메뉴 건너뛰기




Volumn 4, Issue 7, 2008, Pages 505-511

Use of allopurinol to optimize thiopurine immunomodulator efficacy in inflammatory bowel disease

Author keywords

6 mercaptopurine; 6 methylmercaptopurine; 6 thioguanine nucleotide; Allopurinol; Azathioprine; Inflammatory bowel disease

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; 6 THIOURIC ACID; ALLOPURINOL; AMINOSALICYLIC ACID DERIVATIVE; AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; DRUG METABOLITE; IMMUNOMODULATING AGENT; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; METHOTREXATE; METHYLMERCAPTOPURINE; PREDNISOLONE; PREDNISONE; TIOGUANINE; XANTHINE OXIDASE INHIBITOR;

EID: 49149113484     PISSN: 15547914     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (17)

References (25)
  • 3
    • 39149120115 scopus 로고    scopus 로고
    • Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis
    • CD000478
    • Timmer A, McDonald JW, Macdonald JK. Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev. 2007;(1):CD000478.
    • (2007) Cochrane Database Syst Rev , Issue.1
    • Timmer, A.1    McDonald, J.W.2    Macdonald, J.K.3
  • 4
    • 4844225774 scopus 로고    scopus 로고
    • Review article: Treatment of perianal fistulizing Crohn's disease
    • Rutgeerts P. Review article: treatment of perianal fistulizing Crohn's disease. Aliment Pharmacol Ther. 2004;(20 suppl 4):106-110.
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.SUPPL. 4 , pp. 106-110
    • Rutgeerts, P.1
  • 5
    • 34548130215 scopus 로고    scopus 로고
    • Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease
    • Vermeire S, Noman M, Van Assche G, Baert F, D'Haens G, Rutgeerrs P. Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease. Gut. 2007;56:1226-1231.
    • (2007) Gut , vol.56 , pp. 1226-1231
    • Vermeire, S.1    Noman, M.2    Van Assche, G.3    Baert, F.4    D'Haens, G.5    Rutgeerrs, P.6
  • 6
    • 0034067784 scopus 로고    scopus 로고
    • Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease
    • Dubinsky MC, Lamothe S, Yang HY, Targan SR, Sinnett D, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology. 2000;118:705-713.
    • (2000) Gastroenterology , vol.118 , pp. 705-713
    • Dubinsky, M.C.1    Lamothe, S.2    Yang, H.Y.3    Targan, S.R.4    Sinnett, D.5
  • 7
    • 33646011261 scopus 로고    scopus 로고
    • Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: A meta-analysis
    • Osterman MT, Kundu R, Lichtenstein GR, Lewis JD. Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology. 2006;130:1047-1053.
    • (2006) Gastroenterology , vol.130 , pp. 1047-1053
    • Osterman, M.T.1    Kundu, R.2    Lichtenstein, G.R.3    Lewis, J.D.4
  • 8
    • 0036202803 scopus 로고    scopus 로고
    • 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease
    • Dubinsky MC, Yang H, Hassard PV, Seidman EG, Kam LY, et al. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. Gastroenterology. 2002;122:904-915.
    • (2002) Gastroenterology , vol.122 , pp. 904-915
    • Dubinsky, M.C.1    Yang, H.2    Hassard, P.V.3    Seidman, E.G.4    Kam, L.Y.5
  • 9
    • 0036790212 scopus 로고    scopus 로고
    • Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease
    • Ansari A, Hassan C, Duley J, Marinaki A, Shobowale-Bakre EM, et al. Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease. Aliment Pharmacol Ther. 2002;16:1743-1750.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1743-1750
    • Ansari, A.1    Hassan, C.2    Duley, J.3    Marinaki, A.4    Shobowale-Bakre, E.M.5
  • 10
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet. 1980;32:651-662.
    • (1980) Am J Hum Genet , vol.32 , pp. 651-662
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 11
    • 42149148677 scopus 로고    scopus 로고
    • Trinucleotide repeat variants in the promoter of the thiopurine S-methyltransferase gene of patients exhibiting ultra-high enzyme activity
    • Roberts RL, Gearry RB, Bland MV, Sies CW, George PM, et al. Trinucleotide repeat variants in the promoter of the thiopurine S-methyltransferase gene of patients exhibiting ultra-high enzyme activity. Pharmacogenet Genomics. 2008; 18:434-438.
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 434-438
    • Roberts, R.L.1    Gearry, R.B.2    Bland, M.V.3    Sies, C.W.4    George, P.M.5
  • 12
    • 0030657957 scopus 로고    scopus 로고
    • Olsalazine and 6-mercaptopurine-related bone marrow suppression: A possible drug-drug interaction
    • Lewis LD, Benin A, Szumlanski CL, Otterness DM, Lennard L, et al. Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction. Clin Pharmacol Ther. 1997;62:464-475.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 464-475
    • Lewis, L.D.1    Benin, A.2    Szumlanski, C.L.3    Otterness, D.M.4    Lennard, L.5
  • 13
    • 0028917479 scopus 로고
    • Sulphasalazine inhibition of thiopurine methyltransferase: Possible mechanism for interaction with 6-mercaptopurine and azathioprine
    • Szumlanski CL, Weinshilboum RM. Sulphasalazine inhibition of thiopurine methyltransferase: possible mechanism for interaction with 6-mercaptopurine and azathioprine. Br J Clin Pharmacol. 1995;39:456-459.
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 456-459
    • Szumlanski, C.L.1    Weinshilboum, R.M.2
  • 14
    • 33646778817 scopus 로고    scopus 로고
    • 5-aminosalicylate therapy is associated with higher 6-thioguanine levels in adults and children with inflammatory bowel disease in remission on 6-mercaptopurine or azathioprine
    • Hande S, Wilson-Rich N, Bousvaros A, Zholudev A, Maurer R, et al. 5-aminosalicylate therapy is associated with higher 6-thioguanine levels in adults and children with inflammatory bowel disease in remission on 6-mercaptopurine or azathioprine. Inflamm Bowel Dis. 2006;12:251-257.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 251-257
    • Hande, S.1    Wilson-Rich, N.2    Bousvaros, A.3    Zholudev, A.4    Maurer, R.5
  • 16
    • 0029793841 scopus 로고    scopus 로고
    • Azathioprine and allopurinol: The price of an avoidable drug interaction
    • Kennedy DT, Hayney MS, Lake KD. Azathioprine and allopurinol: the price of an avoidable drug interaction. Ann Pharmacother. 1996;30:951-954.
    • (1996) Ann Pharmacother , vol.30 , pp. 951-954
    • Kennedy, D.T.1    Hayney, M.S.2    Lake, K.D.3
  • 17
    • 0025296537 scopus 로고
    • Azathioprine and allopurinol: A potentially dangerous combination
    • Venkat Raman G, Sharman VL, Lee HA. Azathioprine and allopurinol: a potentially dangerous combination. J Intern Med. 1990;228:69-71.
    • (1990) J Intern Med , vol.228 , pp. 69-71
    • Venkat Raman, G.1    Sharman, V.L.2    Lee, H.A.3
  • 18
    • 0027161587 scopus 로고
    • Low-dose allopurinol plus azathioprine/cyclosporin/prednisolone, a novel immunosuppressive regimen
    • Chocair P, Duley J, Simmonds HA, Cameron JS, Ianhez L, et al. Low-dose allopurinol plus azathioprine/cyclosporin/prednisolone, a novel immunosuppressive regimen. Lancet. 1993;342:83-84.
    • (1993) Lancet , vol.342 , pp. 83-84
    • Chocair, P.1    Duley, J.2    Simmonds, H.A.3    Cameron, J.S.4    Ianhez, L.5
  • 19
    • 24344480999 scopus 로고    scopus 로고
    • Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine
    • Sparrow MP, Hande SA, Friedman S, Lim WC, Reddy SI, et al. Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine. Aliment Pharmacol Ther. 2005;22:441-446.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 441-446
    • Sparrow, M.P.1    Hande, S.A.2    Friedman, S.3    Lim, W.C.4    Reddy, S.I.5
  • 20
    • 33846820178 scopus 로고    scopus 로고
    • Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine
    • Sparrow MP, Hande SA, Friedman S, Cao D, Hanauer SB. Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine. Clin Gastroenterol Hepatol. 2007;5:209-214.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 209-214
    • Sparrow, M.P.1    Hande, S.A.2    Friedman, S.3    Cao, D.4    Hanauer, S.B.5
  • 22
    • 0014964022 scopus 로고
    • Depletion of erythrocyte phosphoribosylpyrophosphate in man
    • Fox IH, Wyngaarden JB, Kelley WN. Depletion of erythrocyte phosphoribosylpyrophosphate in man. N Engl J Med. 1970;283:1177-1182.
    • (1970) N Engl J Med , vol.283 , pp. 1177-1182
    • Fox, I.H.1    Wyngaarden, J.B.2    Kelley, W.N.3
  • 23
    • 0027415547 scopus 로고
    • Allopurinol transport in human erythrocytes
    • Razavi M, Kraupp M, Marz R. Allopurinol transport in human erythrocytes. Biochem Pharmacol. 1993;45:893-897.
    • (1993) Biochem Pharmacol , vol.45 , pp. 893-897
    • Razavi, M.1    Kraupp, M.2    Marz, R.3
  • 24
    • 0036227759 scopus 로고    scopus 로고
    • Progress towards the discovery of xanthine oxidase inhibitors
    • Borges F, Fernandes E, Roleira F. Progress towards the discovery of xanthine oxidase inhibitors. Curr Med Chem. 2002;9:195-217.
    • (2002) Curr Med Chem , vol.9 , pp. 195-217
    • Borges, F.1    Fernandes, E.2    Roleira, F.3
  • 25
    • 0028277317 scopus 로고
    • The inhibitory effects of allopurinol on the production and cytotoxicity of tumor necrosis factor
    • Olah T, Regely K, Mandi Y. The inhibitory effects of allopurinol on the production and cytotoxicity of tumor necrosis factor. Naunyn Schmiedebergs Arch Pharmacol. 1994;350:96-99.
    • (1994) Naunyn Schmiedebergs Arch Pharmacol , vol.350 , pp. 96-99
    • Olah, T.1    Regely, K.2    Mandi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.