Risk factors for discontinuing drug therapy among children with ADHD

Health Services and Outcomes Research Methodology

Volumn 8, Issue 3, 2008, Pages 134-158

  Bokhari, Farasat A S ^a   Heiland, Frank ^a   Levine, Peter ^b   Ray, G Thomas ^c  

^a FLORIDA STATE UNIVERSITY   (United States)

^b KAISER PERMANENTE MEDICAL CENTER   (United States)

^c DIVISION OF RESEARCH   (United States)

Author keywords

ADHD; Adherence; Compliance; Drug therapy; Duration; Hazard models

Indexed keywords

AMPHETAMINE; METHYLPHENIDATE;

AFRICAN AMERICAN; ARTICLE; ASIA; ATTENTION DEFICIT DISORDER; CAUCASIAN; CHILD; CONTROLLED STUDY; COVARIANCE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; EARLY DIAGNOSIS; FEMALE; FOLLOW UP; HEALTH CARE POLICY; HEALTH HAZARD; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL FEE; MEDICAL RECORD; PATIENT COMPLIANCE; PHARMACY; PRESCRIPTION; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; SEASONAL VARIATION; SEX DIFFERENCE; TREATMENT DURATION;

EID: 49149095275     PISSN: 13873741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10742-008-0035-x     Document Type: Article

References (51)

1. Bagchi, A.D., Esposito, D., Myoung, K., Verdier, J., Bencio, D.: Utilization of, and adherence to, drug therapy among medicaid beneficiaries with congestive heart failure. Clin. Ther. 29(8), 1771-1783 (2007)
2. Barkley, R.A., Fischer, M., Edelbrock, C.S., Smallish, L.: The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study. J. Am. Acad. Child Adolesc. Psychiatry 29(4), 546-587 (1990)
3. Barkley, R.A., Murphy, K.R., Kwasnik, D.: Motor vehicle driving competencies and risks in teens and young adults with attention deficit hyperactivity disorder. Pediatrics 98(6 Pt 1), 1089-1095 (1996)
4. Barkley, R.A., Fischer, M., Smallish, L., Fletcher, K.: Young adult outcome of hyperactive children: Adaptive functioning in major life activities. J. Am. Acad. Child Adolesc. Psychiatry 45(2), 192-202 (2006)
5. Biederman, J., Wilens, T., Mick, E., Spencer, T.J., Faraone, S.V.: Psychoactive substance use disorders in adults with attention deficit hyperactivity disorder (ADHD): Effects of ADHD and psychiatric comorbidity. Am. J. Psychiatry 152(11), 1652-1658 (1995)
6. Biederman, J., Mick, E., Wozniak, J., Chen, L., Ouellette, C., Marrs, A. et al.: Attention-deficit hyperactivity disorder and juAenile mania: an overlooked comorbidity? J. Am. Acad. Child Adolesc. Psychiatry 35, 997-1008 (1996)
7. Bokhari, F.A.S., Mayes, R., Scheffler, R.M.: An analysis of the significant variation in psychostimulant use across the U.S. Pharmacoepidemiol. Drug Saf. 14(4), 267-275 (2005)
8. Cameron, A.C., Trivedi, P.K.: Microeconometrics: Methods and Applications. Cambridge University Press, Cambridge (2005)
9. Charach, A., Ickowicz, A., Schachar, R.: Stimulant treatment over five years: Adherence, effectiveness, and adverse effects. J. Am. Acad. Child Adolesc. Psychiatry 43(5), 559-567 (2004)
10. Corkum, P., Rimer, P., Schachar, R.: Parental knowledge of attention-deficit hyperactivity disorder and opinions of treatment options: Impact on enrollment and adherence to a 12-month treatment trial. Can. J. Psychiatry 44(10), 1043-1048 (1999)
11. Cox, E., Motheral, B., Henderson, R., Mager, D.: Geographic variation in the prevalence of stimulant medication use among children 5 to 14 years old: Results from a commercially insured U.S. sample. Pediatrics 111, 237-243 (2003)
12. dosReis, S., Magno, Z.J., Safer, D.J., Soeken, K.L., Mitchell, J.W. Jr., Ellwood, L.C.: Parental perceptions and satisfaction with stimulant medication for attention-deficit hyperactivity disorder. J. Dev. Behav. Pediatr. 24(3), 155-162 (2003)
13. Duan, N.: SmeAring estimate: a non-parametric retransformation method. J. Am. Stat. Assoc. 78(383), 605-610 (1983)
14. Faraone, S.V., Biederman, J., Zimmerman, B.: An analysis of patient adherence to treatment during a 1-year, open-label study of OROS methylphenidate in children with ADHD. J. Atten. Disord. (2007) (forthcoming). Online version poseted at journal website. doi: 10.1177/ 1087054706295663
15. Finney, J.W., Hook, R.J., Friman, P.C., Rapoff, M.A., Christophersen, E.R.: The overestimation of adherence to pediatric medical regimens. Child Health Care, Fall, 22(4), 297-304 (1993)
16. Firestone, P.: Factors associated with children's adherence to stimulant medication. Am. J. Orthopsychiatry 52(3), 447-457 (1982)
17. Gau, S.S.F., Shen, H.-Y., Chou, M.-C., Tang, C.-S., Chiu, Y.-N., Gau, C.-S.: Determinants of adherence to methylphenidate and the impact of poor adherence on maternal and family measures. J. Child Adolesc. Psychopharmacol. 16(3), 286-297 (2006)
18. Greenberg, R.N.: Overview of patient compliance with medication dosing: a literature review. Clin. Ther. 6(5), 592-599 (1984)
19. Greenhill, L.L., Pliszka, S., Dulcan, M.K., Bernet, W., Arnold, V., Beitchman, J., Benson, R.S., Bukstein, O., Kinlan, J., McClellan, J., Rue, D., Shaw, J., Stock, S., AACAP: Practice parameter for the use of stimulant medications in the treatment of children, adolescents, and adults. J. Am. Acad. Child Adolesc. Psychiatry 41(2 Suppl), 26S-49S (2002)
20. Hack, S., Chow, B.: Pediatric psychotropAc medication compliance: a literature review and research-based suggestions for improving treatment compliance. J. Child Adolesc. Psychopharmacol., Spring, 11(1), 59-67 (2001)
21. Heckman, J., Singer, B.: A method for minimizing the impact of distributional assumptions in econometric models for duration data. Econometrica 52(2), 271-320 (1984)
22. Hugtenburg, J.G., Griekspoor, J.E., De Boer, I., Heerdink, E.R., Tso, Y.H., EgberUs, A.C.G.: Methylphenidate: use in daily practice. Pharm. World Sci. 27(3), 197-201 (2005)
23. Huskamp, H.A., Deverka, P.A., Epstein, A.M., Epstein, R.S., McGuigan, K.A., Muriel, A.C., Frank, R.G.: Impact of 3-tier formularies on drug treatment of attention-deficit/hyperactivity disorder in children. Arch. Gen. Psychiatry 62(4), 435-441 (2005)
24. Jensen, P.S., Hinshaw, S.P., Swanson, J.M., Greenhill, L.L., Conners, C.K., Arnold, L.E., Abikoff, H.B., Elliott, G., Hechtman, L., Hoza, B., March, J.S., Newcorn, J.H., Severe, J.B., Vitiello, B., Wells, K., Wigal, T.: Findings from the NIMH Multimodal Treatment Study of ADHD (MTA): Implications and applications for primary care providers. J. Dev. Behav. Pediatr. 22(1), 60-73 (2001)
25. Kalbfleisch, J.D., Prentice, R.L.: The Statistical Analysis of Failure Time Data, 2nd edn. John Wiley & Sons, Ltd., New Jersey (2002)
26. Kemner, J.E., Lage, M.J.: Effect of methylphenidate formulation on treatment patterns and use of emergency room services. Am. J. Health Syst. Pharm. 63(4), 317-322 (2006)
27. Lage, M., Hwang, P.: Effect of methylphenidate formulation for attention deficit hyperactivity disorder on patterns and outcomes of treatment. J. Child Adolesc. Psychopharmacol. 14(4), 575-581 (2004)
28. La Greca, A.M.: Issues in adherence with pediatric regimens. J. Pediatr. Psychol. 15(4), 423-436 (1990)
29. Mannuzza, S., Klein, R.G., Bessler, A., Malloy, P., Hynes, M.E.: Educational and occupational outcome of hyperactive boys grown up. J. Am. Acad. Child Adolesc. Psychiatry 36(9), 1222-1227 (1997)
30. Marcus, S.C., Wan, G.J., Kemner, J.E., Olfson, M.: Continuity of methylphenidate treatment for attention-deficit/hyperactivity disorder. Arch. Pediatr. Adolesc. Med. 159(9), 572-578 (2005)
31. Meyer, B.D.: Unemployment insurance and unemployment spells. Econometrica 58(4), 757-782 (1990)
32. Miller, A.R., Lalonde, C.E., McGrail, K.M.: Children's persistence with methylphenidate therapy: A population-based study. Can. J. Psychiatry 49(11), 761-868 (2004)
33. Monastra, V.J.: Overcoming the barriers to effective treatment for attention-deficit/hyperactivity disorder: A neuro-educational approach. Int. J. Psychophysiol. 58(1), 71-80 (2005)
34. MTA Cooperative Group: National Institute of Mental Health Multimodal Treatment Study of ADHD follow-up: 24-month outcomes of treatment strategies for attention-deficit/hyperactivity disorder. Pediatrics 113(4), 754-761 (2004)
35. MTA Cooperative Group, Hinshaw, S.P., Elliott, G.R., Conncers, C.K., Wells, K.C., March, J., Swanson, J., Wigal, T., Cantwell, D.P., Abikoff, H.B., Hecthman, L., Greenhill, L.L., Newcorn, J.H.: A 14-month randomized clinical trial of treatment strategies for ADHD. Arch. Gen. Psychiatry 56, 1073-1086 (1999)
36. Perwien, A.R., Hall, J., Swensen, A., Swindle, R.: Stimulant treatment patterns and compliance in children and adults with newly treated attention-deficit/hyperactivity disorder. J. Manag. Care Pharm. 10(2), 122-129 (2004)
37. Prentice, R.L., Gloeckler, L.A.: Regression analysis of grouped survival data with application to breast cancer data. Biometrics 34, 57-67 (1978)
38. Rizzo, J.A., Simons, W.R.: Variations in compliance among hypertensive patients by drug class: Implications for health care costs. Clin. Ther. 19(6), 1446-1457 (1997)
39. Sanchez, R.J., Crismon, M.L., Barner, J.C., Bettinger, T., Wilson, J.P.: Assessment of adherence measures with different stimulants among children and adolescents. Pharmacotherapy 25(7), 909-917 (2005)
40. Sax, L., Kautz, K.J.: Who first suggests the diagnosis of attention-deficit/hyperactivity disorder. Ann. Fam. Med. 1(3), 171-174 (2003)
41. Schectman, J.M., Nadkarni, M.M., Voss, J.D.: The association between diabetes metabolic control and drug adherence in an indigent population. Diabetes Care 25(6), 1015-1021 (2002)
42. Schneider, H., Eisenberg, D.: Who receives a diagnosis of attention-deficit/hyperactivity disorder in the United States elementary school population? Pediatrics 117(4), e601-e609 (2006)
43. Shope, J.T.: Medication compliance. Pediatr. Clin. North Am. 28(1), 5-21 (1981)
44. Sleator, E.K., Ullmann, R.K., von Neumann, A.: How do hyperactive children feel about taking stimulants and will they tell the doctor? Clin. Pediatr. 21(8), 474-479 (1982)
45. Spencer, T., Biederman, J., Wilens, T., Harding, M., O'Donnell, D., Griffin, S.: Pharmacotherapy of attention-deficit hyperactivity disorder across the life cycle. J. Am. Acad. Child Adolesc. Psychiatry 35 (4), 409-432 (1996)
46. Stevens, J., Harman, J.S., Kelleher, K.J.: Race/ethnicity and insurance status as factors associated with ADHD treatment patterns. J. Child Adolesc. Psychopharmacol. 15(1), 88-96 (2005)
47. Swanson, J.: Compliance with stimulants for attention-deficit/ hyperactivity disorder: Issues and approaches for improvement. CNS Drugs 17(2), 117-131 (2003)
48. Thiruchelvam, D., Charach, A., Schachar, R.J.: Moderators and mediators of long-term adherence to stimulant treatment in children with ADHD. J. Am. Acad. Child Adolesc. Psychiatry 40 (8), 922-928 (2001)
49. U.S. Census Bureau: America's families and living arrangements: 2006, Table AVG-2. U.S. Census Bureau, Population Division, Fertility & Family Statistics Branch, 2006. http://www.census.gov/population/www/ socdemo/hh-fam.html (last accessed 4/26/2008)
50. Williams, L.K., Joseph, C.L., Peterson, E.L., Moon, C., Xi, H., Krajenta, R., Johnson, R., Wells, K., Booza, J.C., Tunceli, K., Lafata, J.E., Johnson, C.C., Ownby, D.R., Enberg, R., Pladevall, M.: Race-ethnicity, crime, and other factors associated with adherence to inhaled corticosteroids. J. Allergy Clin. Immunol. 119(1), 168-175 (2007a)
51. Williams, L.K., Joseph, C.L., Peterson, E.L., Wells, K., Wang, M., Chowdhry, V.K., Walsh, M., Campbell, J., Rand, C.S., Apter, A.J., Lanfear, D.E., Tunceli, K., Pladevall, M.: Patients with asthma who do not fill their inhaled corticosteroids: A study of primary nonadherence. J. Allergy Clin. Immunol. 120(5), 1153-1159 (2007b)