. Fox J.W. Arner E.C. The interglobular domain of cartilage aggrecan is cleaved by hemorrhagic metalloproteinase HT-D (atrolysin C) at the matrix metalloproteinase andaggrecanase sites Trans Orthop Res 23 1998 81
    • (1998) Trans Orthop Res , vol.23 , pp. 81
    • Tortorella, M.D.1    Pratta, M.A.2    Fox, J.W.3    Arner, E.C.4
  • 111
    • 0010445896 scopus 로고    scopus 로고
    • The catalytic domain of membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan IGD substrate (raggimut) at the‘aggrecanase’-site
    • Büttner F.H. Hughes C.E. Margerie D. Lichte A. Tschesche H. Caterson B. The catalytic domain of membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan IGD substrate (raggimut) at the‘aggrecanase’-site Trans Orthop Res Soc 23 1998 84
    • (1998) Trans Orthop Res Soc , vol.23 , pp. 84
    • Büttner, F.H.1    Hughes, C.E.2    Margerie, D.3    Lichte, A.4    Tschesche, H.5    Caterson, B.6
  • 112
    • 0002711588 scopus 로고
    • Biochemically induced osteoarthritis in the chicken and rat
    • Kalbhen D.A. Biochemically induced osteoarthritis in the chicken and rat Munthe E. Bjelle A Effects of drugs on osteoarthritis 1984 Hans Huber, Berne, Stuttgart, Vienna 48 68
    • (1984) , pp. 48-68
    • Kalbhen, D.A.1
  • 113
    • 0022509087 scopus 로고
    • Polysulphated polysaccharides: an in vitro study of their effects on proteoglycan biosynthesis by articular chondrocytes
    • Costeseque R. Emonds-Alt X. Breliere J.C. Roncucci R. Polysulphated polysaccharides: an in vitro study of their effects on proteoglycan biosynthesis by articular chondrocytes Arch Int Pharmacodyn Ther 282 1986 196 208
    • (1986) Arch Int Pharmacodyn Ther , vol.282 , pp. 196-208
    • Costeseque, R.1    Emonds-Alt, X.2    Breliere, J.C.3    Roncucci, R.4
  • 114
    • 0024477225 scopus 로고
    • Evaluation of the effects of antiarthritic drugs on the secretion of proteoglycans by lapine chondrocytes using a novel assay procedure
    • Collier S. Ghosh P. Evaluation of the effects of antiarthritic drugs on the secretion of proteoglycans by lapine chondrocytes using a novel assay procedure Ann Rheum Dis 48 1989 372 381
    • (1989) Ann Rheum Dis , vol.48 , pp. 372-381
    • Collier, S.1    Ghosh, P.2
  • 115
    • 0030899324 scopus 로고    scopus 로고
    • Effects of pentosan polysulfate on peripheral blood leukocyte populations and mononuclear cell procoagulant activity in patients withosteoarthritis
    • Anderson J.M. Edelman J. Ghosh P. Effects of pentosan polysulfate on peripheral blood leukocyte populations and mononuclear cell procoagulant activity in patients withosteoarthritis Curr Ther Res 58 1997 93 107
    • (1997) Curr Ther Res , vol.58 , pp. 93-107
    • Anderson, J.M.1    Edelman, J.2    Ghosh, P.3
  • 117
    • 85119788532 scopus 로고    scopus 로고
    • The dose-dependent effects of calcium xylopyranose polysulphate on the metabolism of ovine articular chondrocytes
    • Smith M.M. Ghosh P. The dose-dependent effects of calcium xylopyranose polysulphate on the metabolism of ovine articular chondrocytes Proceedings of the Matrix Biology Society of Australia and New Zealand 1 1997 S8
    • (1997) , pp. S8
    • Smith, M.M.1    Ghosh, P.2
  • 118
    • 0024199333 scopus 로고
    • Differences between subpopulations of cultured bovine articular chondrocytes: morphology and cartilage matrix production
    • Aydelotte M.B. Kuettner K.E. Differences between subpopulations of cultured bovine articular chondrocytes: morphology and cartilage matrix production Connect Tissue Res 18 1988 205 222
    • (1988) Connect Tissue Res , vol.18 , pp. 205-222
    • Aydelotte, M.B.1    Kuettner, K.E.2
  • 120
    • 0028302391 scopus 로고
    • Cartilage proteoglycans: structure and potential functions
    • Roughley P.J. Lee E.R. Cartilage proteoglycans: structure and potential functions Microsc Res 28 1994 385 397
    • (1994) Microsc Res , vol.28 , pp. 385-397
    • Roughley, P.J.1    Lee, E.R.2
  • 122
    • 85119805325 scopus 로고    scopus 로고
    • Polysulfated polysaccharides increase the molecular size of aggrecan aggregates synthesized by human chondrocytes cultured in gelified agarose
    • Verbruggen G. Cornelissen M. Broddelez C. Veys E.M. Polysulfated polysaccharides increase the molecular size of aggrecan aggregates synthesized by human chondrocytes cultured in gelified agarose Osteoarthritis Cartilage 5 1997 61
    • (1997) Osteoarthritis Cartilage , vol.5 , pp. 61
    • Verbruggen, G.1    Cornelissen, M.2    Broddelez, C.3    Veys, E.M.4
  • 123
    • 0027316964 scopus 로고
    • Expression of 92-KD type-IV collagenase gelatinase (gelatinase-B) in osteoarthrrtic cartilage and its induction in normal human articular cartilageby interleukin-1
    • Mohtai M. Smith R.P. Schurman D.J. Tsuji Y. Torti F.M. Hutchinson N.I. Expression of 92-KD type-IV collagenase gelatinase (gelatinase-B) in osteoarthrrtic cartilage and its induction in normal human articular cartilageby interleukin-1 J Clin Invest 92 1993 179 185
    • (1993) J Clin Invest , vol.92 , pp. 179-185
    • Mohtai, M.1    Smith, R.P.2    Schurman, D.J.3    Tsuji, Y.4    Torti, F.M.5    Hutchinson, N.I.6
  • 124
    • 0028328915 scopus 로고
    • Increased damage to type II collagen in osteoarthrrtic articular cartilage detected by a new immunoassay
    • Hollander A.P. Heathfield T.F. Webber C. Iwata Y. Bourne R. Rorabeck C. Increased damage to type II collagen in osteoarthrrtic articular cartilage detected by a new immunoassay J Clin Invest 93 1994 1722 1732
    • (1994) J Clin Invest , vol.93 , pp. 1722-1732
    • Hollander, A.P.1    Heathfield, T.F.2    Webber, C.3    Iwata, Y.4    Bourne, R.5    Rorabeck, C.6
  • 127
    • 0002365565 scopus 로고
    • Degradation of collagen
    • Werb Z. Degradation of collagen Weiss J.B. Jayson M.I.V. Collagen in health and disease 1982 Churchill Livingston New York 121 134
    • (1982) , pp. 121-134
    • Werb, Z.1
  • 128
    • 84931699765 scopus 로고
    • Capacity of leucocyte elastase and cathepsin G to degrade mature collagen fibers
    • Barrett A.J. Capacity of leucocyte elastase and cathepsin G to degrade mature collagen fibers Havemann K. Janoff A. Neutral proteases of human polymorphonuclear leukocytes: biochemistry, physiology and clinical significance 1978 Urban and Schwarzenberg Baltimore 385 389
    • (1978) , pp. 385-389
    • Barrett, A.J.1
  • 129
    • 0030957218 scopus 로고    scopus 로고
    • Activation mechanisms of matrix metalloproteinases
    • Nagase H. Activation mechanisms of matrix metalloproteinases Biol Chem 378 1997 151 160
    • (1997) Biol Chem , vol.378 , pp. 151-160
    • Nagase, H.1
  • 130
    • 0013829536 scopus 로고
    • Untersuchungen zur Chemie der Arterienwand VIII Nachweis, Reinigung and Eigenschaften der Hyalmonidase aus der Aorta des Rindes
    • Buddecke E. Platt D. Untersuchungen zur Chemie der Arterienwand VIII Nachweis, Reinigung and Eigenschaften der Hyalmonidase aus der Aorta des Rindes Hoppe-Seylers Zeitschrift fur Physiologische Chemie 343 1965 61 79
    • (1965) Hoppe-Seylers Zeitschrift fur Physiologische Chemie , vol.343 , pp. 61-79
    • Buddecke, E.1    Platt, D.2
  • 131
    • 78651196305 scopus 로고
    • Untersuchungen zur Chemie der Arterienwand Reinigung und Eigenschaften der B-Acetylglucosaminidase aus der Aorta des Rindes
    • Buddecke E. Werries E. Untersuchungen zur Chemie der Arterienwand Reinigung und Eigenschaften der B-Acetylglucosaminidase aus der Aorta des Rindes Hoppe-Seylers Zeitschrift fur Physiologische Chemie 340 1965 257 272
    • (1965) Hoppe-Seylers Zeitschrift fur Physiologische Chemie , vol.340 , pp. 257-272
    • Buddecke, E.1    Werries, E.2
  • 132
    • 0023640553 scopus 로고
    • Evidence that sulphated polysaccharides inhibit tumour metastasis by blocking tumour-cell-derived heparinase
    • Parish C.R. Coobe D.R. Jakobsen K.D. Bennett F.A. Underwood P.A. Evidence that sulphated polysaccharides inhibit tumour metastasis by blocking tumour-cell-derived heparinase Int J Cancer 40 1987 511 518
    • (1987) Int J Cancer , vol.40 , pp. 511-518
    • Parish, C.R.1    Coobe, D.R.2    Jakobsen, K.D.3    Bennett, F.A.4    Underwood, P.A.5
  • 133
    • 33646986931 scopus 로고
    • Effect of pentosan polysulphate, standard heparin and related compounds on protein kinase C activity
    • Herbert J-M. Maffrand J-P. Effect of pentosan polysulphate, standard heparin and related compounds on protein kinase C activity Biochim Biophys Acta 109 1991 432 441
    • (1991) Biochim Biophys Acta , vol.109 , pp. 432-441
    • Herbert, J-M.1    Maffrand, J-P.2
  • 134
    • 0025836186 scopus 로고
    • Modulation of interleukin-linduced alterations in cartilage proteoglycan metabolism by activation of protein kinase-C
    • Arner E.C. Pratta M.A. Modulation of interleukin-linduced alterations in cartilage proteoglycan metabolism by activation of protein kinase-C Arthritis Rheum 34 1991 1006 1013
    • (1991) Arthritis Rheum , vol.34 , pp. 1006-1013
    • Arner, E.C.1    Pratta, M.A.2
  • 135
    • 0027753953 scopus 로고
    • Involvement of protein-kinase-C in the interleukin-1 alpha-induced gene expression of matrix metalloproteinases and tissue inhibitor-1 ofmetalloproteinases (TIMP 1) in human uterine cervical fibroblasts
    • Takahashi S. Sato T. Ito A. Ojima Y. Hosono T. Nagase H. Involvement of protein-kinase-C in the interleukin-1 alpha-induced gene expression of matrix metalloproteinases and tissue inhibitor-1 ofmetalloproteinases (TIMP 1) in human uterine cervical fibroblasts Bioc Biop A1220 1993 57 65
    • (1993) Bioc Biop , vol.A1220 , pp. 57-65
    • Takahashi, S.1    Sato, T.2    Ito, A.3    Ojima, Y.4    Hosono, T.5    Nagase, H.6
  • 136
    • 0028297528 scopus 로고
    • Involvement of protein kinase A and C in the production of interleukin-l-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3El
    • 2 from mouse osteoblast-like cell line, MC3T3El Biochim Biophys Acta 1221 1994 78 82
    • (1994) Biochim Biophys Acta , vol.1221 , pp. 78-82
    • Iitaka, M.1    Kitahama, S.2    Ishii, J.3
  • 138
    • 0041705420 scopus 로고    scopus 로고
    • Degradation of bovine nasal cartilage by a neutral protease from human leukocyte granules
    • Kruze D. Salgam P. Fehr K. Boni A. Böni A.0679 0 0679 0 Degradation of bovine nasal cartilage by a neutral protease from human leukocyte granules Willoughby D.A. Giroud T.P. Velo G.P. perspectives in inflammation: future trends and developments Lancaster 1997 MTP Press England 361 370
    • (1997) , pp. 361-370
    • Kruze, D.1    Salgam, P.2    Fehr, K.3    Boni, A.4    Böni, A.0679 0 0679 05
  • 139
    • 0021081481 scopus 로고
    • The interaction of pentosan polysulfate (SP54) with human neutrophil elastase and connective tissue matrix components
    • Andrews J.L. Ghosh P. Lentini A. Temai B. Ternai B.0679 0 0679 0 The interaction of pentosan polysulfate (SP54) with human neutrophil elastase and connective tissue matrix components Chem Biol Interact 47 1983 157 173
    • (1983) Chem Biol Interact , vol.47 , pp. 157-173
    • Andrews, J.L.1    Ghosh, P.2    Lentini, A.3    Temai, B.4    Ternai, B.0679 0 0679 05
  • 140
    • 0019468504 scopus 로고
    • Inhibition of human elastase from polymorphonuclear leucocytes by gold sodium thiomalate and pentosan polysulfate (SP-54®)
    • Baici A. Salgam P. Fehr K. Boni A. Böni A. Inhibition of human elastase from polymorphonuclear leucocytes by gold sodium thiomalate and pentosan polysulfate (SP-54®) Biochem Pharmacol 30 1981 703 708
    • (1981) Biochem Pharmacol , vol.30 , pp. 703-708
    • Baici, A.1    Salgam, P.2    Fehr, K.3    Boni, A.4    Böni, A.5
  • 141
    • 0026060879 scopus 로고
    • Influence of some natural and semisynthetic agents on elastase and cathepsin G from polymorphonuclear granulocytes
    • Steinmeyer J. Kalbhen D.A. Influence of some natural and semisynthetic agents on elastase and cathepsin G from polymorphonuclear granulocytes Arzneimittelforschung 41 1991 77 80
    • (1991) Arzneimittelforschung , vol.41 , pp. 77-80
    • Steinmeyer, J.1    Kalbhen, D.A.2
  • 142
    • 0018715412 scopus 로고
    • Studies on the effect of pentosan polysulfate on proteoglycan degradation by leukocyte neutral proteases
    • Barg W.F. Englert M.E. Buermann C.W. Oronsky A.L. Kerwar S.S. Studies on the effect of pentosan polysulfate on proteoglycan degradation by leukocyte neutral proteases Biochem Pharmacol 28 1979 2639 2643
    • (1979) Biochem Pharmacol , vol.28 , pp. 2639-2643
    • Barg, W.F.1    Englert, M.E.2    Buermann, C.W.3    Oronsky, A.L.4    Kerwar, S.S.5
  • 143
    • 45549112264 scopus 로고
    • The interaction of heparin and SP54 with gelatin
    • Lentini A. Ternai B. Ghosh P. The interaction of heparin and SP54 with gelatin Int J Biol Macromol 10 1988 113 120
    • (1988) Int J Biol Macromol , vol.10 , pp. 113-120
    • Lentini, A.1    Ternai, B.2    Ghosh, P.3
  • 144
    • 78651168254 scopus 로고
    • Vergleichende Untersuchungen der Einwirkung von Heparin and SP54 auf das Farbstoff-Hyaluronidase-Spreading
    • Mathies H. Willms D. Vergleichende Untersuchungen der Einwirkung von Heparin and SP54 auf das Farbstoff-Hyaluronidase-Spreading Med Monatsschr Pharm 19 1965 38 39
    • (1965) Med Monatsschr Pharm , vol.19 , pp. 38-39
    • Mathies, H.1    Willms, D.2
  • 145
    • 0014861115 scopus 로고
    • Effects of natural and semisynthetic polysaccharides on connective tissue metabolism
    • Kalbhen D.A. Karzel K. Dinnendahl V. Domenjoz R. Effects of natural and semisynthetic polysaccharides on connective tissue metabolism Arzneimittelforschung 20 1970 1479 1482
    • (1970) Arzneimittelforschung , vol.20 , pp. 1479-1482
    • Kalbhen, D.A.1    Karzel, K.2    Dinnendahl, V.3    Domenjoz, R.4
  • 147
    • 85119816992 scopus 로고    scopus 로고
    • Modulation of matrix metalloproteinase activities in osteoarthritic cartilage by calcium xylopyranose polysulfate
    • (accepted for presentation) Ghosh P. Xu A. Little C. Modulation of matrix metalloproteinase activities in osteoarthritic cartilage by calcium xylopyranose polysulfate Combined Orthop Res Soc Meeting Hamamatsu, Japan September 28–30, 1998
    • (1998)
    • Ghosh, P.1    Xu, A.2    Little, C.3
  • 148
    • 0015515303 scopus 로고
    • Zur Beeinflussung des katabolen Mucopolysaccharidstoffwechsels durch SP54
    • Platt D. Zur Beeinflussung des katabolen Mucopolysaccharidstoffwechsels durch SP54 Med Welt 23 1972 1767 1768
    • (1972) Med Welt , vol.23 , pp. 1767-1768
    • Platt, D.1
  • 149
    • 0016923370 scopus 로고
    • Untersuchungen uber den durch leukozytare Enzyme stimulierten Abbau von norpelgewebe and seine Beeinflussung durch antirheumatische Arzneimittel
    • Leiss C. Kalbhen D.A. Untersuchungen uber den durch leukozytare Enzyme stimulierten Abbau von norpelgewebe and seine Beeinflussung durch antirheumatische Arzneimittel Arzneimittelforschung 26 1976 165 169
    • (1976) Arzneimittelforschung , vol.26 , pp. 165-169
    • Leiss, C.1    Kalbhen, D.A.2
  • 150
    • 0017198329 scopus 로고
    • Purification and some properties of a neutral protease from human leukocyte granules and its comparison with pancreatic elastase
    • Kruze D. Menninger H. Fehr K. Boni A. Böni A. Purification and some properties of a neutral protease from human leukocyte granules and its comparison with pancreatic elastase Biochim Biophys Acta 438 1976 503 513
    • (1976) Biochim Biophys Acta , vol.438 , pp. 503-513
    • Kruze, D.1    Menninger, H.2    Fehr, K.3    Boni, A.4    Böni, A.5
  • 151
    • 0017228263 scopus 로고
    • Effect of antirheumatic drugs on cathepsin B1 from bovine spleen
    • Kruze D. Fehr K. Boni A. Böni A. Effect of antirheumatic drugs on cathepsin B1 from bovine spleen Z Rheumatol 35 1976 95 102
    • (1976) Z Rheumatol , vol.35 , pp. 95-102
    • Kruze, D.1    Fehr, K.2    Boni, A.3    Böni, A.4
  • 152
    • 0027588233 scopus 로고
    • Treatment of canine osteoarthritis with insulin-like growth factor-1 (IGF-1) and sodium pentosan polysulfate
    • Rogachefsky R.A. Dean D.D. Howell D.S. Altman R.D. Treatment of canine osteoarthritis with insulin-like growth factor-1 (IGF-1) and sodium pentosan polysulfate Osteoarthritis Cart 1 1993 105 114
    • (1993) Osteoarthritis Cart , vol.1 , pp. 105-114
    • Rogachefsky, R.A.1    Dean, D.D.2    Howell, D.S.3    Altman, R.D.4
  • 154
    • 0026640291 scopus 로고
    • The chondroprotective drugs, arteparon and sodium pentosan polysulphate,increase collagenase activity and inhibit stromelysin activity in vitro
    • Nethery A. Giles I. Jenkins K. Jackson C. Brooks P. Burkhardt D. The chondroprotective drugs, arteparon and sodium pentosan polysulphate,increase collagenase activity and inhibit stromelysin activity in vitro Biochem Pharmacol 44 1992 1549 1553
    • (1992) Biochem Pharmacol , vol.44 , pp. 1549-1553
    • Nethery, A.1    Giles, I.2    Jenkins, K.3    Jackson, C.4    Brooks, P.5    Burkhardt, D.6
  • 155
    • 85119794277 scopus 로고    scopus 로고
    • ILl-B stimulated collagenase-3 gene upregulation chondrocytes: suppression by pentosan polysulfate
    • Grumbles R.M. Shao L. Jeffrey J.J. Howell D.S. ILl-B stimulated collagenase-3 gene upregulation chondrocytes: suppression by pentosan polysulfate Trans Orthop Res Soc 23 1998 917
    • (1998) Trans Orthop Res Soc , vol.23 , pp. 917
    • Grumbles, R.M.1    Shao, L.2    Jeffrey, J.J.3    Howell, D.S.4
  • 156
    • 0030451069 scopus 로고    scopus 로고
    • Regulation of rat interstitial collagenase gene expression in growth cartilage and chondrocytes by vitamin D-3, interleukin-1-beta, and okadaicacid
    • Grumbles R.M. Shao L. Jeffrey J.J. Howell D.S. Regulation of rat interstitial collagenase gene expression in growth cartilage and chondrocytes by vitamin D-3, interleukin-1-beta, and okadaicacid J Cell Biol 63 1996 395 409
    • (1996) J Cell Biol , vol.63 , pp. 395-409
    • Grumbles, R.M.1    Shao, L.2    Jeffrey, J.J.3    Howell, D.S.4
  • 157
    • 0026585265 scopus 로고
    • Trans-repressor activity of nuclear glycosaminoglycans on Fos and Jun/AP-1 oncoprotein-mediated transcription
    • Busch S.J. Martin G.A. Barnhart R.L Mano M. Cardin A.D. Jackson R.L. Trans-repressor activity of nuclear glycosaminoglycans on Fos and Jun/AP-1 oncoprotein-mediated transcription J Cell Biol 116 1992 31 42
    • (1992) J Cell Biol , vol.116 , pp. 31-42
    • Busch, S.J.1    Martin, G.A.2    Barnhart, R.L3    Mano, M.4    Cardin, A.D.5    Jackson, R.L.6
  • 158
    • 0020661241 scopus 로고
    • Drugs for osteoarthrosis 1: the effects of pentosan polysulphate (SP54) on the degradation and loss of proteoglycans from articular cartilage in a model of osteoarthrosis induced in the rabbit knee joint by immobilization
    • Golding J.C. Ghosh P. Drugs for osteoarthrosis 1: the effects of pentosan polysulphate (SP54) on the degradation and loss of proteoglycans from articular cartilage in a model of osteoarthrosis induced in the rabbit knee joint by immobilization Curr Ther Res 33 1983 173 184
    • (1983) Curr Ther Res , vol.33 , pp. 173-184
    • Golding, J.C.1    Ghosh, P.2
  • 159
    • 85119791961 scopus 로고
    • Theoretisches Konzept and experimentelle Bestatigung for ein Arthrose-Modell am Versuchstier
    • Kalbhen D.A Blum U. Theoretisches Konzept and experimentelle Bestatigung for ein Arthrose-Modell am Versuchstier Arzneimittelforschung 27 1977
    • (1977) Arzneimittelforschung , vol.27
    • Kalbhen, D.A1    Blum, U.2
  • 160
    • 85119815446 scopus 로고
    • Cartilage degradation and repair: a brief review of chondroprotective treatment
    • Howell D.S. Kapila P. Malinin T.I. Altman R.D. Cartilage degradation and repair: a brief review of chondroprotective treatment Excerpta Medica 3 1987 13
    • (1987) Excerpta Medica , vol.3 , pp. 13
    • Howell, D.S.1    Kapila, P.2    Malinin, T.I.3    Altman, R.D.4
  • 161
    • 0022669559 scopus 로고
    • Pathological, biochemical and experimental therapeutic studies in meniscectomy models of osteoarthritis in the rabbit: its relationship to human joint pathology
    • (Suppl) Malemud C.J. Goldberg V.M. Moskowitz R.W. Pathological, biochemical and experimental therapeutic studies in meniscectomy models of osteoarthritis in the rabbit: its relationship to human joint pathology Br J Clin Pathol 40 1986 21 31
    • (1986) Br J Clin Pathol , vol.40 , pp. 21-31
    • Malemud, C.J.1    Goldberg, V.M.2    Moskowitz, R.W.3
  • 162
    • 0015046195 scopus 로고
    • Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical andmetabolic data
    • Mankin H.J. Dorfman H. Lippiello L. Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical andmetabolic data J Bone Joint Surg Am 53 1971 523 537
    • (1971) J Bone Joint Surg Am , vol.53 , pp. 523-537
    • Mankin, H.J.1    Dorfman, H.2    Lippiello, L.3    Zarins, A.4
  • 164
    • 0030875073 scopus 로고    scopus 로고
    • Expression of membrane type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage
    • Imai K. Ohta S. Matsumoto T. Fujimoto N. Sato H. Seik M. Expression of membrane type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage Am J Pathol 151 1997 245 256
    • (1997) Am J Pathol , vol.151 , pp. 245-256
    • Imai, K.1    Ohta, S.2    Matsumoto, T.3    Fujimoto, N.4    Sato, H.5    Seik, M.6
  • 166
    • 0019511192 scopus 로고
    • Proteoglycan aggregate synthesis in normal and chronically hydrocortisone-suppressed rabbit articular cartilage
    • Oegema T.R. Jr Behrens E. Proteoglycan aggregate synthesis in normal and chronically hydrocortisone-suppressed rabbit articular cartilage Arch Biochem Biophys 206 1981 77
    • (1981) Arch Biochem Biophys , vol.206 , pp. 77
    • Oegema, T.R.1    Behrens, E.2
  • 167
    • 0024846235 scopus 로고
    • Pentosan polysulfate (Cartrophen) prevents the hydrocortisone induced loss of hyaluronac acid and proteoglycans from cartilage of rabbit joints as well as normalizes the keratan sulfate levels in their serum
    • Kongtawelert P. Brooks P. Ghosh P. Pentosan polysulfate (Cartrophen) prevents the hydrocortisone induced loss of hyaluronac acid and proteoglycans from cartilage of rabbit joints as well as normalizes the keratan sulfate levels in their serum J Rheumatol 16 1989 1454 1459
    • (1989) J Rheumatol , vol.16 , pp. 1454-1459
    • Kongtawelert, P.1    Brooks, P.2    Ghosh, P.3
  • 168
    • 85119810288 scopus 로고
    • The development and application of immunosorbent assays for the quantitation of hyaluronan and sulphated polysaccharides
    • Kongtawelert P. The development and application of immunosorbent assays for the quantitation of hyaluronan and sulphated polysaccharides Ph.D. thesis 1991 University of Sydney
    • (1991)
    • Kongtawelert, P.1
  • 169
    • 0023237837 scopus 로고
    • A pharmacological and histological examination of the microcirculation of the rat subcutaneous air-pouch: microcirculation of the rat air-pouch
    • Takagi T. Forrest M.J. Brooks P.M. A pharmacological and histological examination of the microcirculation of the rat subcutaneous air-pouch: microcirculation of the rat air-pouch Pathology 19 1987 294 298
    • (1987) Pathology , vol.19 , pp. 294-298
    • Takagi, T.1    Forrest, M.J.2    Brooks, P.M.3
  • 170
    • 0019424377 scopus 로고
    • The formation of a structure with the features of synovial lining by subcutaneous injection of air: an in vivo tissue culture system
    • Edwards J.C.W. Sedgwick A.D. Willoughby D.A. The formation of a structure with the features of synovial lining by subcutaneous injection of air: an in vivo tissue culture system J Pathol 134 1981 147 156
    • (1981) J Pathol , vol.134 , pp. 147-156
    • Edwards, J.C.W.1    Sedgwick, A.D.2    Willoughby, D.A.3
  • 171
    • 0009483567 scopus 로고
    • The subcutaneous air-pouch model of inflammation
    • Forrest M.J Brooks P.M. Takagi T. Kowanko I. The subcutaneous air-pouch model of inflammation Greenwald R.A Diamond H.S. Handbook of animal models for rheumatic diseases 1987 CRC Press Boca Raton, FL 125 134
    • (1987) , pp. 125-134
    • Forrest, M.J1    Brooks, P.M.2    Takagi, T.3    Kowanko, I.4
  • 172
    • 0024405581 scopus 로고
    • Retardation of articular cartilage degradation by glycosaminoglycan polysulfate, pentosan polysulfate, and DH-40J in the rat air pouch model
    • Francis D.J. Forrest M.J. Brooks P.M. Ghosh P. Retardation of articular cartilage degradation by glycosaminoglycan polysulfate, pentosan polysulfate, and DH-40J in the rat air pouch model Arthritis Rheum 32 1989 608 616
    • (1989) Arthritis Rheum , vol.32 , pp. 608-616
    • Francis, D.J.1    Forrest, M.J.2    Brooks, P.M.3    Ghosh, P.4
  • 173
    • 85119804968 scopus 로고
    • Studies on articular cartilage turnover in an animal model of inflammation
    • Francis D. Studies on articular cartilage turnover in an animal model of inflammation PhD Thesis 1991 University of Sydney
    • (1991)
    • Francis, D.1
  • 174
    • 0024450340 scopus 로고
    • Application of an enzyme-linked immunosorbent-inhibition assay to quantitate the release of KS peptides into fluids of the rat subcutaneousair-pouch model and the effects of chondroprotective drugs on the release process
    • Kongtawelert P. Francis D.J. Brooks P.M. Ghosh P. Application of an enzyme-linked immunosorbent-inhibition assay to quantitate the release of KS peptides into fluids of the rat subcutaneousair-pouch model and the effects of chondroprotective drugs on the release process Rheumatol Int 9 1989 77 83
    • (1989) Rheumatol Int , vol.9 , pp. 77-83
    • Kongtawelert, P.1    Francis, D.J.2    Brooks, P.M.3    Ghosh, P.4
  • 175
    • 84933349653 scopus 로고
    • Aspects of experimental inflammatory arthritis
    • Page-Thomas D.P. Aspects of experimental inflammatory arthritis Rheumatoid Arthritis 1977 173 179
    • (1977) Rheumatoid Arthritis , pp. 173-179
    • Page-Thomas, D.P.1
  • 176
    • 0027955687 scopus 로고
    • The effects of orally administered calcium pentosan polysulphate on inflammation and cartilage degradation produced in rabbit joints byintraarticular injection of a hyaluronate-polylysine complex
    • Smith M.M. Ghosh P. Numata Y. Bansal M.K. The effects of orally administered calcium pentosan polysulphate on inflammation and cartilage degradation produced in rabbit joints byintraarticular injection of a hyaluronate-polylysine complex Arthritis Rheum 37 1994 125 136
    • (1994) Arthritis Rheum , vol.37 , pp. 125-136
    • Smith, M.M.1    Ghosh, P.2    Numata, Y.3    Bansal, M.K.4
  • 177
    • 85119803272 scopus 로고    scopus 로고
    • Preservation of chondrocyte and synoviocyte metabolism (cytoprotection) by oral calcium pentosan polysulphate in a lapine model of inflammatoryarthritis
    • Smith M.M. Numata Y. Bowman L. Ghosh P. Preservation of chondrocyte and synoviocyte metabolism (cytoprotection) by oral calcium pentosan polysulphate in a lapine model of inflammatoryarthritis Osteoarthritis Cart 4 1996 ii iii
    • (1996) Osteoarthritis Cart , vol.4 , pp. ii-iii
    • Smith, M.M.1    Numata, Y.2    Bowman, L.3    Ghosh, P.4
  • 178
    • 85119792050 scopus 로고    scopus 로고
    • Effects of calcium xylopyranose polysulphate in an animal model of inflammation
    • Conaghan P.G. Smith M.M. Brooks P. Ghosh P. Effects of calcium xylopyranose polysulphate in an animal model of inflammation Osteoarthritis Cartilage 5 1997 62
    • (1997) Osteoarthritis Cartilage , vol.5 , pp. 62
    • Conaghan, P.G.1    Smith, M.M.2    Brooks, P.3    Ghosh, P.4
  • 179
    • 0028306396 scopus 로고
    • Animal models for osteoarthritis: processes, problems and prospects
    • Pritzker K.P. Animal models for osteoarthritis: processes, problems and prospects Ann Rheum Dis 53 1994 406 420
    • (1994) Ann Rheum Dis , vol.53 , pp. 406-420
    • Pritzker, K.P.1
  • 180
    • 0025115855 scopus 로고
    • Synovitis and osteoarthritic changes in canine articular cartilage after anterior cruciate ligament transection: effect of surgical hemostasis
    • Myers S.L. Brandt K.D. O'Connor B.L. Visco D.M. Albrecht M.E. Synovitis and osteoarthritic changes in canine articular cartilage after anterior cruciate ligament transection: effect of surgical hemostasis Arthritis Rheum 33 1990 1406 1415
    • (1990) Arthritis Rheum , vol.33 , pp. 1406-1415
    • Myers, S.L.1    Brandt, K.D.2    O'Connor, B.L.3    Visco, D.M.4    Albrecht, M.E.5
  • 181
    • 0017894737 scopus 로고
    • The synovial changes in post-traumatic synovitis and osteoarthritis
    • Soren A. Klein W. Huth E. The synovial changes in post-traumatic synovitis and osteoarthritis Rheumatol Rehabil 17 1978 38 44
    • (1978) Rheumatol Rehabil , vol.17 , pp. 38-44
    • Soren, A.1    Klein, W.2    Huth, E.3
  • 182
    • 0021873228 scopus 로고
    • Inflammation in osteoarthritis
    • Altman R.D. Gray R. Inflammation in osteoarthritis Clin Rheum Dis 11 1985 353 365
    • (1985) Clin Rheum Dis , vol.11 , pp. 353-365
    • Altman, R.D.1    Gray, R.2
  • 184
    • 0023942493 scopus 로고
    • Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides
    • Houssiau F.A. Devogelaer J-P. Van Damme J. de Deuxchaisnes C.N. Van Snick J. Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides Arthritis Rheum 31 1988 784 788
    • (1988) Arthritis Rheum , vol.31 , pp. 784-788
    • Houssiau, F.A.1    Devogelaer, J-P.2    Van Damme, J.3    de Deuxchaisnes, C.N.4    Van Snick, J.5
  • 185
    • 0026527781 scopus 로고
    • Interleukin 6 levels in synovial fluids of patients with different arthritides: correlation with local IGM rheumatoid factor and systemic acutephase protein production
    • Brozik M. Rosztoczy I. Meretey K. Balint G. Gaal M. Balogh Z. Interleukin 6 levels in synovial fluids of patients with different arthritides: correlation with local IGM rheumatoid factor and systemic acutephase protein production J Rheumatol 19 1992 63 68
    • (1992) J Rheumatol , vol.19 , pp. 63-68
    • Brozik, M.1    Rosztoczy, I.2    Meretey, K.3    Balint, G.4    Gaal, M.5    Balogh, Z.6
  • 186
    • 0028950161 scopus 로고
    • Comparison of blood and synovial fluid lymphocyte subsets in rheumatoid arthritis and osteoarthritis
    • Kuryliszyn-Moskal A. Comparison of blood and synovial fluid lymphocyte subsets in rheumatoid arthritis and osteoarthritis Clin Rheumatol 14 1995 43 50
    • (1995) Clin Rheumatol , vol.14 , pp. 43-50
    • Kuryliszyn-Moskal, A.1
  • 187
    • 0029075028 scopus 로고
    • Microheterogeneity of acute phase proteins in patients with clinically active and clinically nonactive osteoarthritis
    • Hrycaj P. Stratz T. Kovac C. Mennet P. Müller W. Microheterogeneity of acute phase proteins in patients with clinically active and clinically nonactive osteoarthritis Clin Rheumatol 14 1995 434 440
    • (1995) Clin Rheumatol , vol.14 , pp. 434-440
    • Hrycaj, P.1    Stratz, T.2    Kovac, C.3    Mennet, P.4    Müller, W.5
  • 188
    • 0029895089 scopus 로고    scopus 로고
    • Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies
    • Schlaak J.F. Pfers I. Meyer zum Biischenfelde K-H. Märker-Hermann E. Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies Clin Exp Rheumatol 14 1996 155 162
    • (1996) Clin Exp Rheumatol , vol.14 , pp. 155-162
    • Schlaak, J.F.1    Pfers, I.2    Meyer zum Biischenfelde, K-H.3    Märker-Hermann, E.4
  • 189
    • 0031020841 scopus 로고    scopus 로고
    • Evaluation of synovial cytokine patterns in rheumatoid arthritis and osteoarthritis by quantitative reverse transcription polymerase chain reaction
    • Wagner S. Fritz P. Einsele H. Sell S. Saal J.G. Evaluation of synovial cytokine patterns in rheumatoid arthritis and osteoarthritis by quantitative reverse transcription polymerase chain reaction Rheumatol Int 16 1997 191 196
    • (1997) Rheumatol Int , vol.16 , pp. 191-196
    • Wagner, S.1    Fritz, P.2    Einsele, H.3    Sell, S.4    Saal, J.G.5
  • 190
    • 0029862818 scopus 로고    scopus 로고
    • Oncoprotein expression in human synovial tissue: an immunohistochemical study of different types of arthritis
    • Roivainen A. Söderstrom K.O. Pirila L. Aro H. Kortekangas P. Merilahti-Palo R. Oncoprotein expression in human synovial tissue: an immunohistochemical study of different types of arthritis Br J Rheumatol 35 1996 933 942
    • (1996) Br J Rheumatol , vol.35 , pp. 933-942
    • Roivainen, A.1    Söderstrom, K.O.2    Pirila, L.3    Aro, H.4    Kortekangas, P.5    Merilahti-Palo, R.6
  • 192
    • 0024352667 scopus 로고
    • Increased levels of proteoglycan fragments in knee joint fluid after injury
    • Lohmander L.S. Dahlberg L. Ryd L. Heinegård D. Increased levels of proteoglycan fragments in knee joint fluid after injury Arthritis Rheum 32 1989 1434 1442
    • (1989) Arthritis Rheum , vol.32 , pp. 1434-1442
    • Lohmander, L.S.1    Dahlberg, L.2    Ryd, L.3    Heinegård, D.4
  • 193
    • 0026710173 scopus 로고
    • Synovial fluid analysis of two groups of proteoglycan epitopes distinguishes early and late cartilage lesions
    • Saxne T. Heinegård D. Synovial fluid analysis of two groups of proteoglycan epitopes distinguishes early and late cartilage lesions Arthritis Rheum 35 1992 385 390
    • (1992) Arthritis Rheum , vol.35 , pp. 385-390
    • Saxne, T.1    Heinegård, D.2
  • 194
    • 0028277789 scopus 로고
    • Articular cartilage and osteoarthrosis: the role of molecular markers to monitor breakdown, repair and disease
    • Lohmander L.S. Articular cartilage and osteoarthrosis: the role of molecular markers to monitor breakdown, repair and disease J Anat 184 1994 477 492
    • (1994) J Anat , vol.184 , pp. 477-492
    • Lohmander, L.S.1
  • 195
    • 0028556811 scopus 로고
    • Longitudinal study of cartilage matrix metabolism in patients with cruciate ligament rupture: synovial fluid concentrations of aggrecan fragments, stromelysin-1 and tissue inhibitor of metalloproteinase-1
    • Dahlberg L. Friden T. Roos H. Lark M.W. Lohmander L.S. Longitudinal study of cartilage matrix metabolism in patients with cruciate ligament rupture: synovial fluid concentrations of aggrecan fragments, stromelysin-1 and tissue inhibitor of metalloproteinase-1 Br J Rheumatol 33 1994 1107 1111
    • (1994) Br J Rheumatol , vol.33 , pp. 1107-1111
    • Dahlberg, L.1    Friden, T.2    Roos, H.3    Lark, M.W.4    Lohmander, L.S.5
  • 196
    • 0028201852 scopus 로고
    • Temporal patterns of stromelysin-1, tissue inhibitor, and proteoglycan fragments in human knee joint fluid after injury to the cruciate ligament ormeniscus
    • Lohmander L.S. Roos H. Dahlberg L. Hoermer L.A. Lark M.W. Temporal patterns of stromelysin-1, tissue inhibitor, and proteoglycan fragments in human knee joint fluid after injury to the cruciate ligament ormeniscus J Orthop Res 12 1994 21 28
    • (1994) J Orthop Res , vol.12 , pp. 21-28
    • Lohmander, L.S.1    Roos, H.2    Dahlberg, L.3    Hoermer, L.A.4    Lark, M.W.5
  • 197
    • 0002636311 scopus 로고
    • Immune response to cartilage proteoglycans in inflammatory canimal models and human diseases
    • Glant T.T. Mikecz K. Kuettner K.E. Thonar E.J.-M.A. Immune response to cartilage proteoglycans in inflammatory canimal models and human diseases Woessner F. Howell D. Joint cartilage degradation: basic and clinical aspects 1992 Dekker New York 435 473
    • (1992) , pp. 435-473
    • Glant, T.T.1    Mikecz, K.2    Kuettner, K.E.3    Thonar, E.J.-M.A.4
  • 198
    • 0021139215 scopus 로고
    • Connective tissue antigens stimulate collagenase production in arthritic diseases
    • Golds E.E. Poole A.R. Connective tissue antigens stimulate collagenase production in arthritic diseases Cell Immunol 86 1984 190 205
    • (1984) Cell Immunol , vol.86 , pp. 190-205
    • Golds, E.E.1    Poole, A.R.2
  • 199
    • 0020045873 scopus 로고
    • Cartilage specific collagen activates macrophages and the alternative pathway of complement: evidence for an immunopathogenic concept of rheumatoidarthritis
    • Hanauske-Able H.M. Pontz B.F. Schorlemmer H.U. Cartilage specific collagen activates macrophages and the alternative pathway of complement: evidence for an immunopathogenic concept of rheumatoidarthritis Ann Rheum Dis 41 1982 168 176
    • (1982) Ann Rheum Dis , vol.41 , pp. 168-176
    • Hanauske-Able, H.M.1    Pontz, B.F.2    Schorlemmer, H.U.3
  • 200
    • 0025084542 scopus 로고
    • Cellular immune response toward human articular chondrocytes: T cell reactivities against chondrocyte and fibroblast membranes in destructive jointdiseases
    • Alsalameh S. Mollenhauer J. Hain N. Stock K-P. Kalden J.R. Burmester G.R. Cellular immune response toward human articular chondrocytes: T cell reactivities against chondrocyte and fibroblast membranes in destructive jointdiseases Arthritis Rheum 33 1990 1477 1486
    • (1990) Arthritis Rheum , vol.33 , pp. 1477-1486
    • Alsalameh, S.1    Mollenhauer, J.2    Hain, N.3    Stock, K-P.4    Kalden, J.R.5    Burmester, G.R.6
  • 201
    • 0026561185 scopus 로고
    • Immunity to cartilage proteoglycans
    • Banerjee S. Poole A.R. Immunity to cartilage proteoglycans J Rheumatol 19 1992 36 39
    • (1992) J Rheumatol , vol.19 , pp. 36-39
    • Banerjee, S.1    Poole, A.R.2
  • 203
    • 0021320010 scopus 로고
    • Experimental arthritis induced by intruarticular injection of allogenic cartilaginous particles into rabbit knees
    • Evans C.H. Mazzocchi R.A. Nelson D.D. Rubash H.E. Experimental arthritis induced by intruarticular injection of allogenic cartilaginous particles into rabbit knees Arthritis Rheum 27 1984 200 207
    • (1984) Arthritis Rheum , vol.27 , pp. 200-207
    • Evans, C.H.1    Mazzocchi, R.A.2    Nelson, D.D.3    Rubash, H.E.4
  • 204
    • 0032522487 scopus 로고    scopus 로고
    • Critical roles of glycosaminoglycan side chains of cartilage proteoglycans (aggrecan) in antigen recognition and presentation
    • Glant T. Buzas E.I. Finnegan A. Negroiu G. Cs-Szabo G. Mikecz K. Critical roles of glycosaminoglycan side chains of cartilage proteoglycans (aggrecan) in antigen recognition and presentation J Immunol 160 1998 3812 3819
    • (1998) J Immunol , vol.160 , pp. 3812-3819
    • Glant, T.1    Buzas, E.I.2    Finnegan, A.3    Negroiu, G.4    Cs-Szabo, G.5    Mikecz, K.6
  • 205
    • 0023114810 scopus 로고
    • Epitopes of proteoglycans eliciting an anti-proteoglycan response in chronic immune synovitis
    • Yoo J.U. Kresina T.F. Malemud C.J. Goldberg V.M. Epitopes of proteoglycans eliciting an anti-proteoglycan response in chronic immune synovitis Proc Natl Acad Sci USA 84 1987 832 836
    • (1987) , pp. 832-836
    • Yoo, J.U.1    Kresina, T.F.2    Malemud, C.J.3    Goldberg, V.M.4
  • 206
    • 0023860761 scopus 로고
    • Evidence that a Immoral immune-response to autologous cartilage proteoglycan can participate in the induction of cartilage pathology
    • Kresina T.F. Yoo J.U. Glodberg V.M. Evidence that a Immoral immune-response to autologous cartilage proteoglycan can participate in the induction of cartilage pathology Arthritis Rheum 31 1988 248 257
    • (1988) Arthritis Rheum , vol.31 , pp. 248-257
    • Kresina, T.F.1    Yoo, J.U.2    Glodberg, V.M.3
  • 207
  • 208
    • 0025319273 scopus 로고
    • Increased interleukin-1-beta production of macrophages by proteoglycan fragments deriving from articular cartilage in vitro
    • Gurr E. Ahrens A. Lonneman G. Delbruck A. Increased interleukin-1-beta production of macrophages by proteoglycan fragments deriving from articular cartilage in vitro Agents Actions 29 1990 117 119
    • (1990) Agents Actions , vol.29 , pp. 117-119
    • Gurr, E.1    Ahrens, A.2    Lonneman, G.3    Delbruck, A.4
  • 209
    • 0027257258 scopus 로고
    • Autoimmune recognition of cartilage collagens
    • Holmdahl R. Malmstrom V. Vourio E. Autoimmune recognition of cartilage collagens Ann Med 25 1993 251 264
    • (1993) Ann Med , vol.25 , pp. 251-264
    • Holmdahl, R.1    Malmstrom, V.2    Vourio, E.3
  • 210
    • 0018259510 scopus 로고
    • The biochemical and pharmacological basis of the antiphlogistic/anfrheumatic effect of pentosan polysulphate
    • Kalbhen D.A. The biochemical and pharmacological basis of the antiphlogistic/anfrheumatic effect of pentosan polysulphate Wein Klin Wochenschr 90 1978 101 105
    • (1978) Wein Klin Wochenschr , vol.90 , pp. 101-105
    • Kalbhen, D.A.1
  • 211
    • 0018259510 scopus 로고
    • Biochemisch-phannakologische Grundlagen zur antiphlogistisch-antirheumatischen Wirkung von Pentosanpolysulfat
    • Kalbhen D.A. Biochemisch-phannakologische Grundlagen zur antiphlogistisch-antirheumatischen Wirkung von Pentosanpolysulfat Wien. Klin Wochenschr 90 1978 101 105
    • (1978) Wien. Klin Wochenschr , vol.90 , pp. 101-105
    • Kalbhen, D.A.1
  • 212
    • 34147199849 scopus 로고
    • Entzündungshemmung durch Pentosanpolysulfat
    • Kalbhen D.A. Entzündungshemmung durch Pentosanpolysulfat Dtsch Med Wochenschr 97 1972 1 3
    • (1972) Dtsch Med Wochenschr , vol.97 , pp. 1-3
    • Kalbhen, D.A.1
  • 213
    • 0015551050 scopus 로고
    • Pharmacological studies on the antiinflammatory effect of a semi-synthetic polysaccharide (pentosan polysulfate)
    • Kalbhen D.A. Pharmacological studies on the antiinflammatory effect of a semi-synthetic polysaccharide (pentosan polysulfate) Pharmacology 9 1973 74 79
    • (1973) Pharmacology , vol.9 , pp. 74-79
    • Kalbhen, D.A.1
  • 214
    • 0014903922 scopus 로고
    • Erste Untersuchungen zur entzundungshemmenden Wirkung von Pentosanpolysulfat auf verschiedene Odemformen der Rattenpfote
    • Kalbhen D.A. Clausen H. Domenjoz R. Erste Untersuchungen zur entzundungshemmenden Wirkung von Pentosanpolysulfat auf verschiedene Odemformen der Rattenpfote Arzneimittelforschung 20 1970 1872 1874
    • (1970) Arzneimittelforschung , vol.20 , pp. 1872-1874
    • Kalbhen, D.A.1    Clausen, H.2    Domenjoz, R.3
  • 215
    • 0015623471 scopus 로고
    • Pharmakologische Untersuchungen zur entzündungshemmenden Wirkung von Pentosanpolysulfat (SP54) in Kombination mit anderenAnalgetika/Antiphlogistika
    • Kalbhen D.A. Fischer W. Pharmakologische Untersuchungen zur entzündungshemmenden Wirkung von Pentosanpolysulfat (SP54) in Kombination mit anderenAnalgetika/Antiphlogistika Arzneimittelforschung 23 1973 712 718
    • (1973) Arzneimittelforschung , vol.23 , pp. 712-718
    • Kalbhen, D.A.1    Fischer, W.2
  • 216
    • 0015133712 scopus 로고
    • Zur antiphlogistischen Wirkung von Pentosanpolysulfat auf das experimentelle Pfotenödem der Ratte
    • Kalbhen D.A Van Heck H.J. Zur antiphlogistischen Wirkung von Pentosanpolysulfat auf das experimentelle Pfotenödem der Ratte Arzneimittelforschung 21 1971 1608 1612
    • (1971) Arzneimittelforschung , vol.21 , pp. 1608-1612
    • Kalbhen, D.A1    Van Heck, H.J.2
  • 217
    • 0015063663 scopus 로고
    • Antikomplementare Wirkung eines semisynthetischen Pentosan-Polysulfo-Esters In-vitro-Untersuchungen uber Angriffspunkt und Wirkungsunterschiede zumHeparin
    • Walb D. Loos M. Hadding U. Antikomplementare Wirkung eines semisynthetischen Pentosan-Polysulfo-Esters In-vitro-Untersuchungen uber Angriffspunkt und Wirkungsunterschiede zumHeparin Zschr Naturforsch 26 1971 403 408
    • (1971) Zschr Naturforsch , vol.26 , pp. 403-408
    • Walb, D.1    Loos, M.2    Hadding, U.3
  • 218
    • 0017617295 scopus 로고
    • Anticomplementary activity of a polyanion. Pentosan poly sulfoester. II. Mode of action and in vitro inhibition of human complement hemolyticactivity
    • Berthoux F.C Freyria A-M. Traeger J. Anticomplementary activity of a polyanion. Pentosan poly sulfoester. II. Mode of action and in vitro inhibition of human complement hemolyticactivity Pathol Biol 25 1977 105 108
    • (1977) Pathol Biol , vol.25 , pp. 105-108
    • Berthoux, F.C1    Freyria, A-M.2    Traeger, J.3
  • 219
    • 0017364510 scopus 로고
    • Anticomplementary activity of a polyanion, pentosan poly-sulfoester. III. Mechanism of functional inactivation of the different properdin andcomplement system molecules
    • Berthoux F.C. Freyria A-J. Traeger J. Anticomplementary activity of a polyanion, pentosan poly-sulfoester. III. Mechanism of functional inactivation of the different properdin andcomplement system molecules Pathol Biol 25 1977 179 184
    • (1977) Pathol Biol , vol.25 , pp. 179-184
    • Berthoux, F.C.1    Freyria, A-J.2    Traeger, J.3
  • 220
    • 0017446944 scopus 로고
    • Anticomplementary activity of a polyanion: pentosan-polysulfoester. I. in vitro study and in vivo trial in human glomerulonephritis
    • Berthoux F.C. Freyria A-M. Zech P-Y. Traeger J. Anticomplementary activity of a polyanion: pentosan-polysulfoester. I. in vitro study and in vivo trial in human glomerulonephritis Pathol Biol 25 1977 33 36
    • (1977) Pathol Biol , vol.25 , pp. 33-36
    • Berthoux, F.C.1    Freyria, A-M.2    Zech, P-Y.3    Traeger, J.4
  • 221
    • 0031808657 scopus 로고    scopus 로고
    • The semisynthetic polysaccharide pentosan polysulphate prevents complement-mediated myocardial injury in rabbit perfused heart
    • Kilgore K.S. Naylor K.B. Tanhehco E.J. Park J.L. Booth E.A. Washington R.A. The semisynthetic polysaccharide pentosan polysulphate prevents complement-mediated myocardial injury in rabbit perfused heart J Pharm Exp Ther 285 1998 987 994
    • (1998) J Pharm Exp Ther , vol.285 , pp. 987-994
    • Kilgore, K.S.1    Naylor, K.B.2    Tanhehco, E.J.3    Park, J.L.4    Booth, E.A.5    Washington, R.A.6
  • 222
    • 85119804834 scopus 로고    scopus 로고
    • Smith MM, Ghosh P, Numata Y, Conaghan P, Calciumxylopyranose polysulfate (CaXPS) modulates cytokine, NO and disease activity in a new rat model of inflammatory arthritis. Osteoarthritis and Cartilage (in press).
  • 223
    • 0030750273 scopus 로고    scopus 로고
    • Immunolocalization of inducible nitric oxide synthase in synovium and cartilage in rheumatoid arthritis and osteoarthritis
    • Grabowski P.S. Wright P.K. Vanthof R.J. Helfrich M.H. Ohshima H. Ralston S.H. Immunolocalization of inducible nitric oxide synthase in synovium and cartilage in rheumatoid arthritis and osteoarthritis Br J Rheumatol 36 1997 651 655
    • (1997) Br J Rheumatol , vol.36 , pp. 651-655
    • Grabowski, P.S.1    Wright, P.K.2    Vanthof, R.J.3    Helfrich, M.H.4    Ohshima, H.5    Ralston, S.H.6
  • 224
    • 0027930284 scopus 로고
    • Nitric oxide and proteoglycan biosynthesis by human articular chondrocytes in alginate culture
    • Häuselmann H.J. Oppliger L. Michel B.A. StefanovicRacic M. Evans C.H. Nitric oxide and proteoglycan biosynthesis by human articular chondrocytes in alginate culture FEBS Lett 352 1994 361 364
    • (1994) FEBS Lett , vol.352 , pp. 361-364
    • Häuselmann, H.J.1    Oppliger, L.2    Michel, B.A.3    StefanovicRacic, M.4    Evans, C.H.5
  • 225
    • 0027772101 scopus 로고
    • The effects of CaPPS on inflammatory mediators in the rat subcutaneous air-pouch model of inflammation
    • Bansal M. Smith M.M. Numata Y. Ghosh P. The effects of CaPPS on inflammatory mediators in the rat subcutaneous air-pouch model of inflammation Curr Ther Res 54 1993 714 730
    • (1993) Curr Ther Res , vol.54 , pp. 714-730
    • Bansal, M.1    Smith, M.M.2    Numata, Y.3    Ghosh, P.4
  • 226
    • 0026487219 scopus 로고
    • Inflammatory cytokines and enzymes in synovial fluid of patients with rheumatoid arthritis and other arthritides
    • Yoshida K. Kobayashi K. Yamagata N. Iwabuchi H. Katsura T. Sugihara S. Inflammatory cytokines and enzymes in synovial fluid of patients with rheumatoid arthritis and other arthritides Int Arch Allergy Immunol 98 1992 286 292
    • (1992) Int Arch Allergy Immunol , vol.98 , pp. 286-292
    • Yoshida, K.1    Kobayashi, K.2    Yamagata, N.3    Iwabuchi, H.4    Katsura, T.5    Sugihara, S.6
  • 227
    • 0027193338 scopus 로고
    • Elevated synovial fluid levels of interleukin-6 and tumor necrosis factor associated with early experimental canine osteoarthritis
    • Venn G. Nietfeld J.J. Duits A.J. Brennan F.M. Arner E. Covington M. Elevated synovial fluid levels of interleukin-6 and tumor necrosis factor associated with early experimental canine osteoarthritis Arthritis Rheum 36 1993 819 826
    • (1993) Arthritis Rheum , vol.36 , pp. 819-826
    • Venn, G.1    Nietfeld, J.J.2    Duits, A.J.3    Brennan, F.M.4    Arner, E.5    Covington, M.6
  • 228
  • 229
    • 0025014781 scopus 로고
    • IL-6 production by human articular chondrocytes: modulation of its synthesis by cytokines, growth-factors, and hormones in vitro
    • Guerne P.A. Carson D.A. Lotz M. IL-6 production by human articular chondrocytes: modulation of its synthesis by cytokines, growth-factors, and hormones in vitro J Immunol 144 1990 499 505
    • (1990) J Immunol , vol.144 , pp. 499-505
    • Guerne, P.A.1    Carson, D.A.2    Lotz, M.3
  • 231
    • 0026806180 scopus 로고
    • Effects of interleukin-6 on the metabolism of connective tissue components, in rheumatoid synovial fibroblasts
    • Ito A. Itoh Y. Sasaguri Y. Morimatsu M. Mori Y. Effects of interleukin-6 on the metabolism of connective tissue components, in rheumatoid synovial fibroblasts Arthritis Rheum 35 1992 11197 11201
    • (1992) Arthritis Rheum , vol.35 , pp. 11197-11201
    • Ito, A.1    Itoh, Y.2    Sasaguri, Y.3    Morimatsu, M.4    Mori, Y.5
  • 232
    • 0025176658 scopus 로고
    • Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF
    • Schindler R. Mancilla J. Endres S. Ghorbani G. Clark S. Dinarello C.A. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF Blood 75 1990 40 47
    • (1990) Blood , vol.75 , pp. 40-47
    • Schindler, R.1    Mancilla, J.2    Endres, S.3    Ghorbani, G.4    Clark, S.5    Dinarello, C.A.6
  • 233
    • 0025046995 scopus 로고
    • Interleukin 6 enhances the production of tissue inhibitor of metalloproteinases (TIMP) but not that of matrix metalloproteinases by humanfibroblasts
    • Sato T. Ito A. Mori Y. Interleukin 6 enhances the production of tissue inhibitor of metalloproteinases (TIMP) but not that of matrix metalloproteinases by humanfibroblasts Biochem Biophys Res Commun 170 1990 824 829
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 824-829
    • Sato, T.1    Ito, A.2    Mori, Y.3
  • 234
    • 0026654545 scopus 로고
    • Interleukin-6 (IL-6) in adjuvant arthritis of rats and its pharmacological modulation
    • Theisen-Popp P. Pape H. Muller-Peddinghaus R. Interleukin-6 (IL-6) in adjuvant arthritis of rats and its pharmacological modulation Int J Immunol 14 1992 565 571
    • (1992) Int J Immunol , vol.14 , pp. 565-571
    • Theisen-Popp, P.1    Pape, H.2    Muller-Peddinghaus, R.3
  • 235
    • 0019827942 scopus 로고
    • Na-hyaluronate molecular size variations in equine and human arthritic synovial fluids and the effect on phagocytic cells
    • Balazs E.A. Briller S.O. Denlinger J.L. Na-hyaluronate molecular size variations in equine and human arthritic synovial fluids and the effect on phagocytic cells Semin Arthritis Rheum Suppl 1 1980 141 143
    • (1980) Semin Arthritis Rheum , Issue.Suppl 1 , pp. 141-143
    • Balazs, E.A.1    Briller, S.O.2    Denlinger, J.L.3
  • 236
    • 0024368010 scopus 로고
    • Clinical uses of hyaluronan
    • Balazs E.A. Denlinger J.L. Clinical uses of hyaluronan Evered D. Whelan J. Ciba Foundation Symposium The biology of hyaluronan 1989 Wiley and Sons Chichester 265 280
    • (1989) , pp. 265-280
    • Balazs, E.A.1    Denlinger, J.L.2
  • 237
    • 67649951066 scopus 로고
    • Sodium hyaluronate and joint function
    • Balazs E.A. Denlinger J.L. Sodium hyaluronate and joint function Equine Vet Sci 5 1985 217 228
    • (1985) Equine Vet Sci , vol.5 , pp. 217-228
    • Balazs, E.A.1    Denlinger, J.L.2
  • 238
    • 0028484678 scopus 로고
    • The effect of additive hyaluronic acid on animal joints with experimentally reduced lubricating ability
    • Mabuchi K. Tsukamoto Y. Obara T. Yamaguchi T. The effect of additive hyaluronic acid on animal joints with experimentally reduced lubricating ability J Biomed Mater Ref 28 1994 865 870
    • (1994) J Biomed Mater Ref , vol.28 , pp. 865-870
    • Mabuchi, K.1    Tsukamoto, Y.2    Obara, T.3    Yamaguchi, T.4
  • 239
    • 0023176457 scopus 로고
    • The role of hyaluronic acid in joint stability: a hypothesis for hip displasia and allied disorders
    • Cullis-Hill D. Ghosh P. The role of hyaluronic acid in joint stability: a hypothesis for hip displasia and allied disorders Med Hypothesis 23 1986 171 185
    • (1986) Med Hypothesis , vol.23 , pp. 171-185
    • Cullis-Hill, D.1    Ghosh, P.2
  • 241
    • 0031171471 scopus 로고    scopus 로고
    • Increased friction of animal joints by experimental degeneration and recovery by addition of hyaluronic acid
    • Obara T. Mabuchi K. Iso T. Yamaguchi T. Increased friction of animal joints by experimental degeneration and recovery by addition of hyaluronic acid Clin Biomech 12 1997 246 252
    • (1997) Clin Biomech , vol.12 , pp. 246-252
    • Obara, T.1    Mabuchi, K.2    Iso, T.3    Yamaguchi, T.4
  • 242
    • 0027489767 scopus 로고
    • Intraarticular hyaluronan injections in the treatment of osteoarthritis. State-of-the-art review
    • Peyron J.G. Intraarticular hyaluronan injections in the treatment of osteoarthritis. State-of-the-art review J Rheumatol 20 1993 10 15
    • (1993) J Rheumatol , vol.20 , pp. 10-15
    • Peyron, J.G.1
  • 243
    • 0022343146 scopus 로고
    • Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies
    • Dahl L.B. Dahl I.M.S. Engstrom-Laurent A. Granath K. Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies Ann Rheum Dis 44 1985 817 822
    • (1985) Ann Rheum Dis , vol.44 , pp. 817-822
    • Dahl, L.B.1    Dahl, I.M.S.2    Engstrom-Laurent, A.3    Granath, K.4
  • 244
    • 0027157702 scopus 로고
    • Osteoarthritis and hyaluronan: palliative or disease modifying treatment?
    • Ghosh P. Osteoarthritis and hyaluronan: palliative or disease modifying treatment? Semin Arthritis Rheum 22 1993 1 3
    • (1993) Semin Arthritis Rheum , vol.22 , pp. 1-3
    • Ghosh, P.1
  • 245
    • 0028140252 scopus 로고
    • The role of hyaluronic acid (hyaluronan) in health and disease: interactions with cells, cartilage and components of synovial fluid
    • Ghosh P. The role of hyaluronic acid (hyaluronan) in health and disease: interactions with cells, cartilage and components of synovial fluid Clin Exp Rheumatol 12 1994 75 82
    • (1994) Clin Exp Rheumatol , vol.12 , pp. 75-82
    • Ghosh, P.1
  • 246
    • 0027943865 scopus 로고
    • Interaction of hyaluronan (hyaluronic acid) with phospholipids as determined by gel permeation chromatography, multi-angle laser-lightscattering photometry and 1H-NMR spectroscopy
    • Ghosh P. Hutadilok N. Adam N. Lentini A. Interaction of hyaluronan (hyaluronic acid) with phospholipids as determined by gel permeation chromatography, multi-angle laser-lightscattering photometry and 1H-NMR spectroscopy Int J Biol Macromol 16 1994 237 244
    • (1994) Int J Biol Macromol , vol.16 , pp. 237-244
    • Ghosh, P.1    Hutadilok, N.2    Adam, N.3    Lentini, A.4
  • 247
    • 0026446637 scopus 로고
    • CD44: the hyaluronan receptor
    • Underhill C. CD44: the hyaluronan receptor J Cell Sci 103 1992 293 298
    • (1992) J Cell Sci , vol.103 , pp. 293-298
    • Underhill, C.1
  • 248
    • 0028116787 scopus 로고
    • Hyaluronan receptor (CD44) expression and function in human peripheral blood monocytes and alveolar macrophages
    • Culty M. O'Mara T.E. Underhill C.B. Yeager H. Jr Swartz R.P. Hyaluronan receptor (CD44) expression and function in human peripheral blood monocytes and alveolar macrophages J Leukoc Biol 56 1994 605 611
    • (1994) J Leukoc Biol , vol.56 , pp. 605-611
    • Culty, M.1    O'Mara, T.E.2    Underhill, C.B.3    Yeager, H.4    Swartz, R.P.5
  • 249
    • 0025641883 scopus 로고
    • The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell-surface glycoproteins
    • Culty M. Miyake K. Kincade P.W. Silorski E. Butcher E.C. Underhill C. The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell-surface glycoproteins J Cell Biol 111 1990 2765 2774
    • (1990) J Cell Biol , vol.111 , pp. 2765-2774
    • Culty, M.1    Miyake, K.2    Kincade, P.W.3    Silorski, E.4    Butcher, E.C.5    Underhill, C.6
  • 251
    • 0027491281 scopus 로고
    • Internalization of hyaluronan by chondrocytes occurs via receptor mediated endocytosis
    • Hua Q. Knudson C.B. Knudson W. Internalization of hyaluronan by chondrocytes occurs via receptor mediated endocytosis J Cell Sci 106 1993 365 375
    • (1993) J Cell Sci , vol.106 , pp. 365-375
    • Hua, Q.1    Knudson, C.B.2    Knudson, W.3
  • 252
    • 0019829102 scopus 로고
    • The biochemistry of the human synovial lining with special reference to alterations in metabolism in rheumatoid arthritis
    • Henderson B. The biochemistry of the human synovial lining with special reference to alterations in metabolism in rheumatoid arthritis Pathol Res Pract 172 1981 1 24
    • (1981) Pathol Res Pract , vol.172 , pp. 1-24
    • Henderson, B.1
  • 253
    • 85119815381 scopus 로고
    • Function of synovial lining
    • Henderson B. Edwards J.C.W. Function of synovial lining The synovial lining in health and disease 1987 Chapman and Hall London 41 74
    • (1987) , pp. 41-74
    • Henderson, B.1    Edwards, J.C.W.2
  • 254
    • 0023229488 scopus 로고
    • The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment
    • Smith M.M. Ghosh P. The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment Rheumatol Int 7 1987 113 122
    • (1987) Rheumatol Int , vol.7 , pp. 113-122
    • Smith, M.M.1    Ghosh, P.2
  • 255
    • 0028919112 scopus 로고
    • Synovial intimal fibroblasts
    • Edwards J.C.W. Synovial intimal fibroblasts Ann Rheum Dis 54 1995 395 397
    • (1995) Ann Rheum Dis , vol.54 , pp. 395-397
    • Edwards, J.C.W.1
  • 256
    • 0020434232 scopus 로고
    • Synthesis of underpolymerised hyaluronic acid by fibroblasts cultured from rheumatoid and non-rheumatoid synovitis
    • Vuorio E. Einola S. Hakkarainen S. Penttinen R. Synthesis of underpolymerised hyaluronic acid by fibroblasts cultured from rheumatoid and non-rheumatoid synovitis Rheumatol Int 2 1982 97 102
    • (1982) Rheumatol Int , vol.2 , pp. 97-102
    • Vuorio, E.1    Einola, S.2    Hakkarainen, S.3    Penttinen, R.4
  • 257
    • 0007680677 scopus 로고
    • Pentosan polysulphate stimulates hyaluronate and DNA synthesis in synovial fibroblasts and partially reduces the suppressive effect of hydrocortisone on fibroblast metabolism
    • Hutadilok N. Smith M. Cullis-Hill D. Ghosh P. Pentosan polysulphate stimulates hyaluronate and DNA synthesis in synovial fibroblasts and partially reduces the suppressive effect of hydrocortisone on fibroblast metabolism Curr Ther Res 44 1988 845 860
    • (1988) Curr Ther Res , vol.44 , pp. 845-860
    • Hutadilok, N.1    Smith, M.2    Cullis-Hill, D.3    Ghosh, P.4
  • 258
    • 0027248696 scopus 로고
    • Pentosan polysulphate and glycosaminoglycan polysulphate stimulate the synthesis of hyaluronan in vivo
    • Francis D.J. Hutadilok N. Kongtawelert P. Ghosh P. Pentosan polysulphate and glycosaminoglycan polysulphate stimulate the synthesis of hyaluronan in vivo Rheumatol Int 13 1993 61 64
    • (1993) Rheumatol Int , vol.13 , pp. 61-64
    • Francis, D.J.1    Hutadilok, N.2    Kongtawelert, P.3    Ghosh, P.4
  • 259
    • 0026574141 scopus 로고
    • Intea-articular injection of pentosanpolysulphate results in increased hyaluronan molecular weight in joint fluid
    • Verbruggen G. Veys E.M. Intea-articular injection of pentosanpolysulphate results in increased hyaluronan molecular weight in joint fluid Clin Exp Rheumatol 10 1992 249 254
    • (1992) Clin Exp Rheumatol , vol.10 , pp. 249-254
    • Verbruggen, G.1    Veys, E.M.2
  • 260
    • 0004732664 scopus 로고    scopus 로고
    • The effects of intra-articular pentosan polysulphate (Cartrophen) on synovial fluid visco-elasticity and hyaluronan molecular weight in patients with gonarthritis
    • Adam N. Ghosh P. Swain M. Rasaratnam I. Ryan P. The effects of intra-articular pentosan polysulphate (Cartrophen) on synovial fluid visco-elasticity and hyaluronan molecular weight in patients with gonarthritis Osteoarthritis Cart 4 1996 viii
    • (1996) Osteoarthritis Cart , vol.4 , pp. viii
    • Adam, N.1    Ghosh, P.2    Swain, M.3    Rasaratnam, I.4    Ryan, P.5
  • 261
    • 0029870541 scopus 로고    scopus 로고
    • Interactions of pentosan polysulfate with cartilage matrix proteins and synovial fibroblasts derived from patients with osteoarthritis
    • Ghosh P. Hutadilok N. Interactions of pentosan polysulfate with cartilage matrix proteins and synovial fibroblasts derived from patients with osteoarthritis Osteoarthritis Cart 4 1996 43 53
    • (1996) Osteoarthritis Cart , vol.4 , pp. 43-53
    • Ghosh, P.1    Hutadilok, N.2
  • 262
    • 4243657548 scopus 로고
    • Calcium pentosan polysulfate given orally to rabbits with inflamed knee joints abrogates interleukin-l-induced antiproliferative effects and reduces nitric oxide but not interleukin-6 activity in ex vivo cultures of synovial fibroblasts
    • Smith M.M Numata Y. Bowman L. Ghosh P. Calcium pentosan polysulfate given orally to rabbits with inflamed knee joints abrogates interleukin-l-induced antiproliferative effects and reduces nitric oxide but not interleukin-6 activity in ex vivo cultures of synovial fibroblasts Arthritis Rheum 38 1995 1312
    • (1995) Arthritis Rheum , vol.38 , pp. 1312
    • Smith, M.M1    Numata, Y.2    Bowman, L.3    Ghosh, P.4
  • 263
    • 84924833491 scopus 로고
    • Osteoarthritis of the hip: a study of the nature and evolution of the disease
    • Harrison M.H.M. Schajowicz F. Trueta J. Osteoarthritis of the hip: a study of the nature and evolution of the disease J Bone Joint Surg Br 35 1953 598 626
    • (1953) J Bone Joint Surg Br , vol.35 , pp. 598-626
    • Harrison, M.H.M.1    Schajowicz, F.2    Trueta, J.3
  • 264
    • 0028486868 scopus 로고
    • Vascular aspects of degenerative joint disorders
    • Arnoldi C.C. Vascular aspects of degenerative joint disorders Acta Orthop Scand 65 1994 1 82
    • (1994) Acta Orthop Scand , vol.65 , pp. 1-82
    • Arnoldi, C.C.1
  • 267
    • 0019994333 scopus 로고
    • Intraosseous pressure in the patella in relation to simulated joint effusion and knee position
    • Bunger C. Harving S. Bunger E.H. Intraosseous pressure in the patella in relation to simulated joint effusion and knee position Acta Orthop Scand 53 1982 745 751
    • (1982) Acta Orthop Scand , vol.53 , pp. 745-751
    • Bunger, C.1    Harving, S.2    Bunger, E.H.3
  • 268
    • 0003541443 scopus 로고
    • The blood supply to bone
    • Brookes M. The blood supply to bone 1971 Butterworths London 234 302
    • (1971) , pp. 234-302
    • Brookes, M.1
  • 270
    • 0015381468 scopus 로고
    • Venous engorgement and intraosseous hypertension in osteoarthritis of the hip
    • Arnoldi C.C. Linderholm H. Mussbichler H. Venous engorgement and intraosseous hypertension in osteoarthritis of the hip J Bone Joint Surg Br 54 1972 409 421
    • (1972) J Bone Joint Surg Br , vol.54 , pp. 409-421
    • Arnoldi, C.C.1    Linderholm, H.2    Mussbichler, H.3
  • 271
    • 0024360381 scopus 로고
    • Intraosseous pressure and partial pressures of oxygen and carbon dioxide in osteoarthritis
    • Kiaer T. Grønlund J. Sørensen K.H. Intraosseous pressure and partial pressures of oxygen and carbon dioxide in osteoarthritis Semin Arthritis Rheum 18 1989 57 60
    • (1989) Semin Arthritis Rheum , vol.18 , pp. 57-60
    • Kiaer, T.1    Grønlund, J.2    Sørensen, K.H.3
  • 272
    • 0028946487 scopus 로고
    • Microvascular obstruction in avascular necrosis: inmiunobistochemistry of 14 femoral heads
    • Starklint H. Lausten G.S. Arnoldi C.C. Microvascular obstruction in avascular necrosis: inmiunobistochemistry of 14 femoral heads Acta Orthop Scand 66 1995 9 12
    • (1995) Acta Orthop Scand , vol.66 , pp. 9-12
    • Starklint, H.1    Lausten, G.S.2    Arnoldi, C.C.3
  • 273
    • 0013978526 scopus 로고
    • The vascular factor in osteoarthritis
    • Brookes M. The vascular factor in osteoarthritis Surg Gynecol Obstet 123 1966 1255 1260
    • (1966) Surg Gynecol Obstet , vol.123 , pp. 1255-1260
    • Brookes, M.1
  • 275
    • 0022871803 scopus 로고
    • Advances in clinical fibrinolysis
    • Hessel L.W. Kluft C. Advances in clinical fibrinolysis Clin Haematol 15 1986 443 463
    • (1986) Clin Haematol , vol.15 , pp. 443-463
    • Hessel, L.W.1    Kluft, C.2
  • 276
    • 0028814602 scopus 로고
    • Fibrin enhances the expression of IL-1 beta by human peripheral blood mononuclear cells: implications in pulmonary inflammation
    • Perez R.L. Roman J. Fibrin enhances the expression of IL-1 beta by human peripheral blood mononuclear cells: implications in pulmonary inflammation J Immunol 154 1995 1879 1887
    • (1995) J Immunol , vol.154 , pp. 1879-1887
    • Perez, R.L.1    Roman, J.2
  • 277
    • 0019460841 scopus 로고
    • A mechanism of migration inhibition in delayed-type hypersensitivity reactions
    • Hopper K.E. Geczy C.L. Davies W.A. A mechanism of migration inhibition in delayed-type hypersensitivity reactions J Immunol 126 1981 1052 1058
    • (1981) J Immunol , vol.126 , pp. 1052-1058
    • Hopper, K.E.1    Geczy, C.L.2    Davies, W.A.3
  • 280
    • 0029336629 scopus 로고
    • Inflammation: they're not just for clots anymore
    • Esmon C.T. Inflammation: they're not just for clots anymore Curr Biol 5 1995 743 746
    • (1995) Curr Biol , vol.5 , pp. 743-746
    • Esmon, C.T.1
  • 281
    • 0019135515 scopus 로고
    • The synovial membrane in human coxarthrosis: light and electron microscopic studies
    • Arnoldi C.C. Reimann I. Bretlau P. The synovial membrane in human coxarthrosis: light and electron microscopic studies Clin Orthop 148 1980
    • (1980) Clin Orthop , vol.148
    • Arnoldi, C.C.1    Reimann, I.2    Bretlau, P.3
  • 282
    • 85119789983 scopus 로고
    • Effect of pentosan-polysulfate on the haemorheological parameters in elderly patients: possible role of leucocyte arachidonic acid metabolism
    • Freyburger G. Larrue F. Larrue J. Manciet G. Roudaut M.F. Boisseau M.R. Effect of pentosan-polysulfate on the haemorheological parameters in elderly patients: possible role of leucocyte arachidonic acid metabolism Thromb Res Suppl VI 1986 46
    • (1986) Thromb Res , Issue.Suppl VI , pp. 46
    • Freyburger, G.1    Larrue, F.2    Larrue, J.3    Manciet, G.4    Roudaut, M.F.5    Boisseau, M.R.6
  • 283
    • 0023571304 scopus 로고
    • Hemorheological changes in elderly subjects: effect of pentosan polysulfate and possible role of leucocyte arachidonic acid metabolism
    • Freyburger G. Larrue F. Manciet G. Lorient-Roudaut M.F. Larrue J. Boisseau M.R. Hemorheological changes in elderly subjects: effect of pentosan polysulfate and possible role of leucocyte arachidonic acid metabolism Thromb Haemost 57 1987 322 325
    • (1987) Thromb Haemost , vol.57 , pp. 322-325
    • Freyburger, G.1    Larrue, F.2    Manciet, G.3    Lorient-Roudaut, M.F.4    Larrue, J.5    Boisseau, M.R.6
  • 284
    • 0007106221 scopus 로고
    • Untersuchungen von Patienten mit zerebraler Ischärnie unter Peutosanpolysulphat (SP54)
    • Szirmai I. Kamondi A. Magyar H. JuhAsz C. Untersuchungen von Patienten mit zerebraler Ischärnie unter Peutosanpolysulphat (SP54) Investigations in patients with cerebral ischemia treated with pentosan polysulfate (SP54) Perfusion 6 1993 314 320
    • (1993) Perfusion , vol.6 , pp. 314-320
    • Szirmai, I.1    Kamondi, A.2    Magyar, H.3    JuhAsz, C.4
  • 285
    • 0023660011 scopus 로고
    • Prevention of recurrence of cerebrovascular thromboses: a randomized comparative study of acetylsalicylic acid and sodium pentosan polysulfate
    • Vinazzer H. Prevention of recurrence of cerebrovascular thromboses: a randomized comparative study of acetylsalicylic acid and sodium pentosan polysulfate Fortschr Med 105 1987 79 83
    • (1987) Fortschr Med , vol.105 , pp. 79-83
    • Vinazzer, H.1
  • 286
    • 0023682168 scopus 로고
    • Effects of various doses of SP54 on fibrinolytic activity in patients with thrombotic diseases
    • Losonczy H. Nagy I. Dávid M. Effects of various doses of SP54 on fibrinolytic activity in patients with thrombotic diseases Folia Haematol Leipzig 115 1988 388 393
    • (1988) Folia Haematol Leipzig , vol.115 , pp. 388-393
    • Losonczy, H.1    Nagy, I.2    Dávid, M.3
  • 287
    • 0026352060 scopus 로고
    • Effect of pentosan polysulfate on activated partial thromboplastin time, thrombin time, euglobulin clot lysis, and on tissue-type plasminogenactivator and plasminogen activator inhibitor activities in patients with thromboembolic disease
    • Losonczy H. Dávid M. Nagy I. Effect of pentosan polysulfate on activated partial thromboplastin time, thrombin time, euglobulin clot lysis, and on tissue-type plasminogenactivator and plasminogen activator inhibitor activities in patients with thromboembolic disease Semin Thromb Hemost 17 1991 394 398
    • (1991) Semin Thromb Hemost , vol.17 , pp. 394-398
    • Losonczy, H.1    Dávid, M.2    Nagy, I.3
  • 288
    • 0026043109 scopus 로고
    • Comparison of the effects of sodium pentosanpolysulfate and unfractionated heparin on venous thrombosis: an experimental study in rats
    • Kiesel J. Harbauer G. Wenzel E. Pindur G. Bohnerth S. Comparison of the effects of sodium pentosanpolysulfate and unfractionated heparin on venous thrombosis: an experimental study in rats Thromb Res 64 1991 301 308
    • (1991) Thromb Res , vol.64 , pp. 301-308
    • Kiesel, J.1    Harbauer, G.2    Wenzel, E.3    Pindur, G.4    Bohnerth, S.5
  • 289
    • 85119800465 scopus 로고
    • Pentosanpolysulfat bei peripherer arterieller Verschlußkrankheit im Stadium II nach Fontaine. Randomisierte, plazebo-kontrollierte DoppelblindStudie mit Cross-over
    • Kollár L. Rozsos I. István M. Kiss T. Pentosanpolysulfat bei peripherer arterieller Verschlußkrankheit im Stadium II nach Fontaine. Randomisierte, plazebo-kontrollierte DoppelblindStudie mit Cross-over Perfusion 2 1989 52 56
    • (1989) Perfusion , vol.2 , pp. 52-56
    • Kollár, L.1    Rozsos, I.2    István, M.3    Kiss, T.4
  • 291
    • 0030760170 scopus 로고    scopus 로고
    • Platelets and inflammation
    • Klinger M.H.F. Platelets and inflammation Anat Embryol 196 1997 1 11
    • (1997) Anat Embryol , vol.196 , pp. 1-11
    • Klinger, M.H.F.1
  • 292
    • 0025826664 scopus 로고
    • Interaction of heparinoids with platelets: comparison with heparin and low molecular weight heparins
    • Messmore H.L. Griffin B. Koza M. Seghatchian J. Fareed J. Coyne E. Interaction of heparinoids with platelets: comparison with heparin and low molecular weight heparins Semin Thromb Hemost 17 1991 57 59
    • (1991) Semin Thromb Hemost , vol.17 , pp. 57-59
    • Messmore, H.L.1    Griffin, B.2    Koza, M.3    Seghatchian, J.4    Fareed, J.5    Coyne, E.6
  • 293
    • 0024360749 scopus 로고
    • In vitro studies of the interaction of heparin, low molecular weight heparin and heparinoids with platelets
    • Messmore H.L. Jr Griffin B. Fareed J. Coyne E. Seghatchian J. In vitro studies of the interaction of heparin, low molecular weight heparin and heparinoids with platelets Ann NYAcad Sci 556 1989 217 232
    • (1989) Ann NYAcad Sci , vol.556 , pp. 217-232
    • Messmore, H.L.1    Griffin, B.2    Fareed, J.3    Coyne, E.4    Seghatchian, J.5
  • 294
    • 0015329819 scopus 로고
    • Action on fibrinolysis and platelet aggregation of a synthetic, heparin-like sulfated polyanion (SP 54) given orally and parenterally, as relatedto lipidic fractions: trials on long-term prophylactic treatment under double-blind conditions
    • Frandoli G. Spreafico P.L. Lampugnani P. Tammaro A.E. Action on fibrinolysis and platelet aggregation of a synthetic, heparin-like sulfated polyanion (SP 54) given orally and parenterally, as relatedto lipidic fractions: trials on long-term prophylactic treatment under double-blind conditions Arzneimittelforschung 22 1972 759 763
    • (1972) Arzneimittelforschung , vol.22 , pp. 759-763
    • Frandoli, G.1    Spreafico, P.L.2    Lampugnani, P.3    Tammaro, A.E.4
  • 295
    • 0015598277 scopus 로고
    • The preventative effect of a low-molecular weight pentosan-polysulphate on DAS-induced increase in pulmonary vascular resistance caused by platelet-aggregation
    • Schumacher K.A. Classen H.G. The preventative effect of a low-molecular weight pentosan-polysulphate on DAS-induced increase in pulmonary vascular resistance caused by platelet-aggregation Arzeimittelforschung 23 1973 431 433
    • (1973) Arzeimittelforschung , vol.23 , pp. 431-433
    • Schumacher, K.A.1    Classen, H.G.2
  • 296
    • 0019160482 scopus 로고
    • Influence on the clotting mechanism of sodium pentosan polysulfate (SP54) in comparison to commercial beef lung sodium heparin
    • Vinazzer H. Haas S. Stemberger A. Influence on the clotting mechanism of sodium pentosan polysulfate (SP54) in comparison to commercial beef lung sodium heparin Thromb Res 20 1980 57 68
    • (1980) Thromb Res , vol.20 , pp. 57-68
    • Vinazzer, H.1    Haas, S.2    Stemberger, A.3
  • 297
    • 0020662203 scopus 로고
    • Fibrinogen binding on human platelets: influence of different heparins and of pentosane polysulfate
    • Dunn F. Soria J. Soria C. Thomaidis A. Tobelem G. Caen J.P. Fibrinogen binding on human platelets: influence of different heparins and of pentosane polysulfate Thromb Res 29 1983 141 148
    • (1983) Thromb Res , vol.29 , pp. 141-148
    • Dunn, F.1    Soria, J.2    Soria, C.3    Thomaidis, A.4    Tobelem, G.5    Caen, J.P.6
  • 298
    • 0018637344 scopus 로고
    • Effects of a sulphated xylan on aggregation of human blood platelets
    • Kindness G. Williamson F.B. Long W.F. Effects of a sulphated xylan on aggregation of human blood platelets Thromb Res 16 1979 97 105
    • (1979) Thromb Res , vol.16 , pp. 97-105
    • Kindness, G.1    Williamson, F.B.2    Long, W.F.3
  • 299
    • 10844243765 scopus 로고    scopus 로고
    • Role of hyperlipidemia, hypercoagulability and hypofibrinolysis in osteoarthritis: results of pentosan polysulphate treated osteoarthritic dogs
    • Cheras P.A. Nielsen G.V.L. Blackwell E.A. Whitaker A.N. Peacock K.A. Smith K.R. Role of hyperlipidemia, hypercoagulability and hypofibrinolysis in osteoarthritis: results of pentosan polysulphate treated osteoarthritic dogs Osteoarthritis Cartilage 5 1997 38
    • (1997) Osteoarthritis Cartilage , vol.5 , pp. 38
    • Cheras, P.A.1    Nielsen, G.V.L.2    Blackwell, E.A.3    Whitaker, A.N.4    Peacock, K.A.5    Smith, K.R.6
  • 300
    • 0019176563 scopus 로고
    • Anticoagulant activities of a pentosane polysulphate: comparison with standard heparin and a fraction of low molecular weight heparin
    • Soria C. Soria J. Ryckewaert J.J. Holmer E. Caen J.P. Anticoagulant activities of a pentosane polysulphate: comparison with standard heparin and a fraction of low molecular weight heparin Thromb Res 19 1980 455 463
    • (1980) Thromb Res , vol.19 , pp. 455-463
    • Soria, C.1    Soria, J.2    Ryckewaert, J.J.3    Holmer, E.4    Caen, J.P.5
  • 301
    • 0018842350 scopus 로고
    • The effect of a sulfated polysaccharide on antithrombin III
    • Czapek E.E. Kwaan H.C. Szczecinski M. The effect of a sulfated polysaccharide on antithrombin III J Lab Clin Med 95 1980 783 790
    • (1980) J Lab Clin Med , vol.95 , pp. 783-790
    • Czapek, E.E.1    Kwaan, H.C.2    Szczecinski, M.3
  • 302
    • 0029006198 scopus 로고
    • Effect of sulfated xylans during the interaction of [125I]-thrombin with antithrombin III or heparin cofactor II of human plasma
    • 125I]-thrombin with antithrombin III or heparin cofactor II of human plasma Eur J Drug Metab Pharmacokinet 20 1995 73 77
    • (1995) Eur J Drug Metab Pharmacokinet , vol.20 , pp. 73-77
    • Simmons, R.B.1    Newton, G.R.2    Doctor, V.M.3
  • 304
    • 0019845489 scopus 로고
    • Studies on the different mechanisms by which heparin and polysulphated xylan (PZ 68) inhibit blood coagulation in man
    • Ryde M. Eriksson H. Tangen O. Studies on the different mechanisms by which heparin and polysulphated xylan (PZ 68) inhibit blood coagulation in man Thromb Res 23 1981 435 445
    • (1981) Thromb Res , vol.23 , pp. 435-445
    • Ryde, M.1    Eriksson, H.2    Tangen, O.3
  • 305
    • 0022624465 scopus 로고
    • Pentosan polysulphate: activation of heparin cofactor II or antithrombin III according to molecular weight fractionation
    • Scully M.F. Ellis V. Kakkar V.V. Pentosan polysulphate: activation of heparin cofactor II or antithrombin III according to molecular weight fractionation Thromb Res 41 1986 489 499
    • (1986) Thromb Res , vol.41 , pp. 489-499
    • Scully, M.F.1    Ellis, V.2    Kakkar, V.V.3
  • 306
    • 0021333908 scopus 로고
    • The antiheparin effect of a heparinoid, pentosan polysulphate: investigation of a mechanism
    • Scully M.F Kakkar V.V. The antiheparin effect of a heparinoid, pentosan polysulphate: investigation of a mechanism Biochem J 218 1984 657 665
    • (1984) Biochem J , vol.218 , pp. 657-665
    • Scully, M.F1    Kakkar, V.V.2
  • 307
    • 0021208144 scopus 로고
    • Identification of heparin cofactor II as the principal plasma cofactor for the antithrombin activity of pentosan polysulphate (SP54)
    • Scully M.F Kakkar V.V. Identification of heparin cofactor II as the principal plasma cofactor for the antithrombin activity of pentosan polysulphate (SP54) Thromb Res 36 1984 187 194
    • (1984) Thromb Res , vol.36 , pp. 187-194
    • Scully, M.F1    Kakkar, V.V.2
  • 308
    • 0026777310 scopus 로고
    • Kinetic considerations on the physiologic control of thrombin and Factor Xa
    • Scully M.R. Kinetic considerations on the physiologic control of thrombin and Factor Xa Semin Thromb Hemost 18 1992 218 223
    • (1992) Semin Thromb Hemost , vol.18 , pp. 218-223
    • Scully, M.R.1
  • 309
    • 0023722879 scopus 로고
    • Further studies on the mechanisms for the antithrombotic effects of sulfated polysaccharides in rabbit
    • Ofosu F.A. Fernandez F. Anvari N. Caranobe C. Dol F. Cadroy Y. Further studies on the mechanisms for the antithrombotic effects of sulfated polysaccharides in rabbit Thromb Haemost 60 1988 188 192
    • (1988) Thromb Haemost , vol.60 , pp. 188-192
    • Ofosu, F.A.1    Fernandez, F.2    Anvari, N.3    Caranobe, C.4    Dol, F.5    Cadroy, Y.6
  • 310
    • 0022924107 scopus 로고
    • Mechanisms for inhibition of the generation of thrombin activity by sulfated polysaccharides
    • Ofosu F.A. Modi G.J. Hirsh J. Buchanan M.R. Blajchman M.A. Mechanisms for inhibition of the generation of thrombin activity by sulfated polysaccharides Ann NY Acad Sci 485 1986 41 55
    • (1986) Ann NY Acad Sci , vol.485 , pp. 41-55
    • Ofosu, F.A.1    Modi, G.J.2    Hirsh, J.3    Buchanan, M.R.4    Blajchman, M.A.5
  • 312
    • 0021637882 scopus 로고
    • Inhibition of thrombin-induced platelet aggregation and serotonin release by antithrombin III and heparin co-factor II in the presence of standard heparin, dermatan sulfate and pentosan polysulfate
    • Sie P. Fernandez F. Caranobe C. Gabaig A.M. Boneu B. Inhibition of thrombin-induced platelet aggregation and serotonin release by antithrombin III and heparin co-factor II in the presence of standard heparin, dermatan sulfate and pentosan polysulfate Thromb Res 35 1984 231 236
    • (1984) Thromb Res , vol.35 , pp. 231-236
    • Sie, P.1    Fernandez, F.2    Caranobe, C.3    Gabaig, A.M.4    Boneu, B.5
  • 313
    • 85119814965 scopus 로고
    • The relative importance of anti-thrombin II for the anticoagulant effect of heparin, dermatan sulfate (DS) and pentosan polysulfate (PPS)
    • Sie P. Fernandez F. Ofosu F. The relative importance of anti-thrombin II for the anticoagulant effect of heparin, dermatan sulfate (DS) and pentosan polysulfate (PPS) Thromb Haemost 54 1985 204
    • (1985) Thromb Haemost , vol.54 , pp. 204
    • Sie, P.1    Fernandez, F.2    Ofosu, F.3
  • 314
    • 0022920122 scopus 로고
    • Respective role of antithrombin III and heparin cofactor II in the in vitro anticoagulant effect of heparin and of various sulphated polysaccharides
    • Sie P. Ofosu F. Fernandez F. Buchanan M.R. Petitou M. Boner B. Respective role of antithrombin III and heparin cofactor II in the in vitro anticoagulant effect of heparin and of various sulphated polysaccharides Br J Haematol 64 1986 707 714
    • (1986) Br J Haematol , vol.64 , pp. 707-714
    • Sie, P.1    Ofosu, F.2    Fernandez, F.3    Buchanan, M.R.4    Petitou, M.5    Boner, B.6
  • 315
    • 0026314784 scopus 로고
    • Effect of pentosan polysulphate on fibrinolysis: basic tests and clinical application
    • Vinazzer H. Effect of pentosan polysulphate on fibrinolysis: basic tests and clinical application Semin Thromb Hemost 17 1991 375 378
    • (1991) Semin Thromb Hemost , vol.17 , pp. 375-378
    • Vinazzer, H.1
  • 316
    • 0022549078 scopus 로고
    • Klinische untersuchungen zur fibrinolytischen wirkung von pentosanpolysulfat
    • Vinazzer H. Klinische untersuchungen zur fibrinolytischen wirkung von pentosanpolysulfat Folia Haematol 113 1986 272 277
    • (1986) Folia Haematol , vol.113 , pp. 272-277
    • Vinazzer, H.1
  • 317
    • 0020049880 scopus 로고
    • A comparison of pentosan polysulphate (SP54) and heparin I mechanism of action on blood coagulation
    • Fischer A-M. Barrowcliffe T.W. Thomas D.P. A comparison of pentosan polysulphate (SP54) and heparin I mechanism of action on blood coagulation Thromb Haemostas 47 1982 104 108
    • (1982) Thromb Haemostas , vol.47 , pp. 104-108
    • Fischer, A-M.1    Barrowcliffe, T.W.2    Thomas, D.P.3
  • 318
    • 0021923416 scopus 로고
    • Comparison between the effect of pentosan polysulphate heparin and antithrombin III injections in antithrombin III deficient patients
    • Fischer A.M Dautzenberg M.D. Aurousseau M.H. Bëguin S. Goudeman J. Hemker H.C. Comparison between the effect of pentosan polysulphate heparin and antithrombin III injections in antithrombin III deficient patients Thromb Res 37 1985 295 307
    • (1985) Thromb Res , vol.37 , pp. 295-307
    • Fischer, A.M1    Dautzenberg, M.D.2    Aurousseau, M.H.3    Bëguin, S.4    Goudeman, J.5    Hemker, H.C.6
  • 319
    • 85119799199 scopus 로고
    • Effect of sulfate xylans during the interaction if 125I thrombin with andthrombin-III or heparin-cofactor-II of human plasma
    • 125I thrombin with andthrombin-III or heparin-cofactor-II of human plasma Eur J Drug 20 1995 162
    • (1995) Eur J Drug , vol.20 , pp. 162
    • Simmons, R.B.1    Newton, G.R.2    Doctor, V.M.3
  • 320
    • 85119813404 scopus 로고
    • Pentosan polysulfate (SP54): mechanism of action on blood coagulation and fibrinolysis after intravenous injection of four different concentrationsin healthy volunteers
    • Sampol J. Angles-Cano E. Benchimol P. Diner H. Boutiere B. Sultan Y. Pentosan polysulfate (SP54): mechanism of action on blood coagulation and fibrinolysis after intravenous injection of four different concentrationsin healthy volunteers Progress in Fibrinolysis VII 1985 316 318
    • (1985) Progress in Fibrinolysis , vol.VII , pp. 316-318
    • Sampol, J.1    Angles-Cano, E.2    Benchimol, P.3    Diner, H.4    Boutiere, B.5    Sultan, Y.6
  • 321
    • 0023244130 scopus 로고
    • The inhibition of thrombindependent positive feedback reactions is critical to the expression of the anticoagulant effect of heparin
    • Ofosu F.A. Sie P. Modi G.J. Fernandez F.A. Buchanan M.R. Blajchman M.A. The inhibition of thrombindependent positive feedback reactions is critical to the expression of the anticoagulant effect of heparin Biochem J 243 1987 579 588
    • (1987) Biochem J , vol.243 , pp. 579-588
    • Ofosu, F.A.1    Sie, P.2    Modi, G.J.3    Fernandez, F.A.4    Buchanan, M.R.5    Blajchman, M.A.6
  • 322
    • 0025612326 scopus 로고
    • Inhibition of coagulation and platelet-adhesion to extracellularmatrix by unfractionated heparin and a low-molecular-weight heparin
    • Krupinsk K. Basicmic M. Lindhoff R. Breddin H.K. Inhibition of coagulation and platelet-adhesion to extracellularmatrix by unfractionated heparin and a low-molecular-weight heparin Blot 61 1990 289 294
    • (1990) Blot , vol.61 , pp. 289-294
    • Krupinsk, K.1    Basicmic, M.2    Lindhoff, R.3    Breddin, H.K.4
  • 323
    • 16044373947 scopus 로고
    • Aktivierung der Fibrinolyse and Thrombolyse durch Polysaccharidschwefelsäureester (Heparin, Heparinoide)
    • Halse T. Aktivierung der Fibrinolyse and Thrombolyse durch Polysaccharidschwefelsäureester (Heparin, Heparinoide) Arzneimittelforschung 12 1962 574 582
    • (1962) Arzneimittelforschung , vol.12 , pp. 574-582
    • Halse, T.1
  • 324
    • 0015936060 scopus 로고
    • Einfluss von oral and transkuten appliziertem SP54 auf präformierte Thrombose im Tierversuch
    • Köstering H. König F. Weber S. Warmarm E. Guerrero M. Einfluss von oral and transkuten appliziertem SP54 auf präformierte Thrombose im Tierversuch Med Welt 24 1973 139 140
    • (1973) Med Welt , vol.24 , pp. 139-140
    • Köstering, H.1    König, F.2    Weber, S.3    Warmarm, E.4    Guerrero, M.5
  • 325
    • 0019983674 scopus 로고
    • Influence of heparin: of different heparin fractions and of a low molecular weight heparin-like substance on the mechanism of fibrinolysis
    • Vinazzer H. Stemberger A. Haas S. Blümel G. Influence of heparin: of different heparin fractions and of a low molecular weight heparin-like substance on the mechanism of fibrinolysis Thromb Res 27 1982 341 352
    • (1982) Thromb Res , vol.27 , pp. 341-352
    • Vinazzer, H.1    Stemberger, A.2    Haas, S.3    Blümel, G.4
  • 326
    • 84915353354 scopus 로고
    • The effect of pentosan polysulphate (SP54) on the fibrinolytic enzyme system: a proposal for the mode of action
    • (abstr) Marsh N.A. Gaffney P.J. The effect of pentosan polysulphate (SP54) on the fibrinolytic enzyme system: a proposal for the mode of action Prog Fibrinolysis VII 1985
    • (1985) Prog Fibrinolysis , vol.VII
    • Marsh, N.A.1    Gaffney, P.J.2
  • 327
    • 0022456546 scopus 로고
    • The effect of pentosan polysulphate (SP54) on the fibrinolytic enzyme system: an experimental animal study
    • Marsh N.A. Gaffney P.J. The effect of pentosan polysulphate (SP54) on the fibrinolytic enzyme system: an experimental animal study Folia Haematol 113 1986 255 261
    • (1986) Folia Haematol , vol.113 , pp. 255-261
    • Marsh, N.A.1    Gaffney, P.J.2
  • 328
    • 0022450475 scopus 로고
    • The effect of pentosan polysulphate (SP54) on the human fibrinolytic system
    • Gaffney P.J. Marsh N.A. The effect of pentosan polysulphate (SP54) on the human fibrinolytic system Folia Haematol 113 1986 262 271
    • (1986) Folia Haematol , vol.113 , pp. 262-271
    • Gaffney, P.J.1    Marsh, N.A.2
  • 329
    • 0022644490 scopus 로고
    • Tolerance and biological activity of pentosan polysulfate after intramuscular or subcutaneous administration for ten days in human volunteers
    • Sié P. Albarede J.L. Robert M. Bouloux C. Lansen J. Chigot C. Tolerance and biological activity of pentosan polysulfate after intramuscular or subcutaneous administration for ten days in human volunteers Thromb Haemost 55 1986 86 89
    • (1986) Thromb Haemost , vol.55 , pp. 86-89
    • Sié, P.1    Albarede, J.L.2    Robert, M.3    Bouloux, C.4    Lansen, J.5    Chigot, C.6
  • 330
    • 0018871125 scopus 로고
    • Some observations on the release of extrinsic and intrinsic plasminogen activators during exercise in man
    • Marsh N. Gaffney E. Some observations on the release of extrinsic and intrinsic plasminogen activators during exercise in man Haemostasis 9 1980 238 247
    • (1980) Haemostasis , vol.9 , pp. 238-247
    • Marsh, N.1    Gaffney, E.2
  • 331
    • 0023029511 scopus 로고
    • Anticoagulant activities of pentosan polysulphate (Hëmoclar) due to release of hepatic triglyceride lipase (HTGL)
    • Barrowcliffe T.W. Gray E. Merton R.E. Dawes J. Jennings C.A. Hubbard A.R. Anticoagulant activities of pentosan polysulphate (Hëmoclar) due to release of hepatic triglyceride lipase (HTGL) Thromb Haemost 56 1986 202 206
    • (1986) Thromb Haemost , vol.56 , pp. 202-206
    • Barrowcliffe, T.W.1    Gray, E.2    Merton, R.E.3    Dawes, J.4    Jennings, C.A.5    Hubbard, A.R.6
  • 332
    • 0022222060 scopus 로고
    • Effect of the heparinoid pentosan polysulphate (SP 54) on the functional properties of cultured bovine aortic endothelial cells
    • Delvos U. Paul J.E. Muller-Berghaus G. Effect of the heparinoid pentosan polysulphate (SP 54) on the functional properties of cultured bovine aortic endothelial cells Blut 51 1985 127 136
    • (1985) Blut , vol.51 , pp. 127-136
    • Delvos, U.1    Paul, J.E.2    Muller-Berghaus, G.3
  • 333
    • 85119814688 scopus 로고
    • Clinical and experimental data on the fibrinolytic action of pentosan polysulphate
    • Vinazzer H.A. Clinical and experimental data on the fibrinolytic action of pentosan polysulphate Progress in Fibrinolysis VII 1985 319 321
    • (1985) Progress in Fibrinolysis , vol.VII , pp. 319-321
    • Vinazzer, H.A.1
  • 334
    • 85119793291 scopus 로고
    • Influence of pentosan polysulfate sodium compared with other polyanionic compounds on the t-PA and PAL 1 activity
    • Klöcking H-P. Influence of pentosan polysulfate sodium compared with other polyanionic compounds on the t-PA and PAL 1 activity Perfusion Suppl 2 1994 32 38
    • (1994) Perfusion Suppl , vol.2 , pp. 32-38
    • Klöcking, H-P.1
  • 335
    • 85119796581 scopus 로고
    • Profibrinolytic and anticoagulant properties of the pentosan polysulphate derivative bego 0391
    • Klöcking H-P. Hauptmann J. Richter M. Profibrinolytic and anticoagulant properties of the pentosan polysulphate derivative bego 0391 XIth Meeting of the International Society of Haematology European and African Division Basel, Switzerland August 31 to September 6, 1991
    • (1991)
    • Klöcking, H-P.1    Hauptmann, J.2    Richter, M.3
  • 336
    • 0028102606 scopus 로고
    • Acute t-PA releasing effect of supersulphated low molecular weight heparins
    • Klöcking H-P. Acute t-PA releasing effect of supersulphated low molecular weight heparins Fibrinolysis 8 1994 75 77
    • (1994) Fibrinolysis , vol.8 , pp. 75-77
    • Klöcking, H-P.1
  • 337
    • 0022617455 scopus 로고
    • Release of plasminogen activator by pentosan polysulphate
    • Klöcking H-P. Markwardt F. Release of plasminogen activator by pentosan polysulphate Thromb Res 41 1986 739 744
    • (1986) Thromb Res , vol.41 , pp. 739-744
    • Klöcking, H-P.1    Markwardt, F.2
  • 338
    • 85119816069 scopus 로고
    • Studies on profibrinolytic and anticoagulant properties of calcium pentosan polysulphate
    • Klöcking H-P. Richter M. Hauptmann J. Studies on profibrinolytic and anticoagulant properties of calcium pentosan polysulphate Naunyn Schmiedebergs Arch Pharmacol 344 1991 R54
    • (1991) Naunyn Schmiedebergs Arch Pharmacol , vol.344 , pp. R54
    • Klöcking, H-P.1    Richter, M.2    Hauptmann, J.3
  • 339
    • 10844260560 scopus 로고
    • Influence of pentosan polysulfate sodium compared with other polyanionic compounds on the t-PA and PAI-1 activity
    • Klöcking H-P. Influence of pentosan polysulfate sodium compared with other polyanionic compounds on the t-PA and PAI-1 activity Ann Hemat 70 Suppl I 1995 A39
    • (1995) Ann Hemat , vol.70 , Issue.Suppl I , pp. A39
    • Klöcking, H-P.1
  • 340
    • 0025349665 scopus 로고
    • Anticoagulant and antithrombotic effects of chemically modified heparins and pentosanpolysulfate
    • Krupinski K. Breddin H.K. Casu B. Anticoagulant and antithrombotic effects of chemically modified heparins and pentosanpolysulfate Haemostasis 20 1990 81 92
    • (1990) Haemostasis , vol.20 , pp. 81-92
    • Krupinski, K.1    Breddin, H.K.2    Casu, B.3
  • 341
    • 0020674838 scopus 로고
    • Laser-induced thrombi in rat mesenteric vessels and anti-thrombotic drugs
    • Weichert W. Pauliks V. Breddin H.K. Laser-induced thrombi in rat mesenteric vessels and anti-thrombotic drugs Haemostasis 13 1983 61 71
    • (1983) Haemostasis , vol.13 , pp. 61-71
    • Weichert, W.1    Pauliks, V.2    Breddin, H.K.3
  • 342
    • 0029866306 scopus 로고    scopus 로고
    • The action of polyanionic agents defibrotide and pentosan polysulfate on fibrinolytic activity in the laboratory rat
    • Jamieson A. Alcock P. Tuffin D.P. The action of polyanionic agents defibrotide and pentosan polysulfate on fibrinolytic activity in the laboratory rat Fibrinolysis 10 1996 27 35
    • (1996) Fibrinolysis , vol.10 , pp. 27-35
    • Jamieson, A.1    Alcock, P.2    Tuffin, D.P.3
  • 343
    • 0014222632 scopus 로고
    • The thrombolytic effect of heparin and a heparin-like substance, SP 54
    • FitzGerald D.E. Szeto I.L.F. Spero J. Lewis J.H. The thrombolytic effect of heparin and a heparin-like substance, SP 54 Thromb Diath Haem 17 1967 418 422
    • (1967) Thromb Diath Haem , vol.17 , pp. 418-422
    • FitzGerald, D.E.1    Szeto, I.L.F.2    Spero, J.3    Lewis, J.H.4
  • 344
    • 0002901147 scopus 로고
    • Pentosanpolysulfate treatment in osteoarthritis, serological parameters which could correlate with clinical response
    • Verbruggen G. Veys E.M. Ghosh P. Cullis-Hill D. Pentosanpolysulfate treatment in osteoarthritis, serological parameters which could correlate with clinical response Osteoarthritis Cart 2 1994 60
    • (1994) Osteoarthritis Cart , vol.2 , pp. 60
    • Verbruggen, G.1    Veys, E.M.2    Ghosh, P.3    Cullis-Hill, D.4
  • 345
    • 0022350720 scopus 로고
    • Fat embolism and osteonecrosis
    • Jones J.P. Fat embolism and osteonecrosis Orthop Clin North Am 16 1985 595 633
    • (1985) Orthop Clin North Am , vol.16 , pp. 595-633
    • Jones, J.P.1
  • 347
    • 8044259595 scopus 로고
    • The clearing effect of xylane sulfate polyesters on plasma lipids
    • Brunaud M. Segal V. Ravold J. Raveux R. The clearing effect of xylane sulfate polyesters on plasma lipids Prog Biochem Pharmacol 3 1967 393 402
    • (1967) Prog Biochem Pharmacol , vol.3 , pp. 393-402
    • Brunaud, M.1    Segal, V.2    Ravold, J.3    Raveux, R.4
  • 348
    • 84911266069 scopus 로고
    • Studies on the effect of xylane sulfate polyesters on the lipid composition of blood serum in rats receiving a high-fat diet
    • Raveux R. Ravold V. Segal V. Brunaud M. Studies on the effect of xylane sulfate polyesters on the lipid composition of blood serum in rats receiving a high-fat diet Prog Biochem Pharmacol 2 1967 451 458
    • (1967) Prog Biochem Pharmacol , vol.2 , pp. 451-458
    • Raveux, R.1    Ravold, V.2    Segal, V.3    Brunaud, M.4
  • 349
    • 85119802161 scopus 로고
    • Calcium pentosan polysuphate (CaPPS): an orally-active pleotropic osteoarthritis drug (POD) stimulates the release of superoxide dismutase (SOD) and lipases into canine plasma
    • Cullis-Hill D. Bellenger C. Bowman L. Ghosh P. Calcium pentosan polysuphate (CaPPS): an orally-active pleotropic osteoarthritis drug (POD) stimulates the release of superoxide dismutase (SOD) and lipases into canine plasma Rheumatology in Europe 24 1995
    • (1995) Rheumatology in Europe , vol.24
    • Cullis-Hill, D.1    Bellenger, C.2    Bowman, L.3    Ghosh, P.4
  • 350
    • 0031019866 scopus 로고    scopus 로고
    • A comparison of the lipolytic and anticoagulative properties of heparin and pentosan polysulfate in the thoroughbred horse
    • Orme C.E. Harris R.C. A comparison of the lipolytic and anticoagulative properties of heparin and pentosan polysulfate in the thoroughbred horse Acta Physiol Scand 159 1997 179 185
    • (1997) Acta Physiol Scand , vol.159 , pp. 179-185
    • Orme, C.E.1    Harris, R.C.2
  • 351
    • 0021916399 scopus 로고
    • The effects of postheparin plasma lipases on anti-XA clotting activity
    • Williams S.P. Barrowcliffe T.W. The effects of postheparin plasma lipases on anti-XA clotting activity Thromb Res 37 1985 371 377
    • (1985) Thromb Res , vol.37 , pp. 371-377
    • Williams, S.P.1    Barrowcliffe, T.W.2
  • 352
    • 76549192506 scopus 로고
    • Investigations on the treatment of the hyperlipaemic atherosclerosis with SP54
    • Zeller W. Schön H. Aladag I. Investigations on the treatment of the hyperlipaemic atherosclerosis with SP54 Med Welt 42 1964 2231 2238
    • (1964) Med Welt , vol.42 , pp. 2231-2238
    • Zeller, W.1    Schön, H.2    Aladag, I.3
  • 353
    • 2042537950 scopus 로고    scopus 로고
    • Disease modification in osteoarthritis: relationship of macrophage procoagulant activity and haematological parameter to symptoms in patientsreceiving pentosan polysulphate
    • Edelman J. Anderson J. Ghosh P. Disease modification in osteoarthritis: relationship of macrophage procoagulant activity and haematological parameter to symptoms in patientsreceiving pentosan polysulphate Osteoarthritis Cart 4 1996 iv v
    • (1996) Osteoarthritis Cart , vol.4 , pp. iv-v
    • Edelman, J.1    Anderson, J.2    Ghosh, P.3
  • 354
    • 8244242591 scopus 로고
    • Stimulation of peripheral blood mononuclear cells by cartilage degradation products
    • Anderson J. Bansal M. Ghosh P. Stimulation of peripheral blood mononuclear cells by cartilage degradation products J Leukoc Biol 100 suppl 1 1993
    • (1993) J Leukoc Biol , vol.100 , Issue.suppl 1
    • Anderson, J.1    Bansal, M.2    Ghosh, P.3
  • 356
    • 0030098665 scopus 로고    scopus 로고
    • Systemic use of pentosan polysulphate in the treatment of osteoarthritis
    • Read R.A. Cullis-Hill D. Jones M.P. Systemic use of pentosan polysulphate in the treatment of osteoarthritis J Small Anim Pract 37 1996 108 114
    • (1996) J Small Anim Pract , vol.37 , pp. 108-114
    • Read, R.A.1    Cullis-Hill, D.2    Jones, M.P.3
  • 357
    • 0000704370 scopus 로고
    • A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow
    • Bouck G.R. Miller C.W. Taves C.L. A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow Vet Comp Orthop Traumatol 8 1995 177 183
    • (1995) Vet Comp Orthop Traumatol , vol.8 , pp. 177-183
    • Bouck, G.R.1    Miller, C.W.2    Taves, C.L.3
  • 358
    • 0002050082 scopus 로고
    • A double-blind placebocontrolled clinical study of a pleiotropic osteoarthritis drug (pentosan polysulphate, Cartrophen) in 105 patients withosteoarthritis (OA) of the knee and hip joints
    • Edelman J. March L. Ghosh P. A double-blind placebocontrolled clinical study of a pleiotropic osteoarthritis drug (pentosan polysulphate, Cartrophen) in 105 patients withosteoarthritis (OA) of the knee and hip joints Osteoarthritis Cartilage 2 1994 23
    • (1994) Osteoarthritis Cartilage , vol.2 , pp. 23
    • Edelman, J.1    March, L.2    Ghosh, P.3
  • 359
    • 0024268463 scopus 로고
    • Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy inpatients with osteoarthritis of the hip or knee
    • Bellamy N. Buchanan W.W. Goldsmith C.M. Campbell J. Stitt L.W. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy inpatients with osteoarthritis of the hip or knee J Rheumatol 15 1988 1833 1840
    • (1988) J Rheumatol , vol.15 , pp. 1833-1840
    • Bellamy, N.1    Buchanan, W.W.2    Goldsmith, C.M.3    Campbell, J.4    Stitt, L.W.5
  • 360
    • 85119806449 scopus 로고    scopus 로고
    • Verbruggen G, Ghosh P, Cullis-Hill D, Veys E, Xylan polysulphate has SMOAD activities in patients with inflammatory finger joint OA. Osteoarthritis and Cartilage (in press).
  • 361
    • 0141437736 scopus 로고    scopus 로고
    • A double-blind placebo-controlled study of intra-articular pentosan polysulphate (Cartrophen) in patients with gonarthritis: laboratory andclinical findings
    • Rasaratnam I. Ryan P. Bowman L. Smith M. Ghosh P. A double-blind placebo-controlled study of intra-articular pentosan polysulphate (Cartrophen) in patients with gonarthritis: laboratory andclinical findings Osteoarthritis Cartilage 4 1996 vi vii
    • (1996) Osteoarthritis Cartilage , vol.4 , pp. vi-vii
    • Rasaratnam, I.1    Ryan, P.2    Bowman, L.3    Smith, M.4    Ghosh, P.5
  • 362
    • 0024592590 scopus 로고
    • An enzyme-linked immunosorbent-assay for quantitation of hyaluronin (hyaluronic acid) in biological fluids
    • Kongtawelert P. Ghosh P. An enzyme-linked immunosorbent-assay for quantitation of hyaluronin (hyaluronic acid) in biological fluids Anal Biochem 178 1989 367 372
    • (1989) Anal Biochem , vol.178 , pp. 367-372
    • Kongtawelert, P.1    Ghosh, P.2
  • 363
    • 0024512277 scopus 로고
    • Degradation of proteoglycan aggregate by a cartilage metaloproteinase: evidence for the involvement of stromelysin in the generation of link protein heterogeneity in situ
    • Nguyen Q. Murphy G. Roughley P.J. Mort J.S. Degradation of proteoglycan aggregate by a cartilage metaloproteinase: evidence for the involvement of stromelysin in the generation of link protein heterogeneity in situ Biochem J 259 1989 61 67
    • (1989) Biochem J , vol.259 , pp. 61-67
    • Nguyen, Q.1    Murphy, G.2    Roughley, P.J.3    Mort, J.S.4
  • 364
    • 0027369012 scopus 로고
    • Fibroblast and neutrophil collagenases cleave at 2 sites in the cartilage aggrecan interglobular domain
    • Fosang A.J. Last K. Knauper V. Neame P.J. Murphy G. Hardingham T.E. Fibroblast and neutrophil collagenases cleave at 2 sites in the cartilage aggrecan interglobular domain Biochem J 295 1993 273 276
    • (1993) Biochem J , vol.295 , pp. 273-276
    • Fosang, A.J.1    Last, K.2    Knauper, V.3    Neame, P.J.4    Murphy, G.5    Hardingham, T.E.6
  • 365
    • 0027428710 scopus 로고
    • Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein
    • Nguyen Q. Murphy G. Hughes C.E. Mort J.S. Roughley P.J. Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein Biochem J 295 1993 595 598
    • (1993) Biochem J , vol.295 , pp. 595-598
    • Nguyen, Q.1    Murphy, G.2    Hughes, C.E.3    Mort, J.S.4    Roughley, P.J.5
  • 366
    • 0026701977 scopus 로고
    • The interglobular domain of cartilage aggrecan is cleaved by pump, gelatinases, and cathepsin-B
    • Fosang A.J. Neame P.J. Last K. Hardingham T.E. Murphy G. Hamilton J.A. The interglobular domain of cartilage aggrecan is cleaved by pump, gelatinases, and cathepsin-B J Biol Chem 267 1992 9470 9474
    • (1992) J Biol Chem , vol.267 , pp. 9470-9474
    • Fosang, A.J.1    Neame, P.J.2    Last, K.3    Hardingham, T.E.4    Murphy, G.5    Hamilton, J.A.6
  • 367
    • 0030715322 scopus 로고    scopus 로고
    • ECM and cell surface proteolysis: Regulating cellular ecology
    • Werb Z. ECM and cell surface proteolysis: Regulating cellular ecology Cell 91 1997 439 442
    • (1997) Cell , vol.91 , pp. 439-442
    • Werb, Z.1
  • 368
    • 0024561514 scopus 로고
    • Degradation of type IX collagen by matrix metalloproteinase 3 (stromelysin) from human rheumatoid synovial cells
    • Okada Y. Konomi H. Yada T. Kimata K. Nagase H. Degradation of type IX collagen by matrix metalloproteinase 3 (stromelysin) from human rheumatoid synovial cells FEBS Lett 244 1989 473 476
    • (1989) FEBS Lett , vol.244 , pp. 473-476
    • Okada, Y.1    Konomi, H.2    Yada, T.3    Kimata, K.4    Nagase, H.5
  • 369
    • 0024323967 scopus 로고
    • Activation of matrix metalloproteinase 3 (stromelysin) and matrix metalloproteinase 2 (gelatinase) by human neutrophil elastase and cathepsin G
    • Okada Y. Nakanishi I. Activation of matrix metalloproteinase 3 (stromelysin) and matrix metalloproteinase 2 (gelatinase) by human neutrophil elastase and cathepsin G FEBS Lett 249 1989 353 356
    • (1989) FEBS Lett , vol.249 , pp. 353-356
    • Okada, Y.1    Nakanishi, I.2
  • 370
    • 0025949206 scopus 로고
    • Sites of stromelysin cleavage in collagen types II, IX, X and XI of cartilage
    • Wu J.J. Lark M.W. Chun L.E. Eyre D.R. Sites of stromelysin cleavage in collagen types II, IX, X and XI of cartilage J Biol Chem 266 1991 5625 5628
    • (1991) J Biol Chem , vol.266 , pp. 5625-5628
    • Wu, J.J.1    Lark, M.W.2    Chun, L.E.3    Eyre, D.R.4
  • 371
    • 0028127495 scopus 로고
    • Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E(373)-A(374) in the interglobular domain of cartilage aggrecan
    • Fosang A.J. Last K. Neame P.J. Murphy G. Knauper V. Tschesche H. Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E(373)-A(374) in the interglobular domain of cartilage aggrecan Biochem J 304 1994 347 351
    • (1994) Biochem J , vol.304 , pp. 347-351
    • Fosang, A.J.1    Last, K.2    Neame, P.J.3    Murphy, G.4    Knauper, V.5    Tschesche, H.6
  • 373
    • 0039167509 scopus 로고
    • Identification of MMP-13 (collagenase-3) as the major metalloproteinase expressed by chondrocytes during retinoic acid-induced matrix catabolism
    • Flannery C.R. Sandy J.D. Identification of MMP-13 (collagenase-3) as the major metalloproteinase expressed by chondrocytes during retinoic acid-induced matrix catabolism Trans Orthop Res Soc 41 1995 102
    • (1995) Trans Orthop Res Soc , vol.41 , pp. 102
    • Flannery, C.R.1    Sandy, J.D.2
  • 374
    • 0029310597 scopus 로고
    • Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease
    • Ries C. Petrides P.E. Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease Biol Chem Hoppe-Seyler 376 1995 345 355
    • (1995) Biol Chem Hoppe-Seyler , vol.376 , pp. 345-355
    • Ries, C.1    Petrides, P.E.2
  • 375
    • 0021170354 scopus 로고
    • Plasmin degradation of cartilage proteoglycan
    • Mochan E. Keler T. Plasmin degradation of cartilage proteoglycan Biochim Biophys Acta 800 1984 312 315
    • (1984) Biochim Biophys Acta , vol.800 , pp. 312-315
    • Mochan, E.1    Keler, T.2
  • 376
    • 0023756853 scopus 로고
    • Recombinant human interleukin-1 stimulates human articular cartilage to undergo resorption and human chondrocytes to produce both tissue-type andurokinase-type plasminogen activator
    • Campbell I.K. Piccoli D.S. Butler D.M. Singleton D.K. Hamilton J.A. Recombinant human interleukin-1 stimulates human articular cartilage to undergo resorption and human chondrocytes to produce both tissue-type andurokinase-type plasminogen activator Biochim Biophys Acta 967 1988 183 194
    • (1988) Biochim Biophys Acta , vol.967 , pp. 183-194
    • Campbell, I.K.1    Piccoli, D.S.2    Butler, D.M.3    Singleton, D.K.4    Hamilton, J.A.5
  • 377
    • 0025332578 scopus 로고
    • Effects of tumor necrosis factor-alpha and factorbeta on resorption of human articular cartilage and production of plasminogen activator by humanarticular cartilage
    • Campbell I.K. Piccoli D.S. Roberts M.J. Muirden K.D. Hamilton J.A. Effects of tumor necrosis factor-alpha and factorbeta on resorption of human articular cartilage and production of plasminogen activator by humanarticular cartilage Arthritis Rheum 33 1990 542 552
    • (1990) Arthritis Rheum , vol.33 , pp. 542-552
    • Campbell, I.K.1    Piccoli, D.S.2    Roberts, M.J.3    Muirden, K.D.4    Hamilton, J.A.5
  • 378
    • 0017684265 scopus 로고
    • The degradation of articular collagen by neutrophil proteinases
    • Starkey P. Barrett A.J. Burleigh M.C. The degradation of articular collagen by neutrophil proteinases Biochim Biophys Acta 4 83 1977 386 397
    • (1977) Biochim Biophys Acta , vol.4 , Issue.83 , pp. 386-397
    • Starkey, P.1    Barrett, A.J.2    Burleigh, M.C.3
  • 379
    • 0025353178 scopus 로고
    • Degradation of cartilage collagens type II, type IX, type X and type XI by enzymes derived from human articular chondrocytes
    • Gadher S.J. Eyre D.R. Wotton S.F. Schmid T.M. Woolley D.E. Degradation of cartilage collagens type II, type IX, type X and type XI by enzymes derived from human articular chondrocytes Matrix 10 1990 154 163
    • (1990) Matrix , vol.10 , pp. 154-163
    • Gadher, S.J.1    Eyre, D.R.2    Wotton, S.F.3    Schmid, T.M.4    Woolley, D.E.5
  • 380
    • 0023786345 scopus 로고
    • Susceptibility of cartilage collagens type II, IX, X, and XI to human synovial collagenase and neutrophil elastase
    • Gadher S.J. Eyre D.R. Duance V.C. Wotton S.F. Heck L.W. Schmid T.M. Susceptibility of cartilage collagens type II, IX, X, and XI to human synovial collagenase and neutrophil elastase Eur J Biochem 175 1988 1 7
    • (1988) Eur J Biochem , vol.175 , pp. 1-7
    • Gadher, S.J.1    Eyre, D.R.2    Duance, V.C.3    Wotton, S.F.4    Heck, L.W.5    Schmid, T.M.6
  • 381
    • 0028997493 scopus 로고
    • Biotin-labeled potato chymotrypsin inhibitor-1: a useful probe for the detection and quantitation of chymotrypsin-like serine proteinases on Western blots and its application in the detection of a serine proteinase synthesised by articular chondrocytes
    • Rodgers K.J. Melrose J. Ghosh P. Biotin-labeled potato chymotrypsin inhibitor-1: a useful probe for the detection and quantitation of chymotrypsin-like serine proteinases on Western blots and its application in the detection of a serine proteinase synthesised by articular chondrocytes Anal Biochem 227 1995 129 134
    • (1995) Anal Biochem , vol.227 , pp. 129-134
    • Rodgers, K.J.1    Melrose, J.2    Ghosh, P.3
  • 382
    • 0023595196 scopus 로고
    • Proteinases and their inhibitors in normal and osteoarthritic articular cartilage
    • Yamada H. Nakagawa T. Stephens R.W. Nagai Y. Proteinases and their inhibitors in normal and osteoarthritic articular cartilage Biomed Res 8 1987 289 300
    • (1987) Biomed Res , vol.8 , pp. 289-300
    • Yamada, H.1    Nakagawa, T.2    Stephens, R.W.3    Nagai, Y.4
  • 383
    • 0025061478 scopus 로고
    • Susceptibility of the cartilage rollagens types types II, IX and XI to degradation by the cysteine proteinases, cathepsins B and L
    • Maciewicz R.A. Wotton S.F. Etherington D.J. Duance V.C. Susceptibility of the cartilage rollagens types types II, IX and XI to degradation by the cysteine proteinases, cathepsins B and L FEBS Lett 269 1990 189 193
    • (1990) FEBS Lett , vol.269 , pp. 189-193
    • Maciewicz, R.A.1    Wotton, S.F.2    Etherington, D.J.3    Duance, V.C.4
  • 384
    • 0028907722 scopus 로고
    • Cathepsin B in osteoarthritis: Zonal variation of enzyme activity in human femoral head cartilage
    • Baici A. Hörler D. Lang A Merlin C. Kissling R. Cathepsin B in osteoarthritis: Zonal variation of enzyme activity in human femoral head cartilage Ann Rheum Dis 54 1995 281 288
    • (1995) Ann Rheum Dis , vol.54 , pp. 281-288
    • Baici, A.1    Hörler, D.2    Lang, A3    Merlin, C.4    Kissling, R.5
  • 385
    • 0021344717 scopus 로고
    • Extracellular presence of the lysosomal proteinase Cathepsin B in rheumatoid synovium and its activity at neutral pH
    • Mort J.S. Recklies A.D. Poole A.R. Extracellular presence of the lysosomal proteinase Cathepsin B in rheumatoid synovium and its activity at neutral pH Arthritis Rheum 27 1984 509 515
    • (1984) Arthritis Rheum , vol.27 , pp. 509-515
    • Mort, J.S.1    Recklies, A.D.2    Poole, A.R.3
  • 387
    • 0015802186 scopus 로고
    • Cathepsin D activity in normal and osteoarthritic human cartilage
    • Sapolsky A.I. Altman R.D. Howell DS. Cathepsin D activity in normal and osteoarthritic human cartilage Fed Proc 32 1973 1489 1493
    • (1973) , pp. 1489-1493
    • Sapolsky, A.I.1    Altman, R.D.2    Howell, DS.3
  • 388
    • 0015978285 scopus 로고
    • Cathepsin D in cartilage: the immunohistochemical demonstration of extracellular enzyme in normal and pathological conditions
    • Poole A.R. Hembry R.M. Dingle J.T. Cathepsin D in cartilage: the immunohistochemical demonstration of extracellular enzyme in normal and pathological conditions J Cell Sci 14 1974 139 161
    • (1974) J Cell Sci , vol.14 , pp. 139-161
    • Poole, A.R.1    Hembry, R.M.2    Dingle, J.T.3
  • 389
    • 0025012380 scopus 로고
    • Mode of acativation of the precursor to cathepsin L: implication for matrix degradation in arthritis
    • (Suppl) Maciewicz R.A. Wardale R-J. Wotton S.F. Duance V.C. Etherington D.J. Mode of acativation of the precursor to cathepsin L: implication for matrix degradation in arthritis Bio Chem Hopp-Seyler 371 1990 223 228
    • (1990) Bio Chem Hopp-Seyler , vol.371 , pp. 223-228
    • Maciewicz, R.A.1    Wardale, R-J.2    Wotton, S.F.3    Duance, V.C.4    Etherington, D.J.5


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