Visualization of in situ intracellular aggregation of two cataract-associated human γ-crystallin mutants: Lose a tail, lose transparency

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 8, 2008, Pages 3483-3490

  Talla, Venu ^a   Srinivasan, Narayanaswamy ^b   Balasubramanian, Dorairajan ^a  

^a L V PRASAD EYE INSTITUTE   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; ENHANCED GREEN FLUORESCENT PROTEIN; GAMMA CRYSTALLIN; GAMMA D CRYSTALLIN; MUTANT PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; CRYGC PROTEIN, HUMAN; CRYSTALLIN; CRYSTALLIN GAMMAD, HUMAN; GREEN FLUORESCENT PROTEIN;

ADULT; AQUEOUS SOLUTION; ARTICLE; BACTERIAL STRAIN; CASE REPORT; CATARACT; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONGENITAL CATARACT; CONTROLLED STUDY; EPITHELIUM CELL; ESCHERICHIA COLI; GENE DELETION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNOFLUORESCENCE; MOLECULAR CLONING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPECTROSCOPY; WESTERN BLOTTING; WILD TYPE; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; DOMINANT GENE; GENETICS; LENS; METABOLISM; MIDDLE AGED; PROTEIN TERTIARY STRUCTURE; RAT; RETINA GANGLION CELL;

ANIMALS; BLOTTING, WESTERN; CATARACT; CELL CULTURE TECHNIQUES; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COS CELLS; CRYSTALLINS; EPITHELIAL CELLS; GAMMA-CRYSTALLINS; GENES, DOMINANT; GREEN FLUORESCENT PROTEINS; HUMANS; LENS, CRYSTALLINE; MICROSCOPY, CONFOCAL; MIDDLE AGED; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; RETINAL GANGLION CELLS; SEQUENCE DELETION; TRANSFECTION;

EID: 49049106786     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1114     Document Type: Article

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